Acetaminophen-induced hepatotoxicity in a liver tissue model consisting of primary hepatocytes assembling around an endothelial cell network

Drug Metabolism and Disposition

Volumn 40, Issue 1, 2012, Pages 169-177

  Toyoda, Yu ^a   Tamai, Miho ^a   Kashikura, Kasumi ^b   Kobayashi, Shunsuke ^a   Fujiyama, Yoichi ^c   Soga, Tomoyoshi ^b   Tagawa, Yoh Ichi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c SHIMADZU CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; LACTATE DEHYDROGENASE; PARACETAMOL;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYP2E1 GENE; CYTOTOXICITY TEST; ENDOTHELIUM CELL; ENZYME RELEASE; GENE; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PECAM 1 GENE; PRIORITY JOURNAL; VWF GENE;

ACETAMINOPHEN; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DRUG-INDUCED LIVER INJURY; ENDOTHELIAL CELLS; HEPATOCYTES; HUMANS; LIVER; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC;

EID: 84455194051     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.041137     Document Type: Article

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