-
2
-
-
77953870112
-
Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People
-
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010; 39:412-423.
-
(2010)
Age Ageing
, vol.39
, pp. 412-423
-
-
Cruz-Jentoft, A.J.1
Baeyens, J.P.2
Bauer, J.M.3
Boirie, Y.4
Cederholm, T.5
Landi, F.6
Martin, F.C.7
Michel, J.P.8
Rolland, Y.9
Schneider, S.M.10
Topinkova, E.11
Vandewoude, M.12
Zamboni, M.13
-
3
-
-
79955142004
-
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia
-
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011; 12:249-256.
-
(2011)
J Am Med Dir Assoc
, vol.12
, pp. 249-256
-
-
Fielding, R.A.1
Vellas, B.2
Evans, W.J.3
Bhasin, S.4
Morley, J.E.5
Newman, A.B.6
Abellan van Kan, G.7
Andrieu, S.8
Bauer, J.9
Breuille, D.10
Cederholm, T.11
Chandler, J.12
De Meynard, C.13
Donini, L.14
Harris, T.15
Kannt, A.16
-
4
-
-
79958137426
-
Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training
-
Lenk K, Schuler G, Adams V. Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training. J Cachex Sarcopenia Muscle. 2010; 1:9-21.
-
(2010)
J Cachex Sarcopenia Muscle
, vol.1
, pp. 9-21
-
-
Lenk, K.1
Schuler, G.2
Adams, V.3
-
5
-
-
14644404350
-
Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia
-
Argiles JM, Busquets S, Felipe A, Lopez-Soriano FJ. Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia. Int J Biochem Cell Biol. 2005; 37:1084-1104.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 1084-1104
-
-
Argiles, J.M.1
Busquets, S.2
Felipe, A.3
Lopez-Soriano, F.J.4
-
6
-
-
5344258973
-
Adverse effects of thalidomide administration in patients with neoplastic diseases
-
Dimopoulos MA, Eleutherakis-Papaiakovou V. Adverse effects of thalidomide administration in patients with neoplastic diseases. Am J Med. 2004; 117:508-515.
-
(2004)
Am J Med
, vol.117
, pp. 508-515
-
-
Dimopoulos, M.A.1
Eleutherakis-Papaiakovou, V.2
-
8
-
-
34548732637
-
A placebo-controlled double blind trial of etanercept for the cancer anorexia/weight loss syndrome: results from N00C1 from the North Central Cancer Treatment Group
-
Jatoi A, Dakhil SR, Nguyen PL, Sloan JA, Kugler JW, Rowland KM, Jr., Soori GS, Wender DB, Fitch TR, Novotny PJ, Loprinzi CL. A placebo-controlled double blind trial of etanercept for the cancer anorexia/weight loss syndrome: results from N00C1 from the North Central Cancer Treatment Group. Cancer. 2007; 110:1396-1403.
-
(2007)
Cancer
, vol.110
, pp. 1396-1403
-
-
Jatoi, A.1
Dakhil, S.R.2
Nguyen, P.L.3
Sloan, J.A.4
Kugler, J.W.5
Rowland Jr., K.M.6
Soori, G.S.7
Wender, D.B.8
Fitch, T.R.9
Novotny, P.J.10
Loprinzi, C.L.11
-
9
-
-
38949086148
-
A multicenter, phase II study of infliximab plus gemcitabine in pancreatic cancer cachexia
-
Wiedenmann B, Malfertheiner P, Friess H, Ritch P, Arseneau J, Mantovani G, Caprioni F, Van Cutsem E, Richel D, DeWitte M, Qi M, Robinson D, Jr., Zhong B, De Boer C, Lu JD, Prabhakar U et al. A multicenter, phase II study of infliximab plus gemcitabine in pancreatic cancer cachexia. J Support Oncol. 2008; 6:18-25.
-
(2008)
J Support Oncol
, vol.6
, pp. 18-25
-
-
Wiedenmann, B.1
Malfertheiner, P.2
Friess, H.3
Ritch, P.4
Arseneau, J.5
Mantovani, G.6
Caprioni, F.7
Van Cutsem, E.8
Richel, D.9
DeWitte, M.10
Qi, M.11
Robinson Jr., D.12
Zhong, B.13
De Boer, C.14
Lu, J.D.15
Prabhakar, U.16
-
10
-
-
5444262078
-
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
-
Cai D, Frantz JD, Tawa NE, Jr., Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE. IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell. 2004; 119:285-298.
-
(2004)
Cell
, vol.119
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa Jr., N.E.3
Melendez, P.A.4
Oh, B.C.5
Lidov, H.G.6
Hasselgren, P.O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
11
-
-
0029921173
-
Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants
-
Buck M, Chojkier M. Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants. EMBO J. 1996; 15:1753-1765.
-
(1996)
EMBO J
, vol.15
, pp. 1753-1765
-
-
Buck, M.1
Chojkier, M.2
-
12
-
-
22544452988
-
NF-kappa B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release
-
Di Marco S, Mazroui R, Dallaire P, Chittur S, Tenenbaum SA, Radzioch D, Marette A, Gallouzi IE. NF-kappa B-mediated MyoD decay during muscle wasting requires nitric oxide synthase mRNA stabilization, HuR protein, and nitric oxide release. Mol Cell Biol. 2005; 25:6533-6545.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6533-6545
-
-
Di Marco, S.1
Mazroui, R.2
Dallaire, P.3
Chittur, S.4
Tenenbaum, S.A.5
Radzioch, D.6
Marette, A.7
Gallouzi, I.E.8
-
13
-
-
44149119740
-
Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice
-
Braga M, Sinha Hikim AP, Datta S, Ferrini MG, Brown D, Kovacheva EL, Gonzalez-Cadavid NF, Sinha-Hikim I. Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis. 2008; 13:822-832.
-
(2008)
Apoptosis
, vol.13
, pp. 822-832
-
-
Braga, M.1
Sinha Hikim, A.P.2
Datta, S.3
Ferrini, M.G.4
Brown, D.5
Kovacheva, E.L.6
Gonzalez-Cadavid, N.F.7
Sinha-Hikim, I.8
-
14
-
-
68049101141
-
Decreased Jun-D and myogenin expression in muscle wasting of human cachexia
-
Ramamoorthy S, Donohue M, Buck M. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Am J Physiol Endocrinol Metab. 2009; 297:E392-401.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
-
-
Ramamoorthy, S.1
Donohue, M.2
Buck, M.3
-
15
-
-
0030968884
-
Sarcopenia: origins and clinical relevance
-
Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr. 1997; 127:990S-991S.
-
(1997)
J Nutr
, vol.127
-
-
Rosenberg, I.H.1
-
16
-
-
70350490534
-
Towards a definition of sarcopenia-results from epidemiologic studies
-
Visser M. Towards a definition of sarcopenia-results from epidemiologic studies. J Nutr Health Aging. 2009; 13:713-716.
-
(2009)
J Nutr Health Aging
, vol.13
, pp. 713-716
-
-
Visser, M.1
-
17
-
-
0032522560
-
Epidemiology of sarcopenia among the elderly in New Mexico
-
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998; 147:755-763.
-
(1998)
Am J Epidemiol
, vol.147
, pp. 755-763
-
-
Baumgartner, R.N.1
Koehler, K.M.2
Gallagher, D.3
Romero, L.4
Heymsfield, S.B.5
Ross, R.R.6
Garry, P.J.7
Lindeman, R.D.8
-
18
-
-
0036904691
-
Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women
-
Iannuzzi-Sucich M, Prestwood KM, Kenny AM. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. J Gerontol A Biol Sci Med Sci. 2002; 57:M772-777.
-
(2002)
J Gerontol A Biol Sci Med Sci
, vol.57
-
-
Iannuzzi-Sucich, M.1
Prestwood, K.M.2
Kenny, A.M.3
-
19
-
-
0035028863
-
Kinetics of human aging: I. Rates of senescence between ages 30 and 70 years in healthy people
-
Sehl ME, Yates FE. Kinetics of human aging: I. Rates of senescence between ages 30 and 70 years in healthy people. J Gerontol A Biol Sci Med Sci. 2001; 56:B198-208.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Sehl, M.E.1
Yates, F.E.2
-
20
-
-
34547134453
-
Frailty in older men: prevalence, progression, and relationship with mortality
-
Cawthon PM, Marshall LM, Michael Y, Dam TT, Ensrud KE, Barrett-Connor E, Orwoll ES. Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc. 2007; 55:1216-1223.
-
(2007)
J Am Geriatr Soc
, vol.55
, pp. 1216-1223
-
-
Cawthon, P.M.1
Marshall, L.M.2
Michael, Y.3
Dam, T.T.4
Ensrud, K.E.5
Barrett-Connor, E.6
Orwoll, E.S.7
-
21
-
-
77649204142
-
Sarcopenia-mechanisms and treatments
-
Jones TE, Stephenson KW, King JG, Knight KR, Marshall TL, Scott WB. Sarcopenia-mechanisms and treatments. J Geriatr Phys Ther. 2009; 32:83-89.
-
(2009)
J Geriatr Phys Ther
, vol.32
, pp. 83-89
-
-
Jones, T.E.1
Stephenson, K.W.2
King, J.G.3
Knight, K.R.4
Marshall, T.L.5
Scott, W.B.6
-
22
-
-
77953745513
-
Molecular mechanisms in aging and current strategies to counteract sarcopenia
-
Sakuma K, Yamaguchi A. Molecular mechanisms in aging and current strategies to counteract sarcopenia. Curr Aging Sci. 2010; 3:90-101.
-
(2010)
Curr Aging Sci
, vol.3
, pp. 90-101
-
-
Sakuma, K.1
Yamaguchi, A.2
-
24
-
-
4344674127
-
Hormonal and lifestyle determinants of appendicular skeletal muscle mass in men: the MINOS study
-
Szulc P, Duboeuf F, Marchand F, Delmas PD. Hormonal and lifestyle determinants of appendicular skeletal muscle mass in men: the MINOS study. Am J Clin Nutr. 2004; 80:496-503.
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 496-503
-
-
Szulc, P.1
Duboeuf, F.2
Marchand, F.3
Delmas, P.D.4
-
25
-
-
16844382376
-
Role of protein and amino acids in the pathophysiology and treatment of sarcopenia
-
Dreyer HC, Volpi E. Role of protein and amino acids in the pathophysiology and treatment of sarcopenia. J Am Coll Nutr. 2005; 24:140S-145S.
-
(2005)
J Am Coll Nutr
, vol.24
-
-
Dreyer, H.C.1
Volpi, E.2
-
26
-
-
55149101319
-
Sarcopenic obesity: definition, cause and consequences
-
Stenholm S, Harris TB, Rantanen T, Visser M, Kritchevsky SB, Ferrucci L. Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care. 2008; 11:693-700.
-
(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 693-700
-
-
Stenholm, S.1
Harris, T.B.2
Rantanen, T.3
Visser, M.4
Kritchevsky, S.B.5
Ferrucci, L.6
-
27
-
-
79960408766
-
Association Between Insulin Resistance and Lean Mass Loss and Fat Mass Gain in Older Men without Diabetes Mellitus
-
Lee CG, Boyko EJ, Strotmeyer ES, Lewis CE, Cawthon PM, Hoffman AR, Everson-Rose SA, Barrett-Connor E, Orwoll ES. Association Between Insulin Resistance and Lean Mass Loss and Fat Mass Gain in Older Men without Diabetes Mellitus. J Am Geriatr Soc. 2011; 59:1217-1224.
-
(2011)
J Am Geriatr Soc
, vol.59
, pp. 1217-1224
-
-
Lee, C.G.1
Boyko, E.J.2
Strotmeyer, E.S.3
Lewis, C.E.4
Cawthon, P.M.5
Hoffman, A.R.6
Everson-Rose, S.A.7
Barrett-Connor, E.8
Orwoll, E.S.9
-
28
-
-
79959539851
-
Normalizing a hyperactive mTOR initiates muscle growth during obesity
-
Williamson DL. Normalizing a hyperactive mTOR initiates muscle growth during obesity. Aging (Albany NY). 2011; 3:83-84.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 83-84
-
-
Williamson, D.L.1
-
29
-
-
78649823068
-
Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle
-
McKiernan SH, Colman RJ, Lopez M, Beasley TM, Aiken JM, Anderson RM, Weindruch R. Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle. Exp Gerontol. 2011; 46:23-29.
-
(2011)
Exp Gerontol
, vol.46
, pp. 23-29
-
-
McKiernan, S.H.1
Colman, R.J.2
Lopez, M.3
Beasley, T.M.4
Aiken, J.M.5
Anderson, R.M.6
Weindruch, R.7
-
30
-
-
39449100832
-
Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation
-
Leger B, Derave W, De Bock K, Hespel P, Russell AP. Human sarcopenia reveals an increase in SOCS-3 and myostatin and a reduced efficiency of Akt phosphorylation. Rejuvenation Res. 2008; 11:163-175B.
-
(2008)
Rejuvenation Res
, vol.11
-
-
Leger, B.1
Derave, W.2
De Bock, K.3
Hespel, P.4
Russell, A.P.5
-
31
-
-
77953648439
-
Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1
-
Kondratov RV, Vykhovanets O, Kondratova AA, Antoch MP. Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1. Aging (Albany NY). 2009; 1:979-987.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 979-987
-
-
Kondratov, R.V.1
Vykhovanets, O.2
Kondratova, A.A.3
Antoch, M.P.4
-
32
-
-
0036136997
-
Aging of the human neuromuscular system
-
Vandervoort AA. Aging of the human neuromuscular system. Muscle Nerve. 2002; 25:17-25.
-
(2002)
Muscle Nerve
, vol.25
, pp. 17-25
-
-
Vandervoort, A.A.1
-
33
-
-
75649152800
-
Role of the nervous system in sarcopenia and muscle atrophy with aging: strength training as a countermeasure
-
Aagaard P, Suetta C, Caserotti P, Magnusson SP, Kjaer M. Role of the nervous system in sarcopenia and muscle atrophy with aging: strength training as a countermeasure. Scand J Med Sci Sports. 2010; 20:49-64.
-
(2010)
Scand J Med Sci Sports
, vol.20
, pp. 49-64
-
-
Aagaard, P.1
Suetta, C.2
Caserotti, P.3
Magnusson, S.P.4
Kjaer, M.5
-
34
-
-
79952202632
-
Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis
-
Romero-Suarez S, Shen J, Brotto L, Hall T, Mo C, Valdivia HH, Andresen J, Wacker M, Nosek TM, Qu CK, Brotto M. Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis. Aging (Albany NY). 2010; 2:504-513.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 504-513
-
-
Romero-Suarez, S.1
Shen, J.2
Brotto, L.3
Hall, T.4
Mo, C.5
Valdivia, H.H.6
Andresen, J.7
Wacker, M.8
Nosek, T.M.9
Qu, C.K.10
Brotto, M.11
-
35
-
-
77952557041
-
The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis
-
Perrini S, Laviola L, Carreira MC, Cignarelli A, Natalicchio A, Giorgino F. The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis. J Endocrinol. 2010; 205:201-210.
-
(2010)
J Endocrinol
, vol.205
, pp. 201-210
-
-
Perrini, S.1
Laviola, L.2
Carreira, M.C.3
Cignarelli, A.4
Natalicchio, A.5
Giorgino, F.6
-
36
-
-
77953078946
-
Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1
-
Scicchitano BM, Rizzuto E, Musaro A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY). 2009; 1:451-457.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 451-457
-
-
Scicchitano, B.M.1
Rizzuto, E.2
Musaro, A.3
-
37
-
-
0030849677
-
The association of plasma IL-6 levels with functional disability in community-dwelling elderly
-
Cohen HJ, Pieper CF, Harris T, Rao KM, Currie MS. The association of plasma IL-6 levels with functional disability in community-dwelling elderly. J Gerontol A Biol Sci Med Sci. 1997; 52:M201-208.
-
(1997)
J Gerontol A Biol Sci Med Sci
, vol.52
-
-
Cohen, H.J.1
Pieper, C.F.2
Harris, T.3
Rao, K.M.4
Currie, M.S.5
-
38
-
-
0033024330
-
Serum IL-6 level and the development of disability in older persons
-
Ferrucci L, Harris TB, Guralnik JM, Tracy RP, Corti MC, Cohen HJ, Penninx B, Pahor M, Wallace R, Havlik RJ. Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc. 1999; 47:639-646.
-
(1999)
J Am Geriatr Soc
, vol.47
, pp. 639-646
-
-
Ferrucci, L.1
Harris, T.B.2
Guralnik, J.M.3
Tracy, R.P.4
Corti, M.C.5
Cohen, H.J.6
Penninx, B.7
Pahor, M.8
Wallace, R.9
Havlik, R.J.10
-
39
-
-
0036237810
-
Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study
-
Visser M, Pahor M, Taaffe DR, Goodpaster BH, Simonsick EM, Newman AB, Nevitt M, Harris TB. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2002; 57:M326-332.
-
(2002)
J Gerontol A Biol Sci Med Sci
, vol.57
-
-
Visser, M.1
Pahor, M.2
Taaffe, D.R.3
Goodpaster, B.H.4
Simonsick, E.M.5
Newman, A.B.6
Nevitt, M.7
Harris, T.B.8
-
40
-
-
78349286802
-
MAP kinase phosphatase-1-a new player at the nexus between sarcopenia and metabolic disease
-
Flach RJ, Bennett AM. MAP kinase phosphatase-1-a new player at the nexus between sarcopenia and metabolic disease. Aging (Albany NY). 2010; 2:170-176.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 170-176
-
-
Flach, R.J.1
Bennett, A.M.2
-
41
-
-
33846111415
-
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans
-
Franceschi C, Capri M, Monti D, Giunta S, Olivieri F, Sevini F, Panourgia MP, Invidia L, Celani L, Scurti M, Cevenini E, Castellani GC, Salvioli S. Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev. 2007; 128:92-105.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 92-105
-
-
Franceschi, C.1
Capri, M.2
Monti, D.3
Giunta, S.4
Olivieri, F.5
Sevini, F.6
Panourgia, M.P.7
Invidia, L.8
Celani, L.9
Scurti, M.10
Cevenini, E.11
Castellani, G.C.12
Salvioli, S.13
-
42
-
-
40949123149
-
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
-
Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev. 2008; 7:83-105.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 83-105
-
-
Salminen, A.1
Huuskonen, J.2
Ojala, J.3
Kauppinen, A.4
Kaarniranta, K.5
Suuronen, T.6
-
43
-
-
70350437283
-
Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength
-
Schaap LA, Pluijm SM, Deeg DJ, Harris TB, Kritchevsky SB, Newman AB, Colbert LH, Pahor M, Rubin SM, Tylavsky FA, Visser M. Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci. 2009; 64:1183-1189.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 1183-1189
-
-
Schaap, L.A.1
Pluijm, S.M.2
Deeg, D.J.3
Harris, T.B.4
Kritchevsky, S.B.5
Newman, A.B.6
Colbert, L.H.7
Pahor, M.8
Rubin, S.M.9
Tylavsky, F.A.10
Visser, M.11
-
44
-
-
77749293085
-
Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging
-
Marzetti E, Privitera G, Simili V, Wohlgemuth SE, Aulisa L, Pahor M, Leeuwenburgh C. Multiple pathways to the same end: mechanisms of myonuclear apoptosis in sarcopenia of aging. ScientificWorldJournal. 2010; 10:340-349.
-
(2010)
ScientificWorldJournal
, vol.10
, pp. 340-349
-
-
Marzetti, E.1
Privitera, G.2
Simili, V.3
Wohlgemuth, S.E.4
Aulisa, L.5
Pahor, M.6
Leeuwenburgh, C.7
-
45
-
-
32144457727
-
Intracellular signaling during skeletal muscle atrophy
-
Kandarian SC, Jackman RW. Intracellular signaling during skeletal muscle atrophy. Muscle Nerve. 2006; 33:155-165.
-
(2006)
Muscle Nerve
, vol.33
, pp. 155-165
-
-
Kandarian, S.C.1
Jackman, R.W.2
-
46
-
-
32244436294
-
The role of NF-kappaB in protein breakdown in immobilization, aging, and exercise: from basic processes to promotion of health
-
Bar-Shai M, Carmeli E, Reznick AZ. The role of NF-kappaB in protein breakdown in immobilization, aging, and exercise: from basic processes to promotion of health. Ann N Y Acad Sci. 2005; 1057:431-447.
-
(2005)
Ann N Y Acad Sci
, vol.1057
, pp. 431-447
-
-
Bar-Shai, M.1
Carmeli, E.2
Reznick, A.Z.3
-
47
-
-
2942662046
-
NF-kappaB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight
-
Agusti A, Morla M, Sauleda J, Saus C, Busquets X. NF-kappaB activation and iNOS upregulation in skeletal muscle of patients with COPD and low body weight. Thorax. 2004; 59:483-487.
-
(2004)
Thorax
, vol.59
, pp. 483-487
-
-
Agusti, A.1
Morla, M.2
Sauleda, J.3
Saus, C.4
Busquets, X.5
-
48
-
-
67649982995
-
Mechanisms of cancer cachexia
-
Tisdale MJ. Mechanisms of cancer cachexia. Physiol Rev. 2009; 89:381-410.
-
(2009)
Physiol Rev
, vol.89
, pp. 381-410
-
-
Tisdale, M.J.1
-
49
-
-
79954552450
-
Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies
-
Dodson S, Baracos VE, Jatoi A, Evans WJ, Cella D, Dalton JT, Steiner MS. Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies. Annu Rev Med. 2010.
-
(2010)
Annu Rev Med
-
-
Dodson, S.1
Baracos, V.E.2
Jatoi, A.3
Evans, W.J.4
Cella, D.5
Dalton, J.T.6
Steiner, M.S.7
-
52
-
-
0000654568
-
The immediate causes of death in cancer
-
Warren S. The immediate causes of death in cancer. Am J Med Sci. 1932; 184:610-615.
-
(1932)
Am J Med Sci
, vol.184
, pp. 610-615
-
-
Warren, S.1
-
53
-
-
0023731371
-
Risk factors for postoperative pneumonia. The importance of protein depletion
-
Windsor JA, Hill GL. Risk factors for postoperative pneumonia. The importance of protein depletion. Ann Surg. 1988; 208:209-214.
-
(1988)
Ann Surg
, vol.208
, pp. 209-214
-
-
Windsor, J.A.1
Hill, G.L.2
-
54
-
-
0035328839
-
Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid
-
Whitehouse AS, Smith HJ, Drake JL, Tisdale MJ. Mechanism of attenuation of skeletal muscle protein catabolism in cancer cachexia by eicosapentaenoic acid. Cancer Res. 2001; 61:3604-3609.
-
(2001)
Cancer Res
, vol.61
, pp. 3604-3609
-
-
Whitehouse, A.S.1
Smith, H.J.2
Drake, J.L.3
Tisdale, M.J.4
-
55
-
-
0030688961
-
ABC of palliative care. Anorexia, cachexia, and nutrition
-
Bruera E. ABC of palliative care. Anorexia, cachexia, and nutrition. BMJ. 1997; 315:1219-1222.
-
(1997)
BMJ
, vol.315
, pp. 1219-1222
-
-
Bruera, E.1
-
56
-
-
55749085001
-
Cachexia: a new definition
-
Evans WJ, Morley JE, Argiles J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, Rossi Fanelli F et al. Cachexia: a new definition. Clin Nutr. 2008; 27:793-799.
-
(2008)
Clin Nutr
, vol.27
, pp. 793-799
-
-
Evans, W.J.1
Morley, J.E.2
Argiles, J.3
Bales, C.4
Baracos, V.5
Guttridge, D.6
Jatoi, A.7
Kalantar-Zadeh, K.8
Lochs, H.9
Mantovani, G.10
Marks, D.11
Mitch, W.E.12
Muscaritoli, M.13
Najand, A.14
Ponikowski, P.15
Rossi Fanelli, F.16
-
58
-
-
0035259388
-
Loss of skeletal muscle in cancer: biochemical mechanisms
-
Tisdale MJ. Loss of skeletal muscle in cancer: biochemical mechanisms. Front Biosci. 2001; 6:D164-174.
-
(2001)
Front Biosci
, vol.6
-
-
Tisdale, M.J.1
-
59
-
-
12344305118
-
Steep elevation of blood interleukin-6 (IL-6) associated only with late stages of cachexia in cancer patients
-
Iwase S, Murakami T, Saito Y, Nakagawa K. Steep elevation of blood interleukin-6 (IL-6) associated only with late stages of cachexia in cancer patients. Eur Cytokine Netw. 2004; 15:312-316.
-
(2004)
Eur Cytokine Netw
, vol.15
, pp. 312-316
-
-
Iwase, S.1
Murakami, T.2
Saito, Y.3
Nakagawa, K.4
-
60
-
-
28044448490
-
Myofiber degeneration/regeneration is induced in the cachectic ApcMin/+ mouse
-
Mehl KA, Davis JM, Berger FG, Carson JA. Myofiber degeneration/regeneration is induced in the cachectic ApcMin/+ mouse. J Appl Physiol. 2005; 99:2379-2387.
-
(2005)
J Appl Physiol
, vol.99
, pp. 2379-2387
-
-
Mehl, K.A.1
Davis, J.M.2
Berger, F.G.3
Carson, J.A.4
-
61
-
-
38949137388
-
Interleukin-6 and cachexia in ApcMin/+ mice
-
Baltgalvis KA, Berger FG, Pena MM, Davis JM, Muga SJ, Carson JA. Interleukin-6 and cachexia in ApcMin/+ mice. Am J Physiol Regul Integr Comp Physiol. 2008; 294:R393-401.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Baltgalvis, K.A.1
Berger, F.G.2
Pena, M.M.3
Davis, J.M.4
Muga, S.J.5
Carson, J.A.6
-
62
-
-
13344261948
-
Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice
-
Tsujinaka T, Fujita J, Ebisui C, Yano M, Kominami E, Suzuki K, Tanaka K, Katsume A, Ohsugi Y, Shiozaki H, Monden M. Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice. J Clin Invest. 1996; 97:244-249.
-
(1996)
J Clin Invest
, vol.97
, pp. 244-249
-
-
Tsujinaka, T.1
Fujita, J.2
Ebisui, C.3
Yano, M.4
Kominami, E.5
Suzuki, K.6
Tanaka, K.7
Katsume, A.8
Ohsugi, Y.9
Shiozaki, H.10
Monden, M.11
-
63
-
-
0028789750
-
Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes
-
Ebisui C, Tsujinaka T, Morimoto T, Kan K, Iijima S, Yano M, Kominami E, Tanaka K, Monden M. Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes. Clin Sci (Lond). 1995; 89:431-439.
-
(1995)
Clin Sci (Lond)
, vol.89
, pp. 431-439
-
-
Ebisui, C.1
Tsujinaka, T.2
Morimoto, T.3
Kan, K.4
Iijima, S.5
Yano, M.6
Kominami, E.7
Tanaka, K.8
Monden, M.9
-
64
-
-
0027196193
-
Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor
-
Strassmann G, Masui Y, Chizzonite R, Fong M. Mechanisms of experimental cancer cachexia. Local involvement of IL-1 in colon-26 tumor. J Immunol. 1993; 150:2341-2345.
-
(1993)
J Immunol
, vol.150
, pp. 2341-2345
-
-
Strassmann, G.1
Masui, Y.2
Chizzonite, R.3
Fong, M.4
-
65
-
-
0026532492
-
Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia
-
Strassmann G, Jacob CO, Evans R, Beall D, Fong M. Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia. J Immunol. 1992; 148:3674-3678.
-
(1992)
J Immunol
, vol.148
, pp. 3674-3678
-
-
Strassmann, G.1
Jacob, C.O.2
Evans, R.3
Beall, D.4
Fong, M.5
-
66
-
-
0000498853
-
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins
-
Fong Y, Moldawer LL, Marano M, Wei H, Barber A, Manogue K, Tracey KJ, Kuo G, Fischman DA, Cerami A, et al. Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins. Am J Physiol. 1989; 256:R659-665.
-
(1989)
Am J Physiol
, vol.256
-
-
Fong, Y.1
Moldawer, L.L.2
Marano, M.3
Wei, H.4
Barber, A.5
Manogue, K.6
Tracey, K.J.7
Kuo, G.8
Fischman, D.A.9
Cerami, A.10
-
67
-
-
0028114904
-
Interleukin-1 receptor antagonist prevents sepsis-induced inhibition of protein synthesis
-
Cooney R, Owens E, Jurasinski C, Gray K, Vannice J, Vary T. Interleukin-1 receptor antagonist prevents sepsis-induced inhibition of protein synthesis. Am J Physiol. 1994; 267:E636-641.
-
(1994)
Am J Physiol
, vol.267
-
-
Cooney, R.1
Owens, E.2
Jurasinski, C.3
Gray, K.4
Vannice, J.5
Vary, T.6
-
68
-
-
0023638415
-
Tumors secreting human TNF/cachectin induce cachexia in mice
-
Oliff A, Defeo-Jones D, Boyer M, Martinez D, Kiefer D, Vuocolo G, Wolfe A, Socher SH. Tumors secreting human TNF/cachectin induce cachexia in mice. Cell. 1987; 50:555-563.
-
(1987)
Cell
, vol.50
, pp. 555-563
-
-
Oliff, A.1
Defeo-Jones, D.2
Boyer, M.3
Martinez, D.4
Kiefer, D.5
Vuocolo, G.6
Wolfe, A.7
Socher, S.H.8
-
69
-
-
0032516677
-
Protein turnover in skeletal muscle of tumour-bearing transgenic mice overexpressing the soluble TNF receptor-1
-
Llovera M, García-Martínez C, López-Soriano J, Agell N, López-Soriano FJ, Garcia I, Argilés JM. Protein turnover in skeletal muscle of tumour-bearing transgenic mice overexpressing the soluble TNF receptor-1. Cancer Letters. 1998; 130:19-27.
-
(1998)
Cancer Letters
, vol.130
, pp. 19-27
-
-
Llovera, M.1
García-Martínez, C.2
López-Soriano, J.3
Agell, N.4
López-Soriano, F.J.5
Garcia, I.6
Argilés, J.M.7
-
70
-
-
0036234459
-
Missing pieces in the NF-kappaB puzzle
-
Ghosh S, Karin M. Missing pieces in the NF-kappaB puzzle. Cell. 2002; 109 Suppl:S81-96.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Ghosh, S.1
Karin, M.2
-
71
-
-
0033696398
-
NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes
-
Li YP, Reid MB. NF-kappaB mediates the protein loss induced by TNF-alpha in differentiated skeletal muscle myotubes. Am J Physiol Regul Integr Comp Physiol. 2000; 279:R1165-1170.
-
(2000)
Am J Physiol Regul Integr Comp Physiol
, vol.279
-
-
Li, Y.P.1
Reid, M.B.2
-
72
-
-
0028028069
-
Cytokine-induced expression of nitric oxide synthase in C2C12 skeletal muscle myocytes
-
Williams G, Brown T, Becker L, Prager M, Giroir BP. Cytokine-induced expression of nitric oxide synthase in C2C12 skeletal muscle myocytes. Am J Physiol. 1994; 267:R1020-1025.
-
(1994)
Am J Physiol
, vol.267
-
-
Williams, G.1
Brown, T.2
Becker, L.3
Prager, M.4
Giroir, B.P.5
-
73
-
-
0034730251
-
NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia
-
Guttridge DC, Mayo MW, Madrid LV, Wang CY, Baldwin AS, Jr. NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. Science. 2000; 289:2363-2366.
-
(2000)
Science
, vol.289
, pp. 2363-2366
-
-
Guttridge, D.C.1
Mayo, M.W.2
Madrid, L.V.3
Wang, C.Y.4
Baldwin Jr., A.S.5
-
74
-
-
0025887050
-
Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells
-
Matthys P, Dijkmans R, Proost P, Van Damme J, Heremans H, Sobis H, Billiau A. Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells. Int J Cancer. 1991; 49:77-82.
-
(1991)
Int J Cancer
, vol.49
, pp. 77-82
-
-
Matthys, P.1
Dijkmans, R.2
Proost, P.3
Van Damme, J.4
Heremans, H.5
Sobis, H.6
Billiau, A.7
-
75
-
-
0031802331
-
Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha
-
Li YP, Schwartz RJ, Waddell ID, Holloway BR, Reid MB. Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha. FASEB J. 1998; 12:871-880.
-
(1998)
FASEB J
, vol.12
, pp. 871-880
-
-
Li, Y.P.1
Schwartz, R.J.2
Waddell, I.D.3
Holloway, B.R.4
Reid, M.B.5
-
76
-
-
0011986806
-
Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies
-
D'Acquisto F, May MJ, Ghosh S. Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies. Mol Interv. 2002; 2:22-35.
-
(2002)
Mol Interv
, vol.2
, pp. 22-35
-
-
D'Acquisto, F.1
May, M.J.2
Ghosh, S.3
-
77
-
-
0035139792
-
Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
-
Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest. 2001; 107:135-142.
-
(2001)
J Clin Invest
, vol.107
, pp. 135-142
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
78
-
-
79751492851
-
NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma
-
Luedde T, Schwabe RF. NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2011; 8:108-118.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 108-118
-
-
Luedde, T.1
Schwabe, R.F.2
-
79
-
-
17144449583
-
High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation
-
Lavon I, Goldberg I, Amit S, Landsman L, Jung S, Tsuberi BZ, Barshack I, Kopolovic J, Galun E, Bujard H, Ben-Neriah Y. High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation. Nat Med. 2000; 6:573-577.
-
(2000)
Nat Med
, vol.6
, pp. 573-577
-
-
Lavon, I.1
Goldberg, I.2
Amit, S.3
Landsman, L.4
Jung, S.5
Tsuberi, B.Z.6
Barshack, I.7
Kopolovic, J.8
Galun, E.9
Bujard, H.10
Ben-Neriah, Y.11
-
80
-
-
0037127223
-
Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-kappa B DNA binding activity
-
Matata BM, Galinanes M. Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-kappa B DNA binding activity. J Biol Chem. 2002; 277:2330-2335.
-
(2002)
J Biol Chem
, vol.277
, pp. 2330-2335
-
-
Matata, B.M.1
Galinanes, M.2
-
81
-
-
70349664576
-
Endotoxin and interferon-gamma inhibit translation in skeletal muscle cells by stimulating nitric oxide synthase activity
-
Frost RA, Nystrom GJ, Lang CH. Endotoxin and interferon-gamma inhibit translation in skeletal muscle cells by stimulating nitric oxide synthase activity. Shock. 2009; 32:416-426.
-
(2009)
Shock
, vol.32
, pp. 416-426
-
-
Frost, R.A.1
Nystrom, G.J.2
Lang, C.H.3
-
82
-
-
21244457292
-
Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry
-
Kanski J, Hong SJ, Schoneich C. Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass spectrometry. J Biol Chem. 2005; 280:24261-24266.
-
(2005)
J Biol Chem
, vol.280
, pp. 24261-24266
-
-
Kanski, J.1
Hong, S.J.2
Schoneich, C.3
-
83
-
-
0030061132
-
Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process?
-
Viner RI, Ferrington DA, Huhmer AF, Bigelow DJ, Schoneich C. Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process? FEBS Lett. 1996; 379:286-290.
-
(1996)
FEBS Lett
, vol.379
, pp. 286-290
-
-
Viner, R.I.1
Ferrington, D.A.2
Huhmer, A.F.3
Bigelow, D.J.4
Schoneich, C.5
-
84
-
-
77950815689
-
Nitration of specific tyrosines in FoF1 ATP synthase and activity loss in aging
-
Haynes V, Traaseth NJ, Elfering S, Fujisawa Y, Giulivi C. Nitration of specific tyrosines in FoF1 ATP synthase and activity loss in aging. Am J Physiol Endocrinol Metab. 2010; 298:E978-987.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Haynes, V.1
Traaseth, N.J.2
Elfering, S.3
Fujisawa, Y.4
Giulivi, C.5
-
85
-
-
0036570159
-
Oxidatively modified proteins in aging and disease
-
Beal MF. Oxidatively modified proteins in aging and disease. Free Radic Biol Med. 2002; 32:797-803.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 797-803
-
-
Beal, M.F.1
-
86
-
-
0026585611
-
Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis
-
Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J. 1992; 281 (Pt 1):21-40.
-
(1992)
Biochem J
, vol.281
, Issue.PART 1
, pp. 21-40
-
-
Wallimann, T.1
Wyss, M.2
Brdiczka, D.3
Nicolay, K.4
Eppenberger, H.M.5
-
87
-
-
77953945008
-
Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle
-
Nuss JE, Amaning JK, Bailey CE, DeFord JH, Dimayuga VL, Rabek JP, Papaconstantinou J. Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle. Aging (Albany NY). 2009; 1:557-572.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 557-572
-
-
Nuss, J.E.1
Amaning, J.K.2
Bailey, C.E.3
DeFord, J.H.4
Dimayuga, V.L.5
Rabek, J.P.6
Papaconstantinou, J.7
-
88
-
-
0029954208
-
MyoD is required for myogenic stem cell function in adult skeletal muscle
-
Megeney LA, Kablar B, Garrett K, Anderson JE, Rudnicki MA. MyoD is required for myogenic stem cell function in adult skeletal muscle. Genes Dev. 1996; 10:1173-1183.
-
(1996)
Genes Dev
, vol.10
, pp. 1173-1183
-
-
Megeney, L.A.1
Kablar, B.2
Garrett, K.3
Anderson, J.E.4
Rudnicki, M.A.5
-
89
-
-
0442324933
-
Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization
-
Langen RC, Van Der Velden JL, Schols AM, Kelders MC, Wouters EF, Janssen-Heininger YM. Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization. FASEB J. 2004; 18:227-237.
-
(2004)
FASEB J
, vol.18
, pp. 227-237
-
-
Langen, R.C.1
Van Der Velden, J.L.2
Schols, A.M.3
Kelders, M.C.4
Wouters, E.F.5
Janssen-Heininger, Y.M.6
-
90
-
-
4043154377
-
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
-
Acharyya S, Ladner KJ, Nelsen LL, Damrauer J, Reiser PJ, Swoap S, Guttridge DC. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J Clin Invest. 2004; 114:370-378.
-
(2004)
J Clin Invest
, vol.114
, pp. 370-378
-
-
Acharyya, S.1
Ladner, K.J.2
Nelsen, L.L.3
Damrauer, J.4
Reiser, P.J.5
Swoap, S.6
Guttridge, D.C.7
-
91
-
-
0037102398
-
Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments
-
Reid MB, Lannergren J, Westerblad H. Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments. Am J Respir Crit Care Med. 2002; 166:479-484.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 479-484
-
-
Reid, M.B.1
Lannergren, J.2
Westerblad, H.3
-
92
-
-
41549114074
-
TNF-alpha acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle
-
Hardin BJ, Campbell KS, Smith JD, Arbogast S, Smith J, Moylan JS, Reid MB. TNF-alpha acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle. J Appl Physiol. 2008; 104:694-699.
-
(2008)
J Appl Physiol
, vol.104
, pp. 694-699
-
-
Hardin, B.J.1
Campbell, K.S.2
Smith, J.D.3
Arbogast, S.4
Smith, J.5
Moylan, J.S.6
Reid, M.B.7
-
93
-
-
0030061515
-
Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter
-
de Vera ME, Shapiro RA, Nussler AK, Mudgett JS, Simmons RL, Morris SM, Jr., Billiar TR, Geller DA. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci U S A. 1996; 93:1054-1059.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1054-1059
-
-
de Vera, M.E.1
Shapiro, R.A.2
Nussler, A.K.3
Mudgett, J.S.4
Simmons, R.L.5
Morris Jr., S.M.6
Billiar, T.R.7
Geller, D.A.8
-
94
-
-
0030860442
-
Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line
-
Linn SC, Morelli PJ, Edry I, Cottongim SE, Szabo C, Salzman AL. Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line. Am J Physiol. 1997; 272:G1499-1508.
-
(1997)
Am J Physiol
, vol.272
-
-
Linn, S.C.1
Morelli, P.J.2
Edry, I.3
Cottongim, S.E.4
Szabo, C.5
Salzman, A.L.6
-
95
-
-
0034714259
-
Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR
-
Rodriguez-Pascual F, Hausding M, Ihrig-Biedert I, Furneaux H, Levy AP, Forstermann U, Kleinert H. Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR. J Biol Chem. 2000; 275:26040-26049.
-
(2000)
J Biol Chem
, vol.275
, pp. 26040-26049
-
-
Rodriguez-Pascual, F.1
Hausding, M.2
Ihrig-Biedert, I.3
Furneaux, H.4
Levy, A.P.5
Forstermann, U.6
Kleinert, H.7
-
96
-
-
0023058975
-
A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
-
Shaw G, Kamen R. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell. 1986; 46:659-667.
-
(1986)
Cell
, vol.46
, pp. 659-667
-
-
Shaw, G.1
Kamen, R.2
-
97
-
-
0041523923
-
Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes
-
Yang E, van Nimwegen E, Zavolan M, Rajewsky N, Schroeder M, Magnasco M, Darnell JE, Jr. Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res. 2003; 13:1863-1872.
-
(2003)
Genome Res
, vol.13
, pp. 1863-1872
-
-
Yang, E.1
van Nimwegen, E.2
Zavolan, M.3
Rajewsky, N.4
Schroeder, M.5
Magnasco, M.6
Darnell Jr., J.E.7
-
98
-
-
0029973094
-
Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
-
Jacobson A, Peltz SW. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu Rev Biochem. 1996; 65:693-739.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 693-739
-
-
Jacobson, A.1
Peltz, S.W.2
-
99
-
-
0034850959
-
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock
-
Gallouzi IE, Brennan CM, Steitz JA. Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. RNA. 2001; 7:1348-1361.
-
(2001)
RNA
, vol.7
, pp. 1348-1361
-
-
Gallouzi, I.E.1
Brennan, C.M.2
Steitz, J.A.3
-
100
-
-
0034597057
-
Protein ligands to HuR modulate its interaction with target mRNAs in vivo
-
Brennan CM, Gallouzi IE, Steitz JA. Protein ligands to HuR modulate its interaction with target mRNAs in vivo. J Cell Biol. 2000; 151:1-14.
-
(2000)
J Cell Biol
, vol.151
, pp. 1-14
-
-
Brennan, C.M.1
Gallouzi, I.E.2
Steitz, J.A.3
-
101
-
-
0032526427
-
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
-
Fan XC, Steitz JA. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 1998; 17:3448-3460.
-
(1998)
EMBO J
, vol.17
, pp. 3448-3460
-
-
Fan, X.C.1
Steitz, J.A.2
-
102
-
-
0032526417
-
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
-
Peng SS, Chen CY, Xu N, Shyu AB. RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J. 1998; 17:3461-3470.
-
(1998)
EMBO J
, vol.17
, pp. 3461-3470
-
-
Peng, S.S.1
Chen, C.Y.2
Xu, N.3
Shyu, A.B.4
-
103
-
-
0035976612
-
Delineation of mRNA export pathways by the use of cell-permeable peptides
-
Gallouzi IE, Steitz JA. Delineation of mRNA export pathways by the use of cell-permeable peptides. Science. 2001; 294:1895-1901.
-
(2001)
Science
, vol.294
, pp. 1895-1901
-
-
Gallouzi, I.E.1
Steitz, J.A.2
-
104
-
-
0031902602
-
Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: nitric oxide induces phosphorylation of initiation factor eIF-2 alpha
-
Kim YM, Son K, Hong SJ, Green A, Chen JJ, Tzeng E, Hierholzer C, Billiar TR. Inhibition of protein synthesis by nitric oxide correlates with cytostatic activity: nitric oxide induces phosphorylation of initiation factor eIF-2 alpha. Mol Med. 1998; 4:179-190.
-
(1998)
Mol Med
, vol.4
, pp. 179-190
-
-
Kim, Y.M.1
Son, K.2
Hong, S.J.3
Green, A.4
Chen, J.J.5
Tzeng, E.6
Hierholzer, C.7
Billiar, T.R.8
-
105
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
-
Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol. 1996; 271:C1424-1437.
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
106
-
-
78650152988
-
p53, ROS and senescence in the control of aging
-
Vigneron A, Vousden KH. p53, ROS and senescence in the control of aging. Aging (Albany NY). 2010; 2:471-474.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 471-474
-
-
Vigneron, A.1
Vousden, K.H.2
-
107
-
-
79952109629
-
P66SHC and ageing: ROS and TOR?
-
Pani G. P66SHC and ageing: ROS and TOR? Aging (Albany NY). 2010; 2:514-518.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 514-518
-
-
Pani, G.1
-
108
-
-
55849152355
-
Aging: ROS or TOR
-
Blagosklonny MV. Aging: ROS or TOR. Cell Cycle. 2008; 7:3344-3354.
-
(2008)
Cell Cycle
, vol.7
, pp. 3344-3354
-
-
Blagosklonny, M.V.1
-
109
-
-
77957653679
-
Mitochondrial redox potential during contraction in single intact muscle fibers
-
Michaelson LP, Shi G, Ward CW, Rodney GG. Mitochondrial redox potential during contraction in single intact muscle fibers. Muscle Nerve. 2010; 42:522-529.
-
(2010)
Muscle Nerve
, vol.42
, pp. 522-529
-
-
Michaelson, L.P.1
Shi, G.2
Ward, C.W.3
Rodney, G.G.4
-
112
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan C. Nitric oxide and the immune response. Nat Immunol. 2001; 2:907-916.
-
(2001)
Nat Immunol
, vol.2
, pp. 907-916
-
-
Bogdan, C.1
|