-
2
-
-
0037420819
-
-
6-aryl-pyrazolo[3,4-b]pyridines
-
J. Witherington V. Bordas S. L. Garland D. M. B. Hickey R. J. Ife J. Liddle M. Saunders D. G. Smith R. W. Ward Bioorg. Med. Chem. Lett. 2003 13 1577 1580
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 1577-1580
-
-
Witherington, J.1
Bordas, V.2
Garland, S.L.3
Hickey, D.M.B.4
Ife, R.J.5
Liddle, J.6
Saunders, M.7
Smith, D.G.8
Ward, R.W.9
-
3
-
-
12444280004
-
-
6-Heteroaryl-pyrazolo[3,4-b]pyridines
-
J. Witherington V. Bordas A. Gaiba N. S. Garton A. Naylor A. D. Rawlings B. P. Slingsby D. G. Smith A. K. Takle R. W. Ward Bioorg. Med. Chem. Lett. 2003 13 3055 3057
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 3055-3057
-
-
Witherington, J.1
Bordas, V.2
Gaiba, A.3
Garton, N.S.4
Naylor, A.5
Rawlings, A.D.6
Slingsby, B.P.7
Smith, D.G.8
Takle, A.K.9
Ward, R.W.10
-
4
-
-
0043022153
-
-
J. Witherington V. Bordas A. Gaiba N. S. Garton A. Naylor A. D. Rawlings B. P. Slingsby D. G. Smith A. K. Takle R. W. Ward Bioorg. Med. Chem. Lett. 2003 13 3059 3062
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 3059-3062
-
-
Witherington, J.1
Bordas, V.2
Gaiba, A.3
Garton, N.S.4
Naylor, A.5
Rawlings, A.D.6
Slingsby, B.P.7
Smith, D.G.8
Takle, A.K.9
Ward, R.W.10
-
6
-
-
0039052019
-
-
EP 339358, [Chem. Abstr., 1990,]
-
Y. Fujikama, M. Suzuki, H. Iwasaki, M. Sakashita, M. Kitahara, EP 339358, 1989 [Chem. Abstr., 1990, 113, 23903]
-
(1989)
, vol.113
, pp. 23903
-
-
Fujikama, Y.1
Suzuki, M.2
Iwasaki, H.3
Sakashita, M.4
Kitahara, M.5
-
7
-
-
28544436111
-
-
F. Manetti S. Schenone F. Bondavalli C. Brullo O. Bruno A. Ranise L. Mosti G. Menozzi P. Fossa M. L. Trincavelli C. Martini A. Martinelli C. Tintori M. Botta J. Med. Chem. 2005 48 7172 7185
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7172-7185
-
-
Manetti, F.1
Schenone, S.2
Bondavalli, F.3
Brullo, C.4
Bruno, O.5
Ranise, A.6
Mosti, L.7
Menozzi, G.8
Fossa, P.9
Trincavelli, M.L.10
Martini, C.11
Martinelli, A.12
Tintori, C.13
Botta, M.14
-
8
-
-
47149103616
-
-
J. N. Hamblin T. D. R. Angell S. P. Ballantine C. M. Cook A. W. J. Cooper J. Dawson C. J. Delves P. S. Jones M. Lindvall F. S. Lucas C. J. Mitchell M. Y. Neu L. E. Ranshaw Y. E. Solanke D. O. Somers J. O. Wiseman Bioorg. Med. Chem. Lett. 2008 18 4237 4241
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 4237-4241
-
-
Hamblin, J.N.1
Angell, T.D.R.2
Ballantine, S.P.3
Cook, C.M.4
Cooper, A.W.J.5
Dawson, J.6
Delves, C.J.7
Jones, P.S.8
Lindvall, M.9
Lucas, F.S.10
Mitchell, C.J.11
Neu, M.Y.12
Ranshaw, L.E.13
Solanke, Y.E.14
Somers, D.O.15
Wiseman, J.O.16
-
9
-
-
27944439591
-
-
L. Revesz E. Blum F. E. Di Padova T. Buhl R. Feifel H. Gram P. Hiestand U. Manning U. Neumann G. Rucklin Bioorg. Med. Chem. Lett. 2006 16 262 266
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 262-266
-
-
Revesz, L.1
Blum, E.2
Di Padova, F.E.3
Buhl, T.4
Feifel, R.5
Gram, H.6
Hiestand, P.7
Manning, U.8
Neumann, U.9
Rucklin, G.10
-
10
-
-
84555193457
-
-
WO9534563 A1
-
Y. L. Chen, WO9534563 A1, 1995
-
(1995)
-
-
Chen, Y.L.1
-
11
-
-
84555172577
-
-
US4891375
-
J. A. Lowe, US4891375, 1990
-
(1990)
-
-
Lowe, J.A.1
-
15
-
-
0027096411
-
-
G. D. Hartman M. S. Egberston W. Halczenko W. L. Laswell M. E. Duggan R. L. Smith A. M. Naylor P. D. Manno R. J. Lynch G. Zhang C. T. Chang R. J. Gould J. Med. Chem. 1992 35 4640 4642
-
(1992)
J. Med. Chem.
, vol.35
, pp. 4640-4642
-
-
Hartman, G.D.1
Egberston, M.S.2
Halczenko, W.3
Laswell, W.L.4
Duggan, M.E.5
Smith, R.L.6
Naylor, A.M.7
Manno, P.D.8
Lynch, R.J.9
Zhang, G.10
Chang, C.T.11
Gould, R.J.12
-
17
-
-
25844464785
-
-
I. Rivero-Cruz L. Acevedo J. A. Guerrero S. Martinez R. Bye R. Pereda-Miranda S. Franzblau B. N. Timmermann R. Mata J. Pharm. Pharmacol. 2005 5 1117 1126
-
(2005)
J. Pharm. Pharmacol.
, vol.5
, pp. 1117-1126
-
-
Rivero-Cruz, I.1
Acevedo, L.2
Guerrero, J.A.3
Martinez, S.4
Bye, R.5
Pereda-Miranda, R.6
Franzblau, S.7
Timmermann, B.N.8
Mata, R.9
-
19
-
-
20344405982
-
-
J. A. Aikins M. Haurez J. R. Rizzo J. P. Van Hoeck W. Brione J. P. Kestemont C. Stevens X. Lemair G. A. Stephenson E. Marlot M. Forst I. N. Houpis J. Org. Chem. 2005 70 4695 4705
-
(2005)
J. Org. Chem.
, vol.70
, pp. 4695-4705
-
-
Aikins, J.A.1
Haurez, M.2
Rizzo, J.R.3
Van Hoeck, J.P.4
Brione, W.5
Kestemont, J.P.6
Stevens, C.7
Lemair, X.8
Stephenson, G.A.9
Marlot, E.10
Forst, M.11
Houpis, I.N.12
-
20
-
-
0034727872
-
-
D. P. Rotella Z. Sun Y. Zhu J. Krupinski R. Pongrac L. Seliger D. Normandin J. E. Macor J. Med. Chem. 2000 43 5037 5043
-
(2000)
J. Med. Chem.
, vol.43
, pp. 5037-5043
-
-
Rotella, D.P.1
Sun, Z.2
Zhu, Y.3
Krupinski, J.4
Pongrac, R.5
Seliger, L.6
Normandin, D.7
MacOr, J.E.8
-
27
-
-
84555198435
-
-
WO2011045344 A1
-
K. Bedjeguelal, R. Rabot, EI B. Kaloun, P. Mayer, A. Marchand, N. Rahier, P. Schambel, H. Bienayme, WO2011045344 A1, 2011
-
(2011)
-
-
Bedjeguelal, K.1
Rabot, R.2
Kaloun, E.I.B.3
Mayer, P.4
Marchand, A.5
Rahier, N.6
Schambel, P.7
Bienayme, H.8
-
28
-
-
84555193456
-
-
US20100113415 A1
-
H. A. Rajapakse, K. P. Moore, P. G. Nantermet, J. M. Sanders, S. Parmentier-Batteur, R. J. Mark, US20100113415 A1, 2010
-
(2010)
-
-
Rajapakse, H.A.1
Moore, K.P.2
Nantermet, P.G.3
Sanders, J.M.4
Parmentier-Batteur, S.5
Mark, R.J.6
-
29
-
-
84555198433
-
-
WO2010059788 A1
-
J. Dotson, T. Heffron, A. G. Olivero, D. P. Sutherlin, S. Staben, S. Wang, B.-Y. Zhu, I. S. Chuckowree, A. J. Folkes, N. C. Wan, WO2010059788 A1, 2010
-
(2010)
-
-
Dotson, J.1
Heffron, T.2
Olivero, A.G.3
Sutherlin, D.P.4
Staben, S.5
Wang, S.6
Zhu, B.-Y.7
Chuckowree, I.S.8
Folkes, A.J.9
Wan, N.C.10
-
30
-
-
84555173675
-
-
WO2010078427 A1
-
M. Tandon, S. M. Ali, M. Ashwell, J. Wang, N. Namdev, J. Hill, D. Neil, C. Brassard, A. Filikov, R. Palma, D. Vensel, WO2010078427 A1, 2010
-
(2010)
-
-
Tandon, M.1
Ali, S.M.2
Ashwell, M.3
Wang, J.4
Namdev, N.5
Hill, J.6
Neil, D.7
Brassard, C.8
Filikov, A.9
Palma, R.10
Vensel, D.11
-
39
-
-
0035817055
-
-
J. Quiroga D. Mejia B. Insuasty R. Abonia M. Nogueras A. Sanchez J. Cobo J. N. Low Tetrahedron 2001 57 6947 6953
-
(2001)
Tetrahedron
, vol.57
, pp. 6947-6953
-
-
Quiroga, J.1
Mejia, D.2
Insuasty, B.3
Abonia, R.4
Nogueras, M.5
Sanchez, A.6
Cobo, J.7
Low, J.N.8
-
41
-
-
12144287141
-
-
I. Drizin R. J. Altenbach S. A. Buckner K. L. Whiteaker V. E. Scott J. F. Darbyshire V. Jayanti R. F. Henry M. J. Coghlan M. Gopalakrishnan W. A. Carroll Bioorg. Med. Chem. 2004 12 1895 1904
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 1895-1904
-
-
Drizin, I.1
Altenbach, R.J.2
Buckner, S.A.3
Whiteaker, K.L.4
Scott, V.E.5
Darbyshire, J.F.6
Jayanti, V.7
Henry, R.F.8
Coghlan, M.J.9
Gopalakrishnan, M.10
Carroll, W.A.11
|