-
1
-
-
0029939467
-
Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system
-
Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 1996, 85:299-302.
-
(1996)
Cell
, vol.85
, pp. 299-302
-
-
Steinman, L.1
-
2
-
-
65249142200
-
The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?
-
Weiner HL. The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?. Ann Neurol 2009, 65:239-248.
-
(2009)
Ann Neurol
, vol.65
, pp. 239-248
-
-
Weiner, H.L.1
-
3
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R, Linington C, Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 2006, 129:1953-1971.
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
4
-
-
0029420666
-
Early treatment trials with interferon beta in multiple sclerosis
-
Panitch HS. Early treatment trials with interferon beta in multiple sclerosis. Mult Scler 1995, 1(Suppl 1):S17-21.
-
(1995)
Mult Scler
, vol.1
, Issue.SUPPL. 1
-
-
Panitch, H.S.1
-
6
-
-
34547108380
-
JAK-STAT signaling: from interferons to cytokines
-
Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 2007, 282:20059-20063.
-
(2007)
J Biol Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
7
-
-
19944366634
-
Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection
-
Ousman SS, Wang J, Campbell IL. Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection. J Virol 2005, 79:7514-7527.
-
(2005)
J Virol
, vol.79
, pp. 7514-7527
-
-
Ousman, S.S.1
Wang, J.2
Campbell, I.L.3
-
8
-
-
77955499638
-
Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System
-
Khorooshi R, Owens T. Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System. J Immunol 2010,
-
(2010)
J Immunol
-
-
Khorooshi, R.1
Owens, T.2
-
9
-
-
32644456874
-
Antiviral innate immunity pathways
-
Seth RB, Sun L, Chen ZJ. Antiviral innate immunity pathways. Cell Res 2006, 16:141-147.
-
(2006)
Cell Res
, vol.16
, pp. 141-147
-
-
Seth, R.B.1
Sun, L.2
Chen, Z.J.3
-
10
-
-
27744526416
-
Regulation of the type I IFN induction: a current view
-
Honda K, Yanai H, Takaoka A, Taniguchi T. Regulation of the type I IFN induction: a current view. Int Immunol 2005, 17:1367-1378.
-
(2005)
Int Immunol
, vol.17
, pp. 1367-1378
-
-
Honda, K.1
Yanai, H.2
Takaoka, A.3
Taniguchi, T.4
-
11
-
-
17144404177
-
IRF-7 is the master regulator of type-I interferon-dependent immune responses
-
Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434:772-777.
-
(2005)
Nature
, vol.434
, pp. 772-777
-
-
Honda, K.1
Yanai, H.2
Negishi, H.3
Asagiri, M.4
Sato, M.5
Mizutani, T.6
Shimada, N.7
Ohba, Y.8
Takaoka, A.9
Yoshida, N.10
Taniguchi, T.11
-
12
-
-
38449100329
-
Type I interferons as anti-inflammatory mediators
-
Benveniste EN, Qin H. Type I interferons as anti-inflammatory mediators. Sci STKE 2007, 2007:pe70.
-
(2007)
Sci STKE
, vol.2007
-
-
Benveniste, E.N.1
Qin, H.2
-
13
-
-
43049177588
-
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
-
Prinz M, Schmidt H, Mildner A, Knobeloch KP, Hanisch UK, Raasch J, Merkler D, Detje C, Gutcher I, Mages J, Lang R, Martin R, Gold R, Becher B, Bruck W, Kalinke U. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008, 28:675-686.
-
(2008)
Immunity
, vol.28
, pp. 675-686
-
-
Prinz, M.1
Schmidt, H.2
Mildner, A.3
Knobeloch, K.P.4
Hanisch, U.K.5
Raasch, J.6
Merkler, D.7
Detje, C.8
Gutcher, I.9
Mages, J.10
Lang, R.11
Martin, R.12
Gold, R.13
Becher, B.14
Bruck, W.15
Kalinke, U.16
-
14
-
-
0037407587
-
IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis
-
Teige I, Treschow A, Teige A, Mattsson R, Navikas V, Leanderson T, Holmdahl R, Issazadeh-Navikas S. IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis. J Immunol 2003, 170:4776-4784.
-
(2003)
J Immunol
, vol.170
, pp. 4776-4784
-
-
Teige, I.1
Treschow, A.2
Teige, A.3
Mattsson, R.4
Navikas, V.5
Leanderson, T.6
Holmdahl, R.7
Issazadeh-Navikas, S.8
-
15
-
-
78650077560
-
Interferon-beta is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis
-
Galligan CL, Pennell LM, Murooka TT, Baig E, Majchrzak-Kita B, Rahbar R, Fish EN. Interferon-beta is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis. Mult Scler 2010, 16:1458-1473.
-
(2010)
Mult Scler
, vol.16
, pp. 1458-1473
-
-
Galligan, C.L.1
Pennell, L.M.2
Murooka, T.T.3
Baig, E.4
Majchrzak-Kita, B.5
Rahbar, R.6
Fish, E.N.7
-
16
-
-
33646719699
-
Neurons produce type I interferon during viral encephalitis
-
Delhaye S, Paul S, Blakqori G, Minet M, Weber F, Staeheli P, Michiels T. Neurons produce type I interferon during viral encephalitis. Proc Natl Acad Sci USA 2006, 103:7835-7840.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7835-7840
-
-
Delhaye, S.1
Paul, S.2
Blakqori, G.3
Minet, M.4
Weber, F.5
Staeheli, P.6
Michiels, T.7
-
17
-
-
27744476769
-
Exploiting genotypic differences to identify genes important for EAE development
-
Jelinsky SA, Miyashiro JS, Saraf KA, Tunkey C, Reddy P, Newcombe J, Oestreicher JL, Brown E, Trepicchio WL, Leonard JP, Marusic S. Exploiting genotypic differences to identify genes important for EAE development. J Neurol Sci 2005, 239:81-93.
-
(2005)
J Neurol Sci
, vol.239
, pp. 81-93
-
-
Jelinsky, S.A.1
Miyashiro, J.S.2
Saraf, K.A.3
Tunkey, C.4
Reddy, P.5
Newcombe, J.6
Oestreicher, J.L.7
Brown, E.8
Trepicchio, W.L.9
Leonard, J.P.10
Marusic, S.11
-
18
-
-
78349263043
-
Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease
-
Toft-Hansen H, Fuchtbauer L, Owens T. Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease. Glia 2011, 59:166-176.
-
(2011)
Glia
, vol.59
, pp. 166-176
-
-
Toft-Hansen, H.1
Fuchtbauer, L.2
Owens, T.3
-
19
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005, 17:1-14.
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
20
-
-
43049101640
-
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
-
Guo B, Chang EY, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest 2008, 118:1680-1690.
-
(2008)
J Clin Invest
, vol.118
, pp. 1680-1690
-
-
Guo, B.1
Chang, E.Y.2
Cheng, G.3
-
21
-
-
32444443739
-
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis
-
Prinz M, Garbe F, Schmidt H, Mildner A, Gutcher I, Wolter K, Piesche M, Schroers R, Weiss E, Kirschning CJ, Rochford CD, Bruck W, Becher B. Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest 2006, 116:456-464.
-
(2006)
J Clin Invest
, vol.116
, pp. 456-464
-
-
Prinz, M.1
Garbe, F.2
Schmidt, H.3
Mildner, A.4
Gutcher, I.5
Wolter, K.6
Piesche, M.7
Schroers, R.8
Weiss, E.9
Kirschning, C.J.10
Rochford, C.D.11
Bruck, W.12
Becher, B.13
-
22
-
-
33748475531
-
Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
-
Honda K, Takaoka A, Taniguchi T. Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 2006, 25:349-360.
-
(2006)
Immunity
, vol.25
, pp. 349-360
-
-
Honda, K.1
Takaoka, A.2
Taniguchi, T.3
-
23
-
-
0028964995
-
Modification of acute experimental autoimmune encephalomyelitis in the Lewis rat by oral administration of type 1 interferons
-
Brod SA, Scott M, Burns DK, Phillips JT. Modification of acute experimental autoimmune encephalomyelitis in the Lewis rat by oral administration of type 1 interferons. J Interferon Cytokine Res 1995, 15:115-122.
-
(1995)
J Interferon Cytokine Res
, vol.15
, pp. 115-122
-
-
Brod, S.A.1
Scott, M.2
Burns, D.K.3
Phillips, J.T.4
-
24
-
-
0033544319
-
Interferon beta induces T-helper 2 immune deviation in MS
-
Kozovska ME, Hong J, Zang YC, Li S, Rivera VM, Killian JM, Zhang JZ. Interferon beta induces T-helper 2 immune deviation in MS. Neurology 1999, 53:1692-1697.
-
(1999)
Neurology
, vol.53
, pp. 1692-1697
-
-
Kozovska, M.E.1
Hong, J.2
Zang, Y.C.3
Li, S.4
Rivera, V.M.5
Killian, J.M.6
Zhang, J.Z.7
-
25
-
-
0030589314
-
The length of treatment determines whether IFN-beta prevents or aggravates experimental autoimmune encephalomyelitis in Lewis rats
-
Ruuls SR, de Labie MC, Weber KS, Botman CA, Groenestein RJ, Dijkstra CD, Olsson T, van der Meide PH. The length of treatment determines whether IFN-beta prevents or aggravates experimental autoimmune encephalomyelitis in Lewis rats. J Immunol 1996, 157:5721-5731.
-
(1996)
J Immunol
, vol.157
, pp. 5721-5731
-
-
Ruuls, S.R.1
de Labie, M.C.2
Weber, K.S.3
Botman, C.A.4
Groenestein, R.J.5
Dijkstra, C.D.6
Olsson, T.7
van der Meide, P.H.8
-
26
-
-
0032053599
-
Discontinuation of treatment with IFN-beta leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats
-
van der Meide PH, de Labie MC, Ruuls SR, Groenestein RJ, Botman CA, Olsson T, Dijkstra CD. Discontinuation of treatment with IFN-beta leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats. Rapid reversal of the antiproliferative activity of IFN-beta and excessive expansion of autoreactive T cells as disease promoting mechanisms. J Neuroimmunol 1998, 84:14-23.
-
(1998)
Rapid reversal of the antiproliferative activity of IFN-beta and excessive expansion of autoreactive T cells as disease promoting mechanisms. J Neuroimmunol
, vol.84
, pp. 14-23
-
-
van der Meide, P.H.1
de Labie, M.C.2
Ruuls, S.R.3
Groenestein, R.J.4
Botman, C.A.5
Olsson, T.6
Dijkstra, C.D.7
-
27
-
-
0041319041
-
Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
-
Babcock AA, Kuziel WA, Rivest S, Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci 2003, 23:7922-7930.
-
(2003)
J Neurosci
, vol.23
, pp. 7922-7930
-
-
Babcock, A.A.1
Kuziel, W.A.2
Rivest, S.3
Owens, T.4
-
28
-
-
58149182884
-
NF-kappaB-driven STAT2 and CCL2 expression in astrocytes in response to brain injury
-
Khorooshi R, Babcock AA, Owens T. NF-kappaB-driven STAT2 and CCL2 expression in astrocytes in response to brain injury. J Immunol 2008, 181:7284-7291.
-
(2008)
J Immunol
, vol.181
, pp. 7284-7291
-
-
Khorooshi, R.1
Babcock, A.A.2
Owens, T.3
-
30
-
-
0037307911
-
IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells
-
Lande R, Giacomini E, Grassi T, Remoli ME, Iona E, Miettinen M, Julkunen I, Coccia EM. IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells. J Immunol 2003, 170:1174-1182.
-
(2003)
J Immunol
, vol.170
, pp. 1174-1182
-
-
Lande, R.1
Giacomini, E.2
Grassi, T.3
Remoli, M.E.4
Iona, E.5
Miettinen, M.6
Julkunen, I.7
Coccia, E.M.8
-
31
-
-
38649126543
-
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion
-
Zhai Y, Qiao B, Gao F, Shen X, Vardanian A, Busuttil RW, Kupiec-Weglinski JW. Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion. Hepatology 2008, 47:199-206.
-
(2008)
Hepatology
, vol.47
, pp. 199-206
-
-
Zhai, Y.1
Qiao, B.2
Gao, F.3
Shen, X.4
Vardanian, A.5
Busuttil, R.W.6
Kupiec-Weglinski, J.W.7
-
32
-
-
35448988886
-
Interferon-beta is neuroprotective against the toxicity induced by activated microglia
-
Jin S, Kawanokuchi J, Mizuno T, Wang J, Sonobe Y, Takeuchi H, Suzumura A. Interferon-beta is neuroprotective against the toxicity induced by activated microglia. Brain Res 2007, 1179:140-146.
-
(2007)
Brain Res
, vol.1179
, pp. 140-146
-
-
Jin, S.1
Kawanokuchi, J.2
Mizuno, T.3
Wang, J.4
Sonobe, Y.5
Takeuchi, H.6
Suzumura, A.7
-
33
-
-
35349024802
-
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system
-
Muller M, Carter SL, Hofer MJ, Manders P, Getts DR, Getts MT, Dreykluft A, Lu B, Gerard C, King NJ, Campbell IL. CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J Immunol 2007, 179:2774-2786.
-
(2007)
J Immunol
, vol.179
, pp. 2774-2786
-
-
Muller, M.1
Carter, S.L.2
Hofer, M.J.3
Manders, P.4
Getts, D.R.5
Getts, M.T.6
Dreykluft, A.7
Lu, B.8
Gerard, C.9
King, N.J.10
Campbell, I.L.11
-
34
-
-
0035911254
-
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
-
Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med 2001, 193:713-726.
-
(2001)
J Exp Med
, vol.193
, pp. 713-726
-
-
Huang, D.R.1
Wang, J.2
Kivisakk, P.3
Rollins, B.J.4
Ransohoff, R.M.5
-
35
-
-
33646045379
-
CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system
-
Christensen JE, de Lemos C, Moos T, Christensen JP, Thomsen AR. CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system. J Immunol 2006, 176:4235-4243.
-
(2006)
J Immunol
, vol.176
, pp. 4235-4243
-
-
Christensen, J.E.1
de Lemos, C.2
Moos, T.3
Christensen, J.P.4
Thomsen, A.R.5
-
36
-
-
0036270888
-
Interferon-beta directly influences monocyte infiltration into the central nervous system
-
Floris S, Ruuls SR, Wierinckx A, van der Pol SM, Dopp E, van der Meide PH, Dijkstra CD, De Vries HE. Interferon-beta directly influences monocyte infiltration into the central nervous system. J Neuroimmunol 2002, 127:69-79.
-
(2002)
J Neuroimmunol
, vol.127
, pp. 69-79
-
-
Floris, S.1
Ruuls, S.R.2
Wierinckx, A.3
van der Pol, S.M.4
Dopp, E.5
van der Meide, P.H.6
Dijkstra, C.D.7
De Vries, H.E.8
-
37
-
-
0031471371
-
Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9
-
Stuve O, Chabot S, Jung SS, Williams G, Yong VW. Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9. J Neuroimmunol 1997, 80:38-46.
-
(1997)
J Neuroimmunol
, vol.80
, pp. 38-46
-
-
Stuve, O.1
Chabot, S.2
Jung, S.S.3
Williams, G.4
Yong, V.W.5
-
38
-
-
3042694846
-
Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment
-
Liuzzi GM, Latronico T, Fasano A, Carlone G, Riccio P. Interferon-beta inhibits the expression of metalloproteinases in rat glial cell cultures: implications for multiple sclerosis pathogenesis and treatment. Mult Scler 2004, 10:290-297.
-
(2004)
Mult Scler
, vol.10
, pp. 290-297
-
-
Liuzzi, G.M.1
Latronico, T.2
Fasano, A.3
Carlone, G.4
Riccio, P.5
-
39
-
-
34248137873
-
APC-derived cytokines and T cell polarization in autoimmune inflammation
-
Gutcher I, Becher B. APC-derived cytokines and T cell polarization in autoimmune inflammation. J Clin Invest 2007, 117:1119-1127.
-
(2007)
J Clin Invest
, vol.117
, pp. 1119-1127
-
-
Gutcher, I.1
Becher, B.2
-
40
-
-
33846966636
-
A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 2007, 13:139-145.
-
(2007)
Nat Med
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
41
-
-
61749093508
-
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice
-
Haak S, Croxford AL, Kreymborg K, Heppner FL, Pouly S, Becher B, Waisman A. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest 2009, 119:61-69.
-
(2009)
J Clin Invest
, vol.119
, pp. 61-69
-
-
Haak, S.1
Croxford, A.L.2
Kreymborg, K.3
Heppner, F.L.4
Pouly, S.5
Becher, B.6
Waisman, A.7
-
42
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama Y, Nakae S, Matsuki T, Nambu A, Ishigame H, Kakuta S, Sudo K, Iwakura Y. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 2006, 177:566-573.
-
(2006)
J Immunol
, vol.177
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
Nambu, A.4
Ishigame, H.5
Kakuta, S.6
Sudo, K.7
Iwakura, Y.8
-
43
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 2008, 14:337-342.
-
(2008)
Nat Med
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
44
-
-
79960219135
-
IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells
-
Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM. IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells. Brain Behav Immun 2011,
-
(2011)
Brain Behav Immun
-
-
Sweeney, C.M.1
Lonergan, R.2
Basdeo, S.A.3
Kinsella, K.4
Dungan, L.S.5
Higgins, S.C.6
Kelly, P.J.7
Costelloe, L.8
Tubridy, N.9
Mills, K.H.10
Fletcher, J.M.11
-
45
-
-
0032080850
-
Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development
-
McRae BL, Semnani RT, Hayes MP, van Seventer GA. Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development. J Immunol 1998, 160:4298-4304.
-
(1998)
J Immunol
, vol.160
, pp. 4298-4304
-
-
McRae, B.L.1
Semnani, R.T.2
Hayes, M.P.3
van Seventer, G.A.4
-
46
-
-
77950534540
-
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
-
Axtell RC, de Jong BA, Boniface K, van der Voort LF, Bhat R, De Sarno P, Naves R, Han M, Zhong F, Castellanos JG, Mair R, Christakos A, Kolkowitz I, Katz L, Killestein J, Polman CH, de Waal Malefyt R, Steinman L, Raman C. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat Med 2010, 16:406-412.
-
(2010)
Nat Med
, vol.16
, pp. 406-412
-
-
Axtell, R.C.1
de Jong, B.A.2
Boniface, K.3
van der Voort, L.F.4
Bhat, R.5
De Sarno, P.6
Naves, R.7
Han, M.8
Zhong, F.9
Castellanos, J.G.10
Mair, R.11
Christakos, A.12
Kolkowitz, I.13
Katz, L.14
Killestein, J.15
Polman, C.H.16
de Waal Malefyt, R.17
Steinman, L.18
Raman, C.19
-
47
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
48
-
-
45249112573
-
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
-
Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, Gustafsdottir SM, Sigurdsson S, Lundmark A, Tienari PJ, Koivisto K, Elovaara I, Pirttila T, Reunanen M, Peltonen L, Saarela J, Hillert J, Olsson T, Landegren U, Alcina A, Fernandez O, Leyva L, Guerrero M, Lucas M, Izquierdo G, Matesanz F, Syvanen AC. Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet 2008, 45:362-369.
-
(2008)
J Med Genet
, vol.45
, pp. 362-369
-
-
Kristjansdottir, G.1
Sandling, J.K.2
Bonetti, A.3
Roos, I.M.4
Milani, L.5
Wang, C.6
Gustafsdottir, S.M.7
Sigurdsson, S.8
Lundmark, A.9
Tienari, P.J.10
Koivisto, K.11
Elovaara, I.12
Pirttila, T.13
Reunanen, M.14
Peltonen, L.15
Saarela, J.16
Hillert, J.17
Olsson, T.18
Landegren, U.19
Alcina, A.20
Fernandez, O.21
Leyva, L.22
Guerrero, M.23
Lucas, M.24
Izquierdo, G.25
Matesanz, F.26
Syvanen, A.C.27
more..
-
49
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 2009, 41:776-782.
-
(2009)
Nat Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
de Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
Piccio, L.7
Raychaudhuri, S.8
Tran, D.9
Aubin, C.10
Briskin, R.11
Romano, S.12
Baranzini, S.E.13
McCauley, J.L.14
Pericak-Vance, M.A.15
Haines, J.L.16
Gibson, R.A.17
Naeglin, Y.18
Uitdehaag, B.19
Matthews, P.M.20
Kappos, L.21
Polman, C.22
McArdle, W.L.23
Strachan, D.P.24
Evans, D.25
Cross, A.H.26
Daly, M.J.27
Compston, A.28
Sawcer, S.J.29
Weiner, H.L.30
Hauser, S.L.31
Hafler, D.A.32
Oksenberg, J.R.33
more..
-
50
-
-
79953707345
-
Association of a functional IRF7 variant with systemic lupus erythematosus
-
Fu Q, Zhao J, Qian X, Wong JL, Kaufman KM, Yu CY, Mok MY, Harley JB, Guthridge JM, Song YW, Cho SK, Bae SC, Grossman JM, Hahn BH, Arnett FC, Shen N, Tsao BP. Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum 2011, 63:749-754.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 749-754
-
-
Fu, Q.1
Zhao, J.2
Qian, X.3
Wong, J.L.4
Kaufman, K.M.5
Yu, C.Y.6
Mok, M.Y.7
Harley, J.B.8
Guthridge, J.M.9
Song, Y.W.10
Cho, S.K.11
Bae, S.C.12
Grossman, J.M.13
Hahn, B.H.14
Arnett, F.C.15
Shen, N.16
Tsao, B.P.17
|