Deranged bioenergetics and defective redox capacity in T lymphocytes and neutrophils are related to cellular dysfunction and increased oxidative stress in patients with active systemic lupus erythematosus

Clinical and Developmental Immunology

Volumn 2012, Issue , 2012, Pages

  Li, Ko Jen ^a,b   Wu, Cheng Han ^a   Hsieh, Song Chou ^a   Lu, Ming Chi ^c   Tsai, Chang Youh ^d   Yu, Chia Li ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE TRIPHOSPHATE; AMINO ACID DERIVATIVE; AZATHIOPRINE; CD53 ANTIGEN; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 6; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROXYCHLOROQUINE; LACTIC ACID; N BENZOYLGLYCYL N EPSILON(HEXANOYL)LYSINE; PREDNISOLONE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DRUG DERIVATIVE; LYSINE; SLC2A9 PROTEIN, HUMAN;

ADULT; ARTICLE; BIOENERGY; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE DURATION; ENZYME ACTIVITY; FATTY ACID OXIDATION; FEMALE; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; URINARY EXCRETION; ADOLESCENT; BRAIN VASCULITIS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; PATHOPHYSIOLOGY; URINE;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; ENERGY METABOLISM; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLUCOSE TRANSPORTER TYPE 3; GLUTATHIONE PEROXIDASE; HUMANS; LUPUS VASCULITIS, CENTRAL NERVOUS SYSTEM; LYSINE; MALE; NEUTROPHILS; OXIDATION-REDUCTION; OXIDATIVE STRESS; T-LYMPHOCYTES;

EID: 84855181178     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2012/548516     Document Type: Article

References (49)

1. Avalos I., Chung C. P., Oeser A., Milne G. L., Morrow J. D., Gebretsadik T., Shintani A., Yu C., Stein C. M., Oxidative stress in systemic lupus erythematosus: relationship to disease activity and symptoms Lupus 2007 16 3 195 200 (Pubitemid 46506597)
2. Wang G., Pierangeli S. S., Papalardo E., Ansari G. A. S., Khan M. F., Markers of oxidative and nitrosative stress in systemic lupus erythematosus Arthritis and Rheumatism 2010 62 7 2064 2072
3. Gergely P., Grossman C., Niland B., Puskas F., Neupane H., Allam F., Banki K., Phillips P. E., Perl A., Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus Arthritis and Rheumatism 2002 46 1 175 190 (Pubitemid 34121663)
4. Kurien B. T., Scofield R. H., Free radical mediated peroxidative damage in systemic lupus erythematosus Life Sciences 2003 73 13 1655 1666 (Pubitemid 36869006)
5. Buttgereit F., Burmester G. R., Brand M. D., Bioenergetics of immune functions: fundamental and therapeutic aspects Immunology Today 2000 21 4 192 199 (Pubitemid 30184792)
6. Krauss S., Brand M. D., Buttgereit F., Signaling takes a breathNew quantitative perspectives on bioenergetics and signal transduction Immunity 2001 15 4 497 502 (Pubitemid 33016435)
7. Van Schaftingen E., Gerin I., The glucose-6-phosphatase system Biochemical Journal 2002 362 3 513 532 (Pubitemid 34242301)
8. Bell G. I., Kayano T., Buse J. B., Burant C. F., Takeda J., Lin D., Fukumoto H., Seino S., Molecular biology of mammalian glucose transporters Diabetes Care 1990 13 3 198 208 (Pubitemid 20092107)
9. Burant C. F., Bell G. I., Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins Biochemistry 1992 31 42 10414 10420
10. Fukumoto H., Seino S., Imura H., Seino Y., Bell G. I., Characterization and expression of human HepG2/erythrocyte glucose-transporter gene Diabetes 1988 37 5 657 661
11. Estrada D. E., Elliott E., Zinman B., Poon I., Liu Z., Klip A., Daneman D., Regulation of glucose transport and expression of GLUT3 transporters in human circulating mononuclear cells: studies in cells from insulin-dependent diabetic and nondiabetic individuals Metabolism 1994 43 5 591 598 (Pubitemid 24145466)
12. Joost H. G., Thorens B., The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members Molecular Membrane Biology 2001 18 4 247 256 (Pubitemid 34052684)
13. Fu Y., Maianu L., Melbert B. R., Garvey W. T., Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation Blood Cells, Molecules, and Diseases 2004 32 1 182 190 (Pubitemid 38147716)
14. Viora M., Quaranta M. G., Straface E., Vari R., Masella R., Malorni W., Redox imbalance and immune functions: opposite effects of oxidized low-density lipoproteins and N -acetylcysteine Immunology 2001 104 4 431 438 (Pubitemid 34037836)
15. Holmgren A., Thioredoxin and glutaredoxin systems Journal of Biological Chemistry 1989 264 24 13963 13966 (Pubitemid 19214215)
16. Holmgren A., Glutathione-dependent synthesis of deoxyribonucleotides. Characterization of the enzymatic mechanism of Escherichia coli glutaredoxin Journal of Biological Chemistry 1979 254 9 3672 3678
17. Sen C. K., Nutritional biochemistry of cellular glutathione Journal of Nutritional Biochemistry 1997 8 12 660 672 (Pubitemid 29267949)
18. Carlisle M. L., King M. R., Karp D. R., -Glutamyl transpeptidase activity alters the T cell response to oxidative stress and Fas-induced apoptosis International Immunology 2003 15 1 17 27 (Pubitemid 36163765)
19. Pedersen-Lane J. H., Zurier R. B., Lawrence D. A., Analysis of the thiol status of peripheral blood leukocytes in rheumatoid arthritis patients Journal of Leukocyte Biology 2007 81 4 934 941 (Pubitemid 46495642)
20. Gladman D. D., Ibanez D., Urowitz M. B., Systemic lupus erythematosus disease activity index 2000 Journal of Rheumatology 2007 29 2 288 291
21. Li K. J., Lu M. C., Hsieh S. C., Wu C. H., Yu H. S., Tsai C. Y., Yu C. L., Release of surface-expressed lactoferrin from polymorphonuclear neutrophils after contact with CD4+T cells and its modulation on Th1/Th2 cytokine production Journal of Leukocyte Biology 2006 80 2 350 358
22. Frauwirth K. A., Riley J. L., Harris M. H., Parry R. V., Rathmell J. C., Plas D. R., Elstrom R. L., June C. H., Thompson C. B., The CD28 signaling pathway regulates glucose metabolism Immunity 2002 16 6 769 777 (Pubitemid 34786476)
23. Shikhman A. R., Brinson D. C., Valbracht J., Lotz M. K., Cytokine regulation of facilitated glucose transport in human articular chondrocytes Journal of Immunology 2001 167 12 7001 7008 (Pubitemid 33144195)
24. Kato Y., Mori Y., Makino Y., Morimitsu Y., Hiroi S., Ishikawa T., Osawa T., Formation of N()-(hexanonyl)lysine in protein exposed to lipid hydroperoxide. A plausible marker for lipid hydroperoxide Journal of Biological Chemistry 1999 274 29 20406 20414
25. Loft S., Fischer-Nielsen A., Jeding I. B., Vistisen K., Enghusen Poulsen H., 8-Hydroxydeoxyguanosine as a urinary biomarker of oxidative DNA damage Journal of Toxicology and Environmental Health 1993 40 2-3 391 404 (Pubitemid 23344366)
26. Tsokos G. C., Liossis S. N. C., Immune cell signaling defects in lupus: activation, anergy and death Immunology Today 1999 20 3 119 124 (Pubitemid 29130340)
27. Greiner E. F., Guppy M., Brand K., Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production Journal of Biological Chemistry 1994 269 50 31484 31490 (Pubitemid 24379505)
28. Frauwirth K. A., Thompson C. B., Regulation of T lymphocyte metabolism Journal of Immunology 2004 172 8 4661 4665 (Pubitemid 38456383)
29. Maciver N. J., Jacobs S. R., Wieman H. L., Wofford J. A., Coloff J. L., Rathmell J. C., Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival Journal of Leukocyte Biology 2008 84 4 949 957
30. Misso N. L. A., Peroni D. J., Neil Watkins D., Stewart G. A., Thompson P. J., Glutathione peroxidase activity and mRNA expression in eosinophils and neutrophils of asthmatic and non-asthmatic subjects Journal of Leukocyte Biology 1998 63 1 124 130 (Pubitemid 28070391)
31. Morgan P. E., Sturgess A. D., Davies M. J., Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus Arthritis and Rheumatism 2005 52 7 2069 2079 (Pubitemid 41001420)
32. Shah D., Kiran R., Wanchu A., Bhatnagar A., Oxidative stress in systemic lupus erythematosus: relationship to Th1 cytokine and disease activity Immunology Letters 2010 129 1 7 12
33. Tan A. S., Ahmed N., Berridge M. V., Acute regulation of glucose transport after activation of human peripheral blood neutrophils by phorbol myristate acetate, fMLP, and granulocyte-macrophage colony-stimulating factor Blood 1998 91 2 649 655 (Pubitemid 28053390)
34. Schuster D. P., Brody S. L., Zhou Z., Bernstein M., Arch R., Link D., Mueckler M., Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake American Journal of Physiology 2007 292 4 L845 L851
35. Fox C. J., Hammerman P. S., Thompson C. B., Fuel feeds function: energy metabolism and the T-cell response Nature Reviews Immunology 2005 5 11 844 852 (Pubitemid 41581666)
36. Hsieh S. C., Sun K. H., Tsai C. Y., Tsai Y. Y., Tsai S. T., Huang D. F., Han S. H., Yu H. S., Yu C. L., Monoclonal anti-double stranded DNA antibody is a leucocyte-binding protein to up-regulate interleukin-8 gene expression and elicit apoptosis of normal human polymorphonuclear neutrophils Rheumatology 2001 40 8 851 858
37. Hsieh S. C., Yu H. S., Lin W. W., Sun K. H., Tsai C. Y., Huang D. F., Tsai Y. Y., Yu C. L., Anti-SSB/La is one of the antineutrophil autoantibodies responsible for neutropenia and functional impairment of polymorphonuclear neutrophils in patients with systemic lupus erythematosus Clinical and Experimental Immunology 2003 131 3 506 516
38. Garcia-Welsh A., Schneiderman J. S., Baly D. L., Interleukin-1 stimulates glucose transport in rat adipose cells. Evidence for receptor discrimination between IL-1 and IL-1 FEBS Letters 1990 269 2 421 424 (Pubitemid 20273839)
39. Hernvann A., Aussel C., Cynober L., Moatti N., Ekindjian O. G., IL-1, a strong mediator for glucose uptake by rheumatoid and non-rheumatoid cultured human synoviocytes FEBS Letters 1992 303 1 77 80
40. Bedard S., Marcotte B., Marette A., Cytokines modulate glucose transport in skeletal muscle by inducing the expression of inducible nitric oxide synthase Biochemical Journal 1997 325 2 487 493 (Pubitemid 27338732)
41. Kim T., Kanayama Y., Negoro N., Okamura M., Takeda T., Inoue T., Serum levels of interferons in patients with systemic lupus erythematosus Clinical and Experimental Immunology 1987 70 3 562 569 (Pubitemid 18013195)
42. Grondal G., Gunnarsson I., Ronnelid J., Rogberg S., Klareskog L., Lundberg I., Cytokine production, serum levels and disease activity in systemic lupus erythematosus Clinical and Experimental Rheumatology 2000 18 5 565 570
43. Sabry A., sheashaa H., El-husseini A., Mahmoud K., Eldahshan K. F., George S. K., Abdel-Khalek E., El-Shafey E. M., Abo-Zenah H., Proinflammatory cytokines (TNF- and IL-6) in Egyptian patients with SLE: its correlation with disease activity Cytokine 2006 35 3-4 148 153 (Pubitemid 44666430)
44. Maurice M. M., Nakamura H., Van Der Voort E. A. M., Van Vliet A. I., Staal F. J. T., Tak P. P., Breedveld F. C., Verweij C. L., Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis Journal of Immunology 1997 158 3 1458 1465 (Pubitemid 127469974)
45. Bazzichi L., Ciompi M. L., Betti L., Rossi A., Melchiorre D., Fiorini M., Giannaccini G., Lucacchini A., Impaired gluthathione reductase activity and levels of collagenase and elastase in synovial fluid in rheumatoid arthritis Clinical and Experimental Rheumatology 2002 20 6 761 766 (Pubitemid 35446965)
46. Porter M., Pearson D. J., Suarez-Mendez V. J., Blann A. D., Plasma, platelet and erythrocyte glutathione peroxidases as risk factors in ischaemic heart disease in man Clinical Science 1992 83 3 343 345
47. Ishibashi N., Prokopenko O., Reuhl K. R., Mirochnitchenko O., Inflammatory response and glutathione peroxidase in a model of stroke Journal of Immunology 2002 168 4 1926 1933 (Pubitemid 34135795)
48. Comhair S. A. A., Bhathena P. R., Farver C., Thunnissen F. B. J. M., Erzurum S. C., Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells FASEB Journal 2001 15 1 70 78 (Pubitemid 32061657)
49. Wahl D. R., Petersen B., Warner R., Richardson B. C., Glick G. D., Opipari A. W., Characterization of the metabolic phenotype of chronically activated lymphocytes Lupus 2010 19 13 1492 1501