Discovery and development of the anticancer agent salinosporamide A (NPI-0052)

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 6, 2009, Pages 2175-2180

  Fenical, William ^a   Jensen, Paul R ^a   Palladino, Michael A ^b   Lam, Kin S ^b   Lloyd, G Kenneth ^b   Potts, Barbara C ^b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Nereus Pharmaceuticals Inc   (United States)

Author keywords

Marine actinomycetes; NPI 0052; Proteasome inhibitor; Salinosporamide A

Indexed keywords

BORTEZOMIB; LACTACYSTIN BETA LACTONE; SALINOSPORAMIDE A;

ACTINOBACTERIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; CLINICAL TRIAL; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; LOW DRUG DOSE; LYMPHOMA; MULTIPLE MYELOMA; NONHUMAN; PROTEINASE INHIBITION; SOLID TUMOR; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; DRUG DISCOVERY; DRUGS, INVESTIGATIONAL; LACTONES; MOLECULAR STRUCTURE; PYRROLES;

ACTINOBACTERIA (CLASS);

EID: 62149103377     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.10.075     Document Type: Article

References (44)

1. Bérdy J. J. Antibiot. 58 (2005) 1
2. Weyland H. Nature 223 (1969) 858
3. Okami Y., and Okazaki T. J. Antibiot. 27 (1974) 240
4. Goodfellow M., and Haynes J.A. Actinomycetes in Marine Sediments. In: Ortiz-Ortiz L., Bojalil L.F., and Yakoleff V. (Eds). Biological Biochemical and Biomedical Aspects of Actinomycetes (1984), Academic Press Inc., Orlando 453-472
5. Jensen P.R., Dwight R., and Fenical W. Appl. Environ. Microbiol. 57 (1991) 1102
6. Mincer T.J., Jensen P.R., Kauffman C.A., and Fenical W. Appl. Environ. Microbiol. 68 (2002) 5005
7. Maldonado L., Fenical W., Goodfellow M., Jensen P.R., Kauffman C.K., and Ward A.C. Internat. J. System. Evol. Microbiol. 55 (2005) 1759
8. Feling R.H., Buchanan G.O., Mincer T.J., Kauffman C.A., Jensen P.R., and Fenical W. Angew. Chem. Int. Ed. 42 (2003) 355
9. Omura S., Matsuzaki K., Fujimoto T., Kosuge K., Furuya T., Fujita S., and Nakagawa A. J. Antibiot. (Tokyo) 441 (1991) 113
10. Tomoda H., and Omura S. J. Pharm. Soc. Japan (Yakugaku Zasshi) 12010 (2000) 935
11. Fenteany G., Standaert R.F., Lane W.S., Choi S., Corey E.J., and Schreiber S.L. Science 268 (1995) 726
12. Hershko A., and Ciechanover A. Ann. Rev. Biochem. 67 (1998) 425
13. Adams J. Proteasome Inhibitors in Cancer Therapy (2004), Humana Press, Totowa, NJ
14. Bross P.F., Kane R., Farrell A.T., Abraham S., Benson K., Brower M.E., Bradley S., Gobburu J.V., Goheer A., Lee S.-L., Leighton J., Liang C.Y., Lostritto R.T., McGuinn W.D., Morse D.E., Rahman A., Rosario L.A., Verbois S.L., Williams G., Wang Y.-C., and Pazdur R. Clin. Cancer Res. 10 (2004) 3954
15. Richarson P.G., Barlogie B., Berenson J., Singhal S., Jagannath S., Irwin D., Rajkumar S.V., Srkalovic G., Alsina M., Alexanian R., Seigel D., Orlowski R.Z., Kuter D., Limentani S.A., Lee S., Hideshima T., Esseltine D.L., Kauffman M., Adams J., Schenkein D.P., and Anderson K.C. N. Engl. J. Med. 348 (2003) 2609
16. Groll M., Ditzel L., Löwe J., Stock D., Bochtler M., Bartunik H.D., and Huber R. Nature 386 (1997) 463
17. Löwe J., Stock D., Jap B., Zwickl P., Baumeister W., and Huber R. Science 268 (1995) 533
18. Kisselev A.F., and Goldberg A.L. Chem. Biol. 8 (2001) 739
19. Wilk S., Pereira M., and Yu B. Biomed. Biochim. Acta 50 (1991) 471
20. Chauhan D., Catley L., Li G., Podar K., Hideshima T., Velankar M., Mitsiades C., Mitsiades N., Yasui H., Letai A., Ovaa H., Berkers C., Nicholson B., Chao T.-H., Neuteboom S.T.C., Richardson P., Palladino M., and Anderson K.C. Cancer Cell 8 (2005) 407
21. Kisselev A.F., Callard A., and Goldberg A.L. J. Biol. Chem. 281 (2006) 8582
22. Ahn K.S., Sethi G., Chao T.H., Neuteboom S., Chaturvedi M., Palladino M., Younes A., and Aggarwal B. Blood 110 (2007) 2286
23. Groll M., Huber R., and Potts B.C.M. J. Am. Chem. Soc. 128 (2006) 5136
24. Sedriks J.A. Corrosions of Stainless Steels. 2nd ed. (1996), Wiley, New York
25. Denora N., Potts B.C.M., and Stella V.J. J. Pharm. Sci. 96 (2007) 2037
26. Tsueng G., and Lam K.S. J. Antibiot. 60 (2007) 469
27. Reddy L.R., Saravanan P., and Corey E.J. J. Am. Chem. Soc. 126 (2004) 6230
28. Endo A., and Danishefsky S.J. J. Am. Chem. Soc. 127 (2005) 8298
29. Mulholland N.P., Pattenden G., and Walters I.A.S. Org. Biomol. Chem. 4 (2006) 2845
30. Ling T., Macherla V.R., Manam R.R., McArthur K.A., and Potts B.C.M. Org. Lett. 9 (2007) 2289
31. Caubert V., Masse J., Retailleau P., and Langlois N. Tetrahedron Lett. 48 (2007) 381
32. Ma G., Nguyen H., and Romo D. Org. Lett. 9 (2007) 2143
33. Macherla V.R., Mitchell S..S., Manam R.R., Reed K., Chao T.-H., Nicholson B., Deyanat-Yazdi G., Mai B., Jensen P.R., Fenical W., Neuteboom S.T.C., Lam K.S., Palladino M.A., and Potts B.C.M. J. Med. Chem. 48 (2005) 3684
34. Williams P.G., Buchanan G.O., Feling R.H., Kauffman C.A., Jensen P.R., and Fenical W. J. Org. Chem. 70 (2005) 6196
35. Reed K.A., Manam R.R., Mitchell S.S., Xu J., Teisan S., Chao T.-H., Deyanat-Yazdi G., Neuteboom S.T.C., Lam K.S., and Potts B.C.M. J. Nat. Prod. 70 (2007) 269
36. Chauhan D., Singh A., Brahmandam M., Podar K., Hideshima T., Richardson P., Munshi N., Palladino M., and Anderson K. Blood 111 (2008) 1654
37. Cusack J., Liu R., Xia L., Pien C., Niu W., Palombella V., Chao T.-H., Neuteboom S.T., and Palladino M. Clin. Cancer Res. 12 (2006) 6758
38. Sloss C.M., Wang F., Liu R., Houston M., Ljungman D., Palladino M.A., and Cusack J.C. Clin. Cancer Res. 14 (2008) 5116
39. Baritaki S., Suzuki E., Umezawa K., Spandidos D., Berenson J., Daniels T.R., Penichet M.L., Palladino M., and Bonavida B. J. Immunol. 180 (2008) 6199
40. Roccaro A., Jia X., Sacco A., Melhem M., Moreau A., Leleu X., Ngo H., Runels J., Azab A., Azab F., Burwick N., Farag M., Treon S., Palladino M., Hideshima T., Chauhan D., Anderson K., and Ghobrial I. Blood 111 (2008) 4752
41. Miller C., Ban K., Dujka M., McConkey D., Palladino M., and Chandra J. Blood 110 (2007) 267
42. Ruiz S., Krupnik Y., Keating M., Chandra J., Palladino M., and McConkey D. Mol. Cancer Ther. 5 (2006) 1836
43. Kin Y., and Kaelin W.G. Semin. Oncol. 33 (2006) 588
44. Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W., Jensen P.R., and Moore B.S. Proc. Natl. Acad. Sci. USA 104 (2007) 10376