-
1
-
-
55149101319
-
Sarcopenic obesity: definition, cause and consequences
-
Stenholm S, Harris TB, Rantanen T, Visser M, Kritchevsky SB, et al. Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care. 2008; 11:693-700.
-
(2008)
Curr Opin Clin Nutr Metab Care.
, vol.11
, pp. 693-700
-
-
Stenholm, S.1
Harris, T.B.2
Rantanen, T.3
Visser, M.4
Kritchevsky, S.B.5
-
2
-
-
0021066904
-
Skeletal muscle growth in lean and obese Zucker rats
-
Durschlag RP, Layman DK. Skeletal muscle growth in lean and obese Zucker rats. Growth 1983. 47:282-291.
-
(1983)
Growth
, vol.47
, pp. 282-291
-
-
Durschlag, R.P.1
Layman, D.K.2
-
3
-
-
68949151833
-
Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse
-
Kemp JG, Blazev R, Stephenson DG, Stephenson GM. Morphological and biochemical alterations of skeletal muscles from the genetically obese (ob/ob) mouse. Int J Obes (Lond). 2009; 33:831-841.
-
(2009)
Int J Obes (Lond).
, vol.33
, pp. 831-841
-
-
Kemp, J.G.1
Blazev, R.2
Stephenson, D.G.3
Stephenson, G.M.4
-
4
-
-
0030066934
-
Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
-
Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 1996; 15:658-664.
-
(1996)
EMBO J.
, vol.15
, pp. 658-664
-
-
Beretta, L.1
Gingras, A.C.2
Svitkin, Y.V.3
Hall, M.N.4
Sonenberg, N.5
-
5
-
-
0002523042
-
The pathway and mechanism of eukaryotic protein synthesis
-
Hershey JWB, Mathews MB, Sonenberg N, editors. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Merrick WC, Hershey JWB. The pathway and mechanism of eukaryotic protein synthesis. In: Hershey JWB, Mathews MB, Sonenberg N, editors. Translational Control. Cold Spring Harbor: Cold Spring Harbor Laboratory Press. 1996; 31-69.
-
(1996)
Translational Control
, vol.31
, pp. 69
-
-
Merrick, W.C.1
Hershey, J.W.B.2
-
6
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz MK, Ballif BA, Gygi SP, Blenis J. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell. 2005; 123:569-580.
-
(2005)
Cell.
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
7
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature. 2004; 431:200-205.
-
(2004)
Nature.
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
-
8
-
-
57349116906
-
Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice
-
Miller AM, Brestoff JR, Phelps CB, Berk EZ, Reynolds TH. Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice. Am J Physiol Regul Integr Comp Physiol. 2008; 295:R1431-1438.
-
(2008)
Am J Physiol Regul Integr Comp Physiol.
, vol.295
-
-
Miller, A.M.1
Brestoff, J.R.2
Phelps, C.B.3
Berk, E.Z.4
Reynolds, T.H.5
-
9
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009; 460:392-395.
-
(2009)
Nature.
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
-
10
-
-
77952083662
-
Rapamycin extends maximal lifespan in cancer-prone mice
-
Anisimov VN, Zabezhinski MA, Popovich IG, Piskunova TS, Semenchenko AV, et al. Rapamycin extends maximal lifespan in cancer-prone mice. Am J Pathol. 2010; 176:2092-2097.
-
(2010)
Am J Pathol.
, vol.176
, pp. 2092-2097
-
-
Anisimov, V.N.1
Zabezhinski, M.A.2
Popovich, I.G.3
Piskunova, T.S.4
Semenchenko, A.V.5
-
11
-
-
0036788292
-
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fatfed rats
-
Iglesias MA, Ye JM, Frangioudakis G, Saha AK, Tomas E, et al. AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fatfed rats. Diabetes. 2002; 51:2886-2894.
-
(2002)
Diabetes.
, vol.51
, pp. 2886-2894
-
-
Iglesias, M.A.1
Ye, J.M.2
Frangioudakis, G.3
Saha, A.K.4
Tomas, E.5
-
12
-
-
0344081177
-
Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status
-
Hardie DG. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology. 2003. 144:5179-5183.
-
(2003)
Endocrinology.
, vol.144
, pp. 5179-5183
-
-
Hardie, D.G.1
-
13
-
-
0037025356
-
AMPactivated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
-
Bolster DR, Crozier SJ, Kimball SR, Jefferson LS. AMPactivated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J Biol Chem. 2002; 277:23977-23980.
-
(2002)
J Biol Chem.
, vol.277
, pp. 23977-23980
-
-
Bolster, D.R.1
Crozier, S.J.2
Kimball, S.R.3
Jefferson, L.S.4
-
14
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell. 2003; 115:577-590.
-
(2003)
Cell.
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
15
-
-
78649814492
-
AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle
-
Drake JC, Alway SE, Hollander JM, Williamson DL. AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2010; 299:R1546-1554.
-
(2010)
Am J Physiol Regul Integr Comp Physiol.
, vol.299
-
-
Drake, J.C.1
Alway, S.E.2
Hollander, J.M.3
Williamson, D.L.4
-
16
-
-
77957567397
-
Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle
-
Saha AK, Xu XJ, Lawson E, Deoliveira R, Brandon AE, et al. Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes. 2010; 59:2426-2434.
-
(2010)
Diabetes.
, vol.59
, pp. 2426-2434
-
-
Saha, A.K.1
Xu, X.J.2
Lawson, E.3
Deoliveira, R.4
Brandon, A.E.5
-
17
-
-
70449625402
-
Aerobic Exercise Training Improves Whole Muscle and Single Myofiber Size and Function in Older Women
-
Harber MP, Konopka AR, Douglass MD, Minchev K, Kamisky LA, et al. Aerobic Exercise Training Improves Whole Muscle and Single Myofiber Size and Function in Older Women. Am J Physiol Regul Integr Comp Physiol. 2010; 297:R1452-1459.
-
(2010)
Am J Physiol Regul Integr Comp Physiol.
, vol.297
-
-
Harber, M.P.1
Konopka, A.R.2
Douglass, M.D.3
Minchev, K.4
Kamisky, L.A.5
-
18
-
-
78650848337
-
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
-
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 2010; 468:1100-1104.
-
(2010)
Nature.
, vol.468
, pp. 1100-1104
-
-
Sengupta, S.1
Peterson, T.R.2
Laplante, M.3
Oh, S.4
Sabatini, D.M.5
-
19
-
-
77953645579
-
Rapamycin and quasi-programmed aging: Four years later
-
Blagosklonny MV. Rapamycin and quasi-programmed aging: Four years later. Cell Cycle. 2010; 9:1859-1862.
-
(2010)
Cell Cycle.
, vol.9
, pp. 1859-1862
-
-
Blagosklonny, M.V.1
-
20
-
-
70349669095
-
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
-
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science. 2009; 326:140-144.
-
(2009)
Science.
, vol.326
, pp. 140-144
-
-
Selman, C.1
Tullet, J.M.2
Wieser, D.3
Irvine, E.4
Lingard, S.J.5
|