메뉴 건너뛰기




Volumn 61, Issue 2, 2012, Pages 202-213

Intestinal renin-angiotensin system is stimulated after deletion of Lkb1

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CAPTOPRIL; CRE RECOMBINASE; DIPEPTIDYL CARBOXYPEPTIDASE; MITOGEN ACTIVATED PROTEIN KINASE; MUCIN; RENIN; SELUMETINIB;

EID: 84855203581     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-300046     Document Type: Article
Times cited : (24)

References (76)
  • 3
    • 0345107247 scopus 로고    scopus 로고
    • Complexes between the Lkb1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
    • Hawley SA, Boudeau J, Reid JL, et al. Complexes between the Lkb1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2003;2:28.
    • (2003) J Biol , vol.2 , pp. 28
    • Hawley, S.A.1    Boudeau, J.2    Reid, J.L.3
  • 5
    • 59249096211 scopus 로고    scopus 로고
    • Lkb1 deficiency alters goblet and Paneth cell differentiation in the small intestine
    • Shorning BY, Zabkiewicz J, McCarthy A, et al. Lkb1 deficiency alters goblet and Paneth cell differentiation in the small intestine. PLoS ONE 2009;4:e4264.
    • (2009) PLoS ONE , vol.4
    • Shorning, B.Y.1    Zabkiewicz, J.2    McCarthy, A.3
  • 6
    • 0017413556 scopus 로고
    • Renin angiotensin system: Biochemistry and mechanisms of action
    • Peach MJ. Renineangiotensin system: biochemistry and mechanisms of action. Physiol Rev 1977;57:313-70. (Pubitemid 8097628)
    • (1977) Physiological Reviews , vol.57 , Issue.2 , pp. 313-370
    • Peach, M.J.1
  • 7
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renineangiotensin systems
    • Paul M, Poyan Mehr A, Kreutz R. Physiology of local renineangiotensin systems. Physiol Rev 2006;86:747-803.
    • (2006) Physiol Rev , vol.86 , pp. 747-803
    • Paul, M.1    Poyan Mehr, A.2    Kreutz, R.3
  • 8
    • 35348912549 scopus 로고    scopus 로고
    • Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane
    • DOI 10.1113/jphysiol.2007.138578
    • Wong TP, Debnam ES, Leung PS. Involvement of an enterocyte renineangiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane. J Physiol 2007;584:613-23. (Pubitemid 47578343)
    • (2007) Journal of Physiology , vol.584 , Issue.2 , pp. 613-623
    • Wong, T.P.1    Debnam, E.S.2    Leung, P.S.3
  • 9
    • 0036146790 scopus 로고    scopus 로고
    • Immunohistochemical localization of angiotensin II receptor and local renin-angiotensin system in human colonic mucosa
    • Hirasawa K, Sato Y, Hosoda Y, et al. Immunohistochemical localization of angiotensin II receptor and local renineangiotensin system in human colonic mucosa. J Histochem Cytochem 2002;50:275-82. (Pubitemid 34106766)
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.2 , pp. 275-282
    • Hirasawa, K.1    Sato, Y.2    Hosoda, Y.3    Yamamoto, T.4    Hanai, H.5
  • 10
    • 0026549259 scopus 로고
    • Distribution of angiotensin II receptor subtypes in rat and human kidney
    • Sechi LA, Grady EF, Griffin CA, et al. Distribution of angiotensin II receptor subtypes in rat and human kidney. Am J Physiol 1992;262:F236-40.
    • (1992) Am J Physiol , vol.262
    • Sechi, L.A.1    Grady, E.F.2    Griffin, C.A.3
  • 11
    • 30144435593 scopus 로고    scopus 로고
    • Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis
    • DOI 10.1007/s10495-005-2138-y
    • Wildhaber BE, Yang H, Haxhija EQ. Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis. Apoptosis 2005;10:1305-15. (Pubitemid 43118372)
    • (2005) Apoptosis , vol.10 , Issue.6 , pp. 1305-1315
    • Wildhaber, B.E.1    Yang, H.2    Haxhija, E.Q.3    Spencer, A.U.4    Teitelbaum, D.H.5
  • 12
    • 51149121260 scopus 로고    scopus 로고
    • Modulation of mouse intestinal epithelial cell turnover in the absence of angiotensin converting enzyme
    • Haxhija EQ, Yang H, Spencer AU, et al. Modulation of mouse intestinal epithelial cell turnover in the absence of angiotensin converting enzyme. Am J Physiol Gastrointest Liver Physiol 2008;295:G88-98.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Haxhija, E.Q.1    Yang, H.2    Spencer, A.U.3
  • 13
    • 52449126670 scopus 로고    scopus 로고
    • Increased colonic sodium absorption in rats with chronic renal failure is partially mediated by AGTR1 receptor agonism
    • Hatch M, Freel RW. Increased colonic sodium absorption in rats with chronic renal failure is partially mediated by AGTR1 receptor agonism. Am J Physiol Gastrointest Liver Physiol 2008;295:G348-56.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Hatch, M.1    Freel, R.W.2
  • 15
    • 0031867992 scopus 로고    scopus 로고
    • Regulation of jejunal sodium and water absorption by angiotensin subtype receptors
    • Jin XH, Wang ZQ, Siragy HM, et al. Regulation of jejunal sodium and water absorption by angiotensin subtype receptors. Am J Physiol 1998;275:R515-23.
    • (1998) Am J Physiol , vol.275
    • Jin, X.H.1    Wang, Z.Q.2    Siragy, H.M.3
  • 16
    • 0021930191 scopus 로고
    • Control of intestinal absorption by the renineangiotensin system
    • Levens NR. Control of intestinal absorption by the renineangiotensin system. Am J Physiol 1985;249:G3-15.
    • (1985) Am J Physiol , vol.249
    • Levens, N.R.1
  • 17
    • 0023032906 scopus 로고
    • Response of isolated rat jejunum to angiotensin peptides
    • Levens NR. Response of isolated rat jejunum to angiotensin peptides. Am J Physiol 1986;251:G559-66.
    • (1986) Am J Physiol , vol.251
    • Levens, N.R.1
  • 19
    • 2942692046 scopus 로고    scopus 로고
    • The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion
    • Ewert S, Johansson B, Holm M, et al. The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion. BMC Physiol 2003;3:1.
    • (2003) BMC Physiol , vol.3 , pp. 1
    • Ewert, S.1    Johansson, B.2    Holm, M.3
  • 20
    • 33645083470 scopus 로고    scopus 로고
    • Dynamic expression of the angiotensin II type 2 receptor and duodenal mucosal alkaline secretion in the SpragueeDawley rat
    • Ewert S, Sjoberg T, Johansson B, et al. Dynamic expression of the angiotensin II type 2 receptor and duodenal mucosal alkaline secretion in the SpragueeDawley rat. Exp Physiol 2006;91:191-9.
    • (2006) Exp Physiol , vol.91 , pp. 191-199
    • Ewert, S.1    Sjoberg, T.2    Johansson, B.3
  • 21
    • 0034968002 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor-mediated duodenal mucosal alkaline secretion in the rat
    • Johansson B, Holm M, Ewert S, et al. Angiotensin II type 2 receptor-mediated duodenal mucosal alkaline secretion in the rat. Am J Physiol Gastrointest Liver Physiol 2001;280:G1254-60.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Johansson, B.1    Holm, M.2    Ewert, S.3
  • 22
    • 64649102554 scopus 로고    scopus 로고
    • Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells
    • Musch MW, Li YC, Chang EB. Angiotensin II directly regulates intestinal epithelial NHE3 in Caco2BBE cells. BMC Physiol 2009;9:5.
    • (2009) BMC Physiol , vol.9 , pp. 5
    • Musch, M.W.1    Li, Y.C.2    Chang, E.B.3
  • 23
    • 77950628016 scopus 로고    scopus 로고
    • Involvement of angiotensin II in intestinal cholesterol absorption
    • Nakamura K, Matsui T, Adachi H, et al. Involvement of angiotensin II in intestinal cholesterol absorption. Pharmacol Res 2010;61:460-5.
    • (2010) Pharmacol Res , vol.61 , pp. 460-465
    • Nakamura, K.1    Matsui, T.2    Adachi, H.3
  • 24
    • 67650097016 scopus 로고    scopus 로고
    • Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion
    • Barbolina MV, Adley BP, Kelly DL, et al. Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion. Int J Cancer 2009;125:816-25.
    • (2009) Int J Cancer , vol.125 , pp. 816-825
    • Barbolina, M.V.1    Adley, B.P.2    Kelly, D.L.3
  • 25
    • 19844383074 scopus 로고    scopus 로고
    • Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies
    • DOI 10.1093/carcin/bgi034
    • Tai IT, Dai M, Chen LB. Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies. Carcinogenesis 2005;26:908-15. (Pubitemid 41214319)
    • (2005) Carcinogenesis , vol.26 , Issue.5 , pp. 908-915
    • Tai, I.T.1    Dai, M.2    Chen, L.B.3
  • 26
    • 33644866797 scopus 로고    scopus 로고
    • Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
    • Tzima E. Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ Res 2006;98:176-85.
    • (2006) Circ Res , vol.98 , pp. 176-185
    • Tzima, E.1
  • 27
    • 0027189961 scopus 로고
    • The biochemical basis of the NADPH oxidase of phagocytes
    • DOI 10.1016/0968-0004(93)90051-N
    • Segal AW, Abo A. The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci 1993;18:43-7. (Pubitemid 23145110)
    • (1993) Trends in Biochemical Sciences , vol.18 , Issue.2 , pp. 43-47
    • Segal, A.W.1    Abo, A.2
  • 29
    • 0018699217 scopus 로고
    • Complete purification of dog renal renin
    • DOI 10.1021/bi00590a029
    • Dzau VJ, Slater EE, Haber E. Complete purification of dog renal renin. Biochemistry 1979;18:5224-8. (Pubitemid 10215981)
    • (1979) Biochemistry , vol.18 , Issue.23 , pp. 5224-5228
    • Dzau, V.J.1    Slater, E.E.2    Haber, E.3
  • 30
    • 0017697967 scopus 로고
    • Large scale purification of hog renin. Physicochemical characterization
    • Corvol P, Devaux C, Ito T, et al. Large scale purification of hog renin. Physicochemical characterization. Circ Res 1977;41:616-22. (Pubitemid 8216870)
    • (1977) Circulation Research , vol.41 , Issue.5 , pp. 616-622
    • Corvol, P.1    Devaux, C.2    Ito, T.3
  • 31
    • 0027301094 scopus 로고
    • Glycosylation of active human renin is necessary for secretion: Effect of targeted modifications of Asn-5 and Asn-75
    • Rothwell V, Kosowski S, Hadjilambris O, et al. Glycosylation of active human renin is necessary for secretion: effect of targeted modifications of Asn-5 and Asn-75. DNA Cell Biol 1993;12:291-8. (Pubitemid 23153162)
    • (1993) DNA and Cell Biology , vol.12 , Issue.4 , pp. 291-298
    • Rothwell, V.1    Kosowski, S.2    Hadjilambris, O.3    Baska, R.4    Norman, J.5
  • 32
    • 0024336222 scopus 로고
    • Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases
    • Maley F, Trimble RB, Tarentino AL, et al. Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases. Anal Biochem 1989;180:195-204. (Pubitemid 19198046)
    • (1989) Analytical Biochemistry , vol.180 , Issue.2 , pp. 195-204
    • Maley, F.1    Trimble, R.B.2    Tarentino, A.L.3    Plummer Jr., T.H.4
  • 34
    • 0018268698 scopus 로고
    • Circadian variation of blood-pressure
    • Millar-Craig MW, Bishop CN, et al. Circadian variation of blood-pressure. Lancet 1978;1:795-7.
    • (1978) Lancet , vol.1 , pp. 795-797
    • Millar-Craig, M.W.1    Bishop, C.N.2
  • 35
    • 0036900095 scopus 로고    scopus 로고
    • Augmented diurnal variations of the cardiac renin-angiotensin system in hypertensive rats
    • DOI 10.1161/01.HYP.0000039960.66987.89
    • Naito Y, Tsujino T, Fujioka Y, et al. Augmented diurnal variations of the cardiac renineangiotensin system in hypertensive rats. Hypertension 2002;40:827-33. (Pubitemid 35434902)
    • (2002) Hypertension , vol.40 , Issue.6 , pp. 827-833
    • Naito, Y.1    Tsujino, T.2    Fujioka, Y.3    Ohyanagi, M.4    Iwasaki, T.5
  • 37
    • 0021821541 scopus 로고
    • Nocturnal feeding in the mouse - opiate and pineal influences
    • DOI 10.1016/0024-3205(85)90393-5
    • Kavaliers M, Hirst M, Teskey GC. Nocturnal feeding in the mousedopiate and pineal influences. Life Sci 1985;36:973-80. (Pubitemid 15080855)
    • (1985) Life Sciences , vol.36 , Issue.10 , pp. 973-980
    • Kavaliers, M.1    Hirst, M.2    Teskey, G.C.3
  • 38
    • 50249187869 scopus 로고    scopus 로고
    • Circadian oscillation of hippocampal MAPK activity and cAmp: Implications for memory persistence
    • Eckel-Mahan KL, Phan T, Han S, et al. Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence. Nat Neurosci 2008;11:1074-82.
    • (2008) Nat Neurosci , vol.11 , pp. 1074-1082
    • Eckel-Mahan, K.L.1    Phan, T.2    Han, S.3
  • 39
    • 11244309604 scopus 로고    scopus 로고
    • Transcriptional regulation of renin: An update
    • DOI 10.1161/01.HYP.0000149717.55920.45
    • Pan L, Gross KW. Transcriptional regulation of renin: an update. Hypertension 2005;45:3-8. (Pubitemid 40066404)
    • (2005) Hypertension , vol.45 , Issue.1 , pp. 3-8
    • Pan, L.1    Gross, K.W.2
  • 40
    • 0035824520 scopus 로고    scopus 로고
    • Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression
    • Pan L, Black TA, Shi Q, et al. Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. J Biol Chem 2001;276:45530-8.
    • (2001) J Biol Chem , vol.276 , pp. 45530-45538
    • Pan, L.1    Black, T.A.2    Shi, Q.3
  • 41
    • 77953305755 scopus 로고    scopus 로고
    • LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain
    • Deguchi A, Miyoshi H, Kojima Y, et al. LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain. J Biol Chem 2010;285:18283-90.
    • (2010) J Biol Chem , vol.285 , pp. 18283-18290
    • Deguchi, A.1    Miyoshi, H.2    Kojima, Y.3
  • 42
    • 58649110598 scopus 로고    scopus 로고
    • Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
    • Zheng B, Jeong JH, Asara JM, et al. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 2009;33:237-47.
    • (2009) Mol Cell , vol.33 , pp. 237-247
    • Zheng, B.1    Jeong, J.H.2    Asara, J.M.3
  • 44
    • 34548097240 scopus 로고    scopus 로고
    • AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: Mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models
    • DOI 10.1158/1535-7163.MCT-07-0231
    • Davies BR, Logie A, McKay JS, et al. AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/ pharmacodynamic relationship, and potential for combination in preclinical models. Mol Cancer Ther 2007;6:2209-19. (Pubitemid 47294749)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.8 , pp. 2209-2219
    • Davies, B.R.1    Logie, A.2    McKay, J.S.3    Martin, P.4    Steele, S.5    Jenkins, R.6    Cockerill, M.7    Cartlidge, S.8    Smith, P.D.9
  • 45
    • 0031594573 scopus 로고    scopus 로고
    • New growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation
    • Xing J, Kornhauser JM, Xia Z, et al. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol Cell Biol 1998;18:1946-55. (Pubitemid 28152643)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.4 , pp. 1946-1955
    • Xing, J.1    Kornhauser, J.M.2    Xia, Z.3    Thiele, E.A.4    Greenberg, M.E.5
  • 46
    • 0022464749 scopus 로고
    • Angiotensin I converting enzyme in human intestine and kidney. Ultrastructural immunohistochemical localization
    • Bruneval P, Hinglais N, Alhenc-Gelas F, et al. Angiotensin I converting enzyme in human intestine and kidney. Ultrastructural immunohistochemical localization. Histochemistry 1986;85:73-80.
    • (1986) Histochemistry , vol.85 , pp. 73-80
    • Bruneval, P.1    Hinglais, N.2    Alhenc-Gelas, F.3
  • 47
    • 0026808767 scopus 로고
    • Angiotensin-converting enzyme of the human small intestine. Subunit and quaternary structure, biosynthesis and membrane association
    • Naim HY. Angiotensin-converting enzyme of the human small intestine. Subunit and quaternary structure, biosynthesis and membrane association. Biochem J 1992;286:451-7.
    • (1992) Biochem J , vol.286 , pp. 451-457
    • Naim, H.Y.1
  • 48
    • 0030014322 scopus 로고    scopus 로고
    • Secretion of human intestinal angiotensin-converting enzyme and its association with the differentiation state of intestinal cells
    • Naim HY. Secretion of human intestinal angiotensin-converting enzyme and its association with the differentiation state of intestinal cells. Biochem J 1996;316:259-64. (Pubitemid 26158230)
    • (1996) Biochemical Journal , vol.316 , Issue.1 , pp. 259-264
    • Naim, H.Y.1
  • 49
    • 0033015898 scopus 로고    scopus 로고
    • 1) expression in smooth muscle cells
    • Adams B, Obertone TS, Wang X, et al. Relationship between internalization and mRNA decay in down-regulation of recombinant type 1 angiotensin II receptor (AGTR1) expression in smooth muscle cells. Mol Pharmacol 1999;55:1028-36. (Pubitemid 29252368)
    • (1999) Molecular Pharmacology , vol.55 , Issue.6 , pp. 1028-1036
    • Adams, B.1    Obertone, T.S.2    Wang, X.3    Murphy, T.J.4
  • 50
    • 0036548754 scopus 로고    scopus 로고
    • Angiotensin II-mediated signal transduction pathways
    • Saito Y, Berk BC. Angiotensin II-mediated signal transduction pathways. Curr Hypertens Rep 2002;4:167-71.
    • (2002) Curr Hypertens Rep , vol.4 , pp. 167-171
    • Saito, Y.1    Berk, B.C.2
  • 51
    • 0042327752 scopus 로고    scopus 로고
    • Effects of mitogen-activated protein kinase pathway and co-activator CREP-binding protein on peroxisome proliferator-activated receptor-gamma- mediated transcription suppression of angiotensin II type 1 receptor gene
    • DOI 10.1291/hypres.26.623
    • Sugawara A, Takeuchi K, Uruno A, et al. Effects of mitogen-activated protein kinase pathway and co-activator CREP-binding protein on peroxisome proliferator-activated receptor-gamma-mediated transcription suppression of angiotensin II type 1 receptor gene. Hypertens Res 2003;26:623-8. (Pubitemid 37080795)
    • (2003) Hypertension Research , vol.26 , Issue.8 , pp. 623-628
    • Sugawara, A.1    Takeuchi, K.2    Uruno, A.3    Kudo, M.4    Sato, K.5    Ito, S.6
  • 52
    • 0028931708 scopus 로고
    • Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule
    • Cheng HF, Becker BN, Burns KD, et al. Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule. J Clin Invest 1995;95:2012-19.
    • (1995) J Clin Invest , vol.95 , pp. 2012-2019
    • Cheng, H.F.1    Becker, B.N.2    Burns, K.D.3
  • 53
    • 56649118939 scopus 로고    scopus 로고
    • The role of angiotensin II type 1a receptor on intestinal epithelial cells following small bowel
    • Koga H, Yang H, Haxhija EQ, et al. The role of angiotensin II type 1a receptor on intestinal epithelial cells following small bowel. Pediatr Surg Int 2008;24:1279-86.
    • (2008) Pediatr Surg Int , vol.24 , pp. 1279-1286
    • Koga, H.1    Yang, H.2    Haxhija, E.Q.3
  • 54
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build cryptevillus structures in vitro without a mesenchymal niche
    • Sato T, Vries RG, Snippert HJ, et al. Single Lgr5 stem cells build cryptevillus structures in vitro without a mesenchymal niche. Nature 2009;459:262-5.
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1    Vries, R.G.2    Snippert, H.J.3
  • 56
    • 20044370885 scopus 로고    scopus 로고
    • Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
    • DOI 10.1038/sj.emboj.7600667
    • Sakamoto K, McCarthy A, Smith D, et al. Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO J 2005;24:1810-20. (Pubitemid 40769500)
    • (2005) EMBO Journal , vol.24 , Issue.10 , pp. 1810-1820
    • Sakamoto, K.1    McCarthy, A.2    Smith, D.3    Green, K.A.4    Hardie, D.G.5    Ashworth, A.6    Alessi, D.R.7
  • 57
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain [1]
    • DOI 10.1038/5007
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999;21:70-1. (Pubitemid 29036285)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 60
    • 35748943872 scopus 로고    scopus 로고
    • Dialogue between LKB1 and AMPK: A hot topic at the cellular pole
    • Forcet C, Billaud M. Dialogue between LKB1 and AMPK: a hot topic at the cellular pole. Sci STKE 2007;404:pe51.
    • (2007) Sci STKE , vol.404
    • Forcet, C.1    Billaud, M.2
  • 61
    • 74249122511 scopus 로고    scopus 로고
    • LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells
    • Tamás P, Macintyre A, Finlay D, et al. LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells. Eur J Immunol 2010;40:242-53.
    • (2010) Eur J Immunol , vol.40 , pp. 242-253
    • Tamás, P.1    Macintyre, A.2    Finlay, D.3
  • 62
    • 70349324339 scopus 로고    scopus 로고
    • Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway
    • Shin SM, Cho IJ, Kim SG. Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway. Mol Pharmacol 2009;76:884-95.
    • (2009) Mol Pharmacol , vol.76 , pp. 884-895
    • Shin, S.M.1    Cho, I.J.2    Kim, S.G.3
  • 63
    • 0034733776 scopus 로고    scopus 로고
    • Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerotic factors
    • DOI 10.1016/S0167-0115(00)00105-1, PII S0167011500001051
    • Dimmeler S, Zeiher AM. Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerotic factors. Regul Pept 2000;90:19-25. (Pubitemid 30331005)
    • (2000) Regulatory Peptides , vol.90 , Issue.1-3 , pp. 19-25
    • Dimmeler, S.1    Zeiher, A.M.2
  • 65
    • 0025861543 scopus 로고
    • Rat angiotensin 11 receptor: cDNA sequence and regulation of the gene expression
    • Iwai NY, Yamano S, Chaki F, et al. Rat angiotensin 11 receptor: cDNA sequence and regulation of the gene expression. Biochem Biophys Res Commun 1991;177:299-304.
    • (1991) Biochem Biophys Res Commun , vol.177 , pp. 299-304
    • Iwai, N.Y.1    Yamano, S.2    Chaki, F.3
  • 66
    • 0026653005 scopus 로고
    • Two distinct pathways in the down-regulation of type-I angiotensin II receptor gene in rat glomerular mesangial cells
    • Makita NN, Iwai T, Inagami, et al. Two distinct pathways in the down-regulation of type-I angiotensin II receptor gene in rat glomerular mesangial cells. Biochem Biophys Res Commun 1992;185:142-6.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 142-146
    • Makita, N.N.1    Iwai, T.2    Inagami3
  • 67
    • 0026451051 scopus 로고
    • Differential regulation of rat AGTR1a and AGTR1b receptor mRNA
    • Iwai N, Inagami T, Ohmichi N, et al. Differential regulation of rat AGTR1a and AGTR1b receptor mRNA. Biochem Biophys Res Commun 1992;188:298-303.
    • (1992) Biochem Biophys Res Commun , vol.188 , pp. 298-303
    • Iwai, N.1    Inagami, T.2    Ohmichi, N.3
  • 68
    • 0026441234 scopus 로고
    • Differential gene expression and regulation of type-1 angiotensin II receptor subtypes in the rat
    • Kitami Y, Okura T, Marumoto K, et al. Differential gene expression and regulation of type-1 angiotensin II receptor subtypes in the rat. Biochem Biophys Res Commun 1992;188:446-52.
    • (1992) Biochem Biophys Res Commun , vol.188 , pp. 446-452
    • Kitami, Y.1    Okura, T.2    Marumoto, K.3
  • 69
    • 59149102643 scopus 로고    scopus 로고
    • Lkb1 is required for TGFbeta-mediated myofibroblast differentiation
    • Vaahtomeri K, Ventelä E, Laajanen K, et al. Lkb1 is required for TGFbeta-mediated myofibroblast differentiation. J Cell Sci 2008;121:3531-40.
    • (2008) J Cell Sci , vol.121 , pp. 3531-3540
    • Vaahtomeri, K.1    Ventelä, E.2    Laajanen, K.3
  • 71
    • 48249143587 scopus 로고    scopus 로고
    • LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment
    • Londesborough A, Vaahtomeri K, Tiainen M, et al. LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment. Development 2008;135:2331-8.
    • (2008) Development , vol.135 , pp. 2331-2338
    • Londesborough, A.1    Vaahtomeri, K.2    Tiainen, M.3
  • 73
    • 2142709556 scopus 로고    scopus 로고
    • Inducible Cre-Mediated Control of Gene Expression in the Murine Gastrointestinal Tract: Effect of Loss of beta-Catenin
    • DOI 10.1053/j.gastro.2004.03.020
    • Ireland H, Kemp R, Houghton C, et al. Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin. Gastroenterology 2004;126:1236-46 (Pubitemid 38552788)
    • (2004) Gastroenterology , vol.126 , Issue.5 , pp. 1236-1246
    • Ireland, H.1    Kemp, R.2    Houghton, C.3    Howard, L.4    Clarke, A.R.5    Sansom, O.J.6    Winton, D.J.7
  • 76
    • 0035710746 scopus 로고    scopus 로고
    • -DeltaDeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.