Erratum: LKb1 deficiency alters goblet and Paneth cell differentiation in the small intestine (PLoS ONE (2009) 4:1 (e4264) DOI:10.1371/journal.pone.0004264);Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine

PLoS ONE

Volumn 4, Issue 1, 2009, Pages

  Shorning, Boris Y ^a   Zabkiewicz, Joanna ^b   McCarthy, Afshan ^c   Pearson, Helen B ^d   Winton, Douglas J ^f   Sansom, Owen J ^e   Ashworth, Alan ^c   Clarke, Alan R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d PETER MACCALLUM CANCER CENTRE   (Australia)

^e BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^f IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA NAPHTHOFLAVONE; CRE RECOMBINASE; CYTOCHROME P450 1A1; NOTCH RECEPTOR; PROTEIN KINASE LKB1; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 5; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HES1 PROTEIN, MOUSE; HES5 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; STK11 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; EPITHELIUM CELL; GENE LOSS; GOBLET CELL; LOXP SITE; MOUSE; NONHUMAN; PANETH CELL; PROTEIN EXPRESSION; SECRETORY CELL; SIGNAL TRANSDUCTION; SMALL INTESTINE; ALLELE; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

MUS;

ALLELES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA-NAPHTHOFLAVONE; CELL DIFFERENTIATION; CYTOCHROME P-450 CYP1A1; GENE EXPRESSION REGULATION; GOBLET CELLS; HOMEODOMAIN PROTEINS; INTESTINE, SMALL; MICE; PANETH CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 59249096211     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0223041     Document Type: Erratum

References (34)

1. Tiainen M, Ylikorkala A, Makela TP (1999) Growth suppression by LKB1 is mediated by a G(1) cell cycle arrest. Proc Natl Acad Sci U S A 96: 9248-51.
2. Marignani PA, Kanai F, Carpenter CL (2001) LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest. J Biol Chem 276: 32415-8.
3. Hemminki A, Tomlinson I, Markie D, Järvinen H, Sistonen P, et al. (1997) Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 15(1): 87-90.
4. Yoo LI, Chung DC, Yuan J (2002) LKB1-a master tumour suppressor of the small intestine and beyond. Nat Rev Cancer 2: 529-35.
5. Tomlinson IP, Houlston RS (1997) Peutz-Jeghers syndrome. J Med Genet 34: 1007-11.
6. Katajisto P, Vaahtomeri K, Ekman N, Ventelä E, Ristimäki A, et al. (2008) LKB1 Signaling in Mesenchymal Cells Required for Suppression of Gastrointestinal Polyposis. Nature Genetics 40(4): 455-9.
7. Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, et al. (2003) Complexes between the Lkb1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2(4): 28.
8. Lizcano JM, Goransson O, Toth R, Deak M, Morrice NA, et al. (2004) Lkb1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 23(4): 833-43.
9. Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, et al. (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci U S A 101: 3329-35.
10. Mirouse V, Swick LL, Kazgan N, St Johnston D, Brenman JE (2007) LKB1 and AMPK maintain epithelial cell polarity under energetic stress. J Cell Biol 177(3): 387-92.
11. Sakamoto K, McCarthy A, Smith D, Green KA, Hardie DG (2005) Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO J 24(10): 1810-20.
12. Pearson HB, McCarthy A, Collins CMP, Ashworth A, Clarke AR (2008) Lkb1 Deficiency Causes Prostate Neoplasia in the Mouse. Cancer Research 68: 2223-2232.
13. Ireland H, Kemp R, Houghton C, Howard L, Clarke AR, et al. (2004) Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of β-catenin. Gastroenterology 126: 1236-46.
14. Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, et al. (2004) Loss of Apc in vivo immediately perturbs Wnt signalling, differentiation, and migration. Genes Dev 18: 1385-90.
15. Rowan A, Churchman M, Jefferey R, Hanby A, Poulsom R, Tomlinson I (2000) In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours. J Pathol 192: 203-206.
16. Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21: 70-1.
17. Kemp R, Ireland H, Clayton E, Houghton C, Howard L, Winton DJ (2004) Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity. Nucleic Acids Res 32(11): e92.
18. Troughton WD, Trier JS (1969) Paneth and goblet cell renewal in mouse duodenal crypts. J Cell Biol 41(1): 251-68.
19. Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, et al. (2000) Control of endodermal endocrine development by Hes-1. Nature Genet 24: 36-44.
20. Zecchini V, Domaschenz R, Winton D, Jones P (2005) Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells. Genes Dev 19: 1686-91.
21. Bayraktar J, Zygmunt D, Carthew RW (2006) Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo. J Cell Sci 119(Pt 4): 711-21.
22. Fingar DC, Salama S, Tsou C, Harlow E, Blenis J (2002) Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/ eIF4E. Genes and Development 16: 1472-1487.
23. Wang ZJ, Ellis I, Zauber P, Iwama T, Marchese C, et al. (1999) Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence. J Pathol 188: 9-13.
24. Satoh Y, Yamano M, Matsuda M, Ono K (1990) Ultrastructure of Paneth cells in the intestine of various mammals. Journal of Electron Microscopy Technique 16: 69-80.
25. Spicer SS, Staley MW, Wetzel MG, Wetzel BK (1967) Acid mucosubstance and basic protein in mouse Paneth cells. J Histochem Cytochem 15: 225-242.
26. Selzman HM, Liebelt RA (1962) Paneth cell granule of mouse intestine. J Cell Biol. pp 15136-139.
27. van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, et al. (2005) Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435: 959-63.
28. Crosnier C, Vargesson N, Gschmeissner S, Ariza-McNaughton L, Morrison A, Lewis J (2005) Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development 132(5): 1093-104.
29. Ohlstein O, Spradling A (2007) Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential Notch signaling. Science 315: 988-992.
30. Sapir A, Assa-Kunik E, Tsruya R, Schejter E, Shilo BZ (2005) Unidirectional Notch signaling depends on continuous cleavage of Delta. Development 132(1): 123-32.
31. Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S (2005) Notch signals control the fate of immature progenitor cells in the intestine. Nature 435: 964-8.
32. Garabedian EM, Roberts LJ, McNevin MS, Gordon JI (1997) J Biol Chem 272: 23729-23740.
33. Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC (2004) Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 116: 457-66.
34. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-8.