Effects of acetyl salycilic acid and ibuprofen in chronic liver damage induced by CCl 4

Journal of Applied Toxicology

Volumn 32, Issue 1, 2012, Pages 51-59

  Chávez, Enrique ^a   Castro Sánchez, Luis ^a   Shibayama, Mineko ^a   Tsutsumi, Victor ^a   Pérez Salazar, Eduardo ^a   Moreno, Mario G ^a   Muriel, Pablo ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

COX; Fibrosis; Metalloproteinases; NF B; NSAIDs

Indexed keywords

ACETYLSALICYLIC ACID; CARBON TETRACHLORIDE; COLLAGEN; COLLAGENASE 3; CYCLOOXYGENASE 2; DRUG VEHICLE; GELATINASE A; GELATINASE B; GLUTATHIONE; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CHRONIC DISEASE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL RAT; GENE TRANSLOCATION; LIPID PEROXIDATION; LIVER FIBROSIS; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WISTAR RAT;

ANIMALS; ASPIRIN; BLOTTING, WESTERN; CARBON TETRACHLORIDE; CELL NUCLEUS; CHRONIC DISEASE; COLLAGEN; CYCLOOXYGENASE 2 INHIBITORS; GLUTATHIONE; IBUPROFEN; LIPID PEROXIDATION; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; LIVER FUNCTION TESTS; MALE; MATRIX METALLOPROTEINASES; NF-KAPPA B; OXIDATION-REDUCTION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN TRANSPORT; RATS; RATS, WISTAR;

EID: 83455235539     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1638     Document Type: Article

References (44)

1. Arthur MJ. 2000. Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G245-249.
2. Bergmeyer HU, Grabl M, Walter HE. 1983. Enzymes. In Methods of Enzymatic Analysis, Bergmeyer J, Grabl M (eds). Verlag-Chemie: Weinheim; 269-270.
3. Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA. 1993. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4: 197-250.
4. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254.
5. Cazanave S, Vadrot N, Tinel M, Berson A, Lettéron P, Larosche I, Descatoire V, Feldmann G, Robin MA, Pessayre D. 2008. Ibuprofen administration attenuates serum TNF-alpha levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation. Toxicol. Appl. Pharmacol. 231: 336-343.
6. 4 in the rat. Liver Int. 7: 969-978.
7. Dabhi JK, Solanki JK, Mehta A. 2008. Antiatherosclerotic activity of ibuprofen, a non-selective COX inhibitor - an animal study. Indian J. Exp. Biol. 46: 476-481.
8. Dieter P, Scheibe R, Jakobsson P, Watanabe K, Kolada A, Kamionka S. 2000. Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages. Biochem. Biophys. Res. Commun. 276: 488-492.
9. Dyer RB, Hersog NK. 1995. Isolation of intact nuclei for nuclear extract preparation from a fragile B lymphocyte cell line. Biotechniques 19: 192-195.
10. Elsharkawy AM, Mann DA. 2007. Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis. Hepatology 46: 590-597.
11. Enomoto N, Ikejima K, Yamashina S, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Schemmer P, Bradford BU, Rivera CA, Zhong Z, Thurman RG. 2000. Kupffer cell-derived prostaglandin E(2) is involved in alcohol-induced fat accumulation in rat liver. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G100-106.
12. Etique N, Grillier-Vuissoz I, Flament S. 2006. Ethanol stimulates the secretion of matrix metalloproteinases 2 and 9 in MCF-7 human breast cancer cells. Oncol. Rep. 15: 603-608.
13. García-Tovar CG, Perez A, Luna J, Mena R, Osorio B, Aleman V, Mondragon R, Mornet D, Rendón A, Hernandez JM. 2001. Biochemical and histochemical analysis of 71kDa dystrophin isoform (Dp71f) in rat brain. Acta Histochem. 103: 209-224.
14. Glossman M, Neville DM. 1972. Glutamyl transferase in kidney brush border membranes. FEBS Lett. 19: 340-344.
15. Gressner AM, Weiskirchen R. 2006. Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J. Cell. Mol. Med. 10: 76-99.
16. Heussen C, Dowdle EB. 1980. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal. Biochem. 102: 196-202.
17. Hissin PJ, Hilf RA. 1976. Fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74: 214-226.
18. Kerkvliet EH, Docherty AJ, Beertsen W, Everts V. 1999. Collagen breakdown in soft connective tissue explants is associated with the level of active gelatinase A (MMP-2) but not with collagenase. Matrix Biol. 18: 373-380.
19. Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ, Chung HY. 2002. NF-kappa B binding activity and cyclooxygenase-2 expression in persistent CCl(4)-treated rat liver injury. J. Korean Med. Sci. 17: 193-200.
20. Knittel T, Mehde M, Kobold D, Saile B, Dinter C, Ramadori G. 1999. Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1. J. Hepatol. 30: 48-60.
21. Knittel T, Mehde M, Grundmann A, Saile B, Scharf JG, Ramadori G. 2000. Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat. Histochem. Cell Biol. 113: 443-453.
22. Liu H, Peng Y, Liu F, Li J, Chen X, Liu Y, Zhang H. 2007. A selective cyclooxygenase-2 inhibitor decreases transforming growth factor-β1 synthesis and matrix production in human peritoneal mesothelial cells. Cell Biol. Int. 31: 508-515.
23. Mitchell JA, Warner TD. 1999. Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Rev. Br. J. Pharmacol. 128: 1121-1132.
24. Mohammed NA, Abd El-Aleem SA, El-Hafiz HA, McMahon RF. 2004. Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: a possible role for COX-2 in the pathogenesis of liver cirrhosis. J. Clin. Pathol. 57: 350-354.
25. Muriel P. 1997. Peroxidation of lipids and liver damage. In Antioxidants, Oxidants, and Free Radicals, Baskin SI, Salem H, (eds). Taylor & Francis: Washington, DC; 237-257.
26. Muriel P, Moreno MG, Hernández M del C, Chávez E, Alcantar LK. 2005. Resolution of liver fibrosis in chronic CCl4 administration in the rat after discontinuation of treatment: effect of silymarin, silibinin, colchicine and trimethylcolchicinic acid. Basic Clin. Pharmacol. Toxicol. 96: 375-380.
27. Nanji AA, Miao L, Thomas P, Rahemtulla A, Khwaja S, Zhao S, Peters D, Tahan SR, Dannenberg AJ. 1997. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. Gastroenterology 113: 1811-1182.
28. Neubauer K, Saile B, Ramadori G. 2001. Liver fibrosis and altered matrix synthesis. Can. J. Gastroenterol. 15: 187-193.
29. Okawa H, Ohmishi N, Yagi K. 1979. Assay for lipid peroxides in animal tissues by the thiobarbituric acid reaction. Anal. Biochem. 95: 351-358.
30. 4 and adequate model of human cirrhosis? Hepatology 3: 112-120.
31. Prockop DJ, Underfriend S. 1960. A specific method for the analysis of hydroxyproline in tissues and urine. Anal. Biochem. 1: 228-239.
32. Püschel GP, Kirchner C, Schröder A, Jungermann K. 1993. Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathways. Eur. J. Biochem. 218: 1083-1089.
33. Ramírez-Yañez GO, Hamlet S, Jonarta A, Seymour GJ, Symons AL. 2006. Prostaglandin E2 enhances transforming growth factor-beta 1 and TGF-beta receptors synthesis: an in vivo and in vitro study. Prostaglandins Leukot. Essent. Fatty Acids 74: 183-192.
34. Reitman S, Frankel S. 1957. A colorimetric method for determination of serum oxaloacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28: 56-63.
35. Rosen H, Keeffe E. 2000. Evaluation of abnormal liver enzymes, use of liver tests, and the serology of viral hepatitis. In Liver Disease: Diagnosis and Management, Bacon B, DiBisceglie AM (eds). Plenum Press: New York; 24-35.
36. Sagone AL, Husney RM. 1987. Oxidation of salicylates by stimulated granulocytes: evidence that these drugs act as free radical scavengers in biological systems. J. Immunol. 138: 2177-2183.
37. Sentíes-Gómez M, Gálvez-Gastélum F, Meza-García E, Armendáriz-Borunda J. 2004. Fibrosis hepática. El papel de las metaloproteinasas y de TGF-β. Gac. Méd. Méx. 141: 315-321.
38. Takada Y, Bhardwaj A, Potdar P, Aggarwal BB. 2004. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene 23: 9247-9258.
39. Van Lieshout EM, Tiemessen DM, Peters WH, Jansen JB. 1997. Effects of nonsteroidal anti-inflammatory drugs on glutathione S-transferases of the rat digestive tract. Carcinogenesis 18: 485-490.
40. Vane JR, Bakhle YS, Botting RM. 1998. Cyclooxygenases 1 and 2. Annu. Rev. Pharmacol. Toxicol. 38: 97-120.
41. Watanabe T, Niioka M, Hozawa S, Kameyama K, Hayashi T, Arai M, Ishikawa A, Maruyama K, Okazaki I. 2000. Gene expression of interstitial collagenase in both progressive and recovery phase of rat liver fibrosis induced by carbon tetrachloride. J. Hepatol. 33: 224-235.
42. Weber L, Boll M, Stampfl A. 2003. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit. Rev. Toxicol. 33: 105-136.
43. Yamamoto H, Kondo M, Nakamori S, Nagano H, Wakasa K, Sugita Y, Chang-De J, Kobayashi S, Damdinsuren B, Dono K, Umeshita K, Sekimoto M, Sakon M, Matsuura N, Monden M. 2003. JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis. Gastroenterology 125: 556-571.
44. Yin MJ, Yamamoto Y, Gaynor RB. 1998. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature 396: 77-80.