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Volumn 13, Issue 3, 2010, Pages 263-273

Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BUTYROLACTONE; RECEPTOR; REGULATOR PROTEIN; STREPTOMYCES ANTIBIOTIC REGULATORY PROTEIN; UNCLASSIFIED DRUG;

EID: 77952909070     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2010.02.008     Document Type: Review
Times cited : (170)

References (52)
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    • Lee P.C., Umeyama T., and Horinouchi S. afsS is a target of AfsR, a transcriptional factor with ATPase activity that globally controls secondary metabolism in Streptomyces coelicolor A3(2). Mol Microbiol 43 (2002) 1413-1430
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    • Nitrogen metabolism in Streptomyces coelicolor: transcriptional and post-translational regulation
    • A good article on the different levels of regulation of nitrogen metabolism.
    • Reuther J., and Wohlleben W. Nitrogen metabolism in Streptomyces coelicolor: transcriptional and post-translational regulation. J Mol Microbiol Biotechnol 12 (2007) 139-146. A good article on the different levels of regulation of nitrogen metabolism.
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    • Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a DeltaphoP mutant
    • Outstanding article on the transcriptomics and proteomics of phosphate control in Streptomyces.
    • Rodríguez-García A., Barreiro C., Santos-Beneit F., Sola-Landa A., and Martín J.F. Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a DeltaphoP mutant. Proteomics 7 (2007) 2410-2429. Outstanding article on the transcriptomics and proteomics of phosphate control in Streptomyces.
    • (2007) Proteomics , vol.7 , pp. 2410-2429
    • Rodríguez-García, A.1    Barreiro, C.2    Santos-Beneit, F.3    Sola-Landa, A.4    Martín, J.F.5
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    • The high-affinity phosphate-binding protein PstS is accumulated under high fructose concentrations and mutation of the corresponding gene affects differentiation in Streptomyces lividans
    • Díaz M., Esteban A., Fernández-Abalos J.M., and Santamaría R.I. The high-affinity phosphate-binding protein PstS is accumulated under high fructose concentrations and mutation of the corresponding gene affects differentiation in Streptomyces lividans. Microbiology 151 (2005) 2583-2592
    • (2005) Microbiology , vol.151 , pp. 2583-2592
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    • Expression of the pstS gene of Streptomyces lividans is regulated by the carbon source and is partially independent of the PhoP regulator
    • An article describing interesting observations on the interaction of phosphate and carbon sources.
    • Esteban A., Díaz M., Yepes A., and Santamaría R.I. Expression of the pstS gene of Streptomyces lividans is regulated by the carbon source and is partially independent of the PhoP regulator. BMC Microbiol 8 (2008) 201-212. An article describing interesting observations on the interaction of phosphate and carbon sources.
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    • Esteban, A.1    Díaz, M.2    Yepes, A.3    Santamaría, R.I.4
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    • The Streptomyces coelicolor glnR gene encodes a protein similar to other bacterial response regulators
    • Wray Jr. L.V., and Fisher S.H. The Streptomyces coelicolor glnR gene encodes a protein similar to other bacterial response regulators. Gene 130 (1993) 145-150
    • (1993) Gene , vol.130 , pp. 145-150
    • Wray Jr., L.V.1    Fisher, S.H.2
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    • Iron-regulatory proteins DmdR1 and DmdR2 of Streptomyces coelicolor form two different DNA-protein complexes with iron boxes
    • Flores F.J., and Martín J.F. Iron-regulatory proteins DmdR1 and DmdR2 of Streptomyces coelicolor form two different DNA-protein complexes with iron boxes. Biochem J 380 (2004) 497-503
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    • Flores, F.J.1    Martín, J.F.2
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    • The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis
    • A good study of the metabolic engineering of phosphate control of pimaricin biosynthesis.
    • Mendes M.V., Tunca S., Antón N., Recio E., Sola-Landa A., Aparicio J.F., and Martín J.F. The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis. Metabol Eng 9 (2007) 217-227. A good study of the metabolic engineering of phosphate control of pimaricin biosynthesis.
    • (2007) Metabol Eng , vol.9 , pp. 217-227
    • Mendes, M.V.1    Tunca, S.2    Antón, N.3    Recio, E.4    Sola-Landa, A.5    Aparicio, J.F.6    Martín, J.F.7
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    • A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds
    • This was the first report on the characterization of ccaR and the metabolic engineering of cephamycin C and clavulanic acid production by amplification of ccaR.
    • Pérez-Llarena F.J., Liras P., Rodríguez-García A., and Martín J.F. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds. J Bacteriol 179 (1997) 2053-2059. This was the first report on the characterization of ccaR and the metabolic engineering of cephamycin C and clavulanic acid production by amplification of ccaR.
    • (1997) J Bacteriol , vol.179 , pp. 2053-2059
    • Pérez-Llarena, F.J.1    Liras, P.2    Rodríguez-García, A.3    Martín, J.F.4
  • 50
    • 35348922983 scopus 로고    scopus 로고
    • Enhancement of clavulanic acid by replicative and integrative expression of ccaR and cas2 in Streptomyces clavuligerus NRRL3585
    • Viet H.T., Malla S., Park B.C., Liou K., Lee H.C., and Sohng J.K. Enhancement of clavulanic acid by replicative and integrative expression of ccaR and cas2 in Streptomyces clavuligerus NRRL3585. J Microbiol Biotechnol 17 (2007) 1538-1545
    • (2007) J Microbiol Biotechnol , vol.17 , pp. 1538-1545
    • Viet, H.T.1    Malla, S.2    Park, B.C.3    Liou, K.4    Lee, H.C.5    Sohng, J.K.6
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    • Improvement in doxorubicin productivity by overexpression of regulatory genes in Streptomyces peucetius
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    • Malla S., Niraula N.P., Liou K., and Kyung J. Improvement in doxorubicin productivity by overexpression of regulatory genes in Streptomyces peucetius. Res Microbiol (2010) 10.1016/j.resmic.2009.12.003
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    • Malla, S.1    Niraula, N.P.2    Liou, K.3    Kyung, J.4
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    • 77249153701 scopus 로고    scopus 로고
    • Genome-minimized Streptomyces host of the heterologous expression of secondary metabolism
    • A very recent article on the possibility of minimizing Streptomyces genomes.
    • Komatsu M., Uchiyama T., Omura S., Cane D.E., and Ikeda H. Genome-minimized Streptomyces host of the heterologous expression of secondary metabolism. Proc Natl Acad Sci USA 107 (2010) 2646-2651. A very recent article on the possibility of minimizing Streptomyces genomes.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2646-2651
    • Komatsu, M.1    Uchiyama, T.2    Omura, S.3    Cane, D.E.4    Ikeda, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.