Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes

British Journal of Haematology

Volumn 116, Issue 3, 2002, Pages 601-603

  Yasukawa, Masaki ^a   Fujita, Shigeru ^a   Makita, Masanori ^a   Azuma, Taichi ^a   Harada, Mine ^b  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Cytotoxic T lymphocytes; Dendritic cells; HLA; Immunotherapy; WT1

Indexed keywords

ANTILEUKEMIC AGENT; ARGINYLTRYPTOPHYLPROLYLSERYLCYSTEINYLGLUTAMINYLLYSYLLYSYLPHENYLALANINE; CD8 ANTIGEN; CYSTEINYLMETHIONYLTHREONYLTRYPTOPHYLASPARAGINYLGLUTAMINYLMETHIONYLASPARAGIN YLLEUCINE; EPITOPE; HLA A ANTIGEN; HUMAN LEUKOCYTE ANTIGEN A24; PEPTIDE; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; HUMAN; HUMAN CELL; LEUKEMIA; NEPHROBLASTOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; T LYMPHOCYTE;

CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; HLA-A ANTIGENS; HUMANS; LEUKEMIA; TUMOR CELLS, CULTURED; WT1 PROTEINS;

EID: 0036177505     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0007-1048.2001.03329.x     Document Type: Article

References (12)

1. Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes
2. + progenitor cells by cytotoxic T lymphocytes specific for WT1
3. A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A-24-restricted and tumor-specific CTLs
4. Aberrant over-expression of the Wilms tumor gene (WT1) in human leukemia
5. Quantitative monitoring of the PRAME gene for the detection of minimal residual disease in leukaemia
6. Targeted T-cell therapy for human leukemia: Cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells
7. + T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia
8. + cytotoxic T-lymphocyte clone specific for WT1 peptide
9. Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth
10. Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1) product
11. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes
12. Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia