Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist

Pain

Volumn 149, Issue 3, 2010, Pages 522-528

  Bates, Brian D ^a   Mitchell, Kendall ^a   Keller, Jason M ^a   Chan, Chi Chao ^b   Swaim, William D ^a   Yaskovich, Ruth ^a   Mannes, Andrew J ^a,c   Iadarola, Michael J ^a,c  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c CLINICAL CENTER   (United States)

Author keywords

C fibers; CGRP; Corneal pain; Eye wipe test; Ophthalmic analgesia; Resiniferatoxin; TRPV1; Vanilloid receptor 1; Wound healing

Indexed keywords

BETA TUBULIN; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; LIDOCAINE; RESINIFERATOXIN; VANILLOID RECEPTOR 1;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; CORNEA; CORNEA DISEASE; DOSE RESPONSE; DRUG RESPONSE; EYE PAIN; EYELID REFLEX; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCLERA; WOUND HEALING;

ADMINISTRATION, TOPICAL; ANALGESICS; ANIMALS; CORNEA; DISEASE MODELS, ANIMAL; DITERPENES; MALE; NOCICEPTORS; PAIN; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SENSORY RECEPTOR CELLS; TREATMENT OUTCOME; TRPV CATION CHANNELS;

EID: 77952099949     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2010.03.024     Document Type: Article

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