Protein histidine [de]phosphorylation in insulin secretion: Abnormalities in models of impaired insulin secretion

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 384, Issue 4-5, 2011, Pages 383-390

  Kowluru, Anjaneyulu ^a   Klumpp, Susanne ^b   Krieglstein, Josef ^b  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Histidine kinases; Histidine phosphatases; Insulin secretion; nm23; Pancreatic islet

Indexed keywords

GLUCOSE; GUANOSINE TRIPHOSPHATE; NUCLEOSIDE DIPHOSPHATE KINASE A; PALMITIC ACID; PROTEIN HISTIDINE KINASE; SMALL INTERFERING RNA;

CELLULAR DISTRIBUTION; INSULIN DEFICIENCY; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW;

ANIMALS; CELLS, CULTURED; HISTIDINE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MODELS, BIOLOGICAL; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION;

EID: 83555161704     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0616-z     Document Type: Review

References (56)

1. LA Alex MI Simon 1994 Protein histidine kinases and signal transduction in prokaryotes and eukaryotes Trends Genet 10 133 138 8029829 10.1016/0168-9525(94)90215-1 1:CAS:528:DyaK2cXmsVyltb0%3D (Pubitemid 24107646)
2. A Alves Cde RA Aguiar AC Alves MA Santana 2007 Diabetes mellitus in patients with cystic fibrosis J Bras Pneumol 33 213 221 17724542 10.1590/S1806-37132007000200017
3. R An YL Chu C Tian XX Dai JH Chen Q Shi J Han XP Dong 2008 Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX1 Acta Pharmacol Sin 29 1451 1458 19026164 10.1111/j.1745-7254.2008.00902.x 1:CAS:528:DC%2BD1MXisFyqtA%3D%3D
4. S Arnaud-Dabernat PM Bourbon A Dierich M Le Meur JY Daniel 2003 Knockout mice as a model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene J Bioenerg Biomembranes 35 19 30 10.1023/A:1023561821551 1:CAS:528:DC%2BD3sXjtVGrur0%3D (Pubitemid 36667577)
5. KA Becker B Tummler E Gulbins H Grassme 2010 Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death Biochem Biophys Res Commun 403 368 374 21078296 10.1016/j.bbrc.2010.11.038 1:CAS:528:DC%2BC3cXhsF2mtL%2FE
6. KA Becker J Riethmuller A Luth G Doring B Kleuser E Gulbins 2010 Acid sphingolyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis Am J Respir Cell Mol Biol 42 716 724 19635928 10.1165/rcmb.2009-0174OC 1:CAS:528:DC%2BC3cXhsVKrtLjI
7. KA Becker J Riethmuller Y Zhang E Gulbins 2010 The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis Open Respir Med J 4 39 47 20556203 1:CAS:528:DC%2BC3cXkvFynt7w%3D
8. PG Besant PV Attwood 2005 Mammalian histidine kinases Biochim Biophys Acta 1754 281 290 16188507 1:CAS:528:DC%2BD2MXhtlags7fN (Pubitemid 41797709)
9. F Cuello RA Schulze F Heemeyer HE Meyer S Lutz KH Jakobs F Niroomand T Wieland 2003 Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) and Gβ subunits. Complex formation of NDPK B with Gβγ dimers and phosphorylation of His-266 in Gβ J Biol Chem 278 7220 7226 12486123 10.1074/jbc.M210304200 1:CAS:528:DC%2BD3sXhsVKisbw%3D (Pubitemid 36800722)
10. L Di S Srivastava O Zhdanova Y Sun Z Li EY Skolnik 2010 Nucleoside diphosphate kinase B knock-out mice have impaired activation of the K+ channel Kca3.1, resulting in defective T cell activation J Biol Chem 285 38765 38771 20884616 10.1074/jbc.M110.168070 1:CAS:528:DC%2BC3cXhsFSmsLbM
11. P Gomes-Alves F Couto C Pesquita AV Coelho D Penque 2010 Rescue of F508del-CFTR by RXR motif inactivation triggers proteome modulation associated with unfolded protein response Biochim Biophys Acta 1804 856 865 20044041 1:CAS:528:DC%2BC3cXis1SjsLY%3D
12. C Guay SR Madiraju A Aumais E Joly M Prentki 2007 A role for ATP citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion J Biol Chem 282 35657 35665 17928289 10.1074/jbc.M707294200 1:CAS:528:DC%2BD2sXhtlKrsb%2FF (Pubitemid 350277124)
13. E Gulbins 2010 Lipids control mucus production in cystic fibrosis Nat Med 16 267 268 20208510 10.1038/nm0310-267 1:CAS:528:DC%2BC3cXivVGqu7c%3D
14. T Higashijima S Uzu T Nakajima EM Ross 1988 Mastoparan, a peptide toxin from wasp venom mimics receptors by activating GTP-binding regulatory proteins (G-proteins) J Biol Chem 263 6491 6494 3129426 1:CAS:528:DyaL1cXitFOmsbg%3D
15. o by mastoparan, related amphiphilic peptides, and hydrophobic amines J Biol Chem 265 14176 14181 2117607 1:CAS:528:DyaK3cXmt1ygsL8%3D
16. HJ Hippe S Lutz F Cuello K Knorr A Vogt KH Jakobs T Wieland F Niroomand 2003 Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) and Gβ subunits. Specific activation of Gsα by an NDPK B-Gβγ complex in H10 cells J Biol Chem 278 7227 7233 12486122 10.1074/jbc.M210305200 1:CAS:528: DC%2BD3sXhsVKisb0%3D (Pubitemid 36800723)
17. HJ Hippe NM Wolf I Abu-Taha R Mehringer S Just S Lutz F Niroomand EH Postel HA Katus W Rottbauer T Wieland 2009 The interaction of nucleoside diphosphate kinase B with Gβγ dimers controls hetrotrimeric G protein activation Proc Natl Acad Sci USA 106 16269 16274 19805292 10.1073/pnas. 0901679106 1:CAS:528:DC%2BD1MXht1KqtbrO
18. HJ Hippe I Abu-Taha NM Wolf HA Katus T Wieland 2011 Through scaffolding and catalytic actions nucleoside diphosphate kinase B differentially regulates basal and β-adrenoreceptor-stimulated cAMP synthesis Cell Signal 23 579 585 21111809 10.1016/j.cellsig.2010.11.010 1:CAS:528:DC%2BC3cXhs1Wnu7fL
19. PM Jones SJ Persaud 1998 Protein kinases, protein phosphorylation, and the regulation of insulin secretion from pancreatic β-cells Endocr Rev 19 429 461 9715374 10.1210/er.19.4.429 1:CAS:528:DyaK1cXlslWlur0%3D (Pubitemid 29116376)
20. JW Joseph ML Odegaard SM Ronnebaum SC Burgess J Muehlbauer AD Sherry CB Newgard 2007 Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion J Biol Chem 282 31592 31600 17823126 10.1074/jbc.M706080200 1:CAS:528:DC%2BD2sXhtFykurfM (Pubitemid 350044870)
21. V Kamath CN Kyathanahalli B Jayaram I Syed K Olson K Ludwig S Klumpp J Krieglstein A Kowluru 2010 Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells Am J Physiol Endocrinol Metab 299 E276 E286 20501872 1:CAS:528:DC%2BC3cXhtVOhtL%2FF
22. S Klumpp J Krieglstein 2002 Phosphorylation and dephosphorylation of histidine residues in proteins Eur J Biochem 269 1067 1071 11856347 10.1046/j.1432-1033.2002.02755.x 1:CAS:528:DC%2BD38XhslOrtbc%3D (Pubitemid 34175364)
23. S Klumpp J Krieglstein 2009 Reversible phosphorylation of histidine residues in proteins from vertebrates Sci Signal 2 pe13 19278958 10.1126/scisignal.261pe13
24. A Kowluru 2002 Identification and characterization of a novel protein histidine kinase in the islet β-cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion Biochem Pharmacol 63 2091 2100 12110368 10.1016/S0006-2952(02)01025-0 1:CAS:528: DC%2BD38XltFSqsLk%3D (Pubitemid 34756674)
25. A Kowluru 2003 Defective protein histidine phosphorylation in islets from the Goto-Kakizaki diabetic rat Am J Physiol Endocrinol Metab 285 E498 E503 12799314 1:CAS:528:DC%2BD3sXnsVGmt7w%3D (Pubitemid 37010826)
26. A Kowluru 2003 Regulatory roles for small G-proteins in the pancreatic beta cell: lessons from models of impaired insulin secretion Am J Physiol Endocrinol Metab 285 E669 E684 12959934 1:CAS:528:DC%2BD3sXosV2rur4%3D (Pubitemid 37176417)
27. A Kowluru 2005 Novel regulatory roles for protein phosphatase-2A in the islet beta cell Biochem Pharmacol 69 1681 1691 15935144 10.1016/j.bcp.2005.03. 018 1:CAS:528:DC%2BD2MXltVOnsrk%3D (Pubitemid 40780068)
28. A Kowluru 2008 Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell J Cell Mol Med 12 1885 1908 18400053 10.1111/j.1582-4934.2008.00330.x 1:CAS:528: DC%2BD1cXhsVOgu73N
29. A Kowluru 2011 Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches Biochem Pharmacol 10.1016/j.bcp.2011.01.013
30. A Kowluru SA Metz 1994 Characterization of nucleoside diphosphokinase activity in human and rodent pancreatic β cells: evidence for its role in the formation of guanosine triphosphate, a permissive factor for nutrient-induced insulin secretion Biochemistry 33 12495 12503 7918472 10.1021/bi00207a017 1:CAS:528:DyaK2cXmt1OjsLo%3D (Pubitemid 24340456)
31. A Kowluru SE Seavey CJ Rhodes SA Metz 1996 A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta-cells Biochem J 313 97 108 8546716 1:CAS:528:DyaK28XivVOnuw%3D%3D
32. S Kowluru SE Seavey G Li RL Sorenson AJ Weinhaus R Nesher ME Rabaglia J Vadakekalam SA Metz 1996 Glucose- and GTP-dependent stimulation of the carboxyl methylation of Cdc42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion J Clin Invest 98 540 555 8755667 10.1172/JCI118822 1:CAS:528:DyaK28XksFClt7s%3D (Pubitemid 26255756)
33. A Kowluru G Li SA Metz 1997 Glucose activates the carboxylmethylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin J Clin Invest 100 1596 1610 9294129 10.1172/JCI119684 1:CAS:528:DyaK2sXmt1Cqtrk%3D (Pubitemid 27425788)
34. A Kowluru M Tannous HQ Chen 2002 Localization and characterization of the mitochiondrial isoform of the nucleoside diphosphate kinase in the pancreatic β-cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase Arch Biochem Biophys 398 160 169 11831846 10.1006/abbi.2001.2710 1:CAS:528:DC%2BD38XhtVajt7k%3D (Pubitemid 34848582)
35. A Kowluru R Veluthakal DM Kaetzel 2006 Regulatory roles for nm23/nucleoside diphophate kinase-like enzymes in insulin secretion from the pancreatic islet beta cell J Bioenerg Biomembr 38 227 232 16957985 10.1007/s10863-006-9038-x 1:CAS:528:DC%2BD28XhtlShsLrM (Pubitemid 44946230)
36. TA Laguna BM Nathan A Moran 2010 Managing diabetes in cystic fibrosis Diab Obes Metab 12 858 864 10.1111/j.1463-1326.2010.01250.x 1:STN:280: DC%2BC3cfnt1WisA%3D%3D
37. E Le J Jeong SE Kim EJ Song SW Kang K-J Lee 2009 Multiple functions of nm23-H1 are regulated by oxido-reduction system PlosOne 4 1 14
38. MJ MacDonald 1990 Elusive proximal signals of beta-cells for insulin secretion Diabetes 39 1461 1466 2245873 10.2337/diabetes.39.12.1461 1:CAS:528:DyaK3MXhvF2ksbg%3D
39. MJ MacDonald AD Smith III NM Hasan G Sabat LA Fahein 2007 Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell J Biol Chem 282 30596 30606 17724028 10.1074/jbc.M702732200 1:CAS:528:DC%2BD2sXhtFGgsrbF (Pubitemid 350035194)
40. HR Matthews 1995 Protein kinases and phosphatases that act on histidine, lysine, or arginine residues in eukaryotic proteins: a possible regulator of the mitogen activated protein kinase cascade Pharmacol Ther 67 323 350 8577821 10.1016/0163-7258(95)00020-8 1:CAS:528:DyaK2MXptVahs7o%3D
41. SA Metz 1991 The pancreatic islet as a Rubik's cube. Is phospholipid hydrolysis a piece of the puzzle Diabetes 40 1565 1573 1756897 10.2337/diabetes.40.12.1565 1:CAS:528:DyaK38XltFKmug%3D%3D
42. SA Metz ME Rabaglia Pintar 1992 Selective inhibitors of GTP synthesis impede exocytotic insulin release from intact rat islets J Biol Chem 267 12517 12527 1352288 1:CAS:528:DyaK38XkvVersLc%3D
43. SA Metz M Meredith ME Rabaglia A Kowluru 1993 Small elevations of glucose concentration redirect and amplify the synthesis of guanosine 5′-triphosphate in rat islets J Clin Invest 92 872 882 8349822 10.1172/JCI116662 1:CAS:528:DyaK2cXps1CmtQ%3D%3D (Pubitemid 23262410)
44. SA Metz ME Meredith J Vadakekalam ME Rabaglia A Kowluru 1999 A defect late in stimulus-secretion coupling impairs insulin secretion in Goto Kakizaki diabetic rats Diabetes 48 1754 1762 10480605 10.2337/diabetes.48.9.1754 1:CAS:528:DyaK1MXmtVaitLw%3D (Pubitemid 29415194)
45. R Nesher E Anteby M Yedozvizky N Warwar E Cerasi 2002 Beta-cell protein kinases and the dynamics of the insulin response to glucose Diabetes 51 suppl 1 S63 S73
46. CB Newgard JD McGarry 1995 Metabolic coupling factors in pancreatic β-cell signal transduction Annu Rev Biochem 64 689 719 7574498 10.1146/annurev.bi.64.070195.003353 1:CAS:528:DyaK2MXmsl2qtrs%3D
47. EK Pia G Pettersson EK Bo F Gong JP Li O Zetterqvist 2002 Identification and characterization of mammalian 14-kDa phosphohistidine phosphatase Eur J Biochem 269 5016 5023 10.1046/j.1432-1033.2002.03206.x (Pubitemid 35279015)
48. M Prentki FM Matschinsky 1987 Calcium, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion Physiol Rev 67 1223 1226
49. PS Steeg D Palmieri T Ouatas M Salerno 2003 Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer Can Lett 190 1 12 10.1016/S0304-3835(02)00499-8 1:CAS:528: DC%2BD3sXltFKntw%3D%3D (Pubitemid 36106550)
50. I Subasinghe I Syed A Kowluru 2011 Phagocyte-like NADPH oxidase promotes cytokine mitochondrial dysfunction in pancreatic beta-cells: evidence for regulation by Rac1 Am J Physiol Regul Integr Comp Physiol 300 R21-20 10.1152/ajpregu.00421.2010
51. I Syed B Jayaram W Subasinghe A Kowluru 2010 Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid hydroperoxides and the loss in mitochondrial membrane potential in pancreatic beta-cells Biochem Pharmacol 80 874 883 20493824 10.1016/j.bcp.2010. 05.006 1:CAS:528:DC%2BC3cXptVCnsLc%3D
52. S Tofe JC Moreno L Maiz M Alonso H Escobar R Barrio 2005 Insulin-secretion abnormalities and clinical deterioration related to impaired glucose tolerance in cystic fibrosis Eur J Endocrinol 152 241 247 15745932 10.1530/eje.1.01836 1:CAS:528:DC%2BD2MXit1WhtrY%3D (Pubitemid 40309571)
53. R Veluthakal R Palanivel Y Zhao P McDonald S Gruber A Kowluru 2005 Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: potential mechanisms underlying ceramide-mediated metabolic dysfunction of the beta-cell Apoptosis 10 841 850 16133874 10.1007/s10495-005-0431-4 1:CAS:528:DC%2BD2MXotFenurY%3D (Pubitemid 41187082)
54. R Veluthakal MV Suresh A Kowluru 2009 Down-regulation of expression and function of nucleodide diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicity Mol Cell Biochem 329 121 129 19367376 10.1007/s11010-009-0113-6 1:CAS:528:DC%2BD1MXpsValt7g%3D
55. T Wieland B Nunberg I Ulibarri S Kaldenberg-Stasch G Schultz KH Jakobs 1993 Guanine nucleotide-specific phosphate transfer by guanine-binding regulatory protein beta-subunits. Characterization of phosphorylated amino acids J Biol Chem 268 18111 18118 8349688 1:CAS:528:DyaK3sXmt1Sitrs%3D (Pubitemid 23260331)
56. T Wieland HJ Hippe K Ludwig XB Zhou M Korth S Klumpp 2010 Reversible histidine phosphorylation in mammalian cells: a teeter-totter formed by nucleoside diphosphate kinase and protein histidine phosphatase 1 Meth Enzymol 471 379 402 20946858 10.1016/S0076-6879(10)71020-X 1:CAS:528: DC%2BC3cXmtlSgtb4%3D