Increased renal methylglyoxal formation with down-regulation of PGC-1α-FBPase pathway in cystathionine γ-Lyase knockout mice

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Untereiner, Ashley A ^a,b   Dhar, Arti ^a   Liu, Jianghai ^a   Wu, Lingyun ^a,b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b LAKEHEAD UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CYSTATHIONINE GAMMA LYASE; ESTROGEN RELATED RECEPTOR ALPHA; FRUCTOSE BISPHOSPHATASE; GLUCOSE; HYDROGEN SULFIDE; MESSENGER RNA; METHYLGLYOXAL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRIOSEPHOSPHATE ISOMERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1; PEROXISOME-PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA COACTIVATOR-1; PRIMER DNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; AORTA; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; KIDNEY PARENCHYMA; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; BLOOD GLUCOSE; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTATHIONINE GAMMA-LYASE; DNA PRIMERS; DOWN-REGULATION; FRUCTOSE-BISPHOSPHATASE; KIDNEY; MALE; MICE; MICE, KNOCKOUT; PYRUVALDEHYDE; RATS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 84055182558     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029592     Document Type: Article

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