Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 1, 2012, Pages 152-160

  Kaszas, Krisztian ^a   Keller, Jason M ^a   Coddou, Claudio ^b   Mishra, Santosh K ^a   Hoon, Mark A ^a   Stojilkovic, Stanko ^b   Jacobson, Kenneth A ^c   Iadarola, Michael J ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,5 DIETHYL 3 (2 METHOXYETHYLTHIO) 2 METHYL 6 PHENYL 1,4 DIHYDROPYRIDINE 3,5 DICARBOXYLATE; CAPSAICIN; MRS 1477; PROTEIN KINASE C; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR AGONIST;

ACIDITY; ALLOSTERISM; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFICACY; DRUG POTENTIATION; DRUG SENSITIVITY; EMBRYO; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; BODY TEMPERATURE; CALCIUM; CALCIUM RADIOISOTOPES; CAPSAICIN; DIHYDROPYRIDINES; ELECTROPHYSIOLOGICAL PHENOMENA; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; PHOSPHORYLATION; PROTONS; RATS; SERINE; TRPV CATION CHANNELS;

EID: 84055219327     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.183053     Document Type: Article

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