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Volumn 6, Issue 12, 2011, Pages

FSP27 promotes lipid droplet clustering and then fusion to regulate triglyceride accumulation

Author keywords

[No Author keywords available]

Indexed keywords

FAT DROPLET; FAT SPECIFIC PROTEIN 27; REGULATOR PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; AMINO ACID; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEIN;

EID: 83355173216     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028614     Document Type: Article
Times cited : (118)

References (48)
  • 1
    • 33644668609 scopus 로고    scopus 로고
    • Cell biology. Great balls of fat
    • Beckman M, (2006) Cell biology. Great balls of fat. Science 311: 1232-1234.
    • (2006) Science , vol.311 , pp. 1232-1234
    • Beckman, M.1
  • 2
    • 70449769682 scopus 로고    scopus 로고
    • Lipid droplets finally get a little R-E-S-P-E-C-T
    • Farese RV, Walther TC, (2009) Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139: 855-860.
    • (2009) Cell , vol.139 , pp. 855-860
    • Farese, R.V.1    Walther, T.C.2
  • 3
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
    • Brasaemle DL, (2007) Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res 48: 2547-2559.
    • (2007) J Lipid Res , vol.48 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 4
    • 40849145708 scopus 로고    scopus 로고
    • Lipid droplets in lipogenesis and lipolysis
    • Ducharme NA, Bickel PE, (2008) Lipid droplets in lipogenesis and lipolysis. Endocrinology 149: 942-949.
    • (2008) Endocrinology , vol.149 , pp. 942-949
    • Ducharme, N.A.1    Bickel, P.E.2
  • 5
    • 33749058310 scopus 로고    scopus 로고
    • A proposed model of fat packaging by exchangeable lipid droplet proteins
    • Wolins NE, Brasaemle DL, Bickel PE, (2006) A proposed model of fat packaging by exchangeable lipid droplet proteins. FEBS Lett 580: 5484-5491.
    • (2006) FEBS Lett , vol.580 , pp. 5484-5491
    • Wolins, N.E.1    Brasaemle, D.L.2    Bickel, P.E.3
  • 6
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: a unified view of a dynamic organelle
    • Martin S, Parton RG, (2006) Lipid droplets: a unified view of a dynamic organelle. Nat Rev Mol Cell Biol 7: 373-378.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 8
    • 77950607704 scopus 로고    scopus 로고
    • Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins
    • Kimmel AR, Brasaemle DL, McAndrews-Hill M, Sztalryd C, Londos C, (2010) Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. J Lipid Res 51: 468-471.
    • (2010) J Lipid Res , vol.51 , pp. 468-471
    • Kimmel, A.R.1    Brasaemle, D.L.2    McAndrews-Hill, M.3    Sztalryd, C.4    Londos, C.5
  • 9
    • 36348940037 scopus 로고    scopus 로고
    • Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage
    • Puri V, Konda S, Ranjit S, Aouadi M, Chawla A, et al. (2007) Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage. J Biol Chem 282: 34213-34218.
    • (2007) J Biol Chem , vol.282 , pp. 34213-34218
    • Puri, V.1    Konda, S.2    Ranjit, S.3    Aouadi, M.4    Chawla, A.5
  • 10
    • 44949130214 scopus 로고    scopus 로고
    • Fat-specific protein 27 regulates storage of triacylglycerol
    • Keller P, Petrie JT, De Rose P, Gerin I, Wright WS, et al. (2008) Fat-specific protein 27 regulates storage of triacylglycerol. J Biol Chem 283: 14355-14365.
    • (2008) J Biol Chem , vol.283 , pp. 14355-14365
    • Keller, P.1    Petrie, J.T.2    De Rose, P.3    Gerin, I.4    Wright, W.S.5
  • 11
    • 8744267532 scopus 로고    scopus 로고
    • Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
    • Brasaemle DL, Dolios G, Shapiro L, Wang R, (2004) Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J Biol Chem 279: 46835-46842.
    • (2004) J Biol Chem , vol.279 , pp. 46835-46842
    • Brasaemle, D.L.1    Dolios, G.2    Shapiro, L.3    Wang, R.4
  • 12
    • 41449098953 scopus 로고    scopus 로고
    • Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27
    • Matsusue K, Kusakabe T, Noguchi T, Takiguchi S, Suzuki T, et al. (2008) Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27. Cell Metab 7: 302-311.
    • (2008) Cell Metab , vol.7 , pp. 302-311
    • Matsusue, K.1    Kusakabe, T.2    Noguchi, T.3    Takiguchi, S.4    Suzuki, T.5
  • 13
    • 70450220107 scopus 로고    scopus 로고
    • Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC
    • Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, et al. (2009) Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med 1: 280-287.
    • (2009) EMBO Mol Med , vol.1 , pp. 280-287
    • Rubio-Cabezas, O.1    Puri, V.2    Murano, I.3    Saudek, V.4    Semple, R.K.5
  • 14
    • 48749103552 scopus 로고    scopus 로고
    • FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets
    • Nishino N, Tamori Y, Tateya S, Kawaguchi T, Shibakusa T, et al. (2008) FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. J Clin Invest 118: 2808-2821.
    • (2008) J Clin Invest , vol.118 , pp. 2808-2821
    • Nishino, N.1    Tamori, Y.2    Tateya, S.3    Kawaguchi, T.4    Shibakusa, T.5
  • 15
    • 72249118392 scopus 로고    scopus 로고
    • Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA
    • Liu K, Zhou S, Kim JY, Tillison K, Majors D, et al. (2009) Functional analysis of FSP27 protein regions for lipid droplet localization, caspase-dependent apoptosis, and dimerization with CIDEA. Am J Physiol Endocrinol Metab 297: E1395-1413.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Liu, K.1    Zhou, S.2    Kim, J.Y.3    Tillison, K.4    Majors, D.5
  • 16
    • 33845344737 scopus 로고    scopus 로고
    • 20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma
    • Fang X, Dillon JS, Hu S, Harmon SD, Yao J, et al. (2007) 20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma. Prostaglandins Other Lipid Mediat 82: 175-184.
    • (2007) Prostaglandins Other Lipid Mediat , vol.82 , pp. 175-184
    • Fang, X.1    Dillon, J.S.2    Hu, S.3    Harmon, S.D.4    Yao, J.5
  • 17
    • 0029745382 scopus 로고    scopus 로고
    • Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice
    • Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, et al. (1996) Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137: 4189-4195.
    • (1996) Endocrinology , vol.137 , pp. 4189-4195
    • Berger, J.1    Bailey, P.2    Biswas, C.3    Cullinan, C.A.4    Doebber, T.W.5
  • 18
    • 0033169058 scopus 로고    scopus 로고
    • An adipogenic cofactor bound by the differentiation domain of PPARgamma
    • Castillo G, Brun RP, Rosenfield JK, Hauser S, Park CW, et al. (1999) An adipogenic cofactor bound by the differentiation domain of PPARgamma. EMBO J 18: 3676-3687.
    • (1999) EMBO J , vol.18 , pp. 3676-3687
    • Castillo, G.1    Brun, R.P.2    Rosenfield, J.K.3    Hauser, S.4    Park, C.W.5
  • 19
    • 26944489689 scopus 로고    scopus 로고
    • Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
    • Gronke S, Mildner A, Fellert S, Tennagels N, Petry S, et al. (2005) Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab 1: 323-330.
    • (2005) Cell Metab , vol.1 , pp. 323-330
    • Gronke, S.1    Mildner, A.2    Fellert, S.3    Tennagels, N.4    Petry, S.5
  • 20
    • 33846991295 scopus 로고    scopus 로고
    • Differential localization of aquaporin-2 and glucose transporter 4 in polarized MDCK cells
    • Hasegawa T, Matsuzaki T, Tajika Y, Ablimit A, Suzuki T, et al. (2007) Differential localization of aquaporin-2 and glucose transporter 4 in polarized MDCK cells. Histochem Cell Biol 127: 233-241.
    • (2007) Histochem Cell Biol , vol.127 , pp. 233-241
    • Hasegawa, T.1    Matsuzaki, T.2    Tajika, Y.3    Ablimit, A.4    Suzuki, T.5
  • 21
    • 77957350902 scopus 로고    scopus 로고
    • PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B
    • Lu X, Murphy TC, Nanes MS, Hart CM, (2010) PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B. Am J Physiol Lung Cell Mol Physiol 299: L559-566.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299
    • Lu, X.1    Murphy, T.C.2    Nanes, M.S.3    Hart, C.M.4
  • 22
    • 0034071705 scopus 로고    scopus 로고
    • Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs
    • Martinez-Arca S, Lalioti VS, Sandoval IV, (2000) Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs. J Cell Sci 113 (Pt 10): 1705-1715.
    • (2000) J Cell Sci , vol.113 , Issue.PT 10 , pp. 1705-1715
    • Martinez-Arca, S.1    Lalioti, V.S.2    Sandoval, I.V.3
  • 23
    • 1542341626 scopus 로고    scopus 로고
    • Perilipin expression in human adipose tissues: effects of severe obesity, gender, and depot
    • Wang Y, Sullivan S, Trujillo M, Lee MJ, Schneider SH, et al. (2003) Perilipin expression in human adipose tissues: effects of severe obesity, gender, and depot. Obes Res 11: 930-936.
    • (2003) Obes Res , vol.11 , pp. 930-936
    • Wang, Y.1    Sullivan, S.2    Trujillo, M.3    Lee, M.J.4    Schneider, S.H.5
  • 25
    • 0030024112 scopus 로고    scopus 로고
    • CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter
    • Zhang DE, Hetherington CJ, Meyers S, Rhoades KL, Larson CJ, et al. (1996) CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol Cell Biol 16: 1231-1240.
    • (1996) Mol Cell Biol , vol.16 , pp. 1231-1240
    • Zhang, D.E.1    Hetherington, C.J.2    Meyers, S.3    Rhoades, K.L.4    Larson, C.J.5
  • 26
    • 8744297386 scopus 로고    scopus 로고
    • Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis
    • Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS, (2004) Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. J Biol Chem 279: 47066-47075.
    • (2004) J Biol Chem , vol.279 , pp. 47066-47075
    • Villena, J.A.1    Roy, S.2    Sarkadi-Nagy, E.3    Kim, K.H.4    Sul, H.S.5
  • 27
    • 33845517481 scopus 로고    scopus 로고
    • OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization
    • Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Croce MA, et al. (2006) OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes 55: 3418-3428.
    • (2006) Diabetes , vol.55 , pp. 3418-3428
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3    Tzekov, A.4    Croce, M.A.5
  • 28
    • 33646128723 scopus 로고    scopus 로고
    • Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
    • Lass A, Zimmermann R, Haemmerle G, Riederer M, Schoiswohl G, et al. (2006) Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab 3: 309-319.
    • (2006) Cell Metab , vol.3 , pp. 309-319
    • Lass, A.1    Zimmermann, R.2    Haemmerle, G.3    Riederer, M.4    Schoiswohl, G.5
  • 29
    • 79953160438 scopus 로고    scopus 로고
    • Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase
    • Granneman JG, Moore HP, Mottillo EP, Zhu Z, Zhou L, (2011) Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase. J Biol Chem 286: 5126-5135.
    • (2011) J Biol Chem , vol.286 , pp. 5126-5135
    • Granneman, J.G.1    Moore, H.P.2    Mottillo, E.P.3    Zhu, Z.4    Zhou, L.5
  • 30
    • 41649112075 scopus 로고    scopus 로고
    • Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death
    • Kim JY, Liu K, Zhou S, Tillison K, Wu Y, et al. (2008) Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death. Am J Physiol Endocrinol Metab 294: E654-667.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Kim, J.Y.1    Liu, K.2    Zhou, S.3    Tillison, K.4    Wu, Y.5
  • 31
    • 78751524862 scopus 로고    scopus 로고
    • Regulation of fat specific protein 27 by isoproterenol and TNF-alpha to control lipolysis in murine adipocytes
    • Ranjit S, Boutet E, Gandhi P, Prot M, Tamori Y, et al. (2011) Regulation of fat specific protein 27 by isoproterenol and TNF-alpha to control lipolysis in murine adipocytes. J Lipid Res 52: 221-236.
    • (2011) J Lipid Res , vol.52 , pp. 221-236
    • Ranjit, S.1    Boutet, E.2    Gandhi, P.3    Prot, M.4    Tamori, Y.5
  • 32
    • 78650065000 scopus 로고    scopus 로고
    • Identification of the lipid droplet targeting domain of the Cidea protein
    • Christianson JL, Boutet E, Puri V, Chawla A, Czech MP, (2010) Identification of the lipid droplet targeting domain of the Cidea protein. J Lipid Res 51: 3455-3462.
    • (2010) J Lipid Res , vol.51 , pp. 3455-3462
    • Christianson, J.L.1    Boutet, E.2    Puri, V.3    Chawla, A.4    Czech, M.P.5
  • 34
    • 48749104591 scopus 로고    scopus 로고
    • Lipid droplets: FSP27 knockout enhances their sizzle
    • Puri V, Czech MP, (2008) Lipid droplets: FSP27 knockout enhances their sizzle. J Clin Invest 118: 2693-2696.
    • (2008) J Clin Invest , vol.118 , pp. 2693-2696
    • Puri, V.1    Czech, M.P.2
  • 36
    • 32144432437 scopus 로고    scopus 로고
    • The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
    • Arnold K, Bordoli L, Kopp J, Schwede T, (2006) The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. Bioinformatics 22: 195-201.
    • (2006) Bioinformatics , vol.22 , pp. 195-201
    • Arnold, K.1    Bordoli, L.2    Kopp, J.3    Schwede, T.4
  • 37
    • 0037674997 scopus 로고    scopus 로고
    • Fixation methods for the study of lipid droplets by immunofluorescence microscopy
    • DiDonato D, Brasaemle DL, (2003) Fixation methods for the study of lipid droplets by immunofluorescence microscopy. J Histochem Cytochem 51: 773-780.
    • (2003) J Histochem Cytochem , vol.51 , pp. 773-780
    • DiDonato, D.1    Brasaemle, D.L.2
  • 38
    • 78650825607 scopus 로고    scopus 로고
    • Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens
    • Murphy S, Martin S, Parton RG, (2010) Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PLoS One 5: e15030.
    • (2010) PLoS One , vol.5
    • Murphy, S.1    Martin, S.2    Parton, R.G.3
  • 39
    • 35748972649 scopus 로고    scopus 로고
    • SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity
    • Bostrom P, Andersson L, Rutberg M, Perman J, Lidberg U, et al. (2007) SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity. Nat Cell Biol 9: 1286-1293.
    • (2007) Nat Cell Biol , vol.9 , pp. 1286-1293
    • Bostrom, P.1    Andersson, L.2    Rutberg, M.3    Perman, J.4    Lidberg, U.5
  • 40
    • 70350144713 scopus 로고    scopus 로고
    • The assembly of lipid droplets and its relation to cellular insulin sensitivity
    • Bostrom P, Andersson L, Li L, Perkins R, Hojlund K, et al. (2009) The assembly of lipid droplets and its relation to cellular insulin sensitivity. Biochem Soc Trans 37: 981-985.
    • (2009) Biochem Soc Trans , vol.37 , pp. 981-985
    • Bostrom, P.1    Andersson, L.2    Li, L.3    Perkins, R.4    Hojlund, K.5
  • 41
    • 77957278964 scopus 로고    scopus 로고
    • Cell death-inducing DFF45-like effector, a lipid droplet-associated protein, might be involved in the differentiation of human adipocytes
    • Li F, Gu Y, Dong W, Li H, Zhang L, et al. (2010) Cell death-inducing DFF45-like effector, a lipid droplet-associated protein, might be involved in the differentiation of human adipocytes. FEBS J 277: 4173-4183.
    • (2010) FEBS J , vol.277 , pp. 4173-4183
    • Li, F.1    Gu, Y.2    Dong, W.3    Li, H.4    Zhang, L.5
  • 42
    • 51449123610 scopus 로고    scopus 로고
    • Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice
    • Toh SY, Gong J, Du G, Li JZ, Yang S, et al. (2008) Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One 3: e2890.
    • (2008) PLoS One , vol.3
    • Toh, S.Y.1    Gong, J.2    Du, G.3    Li, J.Z.4    Yang, S.5
  • 43
    • 1442352339 scopus 로고    scopus 로고
    • Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach
    • Bays H, Mandarino L, DeFronzo RA, (2004) Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab 89: 463-478.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 463-478
    • Bays, H.1    Mandarino, L.2    DeFronzo, R.A.3
  • 44
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction
    • Boden G, Shulman GI, (2002) Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 32 (Suppl 3): 14-23.
    • (2002) Eur J Clin Invest , vol.32 , Issue.SUPPL. 3 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 45
    • 0141755328 scopus 로고    scopus 로고
    • A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
    • Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, et al. (2003) A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes 52: 2461-2474.
    • (2003) Diabetes , vol.52 , pp. 2461-2474
    • Kashyap, S.1    Belfort, R.2    Gastaldelli, A.3    Pratipanawatr, T.4    Berria, R.5
  • 46
    • 0028849148 scopus 로고
    • Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects
    • Paolisso G, Gambardella A, Amato L, Tortoriello R, D'Amore A, et al. (1995) Opposite effects of short- and long-term fatty acid infusion on insulin secretion in healthy subjects. Diabetologia 38: 1295-1299.
    • (1995) Diabetologia , vol.38 , pp. 1295-1299
    • Paolisso, G.1    Gambardella, A.2    Amato, L.3    Tortoriello, R.4    D'Amore, A.5
  • 47
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme A, Virbasius JV, Puri V, Czech MP, (2008) Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 9: 367-377.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 48
    • 0032080022 scopus 로고    scopus 로고
    • CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor
    • Inohara N, Koseki T, Chen S, Wu X, Nunez G, (1998) CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. Embo J 17: 2526-2533.
    • (1998) Embo J , vol.17 , pp. 2526-2533
    • Inohara, N.1    Koseki, T.2    Chen, S.3    Wu, X.4    Nunez, G.5


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