메뉴 건너뛰기




Volumn 4, Issue 1, 2012, Pages 43-57

Role of myeloid-derived suppressor cells in tumor immunotherapy

Author keywords

ATRA; cancer; exosome; fluorouracil; gemcitabine; immunotherapy; myeloid derived suppressor cells; sildenafil; STAT3; sunitinib

Indexed keywords

ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; BARDOXOLONE METHYL; BEVACIZUMAB; BISPHOSPHONIC ACID DERIVATIVE; CELECOXIB; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; OXALIPLATIN; PACLITAXEL; RETINOIC ACID; SILDENAFIL; SUNITINIB; TADALAFIL; VARDENAFIL; ZOLEDRONIC ACID;

EID: 83655196899     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.11.154     Document Type: Review
Times cited : (29)

References (105)
  • 1
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion. Science 331, 1565-1570 (2011).
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 2
    • 80053567512 scopus 로고    scopus 로고
    • Cell transfer immunotherapy for metastatic solid cancer- what clinicians need to know
    • Rosenberg SA. Cell transfer immunotherapy for metastatic solid cancer- what clinicians need to know. Nat. Rev. Clin. Oncol. 8, 577-585 (2011).
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 577-585
    • Rosenberg, S.A.1
  • 6
    • 79959680070 scopus 로고    scopus 로고
    • Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth
    • Manrique SZ, Correa MA, Hoelzinger DB et al. Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth. J. Exp. Med. 208, 1485-1499 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 1485-1499
    • Manrique, S.Z.1    Correa, M.A.2    Hoelzinger, D.B.3
  • 7
    • 79953306440 scopus 로고    scopus 로고
    • Tolerogenic pDCs: Spotlight on Foxo3
    • Bronte V. Tolerogenic pDCs: Spotlight on Foxo3. J. Clin. Invest. 121, 1247-1250 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1247-1250
    • Bronte, V.1
  • 8
    • 79953323468 scopus 로고    scopus 로고
    • FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer
    • Watkins SK, Zhu Z, Riboldi E et al. FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer. J. Clin. Invest. 121, 1361-1372 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 1361-1372
    • Watkins, S.K.1    Zhu, Z.2    Riboldi, E.3
  • 9
    • 70350055199 scopus 로고    scopus 로고
    • Arginase: An emerging key player in the mammalian immune system
    • Munder M. Arginase: An emerging key player in the mammalian immune system. Br. J. Pharmacol. 158, 638-651 (2009).
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 638-651
    • Munder, M.1
  • 11
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+ T cells
    • Bronte V, Apolloni E, Cabrelle A et al. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood 96, 3838-3846 (2000).
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3
  • 13
    • 65049084189 scopus 로고    scopus 로고
    • Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
    • Mantovani A, Sica A, Allavena P, Garlanda C, Locati M. Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum. Immunol. 70, 325-330 (2009).
    • (2009) Hum. Immunol. , vol.70 , pp. 325-330
    • Mantovani, A.1    Sica, A.2    Allavena, P.3    Garlanda, C.4    Locati, M.5
  • 15
    • 70350545729 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in inflammation: Uncovering cell subsets with enhanced immunosuppressive functions
    • Bronte V. Myeloid-derived suppressor cells in inflammation: Uncovering cell subsets with enhanced immunosuppressive functions. Eur. J. Immunol. 39, 2670-2672 (2009).
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2670-2672
    • Bronte, V.1
  • 16
    • 77954399377 scopus 로고    scopus 로고
    • Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
    • Sander LE, Sackett SD, Dierssen U et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J. Exp. Med. 207, 1453-1464 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1453-1464
    • Sander, L.E.1    Sackett, S.D.2    Dierssen, U.3
  • 17
    • 62749132318 scopus 로고    scopus 로고
    • Monocyte dependent regulation of autoimmune inflammation
    • Nicholson LB, Raveney BJ, Munder M. Monocyte dependent regulation of autoimmune inflammation. Curr. Mol. Med. 9, 23-29 (2009).
    • (2009) Curr. Mol. Med. , vol.9 , pp. 23-29
    • Nicholson, L.B.1    Raveney, B.J.2    Munder, M.3
  • 18
    • 78650474985 scopus 로고    scopus 로고
    • Bone marrow myeloid-derived suppressor cells MDSCs inhibit graft-versus-host disease GVHD via an arginase-1-dependent mechanism that is up-regulated by interleukin-13
    • Highfill SL, Rodriguez PC, Zhou Q et al. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood 116, 5738-5747 (2010).
    • (2010) Blood , vol.116 , pp. 5738-5747
    • Highfill, S.L.1    Rodriguez, P.C.2    Zhou, Q.3
  • 20
    • 80053421470 scopus 로고    scopus 로고
    • Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
    • Lu T, Ramakrishnan R, Altiok S et al. Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. J. Clin. Invest. 121, 4015-4029 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 4015-4029
    • Lu, T.1    Ramakrishnan, R.2    Altiok, S.3
  • 21
    • 77951258918 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell heterogeneity and subset definition
    • Peranzoni E, Zilio S, Marigo I et al. Myeloid-derived suppressor cell heterogeneity and subset definition. Curr. Opin. Immunol. 22, 238-244 (2010).
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 238-244
    • Peranzoni, E.1    Zilio, S.2    Marigo, I.3
  • 22
    • 68849128500 scopus 로고    scopus 로고
    • Therapeutic targeting of myeloid-derived suppressor cells
    • Ugel S, Delpozzo F, Desantis G et al. Therapeutic targeting of myeloid-derived suppressor cells. Curr. Opin. Pharmacol. 9, 470-481 (2009).
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 470-481
    • Ugel, S.1    Delpozzo, F.2    Desantis, G.3
  • 23
    • 8344273647 scopus 로고    scopus 로고
    • high subset of bone marrow derived granulocytes
    • DOI 10.1093/intimm/dxh169
    • Matzer SP, Rö del F, Strieter RM, Rö llinghoff M, Beuscher HU. Constitutive expression of CXCL2/MIP-2 is restricted to a Gr-1high, CD11b+, CD62Lhigh subset of bone marrow derived granulocytes. Int. Immunol. 16, 1675-1683 (2004). (Pubitemid 39480786)
    • (2004) International Immunology , vol.16 , Issue.11 , pp. 1675-1683
    • Matzer, S.P.1    Rodel, F.2    Strieter, R.M.3    Rollinghoff, M.4    Beuscher, H.U.5
  • 24
    • 77953381239 scopus 로고    scopus 로고
    • Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b+Gr-1+ cells
    • Tomihara K, Guo M, Shin T et al. Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells. J. Immunol. 184, 6151-6160 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 6151-6160
    • Tomihara, K.1    Guo, M.2    Shin, T.3
  • 25
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181, 5791-5802 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 26
  • 27
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • Rodriguez PC, Ernstoff MS, Hernandez C et al. Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res. 69, 1553-1560 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3
  • 28
    • 79951823584 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties
    • Brandau S, Trellakis S, Bruderek K et al. Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. Leukoc. Biol. 89, 311-317 (2011).
    • (2011) Leukoc. Biol. , vol.89 , pp. 311-317
    • Brandau, S.1    Trellakis, S.2    Bruderek, K.3
  • 29
    • 71449127523 scopus 로고    scopus 로고
    • 8+T lymphocytes in patients with advanced-stage non-small-cell lung cancer
    • 8+T lymphocytes in patients with advanced-stage non-small-cell lung cancer. J. Cancer Res. Clin. Oncol. 136, 35-45 (2010).
    • (2010) J. Cancer Res. Clin. Oncol. , vol.136 , pp. 35-45
    • Liu, C.Y.1    Wang, Y.M.2    Wang, C.L.3
  • 31
    • 68249113734 scopus 로고    scopus 로고
    • Increase in frequency of myeloid-derived suppressor cells in mice with spontaneous pancreatic carcinoma
    • Zhao F, Obermann S, von Wasielewski R et al. Increase in frequency of myeloid-derived suppressor cells in mice with spontaneous pancreatic carcinoma. Immunology 128, 141-149 (2009).
    • (2009) Immunology , vol.128 , pp. 141-149
    • Zhao, F.1    Obermann, S.2    Von Wasielewski, R.3
  • 32
    • 67650422616 scopus 로고    scopus 로고
    • The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression
    • Ilkovitch D, Lopez DM. The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression. Cancer Res. 69, 5514-5521 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 5514-5521
    • Ilkovitch, D.1    Lopez, D.M.2
  • 33
    • 79958027925 scopus 로고    scopus 로고
    • Tumor- and organ-dependent infiltration by myeloid-derived suppressor cells
    • Younos I, Donkor M, Hoke T et al. Tumor- and organ-dependent infiltration by myeloid-derived suppressor cells. Int. Immunopharmacol. 11, 816-826 (2011).
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 816-826
    • Younos, I.1    Donkor, M.2    Hoke, T.3
  • 34
    • 65849343816 scopus 로고    scopus 로고
    • Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells
    • Donkor MK, Lahue E, Hoke TA et al. Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells. Int. Immunopharmacol. 9, 937-948 (2009).
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 937-948
    • Donkor, M.K.1    Lahue, E.2    Hoke, T.A.3
  • 35
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage metastatic tumor burden and doxorubicin-cyclophosphamide chemotherapy
    • Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin- cyclophosphamide chemotherapy. Cancer Immunol. Immunother. 58, 49-59 (2009).
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 39
    • 78149270433 scopus 로고    scopus 로고
    • 14+HLA-DR-/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
    • 14+HLA-DR-/ low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand. J. Immunol. 72, 540-547 (2010).
    • (2010) Scand. J. Immunol. , vol.72 , pp. 540-547
    • Brimnes, M.K.1    Vangsted, A.J.2    Knudsen, L.M.3
  • 40
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 182, 4499-4506 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 41
    • 79958068139 scopus 로고    scopus 로고
    • Myeloid cell population dynamics in healthy and tumor-bearing mice
    • Ueha S, Shand FH, Matsushima K. Myeloid cell population dynamics in healthy and tumor-bearing mice. Int. Immunopharmacol. 11, 783-788 (2011).
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 783-788
    • Ueha, S.1    Shand, F.H.2    Matsushima, K.3
  • 42
    • 38049181485 scopus 로고    scopus 로고
    • Reversion of immune tolerance in advanced malignancy: Modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function
    • Pan PY, Wang GX, Yin B et al. Reversion of immune tolerance in advanced malignancy: Modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function. Blood 111, 219-228 (2008).
    • (2008) Blood , vol.111 , pp. 219-228
    • Pan, P.Y.1    Wang, G.X.2    Yin, B.3
  • 43
    • 74249101123 scopus 로고    scopus 로고
    • Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
    • Dolcetti L, Peranzoni E, Ugel S et al. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur. J. Immunol. 40, 22-35 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , pp. 22-35
    • Dolcetti, L.1    Peranzoni, E.2    Ugel, S.3
  • 44
    • 79958032037 scopus 로고    scopus 로고
    • Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSCs expansion
    • Saleem SJ, Conrad DH. Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSCs expansion. Int. Immunopharmacol. 11, 807-813 (2011).
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 807-813
    • Saleem, S.J.1    Conrad, D.H.2
  • 45
    • 77956920766 scopus 로고    scopus 로고
    • Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells
    • Lechner MG, Liebertz DJ, Epstein AL. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J. Immunol. 185, 2273-2284 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 2273-2284
    • Lechner, M.G.1    Liebertz, D.J.2    Epstein, A.L.3
  • 46
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • DOI 10.1038/nri1995, PII NRI1995
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat. Rev. Immunol. 7, 41-51 (2007). (Pubitemid 46020826)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.1 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 47
    • 77951754469 scopus 로고    scopus 로고
    • Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained
    • Ko JS, Rayman P, Ireland J et al. Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res. 70, 3526-3536 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 3526-3536
    • Ko, J.S.1    Rayman, P.2    Ireland, J.3
  • 48
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 49
    • 66949145484 scopus 로고    scopus 로고
    • Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells
    • Corzo CA, Cotter MJ, Cheng P et al. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J. Immunol.182, 5693-5701 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 5693-5701
    • Corzo, C.A.1    Cotter, M.J.2    Cheng, P.3
  • 50
  • 51
    • 64249115813 scopus 로고    scopus 로고
    • Induction of myeloid-derived suppressor cells by tumor exosomes
    • Xiang X, Poliakov A, Liu C et al. Induction of myeloid-derived suppressor cells by tumor exosomes. Int. J. Cancer. 124, 2621-2633 (2009).
    • (2009) Int. J. Cancer. , vol.124 , pp. 2621-2633
    • Xiang, X.1    Poliakov, A.2    Liu, C.3
  • 52
    • 76649097628 scopus 로고    scopus 로고
    • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    • Chalmin F, Ladoire S, Mignot G et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J. Clin. Invest. 120, 457-471 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 457-471
    • Chalmin, F.1    Ladoire, S.2    Mignot, G.3
  • 53
    • 79959856425 scopus 로고    scopus 로고
    • Antigen specificity of immune suppression by myeloid-derived suppressor cells
    • Solito S, Bronte V, Mandruzzato S. Antigen specificity of immune suppression by myeloid-derived suppressor cells. J. Leukoc. Biol. 90, 31-36 (2011).
    • (2011) J. Leukoc. Biol. , vol.90 , pp. 31-36
    • Solito, S.1    Bronte, V.2    Mandruzzato, S.3
  • 54
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • DOI 10.1158/1078-0432.CCR-07-0182
    • Talmadge JE. Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin. Cancer Res. 13, 5243-5248 (2007). (Pubitemid 47510346)
    • (2007) Clinical Cancer Research , vol.13 , Issue.18 , pp. 5243-5248
    • Talmadge, J.E.1
  • 55
    • 77955549860 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity
    • Ostrand-Rosenberg S. Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 59, 1593-1600 (2010).
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 1593-1600
    • Ostrand-Rosenberg, S.1
  • 56
    • 77950829023 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induced by myeloid-derived suppressor cells
    • Nagaraj S, Schrum AG, Cho HI, Celis E, Gabrilovich DI. Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J. Immunol. 184, 3106-3116 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 3106-3116
    • Nagaraj, S.1    Schrum, A.G.2    Cho, H.I.3    Celis, E.4    Gabrilovich, D.I.5
  • 57
    • 79960965896 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice
    • Mundy-Bosse BL, Lesinski GB, Jaime- Ramirez AC et al. Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice. Cancer Res. 71, 5101-5110 (2011).
    • (2011) Cancer Res. , vol.71 , pp. 5101-5110
    • Mundy-Bosse, B.L.1    Lesinski, G.B.2    Jaime- Ramirez, A.C.3
  • 58
    • 41149148269 scopus 로고    scopus 로고
    • Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: Mechanisms and therapeutic perspectives
    • DOI 10.1111/j.1600-065X.2008.00608.x
    • Rodríguez PC, Ochoa AC. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: Mechanisms and therapeutic perspectives. Immunol. Rev. 222, 180-191 (2008). (Pubitemid 351430370)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 180-191
    • Rodriguez, P.C.1    Ochoa, A.C.2
  • 60
    • 31544446571 scopus 로고    scopus 로고
    • + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • DOI 10.1158/0008-5472.CAN-05-1299
    • Huang B, Pan PY, Li Q et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66, 1123-1131 (2006). (Pubitemid 43165981)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 1123-1131
    • Huang, B.1    Pan, P.-Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.-H.8
  • 61
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P, Mgebroff S, Noonan K, Borrello I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68, 5439-5449 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 62
    • 43249130187 scopus 로고    scopus 로고
    • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
    • Movahedi K, Guilliams M, Van den Bossche J et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 111, 4233-4244 (2008).
    • (2008) Blood , vol.111 , pp. 4233-4244
    • Movahedi, K.1    Guilliams, M.2    Van Den Bossche, J.3
  • 63
    • 53349099219 scopus 로고    scopus 로고
    • Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
    • Cheng P, Corzo CA, Luetteke N et al. Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J. Exp. Med. 205, 2235-2249 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2235-2249
    • Cheng, P.1    Corzo, C.A.2    Luetteke, N.3
  • 64
    • 70349240416 scopus 로고    scopus 로고
    • Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
    • Hoechst B, Voigtlaender T, Ormandy L et al. Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor. Hepatology 50, 799-807 (2009).
    • (2009) Hepatology , vol.50 , pp. 799-807
    • Hoechst, B.1    Voigtlaender, T.2    Ormandy, L.3
  • 65
    • 59849126377 scopus 로고    scopus 로고
    • Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-b 1
    • Li H, Han Y, Guo Q, Zhang M, Cao X. Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-b 1. J. Immunol. 182, 240-249 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 240-249
    • Li, H.1    Han, Y.2    Guo, Q.3    Zhang, M.4    Cao, X.5
  • 66
    • 78649610261 scopus 로고    scopus 로고
    • IL-1b regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function
    • Elkabets M, Ribeiro VS, Dinarello CA et al. IL-1b regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur. J. Immunol. 40, 3347-3357 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3347-3357
    • Elkabets, M.1    Ribeiro, V.S.2    Dinarello, C.A.3
  • 67
    • 70350536358 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell activation by combined LPS and IFN-g treatment impairs DC development
    • Greifenberg V, Ribechini E, Rö ssner S, Lutz MB. Myeloid-derived suppressor cell activation by combined LPS and IFN-g treatment impairs DC development. Eur. J. Immunol. 39, 2865-2876 (2009).
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2865-2876
    • Greifenberg, V.1    Ribechini, E.2    Rössner, S.3    Lutz, M.B.4
  • 68
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • Sinha P, Clements VK, Bunt SK, Albelda SM, Ostrand-Rosenberg S. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 179, 977-983 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 70
    • 79251484999 scopus 로고    scopus 로고
    • Prostatectomy restores the maturation competence of blood dendritic cell precursors and reverses the abnormal expansion of regulatory T lymphocytes
    • Brusa D, Carletto S, Cucchiarale G et al. Prostatectomy restores the maturation competence of blood dendritic cell precursors and reverses the abnormal expansion of regulatory T lymphocytes. Prostate 71, 344-352 (2011).
    • (2011) Prostate , vol.71 , pp. 344-352
    • Brusa, D.1    Carletto, S.2    Cucchiarale, G.3
  • 71
    • 80054048551 scopus 로고    scopus 로고
    • Analysis of Treg cell population alterations in the peripheral blood of patients treated surgically for ovarian cancer - A preliminary report
    • Wicherek L, Jozwicki W, Windorbska W et al. Analysis of Treg cell population alterations in the peripheral blood of patients treated surgically for ovarian cancer - a preliminary report. Am. J. Reprod. Immunol. 66(5), 444-450 (2011).
    • (2011) Am. J. Reprod. Immunol. , vol.66 , Issue.5 , pp. 444-450
    • Wicherek, L.1    Jozwicki, W.2    Windorbska, W.3
  • 72
    • 67650083202 scopus 로고    scopus 로고
    • Increased prevalence of regulatory T-cells in the peripheral blood of patients with gastrointestinal cancer
    • Tokuno K, Hazama S, Yoshino S, Yoshida S, Oka M. Increased prevalence of regulatory T-cells in the peripheral blood of patients with gastrointestinal cancer. Anticancer Res. 29, 1527-1532 (2009).
    • (2009) Anticancer Res. , vol.29 , pp. 1527-1532
    • Tokuno, K.1    Hazama, S.2    Yoshino, S.3    Yoshida, S.4    Oka, M.5
  • 74
    • 29244474606 scopus 로고    scopus 로고
    • Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis
    • DOI 10.1158/0008-5472.CAN-05-0045
    • Sinha P, Clements VK, Ostrand-Rosenberg S. Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis. Cancer Res. 65, 11743-11751 (2005). (Pubitemid 41821736)
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11743-11751
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 75
    • 77955771348 scopus 로고    scopus 로고
    • GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells
    • Morales JK, Kmieciak M, Knutson KL, Bear HD, Manjili MH. GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells. Breast Cancer Res. Treat. 123, 39-49 (2010).
    • (2010) Breast Cancer Res. Treat. , vol.123 , pp. 39-49
    • Morales, J.K.1    Kmieciak, M.2    Knutson, K.L.3    Bear, H.D.4    Manjili, M.H.5
  • 77
    • 34548125294 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
    • DOI 10.1158/1078-0432.CCR-07-0409
    • Fricke I, Mirza N, Dupont J et al. Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin. Cancer Res. 13, 4840-4848 (2007). (Pubitemid 47298146)
    • (2007) Clinical Cancer Research , vol.13 , Issue.16 , pp. 4840-4848
    • Fricke, I.1    Mirza, N.2    Dupont, J.3    Lockhart, C.4    Jackson, A.5    Lee, J.-H.6    Sosman, J.A.7    Gabrilovich, D.I.8
  • 78
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
    • DOI 10.1158/0008-5472.CAN-06-4174
    • Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S. Prostaglandin E2 promotes tumor progression by inucing myeloid-derived suppressor cells. Cancer Res. 67, 4507-4513 (2007). (Pubitemid 46815102)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 79
    • 77956473075 scopus 로고    scopus 로고
    • COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma celecoxib influences MDSCs function
    • Veltman JD, Lambers ME, van Nimwegen M et al. COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSCs function. BMC Cancer 10, 464 (2010).
    • (2010) BMC Cancer , vol.10 , pp. 464
    • Veltman, J.D.1    Lambers, M.E.2    Van Nimwegen, M.3
  • 82
    • 37049006066 scopus 로고    scopus 로고
    • Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
    • DOI 10.1158/0008-5472.CAN-07-1882
    • Melani C, Sangaletti S, Barazzetta FM, Werb Z, Colombo MP. Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res. 67, 11438-11446 (2007). (Pubitemid 350248572)
    • (2007) Cancer Research , vol.67 , Issue.23 , pp. 11438-11446
    • Melani, C.1    Sangaletti, S.2    Barazzetta, F.M.3    Werb, Z.4    Colombo, M.P.5
  • 83
    • 25144466458 scopus 로고    scopus 로고
    • + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • DOI 10.1158/1078-0432.CCR-05-0883
    • Suzuki E, Kapoor V, Jassar AS, Kaiser L, Albelda SM. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11, 6713-6721 (2005). (Pubitemid 41339014)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 84
    • 34547630506 scopus 로고    scopus 로고
    • A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
    • Ko HJ, Kim YJ, Kim YS et al. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res. 67, 7477-7486 (2007).
    • (2007) Cancer Res. , vol.67 , pp. 7477-7486
    • Ko, H.J.1    Kim, Y.J.2    Kim, Y.S.3
  • 85
    • 67349133537 scopus 로고    scopus 로고
    • Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
    • Le HK, Graham L, Cha E, Morales JK, Manjili MH, Bear HD. Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int. Immunopharmacol. 9, 900-909 (2009).
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 900-909
    • Le, H.K.1    Graham, L.2    Cha, E.3    Morales, J.K.4    Manjili, M.H.5    Bear, H.D.6
  • 86
    • 77951086882 scopus 로고    scopus 로고
    • 5-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • Vincent J, Mignot G, Chalmin F et al. 5-fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res. 70, 3052-3061 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3
  • 87
    • 77956680680 scopus 로고    scopus 로고
    • A novel chemoimmunomodulating property of docetaxel: Suppression of myeloid-derived suppressor cells in tumor bearers
    • Kodumudi KN, Woan K, Gilvary DL, Sahakian E, Wei S, Djeu JY. A novel chemoimmunomodulating property of docetaxel: Suppression of myeloid-derived suppressor cells in tumor bearers. Clin. Cancer Res. 16, 4583-4594 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , pp. 4583-4594
    • Kodumudi, K.N.1    Woan, K.2    Gilvary, D.L.3    Sahakian, E.4    Wei, S.5    Djeu, J.Y.6
  • 89
    • 58149332680 scopus 로고    scopus 로고
    • Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
    • Kusmartsev S, Su Z, Heiser A et al. Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin. Cancer Res. 14, 8270-8278 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 8270-8278
    • Kusmartsev, S.1    Su, Z.2    Heiser, A.3
  • 92
    • 1642536454 scopus 로고    scopus 로고
    • + T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species
    • 8+T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species. J. Immunol. 172, 989-999 (2004). (Pubitemid 38113758)
    • (2004) Journal of Immunology , vol.172 , Issue.2 , pp. 989-999
    • Kusmartsev, S.1    Nefedova, Y.2    Yoder, D.3    Gabrilovich, D.I.4
  • 93
    • 77949718839 scopus 로고    scopus 로고
    • Antiinflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer
    • Nagaraj S, Youn JI, Weber H et al. Antiinflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clin. Cancer Res. 16, 1812-1823 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , pp. 1812-1823
    • Nagaraj, S.1    Youn, J.I.2    Weber, H.3
  • 94
    • 65549129226 scopus 로고    scopus 로고
    • Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells
    • Xin H, Zhang C, Herrmann A, Du Y, Figlin R, Yu H. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer Res. 69, 2506-2513 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 2506-2513
    • Xin, H.1    Zhang, C.2    Herrmann, A.3    Du, Y.4    Figlin, R.5    Yu, H.6
  • 95
    • 63549105681 scopus 로고    scopus 로고
    • Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
    • Ko JS, Zea AH, Rini BI et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin. Cancer Res. 15, 2148-2157 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 2148-2157
    • Ko, J.S.1    Zea, A.H.2    Rini, B.I.3
  • 96
    • 79958052123 scopus 로고    scopus 로고
    • MDSCs as a mechanism of tumor escape from sunitinib mediated antiangiogenic therapy
    • Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P. MDSCs as a mechanism of tumor escape from sunitinib mediated antiangiogenic therapy. Int. Immunopharmacol. 11, 856-861 (2011).
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 856-861
    • Finke, J.1    Ko, J.2    Rini, B.3    Rayman, P.4    Ireland, J.5    Cohen, P.6
  • 98
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
    • Kusmartsev S, Cheng F, Yu B et al. All-trans-retinoic acid eliminates immature myeloid cells from tumorbearing mice and improves the effect of vaccination. Cancer Res. 63, 4441-4449 (2003). (Pubitemid 36951016)
    • (2003) Cancer Research , vol.63 , Issue.15 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.7
  • 99
    • 80054098093 scopus 로고    scopus 로고
    • Sunitinib facilitates the activation and recruitment of therapeutic antitumor immunity in concert with specific vaccination
    • Bose A, Taylor JL, Alber S et al. Sunitinib facilitates the activation and recruitment of therapeutic antitumor immunity in concert with specific vaccination. Int. J. Cancer 129, 2158-2170 (2011).
    • (2011) Int. J. Cancer , vol.129 , pp. 2158-2170
    • Bose, A.1    Taylor, J.L.2    Alber, S.3
  • 100
    • 77958057373 scopus 로고    scopus 로고
    • Changes in dendritic cell phenotype after a new high-dose weekly schedule of interleukin-2 therapy for kidney cancer and melanoma
    • Finkelstein SE, Carey T, Fricke I et al. Changes in dendritic cell phenotype after a new high-dose weekly schedule of interleukin-2 therapy for kidney cancer and melanoma. J. Immunother. 33, 817-827 (2010).
    • (2010) J. Immunother. , vol.33 , pp. 817-827
    • Finkelstein, S.E.1    Carey, T.2    Fricke, I.3
  • 102
    • 75749147533 scopus 로고    scopus 로고
    • Immunogenic death of colon cancer cells treated with oxaliplatin
    • Tesniere A, Schlemmer F, Boige V et al. Immunogenic death of colon cancer cells treated with oxaliplatin. Oncogene 29, 482-491 (2010).
    • (2010) Oncogene , vol.29 , pp. 482-491
    • Tesniere, A.1    Schlemmer, F.2    Boige, V.3
  • 104
    • 55849130757 scopus 로고    scopus 로고
    • 25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer
    • 25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer. J. Clin. Invest. 118, 3751-3761 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 3751-3761
    • Roux, S.1    Apetoh, L.2    Chalmin, F.3
  • 105
    • 78149330949 scopus 로고    scopus 로고
    • HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
    • Corzo CA, Condamine T, Lu L et al. HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J. Exp. Med. 207, 2439-2453 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 2439-2453
    • Corzo, C.A.1    Condamine, T.2    Lu, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.