Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX1

Acta Pharmacologica Sinica

Volumn 29, Issue 12, 2008, Pages 1451-1458

  An, Run ^a,b   Chu, Yong Lie ^a   Tian, Chan ^b   Dai, Xiao Xia ^a   Chen, Jing Hong ^a   Shi, Qi ^b   Han, Jim ^b   Dong, Xiao Ping ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Cell viability; GPX1; nm23 Hl; Oxidative stress; p53; Reactive oxygen species

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GLUTATHIONE PEROXIDASE 1; NUCLEOSIDE DIPHOSPHATE KINASE A; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRYPTOPHAN; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; NME1 PROTEIN, HUMAN; NUCLEOSIDE DIPHOSPHATE KINASE NM23; OXIDIZING AGENT;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LEVEL; CELL PROTECTION; CELL VIABILITY; CLONE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PLASMID; ANIMAL; GENETICS; METABOLISM;

ANIMALS; GLUTATHIONE PEROXIDASE; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 64549125656     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00902.x     Document Type: Article

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