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Volumn 10, Issue 21, 2004, Pages 7402-7412

Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM 51; GAMMA INTERFERON; MESSENGER RNA; PERFORIN; TUMOR ANTIGEN; WT1 PROTEIN;

EID: 8444224189     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-0825     Document Type: Article
Times cited : (58)

References (53)
  • 2
    • 0036512435 scopus 로고    scopus 로고
    • Multiple myeloma: Evolving genetic events and host interactions
    • Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer 2002;2:175-87.
    • (2002) Nat Rev Cancer , vol.2 , pp. 175-187
    • Kuehl, W.M.1    Bergsagel, P.L.2
  • 3
    • 0037716629 scopus 로고    scopus 로고
    • Management of multiple myeloma: A systematic review and critical appraisal of published studies
    • Kumar A, Loughran T, Alsina M, Durie BG, Djulbegovic B. Management of multiple myeloma: a systematic review and critical appraisal of published studies. Lancet Oncol 2003;4:293-304.
    • (2003) Lancet Oncol , vol.4 , pp. 293-304
    • Kumar, A.1    Loughran, T.2    Alsina, M.3    Durie, B.G.4    Djulbegovic, B.5
  • 5
    • 0025099787 scopus 로고
    • Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
    • Call KM, Glaser T, Ito CY, et al. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 1990;60:509-20.
    • (1990) Cell , vol.60 , pp. 509-520
    • Call, K.M.1    Glaser, T.2    Ito, C.Y.3
  • 6
    • 0027209712 scopus 로고
    • The WT1 Wilms tumor gene product: A developmentally regulated transcription factor in the kidney that functions as a tumor suppressor
    • Rauscher FJ III. The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J 1993;7:896-903.
    • (1993) FASEB J , vol.7 , pp. 896-903
    • Rauscher III, F.J.1
  • 7
    • 0027328694 scopus 로고
    • The Wilms tumor gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma
    • Park S, Schalling M, Bernard A, et al. The Wilms tumor gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma. Nat Genet. 1993;4:415-20.
    • (1993) Nat Genet , vol.4 , pp. 415-420
    • Park, S.1    Schalling, M.2    Bernard, A.3
  • 8
    • 0025291908 scopus 로고
    • The candidate Wilms' tumor gene is involved in genitourinary development
    • Pritchard-Jones K, Fleming S, Davidson D, et al. The candidate Wilms' tumor gene is involved in genitourinary development. Nature (Lond) 1990;346:194-7.
    • (1990) Nature (Lond) , vol.346 , pp. 194-197
    • Pritchard-Jones, K.1    Fleming, S.2    Davidson, D.3
  • 9
    • 0035835816 scopus 로고    scopus 로고
    • Wilms tumor and the WT1 gene
    • Lee SB, Haber DA. Wilms tumor and the WT1 gene. Exp Cell Res 2001;264:74-99.
    • (2001) Exp Cell Res , vol.264 , pp. 74-99
    • Lee, S.B.1    Haber, D.A.2
  • 10
    • 0031010990 scopus 로고    scopus 로고
    • Expression of the Wilms' tumor gene (WT1) in normal hemopoiesis
    • Baird PN, Simmons PJ. Expression of the Wilms' tumor gene (WT1) in normal hemopoiesis. Exp Hematol 1997;25:312-20.
    • (1997) Exp Hematol , vol.25 , pp. 312-320
    • Baird, P.N.1    Simmons, P.J.2
  • 11
    • 0026751042 scopus 로고
    • Expression of the Wilms' tumor gene (WT1) in human leukemias
    • Miwa H, Beran M, Saunders GF. Expression of the Wilms' tumor gene (WT1) in human leukemias. Leukemia (Baltimore) 1992;6:405-9.
    • (1992) Leukemia (Baltimore) , vol.6 , pp. 405-409
    • Miwa, H.1    Beran, M.2    Saunders, G.F.3
  • 12
    • 0028130136 scopus 로고
    • WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
    • Inoue K, Sugiyama H, Ogawa H, et al. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood 1994;84:3071-9.
    • (1994) Blood , vol.84 , pp. 3071-3079
    • Inoue, K.1    Sugiyama, H.2    Ogawa, H.3
  • 13
    • 0028606895 scopus 로고
    • The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells
    • Brieger J, Weidmann E, Fenchel K, et al. The expression of the Wilms' tumor gene in acute myelocytic leukemias as a possible marker for leukemic blast cells. Leukemia (Baltimore) 1994;8:2138-43.
    • (1994) Leukemia (Baltimore) , vol.8 , pp. 2138-2143
    • Brieger, J.1    Weidmann, E.2    Fenchel, K.3
  • 14
    • 0029069227 scopus 로고
    • Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias
    • Menssen HD, Renkl H, Rodeck U, et al. Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia (Baltimore) 1995;9:1060-7.
    • (1995) Leukemia (Baltimore) , vol.9 , pp. 1060-1067
    • Menssen, H.D.1    Renkl, H.2    Rodeck, U.3
  • 15
    • 0037370833 scopus 로고    scopus 로고
    • The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia
    • Ogawa H, Tamaki H, Ikegame K, et al. The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia. Blood 2003;101:1698-704.
    • (2003) Blood , vol.101 , pp. 1698-1704
    • Ogawa, H.1    Tamaki, H.2    Ikegame, K.3
  • 16
    • 0033966369 scopus 로고    scopus 로고
    • + cytotoxic T-lymphocyte clone specific for WT1 peptide
    • + cytotoxic T-lymphocyte clone specific for WT1 peptide. Blood 2000;95:286-93.
    • (2000) Blood , vol.95 , pp. 286-293
    • Ohminami, H.1    Yasukawa, M.2    Fujita, S.3
  • 17
    • 0036217977 scopus 로고    scopus 로고
    • Lymphocyte-mediated cytotoxicity
    • Russell JH, Ley TJ. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 2002;20:323-70.
    • (2002) Annu Rev Immunol , vol.20 , pp. 323-370
    • Russell, J.H.1    Ley, T.J.2
  • 18
    • 0033562990 scopus 로고    scopus 로고
    • + CTL directed against herpes simplex virus-infected cells
    • + CTL directed against herpes simplex virus-infected cells. J Immunol 1999;162:6100-6.
    • (1999) J Immunol , vol.162 , pp. 6100-6106
    • Yasukawa, M.1    Ohminami, H.2    Yakushijin, Y.3
  • 20
    • 0037442238 scopus 로고    scopus 로고
    • + T lymphocytes: Analysis using the combination of hereditary perforin-deficient effector cells and Fas-deficient target cells
    • + T lymphocytes: analysis using the combination of hereditary perforin-deficient effector cells and Fas-deficient target cells. J Immunol 2003;170:2205-13.
    • (2003) J Immunol , vol.170 , pp. 2205-2213
    • Yanai, F.1    Ishii, E.2    Kojima, K.3
  • 21
    • 0036177505 scopus 로고    scopus 로고
    • Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes
    • Azuma T, Makita M, Ninomiya K, et al. Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes. Br J Haematol 2002;116:601-3.
    • (2002) Br J Haematol , vol.116 , pp. 601-603
    • Azuma, T.1    Makita, M.2    Ninomiya, K.3
  • 23
    • 0036023425 scopus 로고    scopus 로고
    • Antilung cancer effect of WT1-specific cytotoxic T lymphocytes
    • Makita M, Hiraki A, Azuma T, et al. Antilung cancer effect of WT1-specific cytotoxic T lymphocytes. Clin Cancer Res 2002;8:2626-31.
    • (2002) Clin Cancer Res , vol.8 , pp. 2626-2631
    • Makita, M.1    Hiraki, A.2    Azuma, T.3
  • 24
    • 0030569503 scopus 로고    scopus 로고
    • Human perform: Rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays
    • Froelich CJ, Turbov J, Hanna W. Human perform: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays. Biochem Biophys Res Commun 1996;229:44-9.
    • (1996) Biochem Biophys Res Commun , vol.229 , pp. 44-49
    • Froelich, C.J.1    Turbov, J.2    Hanna, W.3
  • 25
    • 10544252275 scopus 로고    scopus 로고
    • New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis
    • Froelich CJ, Orth K, Turbov J, et al. New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis. J Biol Chem 1996;271:29073-9.
    • (1996) J Biol Chem , vol.271 , pp. 29073-29079
    • Froelich, C.J.1    Orth, K.2    Turbov, J.3
  • 26
    • 0023912243 scopus 로고
    • + human cytotoxic T cell clones directed against herpes simplex virus
    • + human cytotoxic T cell clones directed against herpes simplex virus. J Immunol 1988;140:3419-25.
    • (1988) J Immunol , vol.140 , pp. 3419-3425
    • Yasukawa, M.1    Inatsuki, A.2    Kobayashi, Y.3
  • 27
    • 0030005837 scopus 로고    scopus 로고
    • Concanamycin A, a powerful tool for characterization and estimation of contribution of perform- and Fas-based lytic pathways in cell-mediated cytotoxicity
    • Kataoka T, Shinohara N, Takamiya H, et al. Concanamycin A, a powerful tool for characterization and estimation of contribution of perform- and Fas-based lytic pathways in cell-mediated cytotoxicity. J Immunol 1996;156:3678-86.
    • (1996) J Immunol , vol.156 , pp. 3678-3686
    • Kataoka, T.1    Shinohara, N.2    Takamiya, H.3
  • 28
    • 0035885950 scopus 로고    scopus 로고
    • + T-cell epitopes by a computer algorithm and an enzyme-linked immunospot assay
    • + T-cell epitopes by a computer algorithm and an enzyme-linked immunospot assay. Blood 2001;98:1872-81.
    • (2001) Blood , vol.98 , pp. 1872-1881
    • Kuzushima, K.1    Hayashi, N.2    Kimura, H.3    Tsurumi, T.4
  • 29
    • 0030030950 scopus 로고    scopus 로고
    • Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes
    • Lowin B, Mattman C, Hahne M, Tschopp J. Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes. Int Immunol 1996;8:57-63.
    • (1996) Int Immunol , vol.8 , pp. 57-63
    • Lowin, B.1    Mattman, C.2    Hahne, M.3    Tschopp, J.4
  • 30
    • 0032523810 scopus 로고    scopus 로고
    • Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia
    • Yotnda P, Firat H, Garcia-Pons F, et al. Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia. J Clin Investig 1998;101:2290-6.
    • (1998) J Clin Investig , vol.101 , pp. 2290-2296
    • Yotnda, P.1    Firat, H.2    Garcia-Pons, F.3
  • 31
    • 0032005138 scopus 로고    scopus 로고
    • + T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia
    • + T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia. Blood 1998;91:977-83.
    • (1998) Blood , vol.91 , pp. 977-983
    • Nieda, M.1    Nicol, A.2    Kikuchi, A.3
  • 32
    • 0035892131 scopus 로고    scopus 로고
    • Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein
    • Clark RE, Dodi A, Hill SC, et al. Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein. Blood 2001;98:2887-93.
    • (2001) Blood , vol.98 , pp. 2887-2893
    • Clark, R.E.1    Dodi, A.2    Hill, S.C.3
  • 33
    • 0032213388 scopus 로고    scopus 로고
    • + cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner
    • + cytotoxic T-cell clones specific for bcr-abl b3a2 fusion peptide augment colony formation by chronic myelogenous leukemia cells in a b3a2-specific and HLA-DR-restricted manner. Blood 1998;92:3355-61.
    • (1998) Blood , vol.92 , pp. 3355-3361
    • Yasukawa, M.1    Ohminami, H.2    Kaneko, S.3
  • 36
    • 0032527907 scopus 로고    scopus 로고
    • Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia
    • Yotnda P, Garcia F, Peuchmaur M, et al. Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia. J Clin Investig 1998;102:455-62.
    • (1998) J Clin Investig , vol.102 , pp. 455-462
    • Yotnda, P.1    Garcia, F.2    Peuchmaur, M.3
  • 37
    • 0030176270 scopus 로고    scopus 로고
    • Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
    • Sykulev Y, Joo M, Vturina I, Tsomides TJ, Eisen HN. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 1996;4:565-71.
    • (1996) Immunity , vol.4 , pp. 565-571
    • Sykulev, Y.1    Joo, M.2    Vturina, I.3    Tsomides, T.J.4    Eisen, H.N.5
  • 38
    • 0025157629 scopus 로고
    • Resistance of cytolytic lymphocytes to perforin-mediated killing. Inhibition of perform binding activity by surface membrane proteins
    • Jiang SB, Ojcius DM, Persechini PM, Young JD. Resistance of cytolytic lymphocytes to perforin-mediated killing. Inhibition of perform binding activity by surface membrane proteins. J Immunol 1990;144:998-1003.
    • (1990) J Immunol , vol.144 , pp. 998-1003
    • Jiang, S.B.1    Ojcius, D.M.2    Persechini, P.M.3    Young, J.D.4
  • 39
    • 0027968994 scopus 로고
    • Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perform
    • Muller C, Tschopp J. Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perform. J Immunol 1994;153:2470-8.
    • (1994) J Immunol , vol.153 , pp. 2470-2478
    • Muller, C.1    Tschopp, J.2
  • 40
    • 0037136311 scopus 로고    scopus 로고
    • Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation
    • Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA. Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. J Exp Med 2002;196:493-503.
    • (2002) J Exp Med , vol.196 , pp. 493-503
    • Balaji, K.N.1    Schaschke, N.2    Machleidt, W.3    Catalfamo, M.4    Henkart, P.A.5
  • 41
    • 0031792776 scopus 로고    scopus 로고
    • Selective regulation of apoptosis: The cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway
    • Bird CH, Sutton VR, Sun J, et al. Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. Mol Cell Biol 1998;18:6387-98.
    • (1998) Mol Cell Biol , vol.18 , pp. 6387-6398
    • Bird, C.H.1    Sutton, V.R.2    Sun, J.3
  • 42
    • 0345269959 scopus 로고    scopus 로고
    • The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins
    • Odeberg J, Browne H, Metkar S, et al. The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins. J Virol 2003;77:4539-45.
    • (2003) J Virol , vol.77 , pp. 4539-4545
    • Odeberg, J.1    Browne, H.2    Metkar, S.3
  • 43
    • 0034661878 scopus 로고    scopus 로고
    • Impaired binding of perform on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells
    • Lehmann C, Zeis M, Schmitz N, Uharek L. Impaired binding of perform on the surface of tumor cells is a cause of target cell resistance against cytotoxic effector cells. Blood 2000;96:594-600.
    • (2000) Blood , vol.96 , pp. 594-600
    • Lehmann, C.1    Zeis, M.2    Schmitz, N.3    Uharek, L.4
  • 44
    • 0035313542 scopus 로고    scopus 로고
    • Flow cytometry cannot assess surface binding of perform to target cells
    • Metkar SS, Aguilar-Santelises M, Wang B, Froelich CJ. Flow cytometry cannot assess surface binding of perform to target cells. Blood 2001;97:2181-3.
    • (2001) Blood , vol.97 , pp. 2181-2183
    • Metkar, S.S.1    Aguilar-Santelises, M.2    Wang, B.3    Froelich, C.J.4
  • 46
    • 0034025657 scopus 로고    scopus 로고
    • Vaccination of multiple myeloma patients with idiotype-pulsed dendritic cells: Immunological and clinical aspects
    • Titzer S, Christensen O, Manzke O, et al. Vaccination of multiple myeloma patients with idiotype-pulsed dendritic cells: immunological and clinical aspects. Br J Haematol 2000;108:805-16.
    • (2000) Br J Haematol , vol.108 , pp. 805-816
    • Titzer, S.1    Christensen, O.2    Manzke, O.3
  • 47
    • 0037804767 scopus 로고    scopus 로고
    • Idiotype vaccination in multiple myeloma induced a reduction of circulating clonal tumor B cells
    • Rasmussen T, Hansson L, Osterborg A, Johnsen HE, Mellstedt H. Idiotype vaccination in multiple myeloma induced a reduction of circulating clonal tumor B cells. Blood 2003;101:4607-10.
    • (2003) Blood , vol.101 , pp. 4607-4610
    • Rasmussen, T.1    Hansson, L.2    Osterborg, A.3    Johnsen, H.E.4    Mellstedt, H.5
  • 48
    • 0030996555 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes derived from bone marrow mononuclear cells of multiple myeloma patients recognize an underglycosylated form of MUC1 mucin
    • Noto H, Takahashi T, Makiguchi Y, et al. Cytotoxic T lymphocytes derived from bone marrow mononuclear cells of multiple myeloma patients recognize an underglycosylated form of MUC1 mucin. Int Immunol 1997;9:791-8.
    • (1997) Int Immunol , vol.9 , pp. 791-798
    • Noto, H.1    Takahashi, T.2    Makiguchi, Y.3
  • 49
    • 0036683378 scopus 로고    scopus 로고
    • Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma
    • Chiriva-Internati M, Wang Z, Salati E, et al. Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma. Blood 2002;100:961-5.
    • (2002) Blood , vol.100 , pp. 961-965
    • Chiriva-Internati, M.1    Wang, Z.2    Salati, E.3
  • 50
    • 0035282736 scopus 로고    scopus 로고
    • Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma
    • Lim SH, Wang Z, Chiriva-Intemati M, Xue Y. Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma. Blood 2001;97:1508-10.
    • (2001) Blood , vol.97 , pp. 1508-1510
    • Lim, S.H.1    Wang, Z.2    Chiriva-Intemati, M.3    Xue, Y.4
  • 51
    • 0037305646 scopus 로고    scopus 로고
    • Gene expression and immunologic consequence of SPAN-Xb in myeloma and other hematologic malignancies
    • Wang Z, Zhang Y, Liu H, et al. Gene expression and immunologic consequence of SPAN-Xb in myeloma and other hematologic malignancies. Blood 2003;101:955-60.
    • (2003) Blood , vol.101 , pp. 955-960
    • Wang, Z.1    Zhang, Y.2    Liu, H.3
  • 52
    • 0033567078 scopus 로고    scopus 로고
    • Genes encoding tumor-specific antigens are expressed in human myeloma cells
    • van Baren N, Brasseur F, Godelaine D, et al. Genes encoding tumor-specific antigens are expressed in human myeloma cells. Blood 1999;94:1156-64.
    • (1999) Blood , vol.94 , pp. 1156-1164
    • Van Baren, N.1    Brasseur, F.2    Godelaine, D.3
  • 53
    • 0037219618 scopus 로고    scopus 로고
    • Tumour-associated antigens in multiple myeloma
    • Pellat-Deceunynck C. Tumour-associated antigens in multiple myeloma. Br J Haematol 2003;120:3-9.
    • (2003) Br J Haematol , vol.120 , pp. 3-9
    • Pellat-Deceunynck, C.1


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