Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells

Cardiovascular Research

Volumn 86, Issue 3, 2010, Pages 487-495

  Yang, Guangdong ^a   Wu, Lingyun ^b   Bryan, Sean ^a   Khaper, Neelam ^a   Mani, Sarathi ^a   Wang, Rui ^a  

^a LAKEHEAD UNIVERSITY   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Apoptosis; Cystathionine gamma lyase; Hydrogen sulfide; Hypertension; Smooth muscle cell

Indexed keywords

BETA1 INTEGRIN; BROXURIDINE; CALCITONIN RECEPTOR LIKE RECEPTOR; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYSTATHIONINE GAMMA LYASE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HYDROGEN SULFIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; AORTA; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MESENTERIC ARTERY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; VASCULAR TISSUE; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ANTIGENS, CD29; AORTA; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYSTATHIONINE GAMMA-LYASE; GENE EXPRESSION PROFILING; HYDROGEN SULFIDE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RECEPTORS, CALCITONIN; RNA, MESSENGER; TIME FACTORS;

EID: 77952390040     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp420     Document Type: Article

References (39)

1. Feihl F, Liaudet L, Levy BI, Waeber B. Hypertension and microvascular remodeling. Cardiovasc Res 2008;78:274-285.
2. Lee RM, Owens GK, Scott-Burden T, Head RJ, Mulvany MJ, Schiffrin EL. Pathophysiol-ogy of smooth muscle in hypertension. Can J Physiol Pharmacol 1995;73:574-584.
3. Intengan HD, Schiffrin EL. Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis. Hypertension 2001;38:581-587.
4. Tanner FC, Greutert H, Barandier C, Frischknecht K, Luscher TF. Different cell cycle regulation of vascular smooth muscle in genetic hypertension. Hypertension 2003;42: 184-188.
5. Resink TJ, Scott-Burden T, Baur U, Buhler FR. Increased proliferation fate and phos-phoinositide turnover in cultured smooth muscle cells from spontaneously hypertensive rats. J Hypertens 1987;5:S145-S148.
6. Nakayama M, Fukuda N, Watanabe Y, Soma M, Hu WY, Kishioka H et al. Low dose of eicosapentaenoic acid inhibits the exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats through suppression of transforming growth factor-beta. J Hypertens 1999;17:1421-1430.
7. Kubo A, Fukuda N, Teng J, Satoh C, Nakayama M, Kishioka H et al. Angiotensin II regulates the cell cycle of vascular smooth muscle cells from SHR. Am J Hypertens 2000;13:1117-1124.
8. Hamet P, Richard L, Dam TV, Teiger E, Orlov SN, Gaboury L et al. Apoptosis in target organs of hypertension. Hypertension 1995;26:642-648.
9. Devlin AM, Clark JS, Reid JL, Dominiczak AF. DNA synthesis and apoptosis in smooth muscle cells from a model of genetic hypertension. Hypertension 2006;36:110-115.
10. 2S be the third endogenous gaseous transmitter? FASEB J 2002;16:1792-1798.
11. Wang R. The gasotransmitter role of hydrogen sulfide. Antioxid Redox Signal 2003;5: 493-501.
12. 2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 2008;322: 587-590.
13. ATP channel opener. EMBO J 2001;20:6008-6016.
14. Shi YX, Chen Y, Zhu YZ, Huang GY, Moore PK, Huang SH et al. Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2007;293:H2093-H2100.
15. Yang G, Sun X, Wang R. Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3. FASEB J 2004;18:1782-1784.
16. 2S on human aorta smooth muscle cells. FASEB J 2006;20:553-555.
17. Baskar R, Sparatore A, Del Soldato P, Moore PK. Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation. Eur J Pharmacol 2008;594:1-8.
18. 2S in rat tissues. Can J Physiol Pharmacol 2003;81:848-853.
19. Lu Y, Hanna ST, Tang G, Wang R. Contributions of Kv1.2, Kv1.5 and Kv2.1 subunits to the native delayed rectifier K(\+) current in rat mesenteric artery smooth muscle cells. Life Sci 2002;71:1465-1473.
20. Meng QH, Yang G, Yang W, Jiang B, Wu L, Wang R. Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries. Am J Pathol 2007;170:1406-1414.
21. Duka I, Shenouda S, Johns C, Kintsurashvili E, Gavras I, Gavras H. Role of the B(2) receptor of bradykinin in insulin sensitivity. Hypertension 2001;38:1355-1360.
22. Chang T, Wu L, Wang R. Altered expression of BK channel beta1 subunit in vascular tissues from spontaneously hypertensive rats. Am J Hypertens 2006;19:678-685.
23. Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004;84:767-801.
24. Metharom P, Caplice NM. Vascular disease: a new progenitor biology. Curr Vasc Pharmacol 2007;5:61-68.
25. Mariggio MA, Minunno V, Riccardi S, Santacroce R, De Rinaldis P, Fumarulo R. Sulfide enhancement of PMN apoptosis. Immunopharmacol Immunotoxicol 1998;20:399-408.
26. Rinaldi L, Gobbi G, Pambianco M, Micheloni C, Mirandola P, Vitale M. Hydrogen sulfide prevents apoptosis of human PMN via inhibition of p38 and caspase 3. Lab Invest 2006;86:391-1335
27. Cao Y, Adhikari S, Ang AD, Moore PK, Bhatia M. Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide. Am J Physiol Cell Physiol 2006;291: C503-C510. (Pubitemid 44343633)
28. 2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem 2007;282:16567-16576.
29. Baskar R, Li L, Moore PK. Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells. FASEB J 2007;21: 247-255.
30. Cip/WAF-1. J Biol Chem 2004;279:49199-49205.
31. Whiteman M, Moore PK. Hydrogen sulfide and the vasculature: a novel vasculopro-tective entity and regulator of nitric oxide bioavailability? J Cell Mol Med 2009;13: 488-507.
32. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270:1326-1331.
33. Schaeffer C, Vandroux D, Thomassin L, Athias P, Rochette L, Connat JL. Calcitonin gene-related peptide partly protects cultured smooth muscle cells from apoptosis induced by an oxidative stress via activation of ERK1/2 MAPK. Biochim Biophys Acta 2003;1643:65-73.
34. Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM. Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol 2006;26:2511-2518.
35. Mennel HD, Hallier-Neelsen M, Hagner S, Benes L. Two novel cell specific receptor proteins, CRLR and CD 117 in human glial tumors. Clin Neuropathol 2006;25: 107-114.
36. Hagner S, Stahl U, Grimm T, Sturzl M, Lang RE. Expression of calcitonin receptor-like receptor in human vascular tumours. J Clin Pathol 2006;59:1104-1107.
37. Reynolds CM, Eguchi S, Frank GD, Motley ED. Signaling mechanisms of heparin-binding epidermal growth factor-like growth factor in vascular smooth muscle cells. Hypertension 2002;39:525-529.
38. Fujino T, Hasebe N, Fujita M, Takeuchi K, Kawabe J, Tobise K et al. Enhanced expression of heparin-binding EGF-like growth factor and its receptor in hypertrophied left ventricle of spontaneously hypertensive rats. Cardiovasc Res 1998;38:365-374.
39. Schwartz SM, Reidy MA, de Blois D. Factors important in arterial narrowing. J Hypertens Suppl 1996;14:S71-S81.