메뉴 건너뛰기




Volumn 13, Issue 1, 2011, Pages

On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure

Author keywords

[No Author keywords available]

Indexed keywords

DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; IRON CHELATING AGENT;

EID: 84855169923     PISSN: 10976647     EISSN: 1532429X     Source Type: Journal    
DOI: 10.1186/1532-429X-13-45     Document Type: Article
Times cited : (49)

References (82)
  • 4
    • 58149216075 scopus 로고    scopus 로고
    • T2* cardiovascular magnetic resonance in the management of thalassemia patients in Oman
    • 10.3324/haematol.13845 19001285
    • T2* cardiovascular magnetic resonance in the management of thalassemia patients in Oman. Daar S, Pathare AV, Jain R, Zadjali SA, Pennell DJ, Haematologica 2009 94 140 1 10.3324/haematol.13845 19001285
    • (2009) Haematologica , vol.94 , pp. 140-141
    • Daar, S.1    Pathare, A.V.2    Jain, R.3    Zadjali, S.A.4    Pennell, D.J.5
  • 6
    • 77958543057 scopus 로고    scopus 로고
    • Cardiac magnetic resonance in transfusion dependent thalassaemia: Assessment of iron load and relationship to left ventricular ejection fraction
    • 10.1111/j.1365-2141.2010.08365.x 20813008
    • Cardiac magnetic resonance in transfusion dependent thalassaemia: assessment of iron load and relationship to left ventricular ejection fraction. Chouliaras GL, Kattamis A, Berdoukas V, Gotsis ED, Mavrogeni S, Ladis V, Br J Haematol 2010 151 397 401 10.1111/j.1365-2141.2010.08365.x 20813008
    • (2010) Br J Haematol , vol.151 , pp. 397-401
    • Chouliaras, G.L.1    Kattamis, A.2    Berdoukas, V.3    Gotsis, E.D.4    Mavrogeni, S.5    Ladis, V.6
  • 9
    • 34247103036 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance
    • DOI 10.1161/CIRCULATIONAHA.106.648790
    • A randomized, placebo controlled, double blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance. Tanner MA, Galanello R, Dessi C, Smith GC, Westwood MA, Agus A, Roughton M, Assomull R, Nair SV, Walker JM, Pennell DJ, Circulation 2007 115 1876 84 10.1161/CIRCULATIONAHA.106. 648790 17372174 (Pubitemid 46598901)
    • (2007) Circulation , vol.115 , Issue.14 , pp. 1876-1884
    • Tanner, M.A.1    Galanello, R.2    Dessi, C.3    Smith, G.C.4    Westwood, M.A.5    Agus, A.6    Roughton, M.7    Assomull, R.8    Nair, S.V.9    Walker, J.M.10    Pennell, D.J.11
  • 12
    • 70349567584 scopus 로고    scopus 로고
    • The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: A clinical observational study
    • 10.1186/1532-429X-11-20 19558722
    • The efficacy of iron chelator regimes in reducing cardiac and hepatic iron in patients with thalassaemia major: a clinical observational study. Berdoukas V, Chouliaras G, Moraitis P, Zannikos P, Berdoussi E, Ladis V, J Cardiovasc Magn Reson 2009 11 20 10.1186/1532-429X-11-20 19558722
    • (2009) J Cardiovasc Magn Reson , vol.11 , pp. 20
    • Berdoukas, V.1    Chouliaras, G.2    Moraitis, P.3    Zannikos, P.4    Berdoussi, E.5    Ladis, V.6
  • 14
    • 57349095277 scopus 로고    scopus 로고
    • Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance
    • 10.1186/1532-429X-10-42 18817553
    • Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance. Modell B, Khan M, Darlison M, Westwood MA, Ingram D, Pennell DJ, J Cardiovasc Magn Reson 2008 10 42 10.1186/1532-429X-10-42 18817553
    • (2008) J Cardiovasc Magn Reson , vol.10 , pp. 42
    • Modell, B.1    Khan, M.2    Darlison, M.3    Westwood, M.A.4    Ingram, D.5    Pennell, D.J.6
  • 15
    • 73149099158 scopus 로고    scopus 로고
    • Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone
    • 10.3324/haematol.2009.009118 19815834
    • Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone. Telfer PT, Warburton F, Christou S, Hadjigavriel M, Sitarou M, Kolnagou A, Angastiniotis M, Haematologica 2009 94 1777 8 10.3324/haematol.2009. 009118 19815834
    • (2009) Haematologica , vol.94 , pp. 1777-1778
    • Telfer, P.T.1    Warburton, F.2    Christou, S.3    Hadjigavriel, M.4    Sitarou, M.5    Kolnagou, A.6    Angastiniotis, M.7
  • 16
    • 7944230624 scopus 로고    scopus 로고
    • Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: A prospective study using T2* cardiovascular magnetic resonance
    • DOI 10.1111/j.1365-2141.2004.05202.x
    • Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance. Anderson LJ, Westwood MA, Holden S, Davis B, Prescott E, Wonke B, Porter JB, Walker JM, Pennell DJ, Br J Haematol 2004 127 348 55 10.1111/j.1365-2141.2004.05202.x 15491298 (Pubitemid 39468951)
    • (2004) British Journal of Haematology , vol.127 , Issue.3 , pp. 348-355
    • Anderson, L.J.1    Westwood, M.A.2    Holden, S.3    Davis, B.4    Prescott, E.5    Wonke, B.6    Porter, J.B.7    Walker, J.M.8    Pennell, D.J.9
  • 17
    • 0035478793 scopus 로고    scopus 로고
    • Hemoglobinopathies: An opportunity to study cardiac disease
    • DOI 10.1016/S0002-9343(01)00943-3, PII S0002934301009433
    • Heart failure in beta thalassemia: a 5-year follow-up study. Kremastinos DT, Tsetsos GA, Tsiapras DP, Karavolias GK, Ladis VA, Kattamis CA, Am J Med 2001 111 407 8 10.1016/S0002-9343(01)00943-3 11583647 (Pubitemid 32913677)
    • (2001) American Journal of Medicine , vol.111 , Issue.5 , pp. 407-408
    • Manno, C.S.1    Jessup, M.2
  • 21
    • 33745889016 scopus 로고    scopus 로고
    • Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance
    • 10.1080/10976640600572889 16755827
    • Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. Maceira AM, Prasad SK, Khan M, Pennell DJ, J Cardiovasc Magn Reson 2006 8 417 26 10.1080/ 10976640600572889 16755827
    • (2006) J Cardiovasc Magn Reson , vol.8 , pp. 417-426
    • MacEira, A.M.1    Prasad, S.K.2    Khan, M.3    Pennell, D.J.4
  • 22
    • 0036642629 scopus 로고    scopus 로고
    • Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy
    • DOI 10.1016/S0002-9149(02)02381-0, PII S0002914902023810
    • Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy. Grothues F, Smith GC, Moon JCC, Bellenger NG, Collins P, Klein H, Pennell DJ, Am J Cardiol 2002 90 29 34 10.1016/S0002-9149(02)02381-0 12088775 (Pubitemid 34671198)
    • (2002) American Journal of Cardiology , vol.90 , Issue.1 , pp. 29-34
    • Grothues, F.1    Smith, G.C.2    Moon, J.C.C.3    Bellenger, N.G.4    Collins, P.5    Klein, H.U.6    Pennell, D.J.7
  • 24
    • 0038187626 scopus 로고    scopus 로고
    • Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis
    • Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis. Piga A, Gaglioti C, Fogliacco E, Tricta F, Haematologica 2003 88 489 96 12745268 (Pubitemid 36648438)
    • (2003) Haematologica , vol.88 , Issue.5 , pp. 489-496
    • Piga, A.1    Gaglioti, C.2    Fogliacco, E.3    Tricta, F.4
  • 27
    • 73149099158 scopus 로고    scopus 로고
    • Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone
    • 10.3324/haematol.2009.009118 19815834
    • Improved survival in thalassemia major patients on switching from desferrioxamine to combined chelation therapy with desferrioxamine and deferiprone. Telfer PT, Warburton F, Christou S, Hadjigavriel M, Sitarou M, Kolnagou A, Angastiniotis M, Haematologica 2009 94 1777 8 10.3324/haematol.2009. 009118 19815834
    • (2009) Haematologica , vol.94 , pp. 1777-1778
    • Telfer, P.T.1    Warburton, F.2    Christou, S.3    Hadjigavriel, M.4    Sitarou, M.5    Kolnagou, A.6    Angastiniotis, M.7
  • 29
    • 0037125595 scopus 로고    scopus 로고
    • Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
    • DOI 10.1016/S0140-6736(02)09740-4
    • Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ, Lancet 2002 360 516 20 10.1016/S0140-6736(02)09740-4 12241655 (Pubitemid 35232104)
    • (2002) Lancet , vol.360 , Issue.9332 , pp. 516-520
    • Anderson, L.J.1    Wonke, B.2    Prescott, E.3    Holden, S.4    Walker, J.M.5    Pennell, D.J.6
  • 30
    • 3042746877 scopus 로고    scopus 로고
    • Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major
    • DOI 10.1182/blood-2003-08-2841
    • Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major. Davis BA, O'Sullivan C, Jarritt PH, Porter JB, Blood 2004 104 263 9 10.1182/blood-2003-08-2841 15001468 (Pubitemid 38879867)
    • (2004) Blood , vol.104 , Issue.1 , pp. 263-269
    • Davis, B.A.1    O'Sullivan, C.2    Jarritt, P.H.3    Porter, J.B.4
  • 31
    • 0033879659 scopus 로고    scopus 로고
    • Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance. Are they interchangeable?
    • DOI 10.1053/euhj.2000.2011
    • Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance Are they interchangeable? Bellenger NG, Burgess MI, Ray SG, Lahiri A, Coats AJ, Pennell DJ, CHRISTMAS Study Steering Committee and Investigators, Eur Heart J 2000 21 1387 96 10.1053/euhj.2000.2011 10952828 (Pubitemid 30599134)
    • (2000) European Heart Journal , vol.21 , Issue.16 , pp. 1387-1396
    • Bellenger, N.G.1    Burgess, M.I.2    Ray, S.G.3    Lahiri, A.4    Coats, A.J.S.5    Cleland, J.G.F.6    Pennell, D.J.7
  • 34
    • 84988044805 scopus 로고    scopus 로고
    • The energetics of genome complexity
    • 10.1038/nature09486 20962839
    • The energetics of genome complexity. Lane N, Martin W, Nature 2010 467 929 34 10.1038/nature09486 20962839
    • (2010) Nature , vol.467 , pp. 929-934
    • Lane, N.1    Martin, W.2
  • 35
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • DOI 10.1152/physrev.00006.2004
    • Myocardial substrate metabolism in the normal and failing heart. Stanley WC, Recchia FA, Lopaschuk GD, Physiol Rev 2005 85 1093 129 10.1152/physrev. 00006.2004 15987803 (Pubitemid 40894649)
    • (2005) Physiological Reviews , vol.85 , Issue.3 , pp. 1093-1129
    • Stanley, W.C.1    Recchia, F.A.2    Lopaschuk, G.D.3
  • 36
    • 0141634243 scopus 로고    scopus 로고
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles
    • DOI 10.1113/jphysiol.2003.045104
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles. Garnier A, Fortin D, Delomenie C, Momken I, Veksler V, Ventura-Clapier R, J Physiol 2003 551 491 501 10.1113/jphysiol.2003.045104 12824444 (Pubitemid 37121707)
    • (2003) Journal of Physiology , vol.551 , Issue.2 , pp. 491-501
    • Garnier, A.1    Fortin, D.2    Delomenie, C.3    Momken, I.4    Veksler, V.5    Ventura-Clapier, R.6
  • 37
    • 0027074115 scopus 로고
    • Energy status of the rapidly paced canine myocardium in congestive heart failure
    • Energy status of the rapidly paced canine myocardium in congestive heart failure. Montgomery C, Hamilton N, Ianuzzo CD, J Appl Physiol 1992 73 2363 7 1490944 (Pubitemid 23019640)
    • (1992) Journal of Applied Physiology , vol.73 , Issue.6 , pp. 2363-2367
    • Montgomery, C.1    Hamilton, N.2    Ianuzzo, C.D.3
  • 38
    • 0026615221 scopus 로고
    • 31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure
    • 1451253
    • 31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure. Neubauer S, Krahe T, Schindler R, Horn M, Hillenbrand H, Entzeroth C, et al. Circulation 1992 86 1810 8 1451253
    • (1992) Circulation , vol.86 , pp. 1810-1818
    • Neubauer, S.1    Krahe, T.2    Schindler, R.3    Horn, M.4    Hillenbrand, H.5    Entzeroth, C.6
  • 40
    • 34548394568 scopus 로고    scopus 로고
    • Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation
    • DOI 10.1152/ajpheart.00242.2007
    • Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation. Feygin J, Mansoor A, Eckman P, Swingen C, Zhang J, Am J Physiol Heart Circ Physiol 2007 293 1772 80 10.1152/ajpheart.00242.2007 17573463 (Pubitemid 47367227)
    • (2007) American Journal of Physiology - Heart and Circulatory Physiology , vol.293 , Issue.3
    • Feygin, J.1    Mansoor, A.2    Eckman, P.3    Swingen, C.4    Zhang, J.5
  • 41
    • 0030010439 scopus 로고    scopus 로고
    • Decreased energy reserve in an animal model of dilated cardiomyopathy: Relationship to contractile performance
    • Decreased energy reserve in an animal model of dilated cardiomyopathy. Relationship to contractile performance. Liao R, Nascimben L, Friedrich J, Gwathmey JK, Ingwall JS, Circ Res 1996 78 893 902 8620610 (Pubitemid 26131374)
    • (1996) Circulation Research , vol.78 , Issue.5 , pp. 893-902
    • Liao, R.1    Nascimben, L.2    Friedrich, J.3    Gwathmey, J.K.4    Ingwall, J.S.5
  • 44
    • 0032078224 scopus 로고    scopus 로고
    • Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells
    • Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells. Link G, Saada A, Pinson A, Konijn AM, Hershko C, J Lab Clin Med 1998 131 466 74 10.1016/S0022-2143(98)90148-2 9605112 (Pubitemid 28259763)
    • (1998) Journal of Laboratory and Clinical Medicine , vol.131 , Issue.5 , pp. 466-474
    • Link, G.1    Saada, A.2    Pinson, A.3    Konijn, A.M.4    Hershko, C.5
  • 46
    • 0033543124 scopus 로고    scopus 로고
    • Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: Implications for the arrhythmogenesis of human siderotic heart disease
    • Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes implications for the arrhythmogenesis of human siderotic heart disease. Kuryshev YA, Brittenham GM, Fujioka H, Kannan P, Shieh CC, Cohen SA, Brown AM, Circulation 1999 100 675 83 10441107 (Pubitemid 29379759)
    • (1999) Circulation , vol.100 , Issue.6 , pp. 675-683
    • Kuryshev, Y.A.1    Brittenham, G.M.2    Fujioka, H.3    Kannan, P.4    Shieh, C.-C.5    Cohen, S.A.6    Brown, A.M.7
  • 48
    • 0034960785 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiac disease: Ischemia - reperfusion, aging, and heart failure
    • DOI 10.1006/jmcc.2001.1378
    • Mitochondrial dysfunction in cardiac disease: ischemia - reperfusion, aging, and heart failure. Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL, J Mol Cell Cardiol 2001 33 1065 89 10.1006/jmcc.2001.1378 11444914 (Pubitemid 32579276)
    • (2001) Journal of Molecular and Cellular Cardiology , vol.33 , Issue.6 , pp. 1065-1089
    • Lesnefsky, E.J.1    Moghaddas, S.2    Tandler, B.3    Kerner, J.4    Hoppel, C.L.5
  • 49
    • 0032078224 scopus 로고    scopus 로고
    • Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells
    • Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells. Link G, Saada A, Pinson A, Konijn AM, Hershko C, J Lab Clin Med 1998 131 466 74 10.1016/S0022-2143(98)90148-2 9605112 (Pubitemid 28259763)
    • (1998) Journal of Laboratory and Clinical Medicine , vol.131 , Issue.5 , pp. 466-474
    • Link, G.1    Saada, A.2    Pinson, A.3    Konijn, A.M.4    Hershko, C.5
  • 50
    • 0011017415 scopus 로고    scopus 로고
    • Kluwer Academic Publishers. Norwell, Massachusetts, USA ISBN 1-4020-7093-4
    • ATP and the heart. Ingwall JS, Kluwer Academic Publishers. Norwell, Massachusetts, USA 2002 16 ISBN 1-4020-7093-4
    • (2002) ATP and the Heart , pp. 16
    • Ingwall, J.S.1
  • 51
    • 33947239659 scopus 로고    scopus 로고
    • The failing heart - An engine out of fuel
    • DOI 10.1056/NEJMra063052
    • The failing heart-an engine out of fuel. Neubauer S, N Engl J Med 2007 356 1140 51 10.1056/NEJMra063052 17360992 (Pubitemid 46425598)
    • (2007) New England Journal of Medicine , vol.356 , Issue.11 , pp. 1140-1151
    • Neubauer, S.1
  • 53
    • 0036569986 scopus 로고    scopus 로고
    • Molecular bases of cellular iron toxicity
    • DOI 10.1016/S0891-5849(02)00772-4, PII S0891584902007724
    • Molecular bases of cellular iron toxicity. Eaton JW, Qian M, Free Radic Biol Med 2002 32 833 40 10.1016/S0891-5849(02)00772-4 11978485 (Pubitemid 34439254)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.9 , pp. 833-840
    • Eaton, J.W.1    Qian, M.2
  • 54
    • 0029151231 scopus 로고
    • Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation
    • 10.1172/JCI118205 7657835
    • Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation. Kadiiska MB, Burkitt MJ, Xiang QH, Mason RP, J Clin Invest 1995 96 1653 7 10.1172/JCI118205 7657835
    • (1995) J Clin Invest , vol.96 , pp. 1653-1657
    • Kadiiska, M.B.1    Burkitt, M.J.2    Xiang, Q.H.3    Mason, R.P.4
  • 55
    • 0019335160 scopus 로고
    • Cardiolipin requirement by cytochrome oxidase and the catalytic role of phospholipid
    • 10.1016/0006-291X(80)90622-1 6249285
    • Cardiolipin requirement by cytochrome oxidase and the catalytic role of phospholipid. Fry M, Green DE, Biochem Biophys Res Commun 1980 93 1238 46 10.1016/0006-291X(80)90622-1 6249285
    • (1980) Biochem Biophys Res Commun , vol.93 , pp. 1238-1246
    • Fry, M.1    Green, D.E.2
  • 56
    • 0020057828 scopus 로고
    • Adriamycin inactivates cytochrome C oxidase by exclusion of the enzyme from its cardiolipin essential environment
    • DOI 10.1016/0006-291X(82)91976-3
    • Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment. Goormaghtigh E, Brasseur R, Ruysschaert JM, Biochem Biophys Res Commun 1982 104 314 20 10.1016/0006-291X(82) 91976-3 6280691 (Pubitemid 12146310)
    • (1982) Biochemical and Biophysical Research Communications , vol.104 , Issue.1 , pp. 314-320
    • Goormaghtigh, B.1    Brasseur, R.2    Ruysschaert, J.M.3
  • 57
    • 0025600464 scopus 로고
    • Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload
    • 10.1172/JCI114934 2123889
    • Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload. Houglum K, Filip M, Witztum JL, Chojkier M, J Clin Invest 1990 86 1991 8 10.1172/JCI114934 2123889
    • (1990) J Clin Invest , vol.86 , pp. 1991-1998
    • Houglum, K.1    Filip, M.2    Witztum, J.L.3    Chojkier, M.4
  • 58
    • 0025674536 scopus 로고
    • Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences
    • Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Stadtman ER, Free Radic Biol Med 1990 9 315 25 10.1016/0891-5849(90)90006-5 2283087 (Pubitemid 120036900)
    • (1990) Free Radical Biology and Medicine , vol.9 , Issue.4 , pp. 315-325
    • Stadtman, E.R.1
  • 59
    • 0030056515 scopus 로고    scopus 로고
    • Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
    • Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. Pitkanen S, Robinson BH, J Clin Invest 1996 98 345 51 10.1172/JCI118798 8755643 (Pubitemid 26255732)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.2 , pp. 345-351
    • Pitkanen, S.1    Robinson, B.H.2
  • 60
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • 10.1038/nature09663 21124315
    • A role for mitochondria in NLRP3 inflammasome activation. Zhou R, Yazdi AS, Menu P, Tschopp J, Nature 2011 469 221 5 10.1038/nature09663 21124315
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 61
    • 38849156952 scopus 로고    scopus 로고
    • Heart mitochondria: Gates of life and death
    • DOI 10.1093/cvr/cvm005
    • Heart mitochondria: gates of life and death. Gustafsson AB, Gottlieb RA, Cardiovasc Res 2008 77 334 43 18006487 (Pubitemid 351197632)
    • (2008) Cardiovascular Research , vol.77 , Issue.2 , pp. 334-343
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 62
    • 77956178165 scopus 로고    scopus 로고
    • Optical imaging of mitochondrial function uncovers actively propagating waves of mitochondrial membrane potential collapse across intact heart
    • 10.1016/j.yjmcc.2010.07.002 20624394
    • Optical imaging of mitochondrial function uncovers actively propagating waves of mitochondrial membrane potential collapse across intact heart. Lyon AR, Joudrey PJ, Jin D, Nass RD, Aon MA, O'Rourke B, Akar FG, J Mol Cell Cardiol 2010 49 565 75 10.1016/j.yjmcc.2010.07.002 20624394
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 565-575
    • Lyon, A.R.1    Joudrey, P.J.2    Jin, D.3    Nass, R.D.4    Aon, M.A.5    O'Rourke, B.6    Akar, F.G.7
  • 63
    • 79959945510 scopus 로고    scopus 로고
    • Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial
    • 10.3324/haematol.2010.032862 21393329
    • Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD, Haematologica 2011 96 1055 8 10.3324/haematol.2010.032862 21393329
    • (2011) Haematologica , vol.96 , pp. 1055-1058
    • Wood, J.C.1    Glynos, T.2    Thompson, A.3    Giardina, P.4    Harmatz, P.5    Kang, B.P.6    Paley, C.7    Coates, T.D.8
  • 64
    • 58149402407 scopus 로고    scopus 로고
    • Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation
    • 10.1182/blood-2008-06-161919 18796625
    • Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation. Kakhlon O, Manning H, Breuer W, Melamed-Book N, Lu C, Cortopassi G, Munnich A, Cabantchik ZI, Blood 2008 112 5219 27 10.1182/blood-2008-06-161919 18796625
    • (2008) Blood , vol.112 , pp. 5219-5227
    • Kakhlon, O.1    Manning, H.2    Breuer, W.3    Melamed-Book, N.4    Lu, C.5    Cortopassi, G.6    Munnich, A.7    Cabantchik, Z.I.8
  • 65
    • 36448937511 scopus 로고    scopus 로고
    • Deferiprone in the treatment of transfusion-dependent thalassemia: A review and perspective
    • Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective. Galanello R, Ther Clin Risk Manag 2007 3 795 805 18473004 (Pubitemid 350162079)
    • (2007) Therapeutics and Clinical Risk Management , vol.3 , Issue.5 , pp. 795-805
    • Galanello, R.1
  • 66
    • 77950945189 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state
    • 10.1124/dmd.109.030833 20097723
    • Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state. Waldmeier F, Bruin GJ, Glaenzel U, Hazell K, Sechaud R, Warrington S, Porter JB, Drug Metab Dispos 2010 38 808 16 10.1124/dmd.109.030833 20097723
    • (2010) Drug Metab Dispos , vol.38 , pp. 808-816
    • Waldmeier, F.1    Bruin, G.J.2    Glaenzel, U.3    Hazell, K.4    Sechaud, R.5    Warrington, S.6    Porter, J.B.7
  • 67
    • 0035138693 scopus 로고    scopus 로고
    • Deferoxamine pharmacokinetics
    • Deferoxamine pharmacokinetics. Porter JB, Semin Hematol 2001 38 Suppl 1 63 8 11206963 (Pubitemid 32110273)
    • (2001) Seminars in Hematology , vol.38 , Issue.1 SUPPL. 1 , pp. 63-68
    • Porter, J.B.1
  • 68
    • 0029097965 scopus 로고
    • Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo
    • 7655028
    • Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo. Shalev O, Repka T, Goldfarb A, Grinberg L, Abrahamov A, Olivieri NF, Rachmilewitz EA, Hebbel RP, Blood 1995 86 2008 13 7655028
    • (1995) Blood , vol.86 , pp. 2008-2013
    • Shalev, O.1    Repka, T.2    Goldfarb, A.3    Grinberg, L.4    Abrahamov, A.5    Olivieri, N.F.6    Rachmilewitz, E.A.7    Hebbel, R.P.8
  • 70
    • 70450215592 scopus 로고    scopus 로고
    • Deferiprone chelation therapy for thalassemia major
    • 10.1159/000243800 19907153
    • Deferiprone chelation therapy for thalassemia major. Galanello R, Campus S, Acta Haematol 2009 122 155 64 10.1159/000243800 19907153
    • (2009) Acta Haematol , vol.122 , pp. 155-164
    • Galanello, R.1    Campus, S.2
  • 73
    • 77953779950 scopus 로고    scopus 로고
    • The effect of deferasirox on cardiac iron in thalassemia major: Impact of total body iron stores
    • 10.1182/blood-2009-11-250308 20421452
    • The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Wood JC, Kang BP, Thompson A, Giardina P, Harmatz P, Glynos T, Paley C, Coates TD, Blood 2010 116 537 43 10.1182/blood-2009-11-250308 20421452
    • (2010) Blood , vol.116 , pp. 537-543
    • Wood, J.C.1    Kang, B.P.2    Thompson, A.3    Giardina, P.4    Harmatz, P.5    Glynos, T.6    Paley, C.7    Coates, T.D.8
  • 75
    • 0028931345 scopus 로고
    • Iron chelators induce apoptosis in proliferating cells
    • 7833261
    • Iron chelators induce apoptosis in proliferating cells. Hileti D, Panayiotidis P, Hoffbrand AV, Br J Haematol 1995 89 181 7 7833261
    • (1995) Br J Haematol , vol.89 , pp. 181-187
    • Hileti, D.1    Panayiotidis, P.2    Hoffbrand, A.V.3
  • 79
    • 77950915849 scopus 로고    scopus 로고
    • Ion redistribution as a therapeutic strategy for treating diseases of localized iron accumulation
    • 10.1139/Y09-128
    • Ion redistribution as a therapeutic strategy for treating diseases of localized iron accumulation. Kakhlon O, Breuer W, Munnich A, Cabantchik ZI, Can Physiol Pharmacol 2010 88 187 96 10.1139/Y09-128
    • (2010) Can Physiol Pharmacol , vol.88 , pp. 187-196
    • Kakhlon, O.1    Breuer, W.2    Munnich, A.3    Cabantchik, Z.I.4
  • 80
    • 80052243548 scopus 로고    scopus 로고
    • Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal
    • 21091647
    • Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal. Sohn YS, Mitterstiller AM, Breuer W, Weiss G, Cabantchik ZI, Br J Pharmacol 2011 164 406 18 21091647
    • (2011) Br J Pharmacol , vol.164 , pp. 406-418
    • Sohn, Y.S.1    Mitterstiller, A.M.2    Breuer, W.3    Weiss, G.4    Cabantchik, Z.I.5
  • 81
    • 77952488261 scopus 로고    scopus 로고
    • Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG
    • 10.1007/s10534-009-9281-9 19997770
    • Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG. Gaboriau F, Leray AM, Ropert M, Gouffier L, Cannie I, Troadec MB, Loréal O, Brissot P, Lescoat G, Biometals 2010 23 231 45 10.1007/s10534-009-9281-9 19997770
    • (2010) Biometals , vol.23 , pp. 231-245
    • Gaboriau, F.1    Leray, A.M.2    Ropert, M.3    Gouffier, L.4    Cannie, I.5    Troadec, M.B.6    Loréal, O.7    Brissot, P.8    Lescoat, G.9
  • 82
    • 80955178788 scopus 로고    scopus 로고
    • Successful chelation therapy with the combination of deferasirox and deferiprone in a patient with thalassaemia major and persisting severe iron overload after single-agent chelation therapies
    • 10.1111/j.1365-2141.2011.08626.x 21615376
    • Successful chelation therapy with the combination of deferasirox and deferiprone in a patient with thalassaemia major and persisting severe iron overload after single-agent chelation therapies. Voskaridou E, Christoulas D, Terpos E, Br J Haematol 2011 154 654 6 10.1111/j.1365-2141.2011.08626.x 21615376
    • (2011) Br J Haematol , vol.154 , pp. 654-656
    • Voskaridou, E.1    Christoulas, D.2    Terpos, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.