Deferasirox decreases age-associated iron accumulation in the aging F344XBN rat heart and liver

Cardiovascular Toxicology

Volumn 10, Issue 2, 2010, Pages 108-116

  Arvapalli, Ravi Kumar ^a   Paturi, Satyanarayana ^a   Laurino, Joseph P ^b   Katta, Anjaiah ^c   Kakarla, Sunil K ^c   Gadde, Murali K ^a   Wu, Miaozong ^a   Rice, Kevin M ^a   Walker, Ernest M ^a,c   Wehner, Paulette ^c   Blough, Eric R ^a,c  

^a MARSHALL UNIVERSITY   (United States)

^b UNIVERSITY OF TAMPA   (United States)

^c MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Bax to Bcl2 ratio; Caspase 3; Deferasirox; Heart; Iron

Indexed keywords

CASPASE 3; DEFERASIROX; FERRITIN; IRON REGULATORY FACTOR; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; BENZOIC ACID DERIVATIVE; IRON; IRON CHELATING AGENT; TRACE ELEMENT; TRIAZOLE DERIVATIVE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; HEART INJURY; HEART MUSCLE CELL; IRON CHELATION; KIDNEY FUNCTION; KIDNEY INJURY; LIVER FUNCTION; LIVER INJURY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; TISSUE LEVEL; ANIMAL; BODY WEIGHT; CHEMISTRY; DRUG EFFECTS; FISCHER 344 RAT; HEART; HEART MUSCLE; IRON OVERLOAD; LIVER; METABOLISM; ORGAN SIZE; PATHOLOGY;

AGING; ANIMALS; APOPTOSIS; BENZOIC ACIDS; BODY WEIGHT; HEART; IN SITU NICK-END LABELING; IRON; IRON CHELATING AGENTS; IRON OVERLOAD; LIVER; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SIZE; RATS; RATS, INBRED F344; TRACE ELEMENTS; TRIAZOLES; BENZOATES;

ANIMALIA; RATTUS;

EID: 77956393185     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12012-010-9068-9     Document Type: Article

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