메뉴 건너뛰기




Volumn 360, Issue 1-2, 2012, Pages 205-214

Acute hyperhomocysteinemia alters the coagulation system and oxidative status in the blood of rats

Author keywords

Coagulation system; Homocysteine; Nitric oxide; Oxidative stress

Indexed keywords

CATALASE; FIBRINOGEN; GLUTATHIONE PEROXIDASE; HOMOCYSTEINE; NITRITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 83455234786     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1058-0     Document Type: Article
Times cited : (14)

References (71)
  • 3
    • 0033028586 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, atherosclerosis and thrombosis
    • M Cattaneo 1999 Hyperhomocysteinemia, atherosclerosis and thrombosis Thromb Haemost 81 165 176 10063987 1:CAS:528:DyaK1MXhvVGrtL4%3D (Pubitemid 29078298)
    • (1999) Thrombosis and Haemostasis , vol.81 , Issue.2 , pp. 165-176
    • Cattaneo, M.1
  • 4
    • 0041694331 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and its role in the development of atherosclerosis
    • DOI 10.1016/S0009-9120(03)00062-6
    • AB Lawrence de Koning GH Werstuck J Zhou RC Austin 2003 Hyperhomocysteinemia and its role in the development of atherosclerosis Clin Biochem 36 431 441 12951169 10.1016/S0009-9120(03)00062-6 1:STN:280: DC%2BD3svhtFChsg%3D%3D (Pubitemid 37086702)
    • (2003) Clinical Biochemistry , vol.36 , Issue.6 , pp. 431-441
    • Lawrence De Koning, A.B.1    Werstuck, G.H.2    Zhou, J.3    Austin, R.C.4
  • 5
    • 0036590637 scopus 로고    scopus 로고
    • Homocysteine and arterial disease: Experimental mechanisms
    • DOI 10.1016/S1537-1891(02)00254-9, PII S1537189102002549
    • JW Cook LM Taylor SL Orloff GJ Landry GL Moneta JM Porter 2002 Homocysteine and arterial disease Exper Mech Vascul Pharmacol 38 293 300 10.1016/S1537-1891(02)00254-9 1:CAS:528:DC%2BD38XnvFKitLg%3D (Pubitemid 36398263)
    • (2002) Vascular Pharmacology , vol.38 , Issue.5 , pp. 293-300
    • Cook, J.W.1    Taylor, L.M.2    Orloff, S.L.3    Landry, G.J.4    Moneta, G.L.5    Porter, J.M.6
  • 6
    • 31744435763 scopus 로고    scopus 로고
    • Effect of homocysteine on platelet activation induced by collagen
    • DOI 10.1016/j.msea.2006.06.093, PII S0899900705002352
    • F Luo X Liu S Wang H Chen 2006 Effect of homocysteine on platelet activation induced by collagen Nutrition 22 69 75 16455445 10.1016/j.nut.2005. 04.012 (Pubitemid 43175787)
    • (2006) Nutrition , vol.22 , Issue.1 , pp. 69-75
    • Luo, F.1    Liu, X.2    Wang, S.3    Chen, H.4
  • 7
    • 1642422357 scopus 로고    scopus 로고
    • Blood coagulation tests in toxicological studies - Review of methods and their significance for drug safety assessment
    • DOI 10.2131/jts.29.13
    • M Kurata I Horii 2004 Blood coagulation tests in toxicological studies-review of methods and their significance for drug safety assessment J Toxicol Sci 29 13 32 15018151 10.2131/jts.29.13 1:CAS:528:DC%2BD2cXjvFGqt7g%3D (Pubitemid 38405094)
    • (2004) Journal of Toxicological Sciences , vol.29 , Issue.1 , pp. 13-32
    • Kurata, M.1    Horii, I.2
  • 8
    • 0037337219 scopus 로고    scopus 로고
    • The coagulation system
    • DOI 10.1097/00041327-200303000-00011
    • V Biousse 2003 The coagulation system J Neuroophthalmol 23 50 62 12616090 10.1097/00041327-200303000-00011 (Pubitemid 36292816)
    • (2003) Journal of Neuro-Ophthalmology , vol.23 , Issue.1 , pp. 50-62
    • Biousse, V.1
  • 9
    • 34249086607 scopus 로고    scopus 로고
    • Mechanisms of homocysteine toxicity in humans
    • DOI 10.1007/s00726-006-0432-9, Special Issue: Focus on Amino Acid and Protein Modification by Oxygen and Nitrogen Species
    • J Perla-Kajan T Twardowski H Jakubowski 2007 Mechanisms of homocysteine toxicity in humans Amino Acids 32 561 572 17285228 10.1007/s00726-006-0432-9 1:CAS:528:DC%2BD2sXlsVGnsb4%3D (Pubitemid 46790938)
    • (2007) Amino Acids , vol.32 , Issue.4 , pp. 561-572
    • Perla-Kajan, J.1    Twardowski, T.2    Jakubowski, H.3
  • 11
    • 0034887928 scopus 로고    scopus 로고
    • Homocysteine-induced inhibition of nitric oxide production in platelets: A study on healthy and diabetic subjects
    • DOI 10.1007/s001250100581
    • B Mutus RA Rabini R Staffolani R Ricciotti P Fumelli N Moretti D Martarelli L Mazzanti 2001 Homocysteine-induced inhibition of nitric oxide production in platelets: a study on healthy and diabetic subjects Diabetologia 44 979 982 11484074 10.1007/s001250100581 1:CAS:528:DC%2BD3MXlsFCgsLo%3D (Pubitemid 32778129)
    • (2001) Diabetologia , vol.44 , Issue.8 , pp. 979-982
    • Mutus, B.1    Rabini, R.A.2    Staffolani, R.3    Ricciotti, R.4    Fumelli, P.5    Moretti, N.6    Martarelli, D.7    Mazzanti, L.8
  • 12
    • 0036995647 scopus 로고    scopus 로고
    • Effect of homocysteine on arachidonic acid release in human platelets
    • DOI 10.1046/j.1365-2362.2002.00971.x
    • M Signorello R Pascale G Leoncini 2002 Effect of homocysteine on arachidonic acid release in human platelets Eur J Clin Invest 32 279 284 11952814 10.1046/j.1365-2362.2002.00971.x 1:CAS:528:DC%2BD38XjvFGisrw%3D (Pubitemid 36216594)
    • (2002) European Journal of Clinical Investigation , vol.32 , Issue.4 , pp. 279-284
    • Signorello, M.G.1    Pascale, R.2    Leoncini, G.3
  • 13
    • 0033566951 scopus 로고    scopus 로고
    • Nitric oxide and the proliferation of vascular smooth muscle cells
    • DOI 10.1016/S0008-6363(99)00171-6, PII S0008636399001716
    • JY Jeremy D Rowe AM Emsley AC Newby 1999 Nitric oxide and the proliferation of vascular smooth muscle cells Cardiovasc Res 43 580 594 10690330 10.1016/S0008-6363(99)00171-6 1:CAS:528:DyaK1MXlslCks7s%3D (Pubitemid 29369257)
    • (1999) Cardiovascular Research , vol.43 , Issue.3 , pp. 580-594
    • Jeremy, J.Y.1    Rowe, D.2    Emsley, A.M.3    Newby, A.C.4
  • 14
    • 0038509956 scopus 로고    scopus 로고
    • In vitro effect of homocysteine on some parameters of oxidative stress in rat hippocampus
    • DOI 10.1023/A:1023815119931
    • EL Streck PS Vieira CM Wannmacher C Dutra-Filho M Wajner AT Wyse 2003 In vitro effect of homocysteine on some parameters of oxidative stress in rat hippocampus Metab Brain Dis 18 147 154 12822833 10.1023/A:1023815119931 1:CAS:528:DC%2BD3sXjvVagsbg%3D (Pubitemid 36718127)
    • (2003) Metabolic Brain Disease , vol.18 , Issue.2 , pp. 147-154
    • Streck, E.L.1    Vieira, P.S.2    Wannmacher, C.M.D.3    Dutra-Filho, C.S.4    Wajner, M.5    Wyse, A.T.S.6
  • 17
    • 79952771094 scopus 로고    scopus 로고
    • Homocysteine induces oxidative-nitrative stress in heart of rats: Prevention by folic acid
    • 21076891 10.1007/s12012-010-9094-7 1:CAS:528:DC%2BC3MXhs1CqtLc%3D
    • J Kolling EB Scherer AA da Cunha MJ da Cunha AT Wyse 2011 Homocysteine induces oxidative-nitrative stress in heart of rats: prevention by folic acid Cardiovasc Toxicol 11 67 73 21076891 10.1007/s12012-010-9094-7 1:CAS:528:DC%2BC3MXhs1CqtLc%3D
    • (2011) Cardiovasc Toxicol , vol.11 , pp. 67-73
    • Kolling, J.1    Scherer, E.B.2    Da Cunha, A.A.3    Da Cunha, M.J.4    Wyse, A.T.5
  • 19
    • 77955502645 scopus 로고    scopus 로고
    • Fructose-1, 6-bisphosphate inhibits in vitro and ex vivo platelet aggregation induced by ADP and ameliorates coagulation alterations in experimental sepsis in rats
    • 19705256 10.1007/s11239-009-0387-2 1:CAS:528:DC%2BC3cXlvVehu70%3D
    • LM de Oliveira MG Pires AB Magrisso TP Munhoz R Roesler JR de Oliveira 2010 Fructose-1, 6-bisphosphate inhibits in vitro and ex vivo platelet aggregation induced by ADP and ameliorates coagulation alterations in experimental sepsis in rats J Thromb Thrombolysis 29 387 394 19705256 10.1007/s11239-009-0387-2 1:CAS:528:DC%2BC3cXlvVehu70%3D
    • (2010) J Thromb Thrombolysis , vol.29 , pp. 387-394
    • De Oliveira, L.M.1    Pires, M.G.2    Magrisso, A.B.3    Munhoz, T.P.4    Roesler, R.5    De Oliveira, J.R.6
  • 21
    • 0020448709 scopus 로고
    • 15N]nitrate in biological fluids
    • DOI 10.1016/0003-2697(82)90118-X
    • LC Green DA Wagner J Glogowski PL Skipper JS Wishnok SR Tannenbaum 1982 Analysis of nitrate, nitrite and [15 N]nitrate in biological fluids Anal Biochem 126 131 138 7181105 10.1016/0003-2697(82)90118-X 1:CAS:528:DyaL38XlvFGgtLY%3D (Pubitemid 13203451)
    • (1982) Analytical Biochemistry , vol.126 , Issue.1 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 22
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • H Ohkawa N Ohishi K Yagi 1979 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal Biochem 95 351 358 36810 10.1016/0003-2697(79)90738-3 1:CAS:528:DyaE1MXksFaisbk%3D (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 23
  • 24
    • 0021318441 scopus 로고
    • Catalase, in vitro
    • 6727660 10.1016/S0076-6879(84)05016-3 1:CAS:528:DyaL2cXltVKis7s%3D
    • H Aebi 1984 Catalase, in vitro Methods Enzymol 105 121 126 6727660 10.1016/S0076-6879(84)05016-3 1:CAS:528:DyaL2cXltVKis7s%3D
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 25
    • 0019740344 scopus 로고
    • Glutathione peroxidase
    • 7329310 10.1016/S0076-6879(81)77046-0 1:CAS:528:DyaL38XhtFOrur0%3D
    • A Wendel 1981 Glutathione peroxidase Methods Enzymol 77 325 333 7329310 10.1016/S0076-6879(81)77046-0 1:CAS:528:DyaL38XhtFOrur0%3D
    • (1981) Methods Enzymol , vol.77 , pp. 325-333
    • Wendel, A.1
  • 26
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • 14907713 1:CAS:528:DyaG38XhsVyrsw%3D%3D
    • OH Lowry NJ Rosebrough AL Farr RJ Randal 1951 Protein measurement with the folin phenol reagent J Biol Chem 193 265 275 14907713 1:CAS:528: DyaG38XhsVyrsw%3D%3D
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randal, R.J.4
  • 27
    • 0033822421 scopus 로고    scopus 로고
    • Homocysteine, coagulation, platelet function, and thrombosis
    • 11011842 10.1055/s-2000-8469 1:CAS:528:DC%2BD3cXntV2hsrg%3D
    • A Coppola G Davi V De Stefano FP Mancini AM Cerbone G Di Minno 2000 Homocysteine, coagulation, platelet function, and thrombosis Semin Thromb Hemost 26 243 254 11011842 10.1055/s-2000-8469 1:CAS:528:DC%2BD3cXntV2hsrg%3D
    • (2000) Semin Thromb Hemost , vol.26 , pp. 243-254
    • Coppola, A.1    Davi, G.2    De Stefano, V.3    Mancini, F.P.4    Cerbone, A.M.5    Di Minno, G.6
  • 28
    • 0018858624 scopus 로고
    • Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury
    • RT Wall JM Harlan LA Harker GE Striker 1980 Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury Thromb Res 18 113 121 7404495 10.1016/0049-3848(80)90175-9 1:CAS:528: DyaL3cXksVeju78%3D (Pubitemid 10109903)
    • (1980) Thrombosis Research , vol.18 , Issue.1-2 , pp. 113-121
    • Wall, R.T.1    Harlan, J.M.2    Harker, L.A.3    Striker, G.E.4
  • 29
    • 0036120318 scopus 로고    scopus 로고
    • Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion
    • DOI 10.1161/01.ATV.0000014221.30108.08
    • MD Silverman RJ Tumuluri M Davis G Lopez JT Rosenbaum PI Lelkes 2002 Homocysteine unregulates vascular cell adhesion molecule-1 expression in cultured aortic endothelial cells and enhances monocyte adhesion Arterioscler Thromb Vasc Biol 22 587 592 11950695 10.1161/01.ATV.0000014221.30108.08 1:CAS:528:DC%2BD38XjtVOru74%3D (Pubitemid 34408738)
    • (2002) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.22 , Issue.4 , pp. 587-592
    • Silverman, M.D.1    Tumuluri, R.J.2    Davis, M.3    Lopez, G.4    Rosenbaum, J.T.5    Lelkes, P.I.6
  • 30
    • 0036124199 scopus 로고    scopus 로고
    • Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells
    • DOI 10.1016/S0021-9150(01)00670-0, PII S0021915001006700
    • T Koga K Claycombe M Meydani 2002 Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells Atherosclerosis 161 365 374 11888519 10.1016/S0021-9150(01)00670-0 1:CAS:528:DC%2BD38XhvVWksbg%3D (Pubitemid 34219189)
    • (2002) Atherosclerosis , vol.161 , Issue.2 , pp. 365-374
    • Koga, T.1    Claycombe, K.2    Meydani, M.3
  • 31
    • 0027755295 scopus 로고
    • Effects of homocysteine and related compounds on prostacyclin production by cultured human vascular endothelial cells
    • J Wang NP Dudman DE Wilcken 1993 Effect of homocysteine and related compounds on prostacyclin production by cultured human vascular endothelial cells Thromb Haemost 70 1047 1052 8165599 1:CAS:528:DyaK2cXis1Ohurw%3D (Pubitemid 24008823)
    • (1993) Thrombosis and Haemostasis , vol.70 , Issue.6 , pp. 1047-1052
    • Wang, J.1    Dudman, N.P.B.2    Wilcken, D.E.L.3
  • 32
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium- derived relaxing factor and related oxides of nitrogen
    • JS Stamler JA Osborne O Jaraki LE Rabbani M Mullins D Singel J Loscalzo 1993 Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen J Clin Invest 91 308 318 8380812 10.1172/JCI116187 1:CAS:528:DyaK3sXhsVCrsbw%3D (Pubitemid 23037286)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.1 , pp. 308-318
    • Stamler, J.S.1    Osborne, J.A.2    Jaraki, O.3    Rabbani, L.E.4    Mullins, M.5    Singel, D.6    Loscalzo, J.7
  • 33
    • 0036963414 scopus 로고    scopus 로고
    • Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia
    • DOI 10.1191/1358863x02vm428ra
    • N Weiss C Keller U Hoffmann J Loscalzo 2002 Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia Vasc Med 7 227 239 12553746 10.1191/1358863x02vm428ra (Pubitemid 36104324)
    • (2002) Vascular Medicine , vol.7 , Issue.3 , pp. 227-239
    • Weiss, N.1    Keller, C.2    Hoffmann, U.3    Loscalzo, J.4
  • 34
    • 0022472013 scopus 로고
    • Activation of endogenous Factor V by a homocysteine-induced vascular endothelial cell activator
    • GM Rodgers WH Kane 1986 Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator J Clin Invest 77 1909 1916 3519683 10.1172/JCI112519 1:CAS:528:DyaL28XksFyqu78%3D (Pubitemid 16062647)
    • (1986) Journal of Clinical Investigation , vol.77 , Issue.6 , pp. 1909-1916
    • Rodgers, G.M.1    Kane, W.H.2
  • 35
    • 0034910719 scopus 로고    scopus 로고
    • Induction of oxidative stress by homocyst(e)ine impairs endothelial function
    • DOI 10.1002/jcb.1175
    • VS Mujumdar GM Aru SC Tyagi 2001 Induction of oxidative stress by homocysteine impairs endothelial function J Cell Biochem 82 491 500 11500925 10.1002/jcb.1175 1:CAS:528:DC%2BD3MXlslOitb8%3D (Pubitemid 32729412)
    • (2001) Journal of Cellular Biochemistry , vol.82 , Issue.3 , pp. 491-500
    • Mujumdar, V.S.1    Aru, G.M.2    Tyagi, S.C.3
  • 36
    • 0036912033 scopus 로고    scopus 로고
    • +-ATpase activity in hippocampus of rats subjected to acute administration of homocysteine is prevented by vitamins E and C treatment
    • DOI 10.1023/A:1021647329937
    • +-ATPase activity in hippocampus of rats subjected to acute administration of homocysteine is prevented by vitamins E and C treatment Neurochem Res 27 1685 1689 12515323 10.1023/A:1021647329937 1:CAS:528:DC%2BD38XpsFCju78%3D (Pubitemid 36020123)
    • (2002) Neurochemical Research , vol.27 , Issue.12 , pp. 1685-1689
    • Wyse, A.T.S.1    Zugno, A.I.2    Streck, E.L.3    Matte, C.4    Calcagnotto, T.5    Wannmacher, C.M.D.6    Wajner, M.7
  • 37
    • 2942571999 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein C activation by thrombogenic homocysteine
    • SR Lenz JE Sadler 1990 Inhibition of thrombomodulin surface expression and protein C activation by thrombogenic homocysteine Blood 88 1900 1904
    • (1990) Blood , vol.88 , pp. 1900-1904
    • Lenz, S.R.1    Sadler, J.E.2
  • 38
    • 37549032787 scopus 로고    scopus 로고
    • Homocysteine activates platelets in vitro
    • 18160593 10.1177/1076029607308390 1:CAS:528:DC%2BD1cXht12lsrc%3D
    • IV Mohan IA Jagroop DP Mikhailidis GP Stansby 2008 Homocysteine activates platelets in vitro Clin Appl Thromb Hemost 14 8 18 18160593 10.1177/1076029607308390 1:CAS:528:DC%2BD1cXht12lsrc%3D
    • (2008) Clin Appl Thromb Hemost , vol.14 , pp. 8-18
    • Mohan, I.V.1    Jagroop, I.A.2    Mikhailidis, D.P.3    Stansby, G.P.4
  • 41
    • 23244444302 scopus 로고    scopus 로고
    • Folate deficiency-induced hyperhomocysteinemia attenuates, and folic acid supplementation restores, the functional activities of rat coagulation factors XII, X, and II
    • LS Ebbesen J Ingerslev 2005 Folate deficiency-induced hyperhomocysteinemia attenuates, and folic acid supplementation restores, the functional activities of rat coagulation factors XII, X, and II J Nutr 135 1836 1840 16046705 1:CAS:528:DC%2BD2MXnvVSmtLs%3D (Pubitemid 41099738)
    • (2005) Journal of Nutrition , vol.135 , Issue.8 , pp. 1836-1840
    • Ebbesen, L.S.1    Ingerslev, J.2
  • 42
    • 0028814316 scopus 로고
    • Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis
    • 7823669 10.1016/S0140-6736(95)90166-3 1:STN:280:DyaK2M7isVShsw%3D%3D
    • T Koster AD Blann E Briet JP Vandenbroucke FR Rosendaal 1995 Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis Lancet 345 152 155 7823669 10.1016/S0140-6736(95)90166-3 1:STN:280:DyaK2M7isVShsw%3D%3D
    • (1995) Lancet , vol.345 , pp. 152-155
    • Koster, T.1    Blann, A.D.2    Briet, E.3    Vandenbroucke, J.P.4    Rosendaal, F.R.5
  • 43
    • 0033965871 scopus 로고    scopus 로고
    • Elevation of FVIII:C in venous thromboembolism is persistent and independent of the acute phase response
    • J O'Donnell AD Mumford RA Manning M Laffan 2000 Elevation of FVIII: C in venous thromboembolism is persistent and independent of the acute phase response Thromb Haemost 83 10 13 1:CAS:528:DC%2BD3cXktlOhsA%3D%3D (Pubitemid 30045468)
    • (2000) Thrombosis and Haemostasis , vol.83 , Issue.1 , pp. 10-13
    • O'Donnell, J.1    Mumford, A.D.2    Manning, R.A.3    Laffan, M.4
  • 44
    • 0036776063 scopus 로고    scopus 로고
    • In patients with deep-vein thrombosis elevated levels of factor VIII correlate only with von Willebrand factor but not other endothelial cell-derived coagulation and fibrinolysis proteins
    • DOI 10.1097/00001721-200210000-00001
    • T Bombeli M Jutzi E De Conno B Seifert J Fehr 2002 In patients with deep-vein thrombosis elevated levels of factor VIII correlate only with von Willebrand factor but not other endothelial cell-derived coagulation and fibrinolysis proteins Blood Coagul Fibrinolysis 13 577 581 12439142 10.1097/00001721-200210000-00001 1:CAS:528:DC%2BD38Xosl2gs7Y%3D (Pubitemid 35253352)
    • (2002) Blood Coagulation and Fibrinolysis , vol.13 , Issue.7 , pp. 577-581
    • Bombeli, T.1    Jutzi, M.2    De Conno, E.3    Seifert, B.4    Fehr, J.5
  • 45
    • 37049023661 scopus 로고    scopus 로고
    • The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels
    • DOI 10.3324/haematol.11611
    • WM Lijfering NJ Veeger JL Brouwer J van der Meer 2007 The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels Haematologica 92 1703 1706 18055997 10.3324/haematol.11611 1:CAS:528:DC%2BD1cXitVahsA%3D%3D (Pubitemid 350248253)
    • (2007) Haematologica , vol.92 , Issue.12 , pp. 1703-1706
    • Lijfering, W.M.1    Veeger, N.J.G.M.2    Brouwer, J.-L.P.3    Van Der Meer, J.4
  • 47
    • 0000333461 scopus 로고
    • A study of the coagulation defect in hemophilia and jaundice
    • 10.1097/00000441-193510000-00009
    • AJ Quick M Stanley-Brown FW Bancroft 1935 A study of the coagulation defect in hemophilia and jaundice Am J Med Sci 190 501 511 10.1097/00000441- 193510000-00009
    • (1935) Am J Med Sci , vol.190 , pp. 501-511
    • Quick, A.J.1    Stanley-Brown, M.2    Bancroft, F.W.3
  • 48
    • 72949143661 scopus 로고
    • The partial thromboplastin time with kaolin
    • 13738153 1:STN:280:DyaF3c%2Flslyhsw%3D%3D
    • RR Proctor SI Rapaport 1961 The partial thromboplastin time with kaolin Am J Clin Pathol 36 212 219 13738153 1:STN:280:DyaF3c%2Flslyhsw%3D%3D
    • (1961) Am J Clin Pathol , vol.36 , pp. 212-219
    • Proctor, R.R.1    Rapaport, S.I.2
  • 49
    • 33646774995 scopus 로고    scopus 로고
    • Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes
    • 16651872 10.1097/01.mbc.0000224849.19754.85 1:CAS:528: DC%2BD28XktVWhtbY%3D
    • LS Ebbesen SH Olesen M Kruhoffer J Ingerslev TF Orntoff 2006 Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes Blood Coagul Fibrinolysis 17 293 301 16651872 10.1097/01.mbc.0000224849.19754.85 1:CAS:528:DC%2BD28XktVWhtbY%3D
    • (2006) Blood Coagul Fibrinolysis , vol.17 , pp. 293-301
    • Ebbesen, L.S.1    Olesen, S.H.2    Kruhoffer, M.3    Ingerslev, J.4    Orntoff, T.F.5
  • 50
    • 0141450396 scopus 로고    scopus 로고
    • Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: Implications for the mechanism of thrombosis in hyperhomocysteinemia
    • 12871504 10.1046/j.1538-7836.2003.00053.x 1:CAS:528:DC%2BD2cXktFemsro%3D
    • DL Sauls AS Wolberg M Hoffman 2003 Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia J Thromb Haemost 1 300 306 12871504 10.1046/j.1538-7836.2003.00053.x 1:CAS:528:DC%2BD2cXktFemsro%3D
    • (2003) J Thromb Haemost , vol.1 , pp. 300-306
    • Sauls, D.L.1    Wolberg, A.S.2    Hoffman, M.3
  • 51
    • 1542267394 scopus 로고    scopus 로고
    • Factor XII deficiency: A thrombophilic risk factor for retinal vein occlusion
    • DOI 10.1016/j.ajo.2003.10.024, PII S0002939403012856
    • C Kuhli I Scharrer F Koch C Ohrloff LO Hattenbach 2004 Factor XII deficiency: a thrombophilic risk factor for retinal vein occlusion Am J Ophthalmol 137 459 464 15013868 10.1016/j.ajo.2003.10.024 1:CAS:528: DC%2BD2cXhvVygsb0%3D (Pubitemid 38328636)
    • (2004) American Journal of Ophthalmology , vol.137 , Issue.3 , pp. 459-464
    • Kuhli, C.1    Scharrer, I.2    Koch, F.3    Ohrloff, C.4    Hattenbach, L.-O.5
  • 54
    • 0028057277 scopus 로고
    • Thrombus formation and platelet-vessel wall interaction in the nephrotic syndrome under flow conditions
    • JJ Zwaginga HA Koomans JJ Sixma TJ Rabelink 1994 Thrombus formation and platelet-vessel wall interaction in the nephrotic syndrome under flow conditions J Clin Invest 93 204 211 8282789 10.1172/JCI116947 1:STN:280: DyaK2c7htVehtA%3D%3D (Pubitemid 24030838)
    • (1994) Journal of Clinical Investigation , vol.93 , Issue.1 , pp. 204-211
    • Zwaginga, J.J.1    Koomans, H.A.2    Sixma, J.J.3    Rabelink, T.J.4
  • 55
    • 0033932166 scopus 로고    scopus 로고
    • Oil fly ash-induced elevation of plasma fibrinogen levels in rats
    • SY Gardner JR Lehmann DL Costa 2000 Oil fly ash-induced elevation of plasma fibrinogen levels in rats Toxicol Sci 56 175 180 10869466 10.1093/toxsci/56.1.175 1:CAS:528:DC%2BD3cXkslKmsbw%3D (Pubitemid 30441477)
    • (2000) Toxicological Sciences , vol.56 , Issue.1 , pp. 175-180
    • Gardner, S.Y.1    Lehmann, J.R.2    Costa, D.L.3
  • 56
    • 77954088570 scopus 로고    scopus 로고
    • Incresed inflammatory markers in brain and blood of rats subjected to acute homocysteine administration
    • 20424906 10.1007/s11011-010-9188-8
    • AA da Cunha AG Ferreira AT Wyse 2010 Incresed inflammatory markers in brain and blood of rats subjected to acute homocysteine administration Metab Brain Dis 25 199 206 20424906 10.1007/s11011-010-9188-8
    • (2010) Metab Brain Dis , vol.25 , pp. 199-206
    • Da Cunha, A.A.1    Ferreira, A.G.2    Wyse, A.T.3
  • 57
    • 72649092774 scopus 로고    scopus 로고
    • Mechanism of action of homocysteine and its thiolactone in hemostasis system
    • 19093716 1:CAS:528:DC%2BD1MXhsFOmtL%2FO
    • K Karolczak B Olas 2009 Mechanism of action of homocysteine and its thiolactone in hemostasis system Physiol Res 58 623 633 19093716 1:CAS:528:DC%2BD1MXhsFOmtL%2FO
    • (2009) Physiol Res , vol.58 , pp. 623-633
    • Karolczak, K.1    Olas, B.2
  • 59
    • 0141925073 scopus 로고    scopus 로고
    • Nitric oxide in atherosclerosis
    • 12370036 10.2174/1389557023405666 1:CAS:528:DC%2BD38Xos1Cqsrw%3D
    • EA Rekka MC Chrysselis 2002 Nitric oxide in atherosclerosis Mini Rev Med Chem 2 585 593 12370036 10.2174/1389557023405666 1:CAS:528:DC%2BD38Xos1Cqsrw%3D
    • (2002) Mini Rev Med Chem , vol.2 , pp. 585-593
    • Rekka, E.A.1    Chrysselis, M.C.2
  • 60
    • 0030820780 scopus 로고    scopus 로고
    • Stimulation of endothelial nitric oxide production by homocyst(e)ine
    • DOI 10.1016/S0021-9150(97)00090-7, PII S0021915097000907
    • GR Upchurch Jr GN Welch AJ Fabian A Pigazzi JF Keaney Jr J Loscalzo 1997 Stimulation of endothelial nitric oxide production by homocysteine Atherosclerosis 132 177 185 9242963 10.1016/S0021-9150(97)00090-7 1:CAS:528:DyaK2sXkvFOgsrc%3D (Pubitemid 27311009)
    • (1997) Atherosclerosis , vol.132 , Issue.2 , pp. 177-185
    • Upchurch Jr., G.R.1    Welch, G.N.2    Fabian, A.J.3    Pigazzi, A.4    Keaney Jr., J.F.5    Loscalzo, J.6
  • 61
    • 0029664555 scopus 로고    scopus 로고
    • Homocysteine antagonism of nitric oxide-related cytostasis in Salmonella typhimurium
    • 8602531 10.1126/science.272.5260.414
    • MA de Groote T Testerman Y Xu G Stauffer FC Fang 1996 Homocysteine antagonism of nitric oxide-related cytostasis in Salmonella typhimurium Science 272 414 417 8602531 10.1126/science.272.5260.414
    • (1996) Science , vol.272 , pp. 414-417
    • De Groote, M.A.1    Testerman, T.2    Xu, Y.3    Stauffer, G.4    Fang, F.C.5
  • 62
    • 0042666891 scopus 로고    scopus 로고
    • Effects of homocysteine on L-arginine transport and nitric oxide formation in human platelets
    • DOI 10.1046/j.1365-2362.2003.01203.x
    • G Leoncini R Pascale MG Signorello 2003 Effects of homocysteine on l-arginine transport and nitric levels formation in human platelets Eur J Clin Investig 33 713 719 10.1046/j.1365-2362.2003.01203.x 1:CAS:528: DC%2BD3sXmsl2rtrc%3D (Pubitemid 36918635)
    • (2003) European Journal of Clinical Investigation , vol.33 , Issue.8 , pp. 713-719
    • Leoncini, G.1    Pascale, R.2    Signorello, M.G.3
  • 64
    • 0019313372 scopus 로고
    • Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite. Possible involvement of S-nitrosothiols
    • LJ Ignarro CA Gruetter 1980 Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite: possible involvement of S-nitrosothiols Biochim Biophys Acta 631 221 231 6105889 10.1016/0304-4165(80)90297-4 1:CAS:528:DyaL3cXlvVWktbc%3D (Pubitemid 10018147)
    • (1980) Biochimica et Biophysica Acta , vol.631 , Issue.2 , pp. 221-231
    • Ignarro, L.J.1    Gruetter, C.A.2
  • 65
    • 0030783147 scopus 로고    scopus 로고
    • Homocysteine as a modulator of platelet-derived growth factor action in vascular smooth muscle cells: A possible role for hydrogen peroxide
    • DOI 10.1038/sj.bjp.0701391
    • E Nishio Y Watanabe 1997 Homocysteine as a modulator of platelet-derived growth factor action in vascular smooth muscle cells: a possible role for hydrogen peroxide Br J Pharmacol 122 269 274 9313935 10.1038/sj.bjp.0701391 1:CAS:528:DyaK2sXmtlymsr4%3D (Pubitemid 27397198)
    • (1997) British Journal of Pharmacology , vol.122 , Issue.2 , pp. 269-274
    • Nishio, E.1    Watanabe, Y.2
  • 66
    • 0031935068 scopus 로고    scopus 로고
    • Homocystine redox receptor and regulation of extracellular matrix components in vascular cells
    • 9486129 1:CAS:528:DyaK1cXis1yqsLY%3D
    • SC Tyagi 1998 Homocystine redox receptor and regulation of extracellular matrix components in vascular cells Am J Physiol 274 C396 C405 9486129 1:CAS:528:DyaK1cXis1yqsLY%3D
    • (1998) Am J Physiol , vol.274
    • Tyagi, S.C.1
  • 68
    • 0002888991 scopus 로고
    • Superoxide mediated oxidation of low-density lipoproteins by thiols
    • P.A. Gerutti J.M. Gerutti I. McCord I. Fridovich (eds). Alan R. Liss New York
    • Heinecke JW (1988) Superoxide mediated oxidation of low-density lipoproteins by thiols. In: Gerutti PA, Gerutti JM, McCord I, Fridovich I (eds) Oxy-radicals in molecular biology and pathology. Alan R. Liss, New York, pp 433-457
    • (1988) Oxy-radicals in Molecular Biology and Pathology , pp. 433-457
    • Heinecke, J.W.1
  • 69
    • 67349187705 scopus 로고    scopus 로고
    • Homocysteine induces oxidative stress, inflammatory infiltration, fibrosis and reduces glycogen/glycoprotein content in liver of rats
    • 19460627 10.1016/j.ijdevneu.2009.03.005
    • C Matté FM Stefanello V Mackedanz CD Pederzolli ML Lamers CS Dutra-Filho MF dos Santos AT Wyse 2009 Homocysteine induces oxidative stress, inflammatory infiltration, fibrosis and reduces glycogen/glycoprotein content in liver of rats Int J Dev Neurosci 27 337 344 19460627 10.1016/j.ijdevneu.2009. 03.005
    • (2009) Int J Dev Neurosci , vol.27 , pp. 337-344
    • Matté, C.1    Stefanello, F.M.2    MacKedanz, V.3    Pederzolli, C.D.4    Lamers, M.L.5    Dutra-Filho, C.S.6    Dos Santos, M.F.7    Wyse, A.T.8
  • 70
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocyst(e)inemia
    • 8690803 10.1172/JCI118776 1:CAS:528:DyaK28XktFWgsL4%3D
    • J Loscalzo 1996 The oxidant stress of hyperhomocyst(e)inemia J Clin Invest 98 5 7 8690803 10.1172/JCI118776 1:CAS:528:DyaK28XktFWgsL4%3D
    • (1996) J Clin Invest , vol.98 , pp. 5-7
    • Loscalzo, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.