Endogenous melanocortin system activity contributes to the elevated arterial pressure in spontaneously hypertensive rats

Hypertension

Volumn 51, Issue 4, 2008, Pages 884-890

  Da Silva, Alexandre A ^a,b   Do Carmo, Jussara M ^a,b   Kanyicska, Bela ^b   Dubinion, John ^a,b   Brandon, Elizabeth ^a,b   Hall, John E ^a,b  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Blood pressure; Food intake; Hypertension; Insulin; Leptin; Melanocortin; POMC

Indexed keywords

INSULIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MESSENGER RNA; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; PROPRANOLOL; TERAZOSIN; AGOUTI RELATED PROTEIN; AGOUTI RELATED PROTEIN, RAT; AGOUTI-RELATED PROTEIN, RAT; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIHYPERTENSIVE AGENT; DRUG DERIVATIVE; INTERMEDIN; LEPTIN RECEPTOR; MELANOCORTIN; NEUROPEPTIDE Y; PRAZOSIN; PROOPIOMELANOCORTIN; TERAZOSINE; UNCLASSIFIED DRUG;

ADRENERGIC ACTIVITY; ADRENERGIC RECEPTOR BLOCKING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CANNULA; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; FOOD INTAKE; HEART RATE; HYPERLEPTINEMIA; HYPOTHALAMUS; HYPOTHESIS; INFUSION; INSULIN RESISTANCE; LATERAL BRAIN VENTRICLE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SYMPATHETIC TONE; TELEMETRY; WEIGHT GAIN; WISTAR RAT; ADRENERGIC SYSTEM; ANIMAL; BLOOD PRESSURE; DRUG ANTAGONISM; DRUG EFFECT; EATING; FEMALE; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RENOVASCULAR HYPERTENSION; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ADRENERGIC ALPHA-ANTAGONISTS; AGOUTI-RELATED PROTEIN; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; EATING; FEMALE; HEART RATE; HYPERTENSION, RENAL; HYPOTHALAMUS; MALE; MELANOCORTINS; MELANOCYTE-STIMULATING HORMONES; NEUROPEPTIDE Y; PRAZOSIN; PRO-OPIOMELANOCORTIN; PROPRANOLOL; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, LEPTIN; RNA, MESSENGER; SYMPATHETIC NERVOUS SYSTEM;

EID: 42049103266     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.100636     Document Type: Article

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