The ATP-sensitive K + channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity

Diabetes

Volumn 61, Issue 1, 2012, Pages 241-249

  Fatehi, Mohammad ^a   Raja, Mobeen ^a   Carter, Christian ^a   Soliman, Daniel ^a   Holt, Andrew ^a   Light, Peter E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL ABCC8; BERYLLIUM FLUORIDE; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN; MAGNESIUM ION; NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; COMPUTER MODEL; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; HAPLOTYPE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK ASSESSMENT;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ALANINE; AMINO ACID SUBSTITUTION; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; ENZYME ACTIVATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KATP CHANNELS; MODELS, MOLECULAR; POLYMORPHISM, SINGLE NUCLEOTIDE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DRUG; RISK FACTORS; SERINE; TRANSFECTION;

EID: 84555177674     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0371     Document Type: Article

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