-
1
-
-
33847159163
-
Pollution atmosphérique et maladies respiratoires allergiques
-
Bonay M, Aubier M. Pollution atmosphérique et maladies respiratoires allergiques. Med Sci (Paris) 2007;23:187-92. (Pubitemid 46293865)
-
(2007)
Medecine/Sciences
, vol.23
, Issue.2
, pp. 187-192
-
-
Bonay, M.1
Aubier, M.2
-
2
-
-
64849113028
-
Role of catalase in monocytic differentiation of U937 cells by TPA: Hydrogen peroxide as a second messenger
-
Yamamoto T, Sakaguchi N, Hachiya M, et al. Role of catalase in monocytic differentiation of U937 cells by TPA: hydrogen peroxide as a second messenger. Leukemia 2009;23:761-9.
-
(2009)
Leukemia
, vol.23
, pp. 761-769
-
-
Yamamoto, T.1
Sakaguchi, N.2
Hachiya, M.3
-
3
-
-
77956624172
-
Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract
-
Rangasamy T, Williams MA, Bauer S, et al. Nuclear erythroid 2 p45-related factor 2 inhibits the maturation of murine dendritic cells by ragweed extract. Am J Respir Cell Mot Biol 2010;43:276-85.
-
(2010)
Am J Respir Cell Mot Biol
, vol.43
, pp. 276-285
-
-
Rangasamy, T.1
Williams, M.A.2
Bauer, S.3
-
4
-
-
37549071817
-
Oxidative stress and antioxidants in the pathogenesis of pulmonary fibrosis: A potential role for Nrf2
-
Walters DM, Cho HY, Kleeberger SR. Oxidative stress and antioxidants in the pathogenesis of pulmonary fibrosis: a potential role for Nrf2. Antioxid Redox Signal 2008;10:321-32.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 321-332
-
-
Walters, D.M.1
Cho, H.Y.2
Kleeberger, S.R.3
-
6
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
DOI 10.1016/j.biocel.2006.07.001, PII S1357272506002196
-
Valko M, Leibfntz D, Moncol J, et al. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44-84. (Pubitemid 44566469)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Telser, J.6
-
7
-
-
77957021509
-
Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited
-
Leonarduzzi G, Sottero B, Poli G. Targeting tissue oxidative damage by means of cell signaling modulators: the antioxidant concept revisited. Pharmacol Ther 2010;128:336-74.
-
(2010)
Pharmacol Ther
, vol.128
, pp. 336-374
-
-
Leonarduzzi, G.1
Sottero, B.2
Poli, G.3
-
8
-
-
77953012548
-
Stress-activated cap'n'collar transcription factors in aging and human disease
-
Sykiotis GP, Bohmann D. Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 2010;3. re3.
-
(2010)
Sci Signal
, vol.3
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
9
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keapl-Nrf2-ARE pathway
-
Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keapl-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 2007;47:89-116.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
10
-
-
34347225583
-
NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20S proteasomal degradation leading to stabilization and activation of p53
-
DOI 10.1158/0008-5472.CAN-07-0323
-
Gong X, Kole L, Iskander K, Jaiswal AK. NRH: quinone oxidoreductase 2 and NAD (P) H: quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53. Cancer Res 2007;67:5380-8. (Pubitemid 46997278)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5380-5388
-
-
Gong, X.1
Kole, L.2
Iskander, K.3
Jaiswal, A.K.4
-
12
-
-
77957237159
-
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChlP-Seq profiling and network analysis
-
Malhotra D, Portales-Casamar E, Singh A, et al. Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChlP-Seq profiling and network analysis. Nucleic Acids Res 2010;38:5718-34.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5718-5734
-
-
Malhotra, D.1
Portales-Casamar, E.2
Singh, A.3
-
13
-
-
34447556991
-
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
-
DOI 10.1152/physrev.00048.2006
-
Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev 2007;87:1047-82. (Pubitemid 47084676)
-
(2007)
Physiological Reviews
, vol.87
, Issue.3
, pp. 1047-1082
-
-
Yoshida, T.1
Tuder, R.M.2
-
14
-
-
70149110900
-
Smoking-dependent reprogramming of alveolar macrophage polarization: Implication for pathogenesis of chronic obstructive pulmonary disease
-
Shaykhiev R, Krause A, Salit J, et al. Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J Immunol 2009;183:2867-83.
-
(2009)
J Immunol
, vol.183
, pp. 2867-2883
-
-
Shaykhiev, R.1
Krause, A.2
Salit, J.3
-
15
-
-
66149093072
-
The pathology of chronic obstructive pulmonary disease
-
Hogg JC, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009;4:435-59.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 435-459
-
-
Hogg, J.C.1
Timens, W.2
-
16
-
-
53649099660
-
Altered Nrf2/Keapl-Bachl equilibrium in pulmonary emphysema
-
Goven D, Boutten A, Lecon-Malas V, et al. Altered Nrf2/Keapl-Bachl equilibrium in pulmonary emphysema. Thorax 2008;63:916-924.
-
(2008)
Thorax
, vol.63
, pp. 916-924
-
-
Goven, D.1
Boutten, A.2
Lecon-Malas, V.3
-
17
-
-
70350316759
-
Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bachl expression in human macrophages: Roles of the MAP kinases ERK (l/2) and JNK
-
Goven D, Boutten A, Lecon-Malas V, et al. Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bachl expression in human macrophages: roles of the MAP kinases ERK (l/2) and JNK. FCBS Lett 2009;583:3508-18.
-
(2009)
FCBS Lett
, vol.583
, pp. 3508-3518
-
-
Goven, D.1
Boutten, A.2
Lecon-Malas, V.3
-
18
-
-
51849129227
-
Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1
-
Malhotra D, Thimmulappa R, Navas-Acien A, et al. Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Am J Respir Crit Care Med 2008;178:592-604.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 592-604
-
-
Malhotra, D.1
Thimmulappa, R.2
Navas-Acien, A.3
-
19
-
-
72549115279
-
Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity
-
Malhotra D, Thimmulappa R, Vij N, et al. Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med 2009;180:1196-207.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 1196-1207
-
-
Malhotra, D.1
Thimmulappa, R.2
Vij, N.3
-
20
-
-
77149161203
-
Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population
-
Siedlinski M, Postma DS, Boer JM, et al. Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population. Respir Res 2009;10:73.
-
(2009)
Respir Res
, vol.10
, pp. 73
-
-
Siedlinski, M.1
Postma, D.S.2
Boer, J.M.3
-
21
-
-
70449440734
-
New mechanisms of pulmonary fibrosis
-
Strieter RM, Mehrad B. New mechanisms of pulmonary fibrosis. Chest 2009;136:1364-70.
-
(2009)
Chest
, vol.136
, pp. 1364-1370
-
-
Strieter, R.M.1
Mehrad, B.2
-
22
-
-
69949114515
-
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
-
Hecker L, Vittal R, Jones T, et al. NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med 2009;15:1077-81.
-
(2009)
Nat Med
, vol.15
, pp. 1077-1081
-
-
Hecker, L.1
Vittal, R.2
Jones, T.3
-
23
-
-
0036318224
-
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
-
DOI 10.1128/MCB.22.15.5492-5505.2002
-
Braun S, Hanselmann C, Gassmann MG, et al. Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol 2002;22:5492-505. (Pubitemid 34755759)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.15
, pp. 5492-5505
-
-
Braun, S.1
Hanselmann, C.2
Gassmann, M.G.3
Keller, U.A.4
Born-Berclaz, C.5
Chan, K.6
Kan, Y.W.7
Werner, S.8
-
24
-
-
11344292584
-
Smad3-ATF3 signaling mediates TGF-β suppression of genes encoding Phase II detoxifying proteins
-
DOI 10.1016/j.freeradbiomed.2004.10.033, PII S0891584904008822
-
Bakin AV, Stourman NV, Sekhar KR, et al. Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins. Free Radic Biol Med 2005;38:375-87. (Pubitemid 40075579)
-
(2005)
Free Radical Biology and Medicine
, vol.38
, Issue.3
, pp. 375-387
-
-
Bakin, A.V.1
Stourman, N.V.2
Sekhar, K.R.3
Rinehart, C.4
Yan, X.5
Meredith, M.J.6
Arteaga, C.L.7
Freeman, M.L.8
-
25
-
-
77955960441
-
Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia
-
Mazur W, Lindholm P, Vuorinen K, et al. Cell-specific elevation of NRF2 and sulfiredoxin-1 as markers of oxidative stress in the lungs of idiopathic pulmonary fibrosis and non-specific interstitial pneumonia. Apmis 2010;118:703-12.
-
(2010)
Apmis
, vol.118
, pp. 703-712
-
-
Mazur, W.1
Lindholm, P.2
Vuorinen, K.3
-
26
-
-
83455220718
-
Modulation of fibroblast phenotype in idiopathic pulmonary fibrosis: Role of Nrf2
-
Artaud-Macari E, Goven D, Brayer S, et al. Modulation of fibroblast phenotype in idiopathic pulmonary fibrosis: role of Nrf2. Am J Respir Erit Care Med 2011;183: A5989.
-
(2011)
Am J Respir Erit Care Med
, vol.183
-
-
Artaud-Macari, E.1
Goven, D.2
Brayer, S.3
-
27
-
-
34347392512
-
Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury
-
DOI 10.1096/fj.06-7759com
-
Marzec JM, Christie JD, Reddy SP, et al. Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. Faseb J 2007;21:2237-46. (Pubitemid 47026458)
-
(2007)
FASEB Journal
, vol.21
, Issue.9
, pp. 2237-2246
-
-
Marzec, J.M.1
Christie, J.D.2
Reddy, S.P.3
Jedlicka, A.E.4
Vuong, H.5
Lanken, P.N.6
Aplenc, R.7
Yamamoto, T.8
Yamamoto, M.9
Cho, H.-Y.10
Kleeberger, S.R.11
-
28
-
-
77952228191
-
Toluene diisocyanate (TDl) regulates haem oxygenase-1/femtin expression: Implications for toluene diisocyanateinduced asthma
-
Kim SH, Choi GS, ye YM, et al. Toluene diisocyanate (TDl) regulates haem oxygenase-1/femtin expression: implications for toluene diisocyanateinduced asthma. Clin Cxp Immunol 2010;160:489-97.
-
(2010)
Clin Cxp Immunol
, vol.160
, pp. 489-497
-
-
Kim, S.H.1
Choi, G.S.2
Ye, Y.M.3
-
29
-
-
72449174784
-
The tnterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease
-
Nichols DP, Ziady AG, Shank SL, et al. The tnterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease. Am J Physiol Lung Cell Mol Physiol 2009;297: L828-36.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Nichols, D.P.1
Ziady, A.G.2
Shank, S.L.3
-
30
-
-
77954068742
-
NF-E2-related factor 2, a key inducer of antioxidant defenses, negatively regulates the CFTR transcription
-
Rene C, Lopez E, Claustres M, et al. NF-E2-related factor 2, a key inducer of antioxidant defenses, negatively regulates the CFTR transcription. Cell Mol Life Sci 2010;67:2297-309.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 2297-2309
-
-
Rene, C.1
Lopez, E.2
Claustres, M.3
-
31
-
-
40449107193
-
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth
-
DOI 10.1158/0008-5472.CAN-07-5003
-
Ohta T, lijima K, Miyamoto M, et al. Loss of Keapl function activates Nrf 2 and provides advantages for lung cancer cell growth. Cancer Res 2008;68:1303-9. (Pubitemid 351346836)
-
(2008)
Cancer Research
, vol.68
, Issue.5
, pp. 1303-1309
-
-
Ohta, T.1
Iijima, K.2
Miyamoto, M.3
Nakahara, I.4
Tanaka, H.5
Ohtsuji, M.6
Suzuki, T.7
Kobayashi, A.8
Yokota, J.9
Sakiyama, T.10
Shibata, T.11
Yamamoto, M.12
Hirohashi, S.13
-
33
-
-
79960273488
-
NRF2 targeting: A promising therapeutic strategy in chronic obstructive pulmonary disease
-
Boutten A, Goven D, Artaud-Macari E, et al. NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease. Trends Mol Med 2011;17:363-71.
-
(2011)
Trends Mol Med
, vol.17
, pp. 363-371
-
-
Boutten, A.1
Goven, D.2
Artaud-Macari, E.3
-
34
-
-
33847749502
-
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer
-
DOI 10.1038/nm1556, PII NM1556
-
Spira A, Beane JE, Shah V, et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med 2007;13:361-6. (Pubitemid 46376687)
-
(2007)
Nature Medicine
, vol.13
, Issue.3
, pp. 361-366
-
-
Spira, A.1
Beane, J.E.2
Shah, V.3
Steiling, K.4
Liu, G.5
Schembri, F.6
Gilman, S.7
Dumas, Y.-M.8
Calner, P.9
Sebastiani, P.10
Sridhar, S.11
Beamis, J.12
Lamb, C.13
Anderson, T.14
Gerry, N.15
Keane, J.16
Lenburg, M.E.17
Brody, J.S.18
-
35
-
-
34250901586
-
Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice
-
DOI 10.1158/0008-5472.CAN-06-3355
-
Aoki Y, Hashimoto AH, Amanuma K, et al. Enhanced spontaneous and benzo (a) pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice. Cancer Res 2007;67:5643-8. (Pubitemid 46984995)
-
(2007)
Cancer Research
, vol.67
, Issue.12
, pp. 5643-5648
-
-
Aoki, Y.1
Hashimoto, A.H.2
Amanuma, K.3
Matsumoto, M.4
Hiyoshi, K.5
Takano, H.6
Masumura, K.-I.7
Itoh, K.8
Nohmi, T.9
Yamamoto, M.10
-
36
-
-
79551646862
-
NRF2, cancer and calorie restriction
-
Martin-Montalvo A, Villalba JM, Novas P, de Cabo R. NRF2, cancer and calorie restriction. Oncogene 2010;30:505-20.
-
(2010)
Oncogene
, vol.30
, pp. 505-520
-
-
Martin-Montalvo, A.1
Villalba, J.M.2
Novas, P.3
De Cabo, R.4
-
37
-
-
51649130168
-
Cancer related mutations in NRF2 impair its recognition by Keopl-Cul3 E3 ligase and promote malignancy
-
Shibota T, Ohta T, Tong Kl, et al. Cancer related mutations in NRF2 impair its recognition by Keopl-Cul3 E3 ligase and promote malignancy. Proc Natl Acad Sci USA 2008;105:13568-73.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13568-13573
-
-
Shibota, T.1
Ohta, T.2
Kl, T.3
-
38
-
-
63549121490
-
NRF2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer
-
Hayes JD, McMahon M. NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. Trends Biochem Sci 2009;34:176-88.
-
(2009)
Trends Biochem Sci
, vol.34
, pp. 176-188
-
-
Hayes, J.D.1
McMahon, M.2
-
39
-
-
77951939611
-
Activation of apoptosis signalregulating kinase 1 is a key factor in paraquat-induced cell death: Modulation by the Nrf2/Trx axis
-
Niso-Santano M, Gonzalez-Polo RA, Bravo-San Pedro JM, et al. Activation of apoptosis signalregulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis. Free Radic Biol Med 2010;48:1370-81.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1370-1381
-
-
Niso-Santano, M.1
Gonzalez-Polo, R.A.2
Bravo-San Pedro, J.M.3
-
40
-
-
78649710411
-
The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/H01 pathway
-
Shah ZA, Li RC, Ahmad AS, et al. The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/H01 pathway. J Cereb Blood Flow Metab 2010;30:1951-61.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1951-1961
-
-
Shah, Z.A.1
Li, R.C.2
Ahmad, A.S.3
-
41
-
-
62249089498
-
Targeting the redox sensitive Nrf 2-Keapl defense pathway in cardiovascular disease, protection afforded by dietary isoflavones
-
Mann GE, Bonacasa B, Ishii T, Siow RC. Targeting the redox sensitive Nrf 2-Keapl defense pathway in cardiovascular disease, protection afforded by dietary isoflavones. Curr Opin Pharmacol 2009;9:139-45.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 139-145
-
-
Mann, G.E.1
Bonacasa, B.2
Ishii, T.3
Siow, R.C.4
-
42
-
-
43049117465
-
Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme
-
Yoon HY, Kang Nl, Lee HK, et al. Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. Biochem Pharmacol 2008;75:2214-23.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 2214-2223
-
-
Yoon, H.Y.1
Nl, K.2
Lee, H.K.3
-
43
-
-
67349170402
-
Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: Role of heme oxygenase-1
-
Hsu CL, Wu L, Tang GJ, et al. Ginkgo biloba extract confers protection from cigarette smoke extract-induced apoptosis in human lung endothelial cells: role of heme oxygenase-1. Pulm Pharmacol Ther 2009;22:286-96.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 286-296
-
-
Hsu, C.L.1
Wu, L.2
Tang, G.J.3
-
44
-
-
66749132810
-
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
-
Yang L, Calingasan Ny, Thomas B, et al. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. PLoS One 2009;4:e5757.
-
(2009)
PLoS One
, vol.4
-
-
Yang, L.1
Ny, C.2
Thomas, B.3
-
45
-
-
77954067261
-
Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes
-
Ichikawa T, Li J, Meyer CJ, et al. Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes. PLoS One 2009;4:e8391.
-
(2009)
PLoS One
, vol.4
-
-
Ichikawa, T.1
Li, J.2
Meyer, C.J.3
-
46
-
-
58549105575
-
Targeting Nrf 2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
-
Sussan TE, Rangasamy T, Blake DJ, et al. Targeting Nrf 2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proc Natl Acad Sci USA 2009;106:250-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 250-255
-
-
Sussan, T.E.1
Rangasamy, T.2
Blake, D.J.3
|