Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation

Chemistry and Biology

Volumn 18, Issue 12, 2011, Pages 1527-1536

  Lechner, Anna ^a   Eustáquio, Alessandra S ^a,d   Gulder, Tobias A M ^a,e   Hafner, Mathias ^c   Moore, Bradley S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^e UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; ENZYME INHIBITOR; LACTONE; PROTEASOME; PYRROLE DERIVATIVE; RECOMBINANT PROTEIN; SALINOSPORAMIDE A;

AMINO ACID SEQUENCE; ARTICLE; DRUG ANTAGONISM; GENETICS; METABOLISM; MICROMONOSPORACEAE; MOLECULAR GENETICS; PROTEIN BINDING;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; ENZYME INHIBITORS; LACTONES; MICROMONOSPORACEAE; MOLECULAR SEQUENCE DATA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PYRROLES; RECOMBINANT PROTEINS;

EID: 84555190558     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.10.014     Document Type: Article

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