메뉴 건너뛰기




Volumn 6, Issue 12, 2011, Pages

Radiation-Induced carcinogenesis: Mechanistically based differences between Gamma-Rays and neutrons, and interactions with DMBA

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE;

EID: 83355168956     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028559     Document Type: Article
Times cited : (28)

References (69)
  • 1
    • 70149111720 scopus 로고    scopus 로고
    • Radiation-induced mammary carcinogenesis in rodent models: what's different from chemical carcinogenesis?
    • Imaoka T, Nishimura M, Iizuka D, Daino K, Takabatake T, et al. (2009) Radiation-induced mammary carcinogenesis in rodent models: what's different from chemical carcinogenesis? J Radiat Res (Tokyo) 50: 281-293.
    • (2009) J Radiat Res (Tokyo) , vol.50 , pp. 281-293
    • Imaoka, T.1    Nishimura, M.2    Iizuka, D.3    Daino, K.4    Takabatake, T.5
  • 2
    • 33846190671 scopus 로고    scopus 로고
    • Secondary carcinogenesis in patients treated with radiation: a review of data on radiation-induced cancers in human, non-human primate, canine and rodent subjects
    • Suit H, Goldberg S, Niemierko A, Ancukiewicz M, Hall E, et al. (2007) Secondary carcinogenesis in patients treated with radiation: a review of data on radiation-induced cancers in human, non-human primate, canine and rodent subjects. Radiat Res 167: 12-42.
    • (2007) Radiat Res , vol.167 , pp. 12-42
    • Suit, H.1    Goldberg, S.2    Niemierko, A.3    Ancukiewicz, M.4    Hall, E.5
  • 3
    • 0036300068 scopus 로고    scopus 로고
    • Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates
    • Cornforth MN, Bailey SM, Goodwin EH, (2002) Dose responses for chromosome aberrations produced in noncycling primary human fibroblasts by alpha particles, and by gamma rays delivered at sublimiting low dose rates. Radiat Res 158: 43-53.
    • (2002) Radiat Res , vol.158 , pp. 43-53
    • Cornforth, M.N.1    Bailey, S.M.2    Goodwin, E.H.3
  • 4
    • 67849090655 scopus 로고    scopus 로고
    • Dose response of gamma rays and iron nuclei for induction of chromosomal aberrations in normal and repair-deficient cell lines
    • George KA, Hada M, Jackson LJ, Elliott T, Kawata T, et al. (2009) Dose response of gamma rays and iron nuclei for induction of chromosomal aberrations in normal and repair-deficient cell lines. Radiat Res 171: 752-763.
    • (2009) Radiat Res , vol.171 , pp. 752-763
    • George, K.A.1    Hada, M.2    Jackson, L.J.3    Elliott, T.4    Kawata, T.5
  • 5
    • 0346965729 scopus 로고    scopus 로고
    • Quantitative analysis of biological responses to ionizing radiation, including dose, irradiation time, and dose rate
    • Magae J, Hoshi Y, Furukawa C, Kawakami Y, Ogata H, (2003) Quantitative analysis of biological responses to ionizing radiation, including dose, irradiation time, and dose rate. Radiat Res 160: 543-548.
    • (2003) Radiat Res , vol.160 , pp. 543-548
    • Magae, J.1    Hoshi, Y.2    Furukawa, C.3    Kawakami, Y.4    Ogata, H.5
  • 6
    • 0035139873 scopus 로고    scopus 로고
    • Estimated risks of radiation-induced fatal cancer from pediatric CT
    • Brenner D, Elliston C, Hall E, Berdon W, (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR Am J Roentgenol 176: 289-296.
    • (2001) AJR Am J Roentgenol , vol.176 , pp. 289-296
    • Brenner, D.1    Elliston, C.2    Hall, E.3    Berdon, W.4
  • 7
    • 0036295313 scopus 로고    scopus 로고
    • Do low dose-rate bystander effects influence domestic radon risks?
    • Brenner DJ, Sachs RK, (2002) Do low dose-rate bystander effects influence domestic radon risks? Int J Radiat Biol 78: 593-604.
    • (2002) Int J Radiat Biol , vol.78 , pp. 593-604
    • Brenner, D.J.1    Sachs, R.K.2
  • 8
    • 0034839833 scopus 로고    scopus 로고
    • The role of promotion in carcinogenesis from protracted high-LET exposure
    • Curtis SB, Luebeck EG, Hazelton WD, Moolgavkar SH, (2001) The role of promotion in carcinogenesis from protracted high-LET exposure. Phys Med 17 (Suppl 1): 157-160.
    • (2001) Phys Med , vol.17 , Issue.SUPPL. 1 , pp. 157-160
    • Curtis, S.B.1    Luebeck, E.G.2    Hazelton, W.D.3    Moolgavkar, S.H.4
  • 10
    • 0029165389 scopus 로고
    • Radon-exposed underground miners and inverse dose-rate (protraction enhancement) effects
    • Lubin JH, Boice JD Jr, Edling C, Hornung RW, Howe G, et al. (1995) Radon-exposed underground miners and inverse dose-rate (protraction enhancement) effects. Health Phys 69: 494-500.
    • (1995) Health Phys , vol.69 , pp. 494-500
    • Lubin, J.H.1    Boice Jr., J.D.2    Edling, C.3    Hornung, R.W.4    Howe, G.5
  • 11
    • 0036023749 scopus 로고    scopus 로고
    • Double strand break rejoining after irradiation of human fibroblasts with X rays or alpha particles: PFGE studies and numerical models
    • Pinto M, Prise KM, Michael BD, (2002) Double strand break rejoining after irradiation of human fibroblasts with X rays or alpha particles: PFGE studies and numerical models. Radiat Prot Dosimetry 99: 133-136.
    • (2002) Radiat Prot Dosimetry , vol.99 , pp. 133-136
    • Pinto, M.1    Prise, K.M.2    Michael, B.D.3
  • 12
    • 0031732705 scopus 로고    scopus 로고
    • The mechanistic basis of the linear-quadratic formalism
    • Sachs RK, Brenner DJ, (1998) The mechanistic basis of the linear-quadratic formalism. Med Phys 25: 2071-2073.
    • (1998) Med Phys , vol.25 , pp. 2071-2073
    • Sachs, R.K.1    Brenner, D.J.2
  • 13
    • 0030796648 scopus 로고    scopus 로고
    • The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair
    • Sachs RK, Hahnfeld P, Brenner DJ, (1997) The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair. Int J Radiat Biol 72: 351-374.
    • (1997) Int J Radiat Biol , vol.72 , pp. 351-374
    • Sachs, R.K.1    Hahnfeld, P.2    Brenner, D.J.3
  • 14
    • 0036023773 scopus 로고    scopus 로고
    • Inactivation cross sections for mammalian cells exposed to charged particles: a phenomenological approach
    • Belloni F, Bettega D, Calzolari P, Cherubini R, Massariello P, et al. (2002) Inactivation cross sections for mammalian cells exposed to charged particles: a phenomenological approach. Radiat Prot Dosimetry 99: 199-202.
    • (2002) Radiat Prot Dosimetry , vol.99 , pp. 199-202
    • Belloni, F.1    Bettega, D.2    Calzolari, P.3    Cherubini, R.4    Massariello, P.5
  • 15
    • 0242658550 scopus 로고    scopus 로고
    • Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect
    • Azzam EI, de Toledo SM, Little JB, (2003) Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect. Oncogene 22: 7050-7057.
    • (2003) Oncogene , vol.22 , pp. 7050-7057
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 16
    • 0037171647 scopus 로고    scopus 로고
    • Cellular communication and bystander effects: a critical review for modelling low-dose radiation action
    • Ballarini F, Biaggi M, Ottolenghi A, Sapora O, (2002) Cellular communication and bystander effects: a critical review for modelling low-dose radiation action. Mutat Res 501: 1-12.
    • (2002) Mutat Res , vol.501 , pp. 1-12
    • Ballarini, F.1    Biaggi, M.2    Ottolenghi, A.3    Sapora, O.4
  • 17
    • 0038275987 scopus 로고    scopus 로고
    • The bystander effect
    • Hall EJ, (2003) The bystander effect. Health Phys 85: 31-35.
    • (2003) Health Phys , vol.85 , pp. 31-35
    • Hall, E.J.1
  • 18
    • 33744997893 scopus 로고    scopus 로고
    • Cyclooxygenase-2 as a signaling molecule in radiation-induced bystander effect
    • Hei TK, (2006) Cyclooxygenase-2 as a signaling molecule in radiation-induced bystander effect. Mol Carcinog 45: 455-460.
    • (2006) Mol Carcinog , vol.45 , pp. 455-460
    • Hei, T.K.1
  • 19
    • 33749858414 scopus 로고    scopus 로고
    • Lauriston S. Taylor lecture: nontargeted effects of radiation: implications for low-dose exposures
    • Little JB, (2006) Lauriston S. Taylor lecture: nontargeted effects of radiation: implications for low-dose exposures. Health Phys 91: 416-426.
    • (2006) Health Phys , vol.91 , pp. 416-426
    • Little, J.B.1
  • 20
    • 0034267574 scopus 로고    scopus 로고
    • Genomic instability, bystander effects and radiation risks: implications for development of protection strategies for man and the environment
    • Mothersill C, Seymour C, (2000) Genomic instability, bystander effects and radiation risks: implications for development of protection strategies for man and the environment. Radiats Biol Radioecol 40: 615-620.
    • (2000) Radiats Biol Radioecol , vol.40 , pp. 615-620
    • Mothersill, C.1    Seymour, C.2
  • 21
    • 0036250160 scopus 로고    scopus 로고
    • Relationship between radiation-induced low-dose hypersensitivity and the bystander effect
    • Mothersill C, Seymour CB, Joiner MC, (2002) Relationship between radiation-induced low-dose hypersensitivity and the bystander effect. Radiat Res 157: 526-532.
    • (2002) Radiat Res , vol.157 , pp. 526-532
    • Mothersill, C.1    Seymour, C.B.2    Joiner, M.C.3
  • 22
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of alpha-particles
    • Nagasawa H, Little JB, (1992) Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res 52: 6394-6396.
    • (1992) Cancer Res , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 23
    • 0348226547 scopus 로고    scopus 로고
    • Low-dose studies of bystander cell killing with targeted soft X rays
    • Schettino G, Folkard M, Prise KM, Vojnovic B, Held KD, et al. (2003) Low-dose studies of bystander cell killing with targeted soft X rays. Radiat Res 160: 505-511.
    • (2003) Radiat Res , vol.160 , pp. 505-511
    • Schettino, G.1    Folkard, M.2    Prise, K.M.3    Vojnovic, B.4    Held, K.D.5
  • 24
    • 34249315106 scopus 로고    scopus 로고
    • DNA Double-Strand Breaks Form in Bystander Cells after Microbeam Irradiation of Three-dimensional Human Tissue Models
    • Sedelnikova OA, Nakamura A, Kovalchuk O, Koturbash I, Mitchell SA, et al. (2007) DNA Double-Strand Breaks Form in Bystander Cells after Microbeam Irradiation of Three-dimensional Human Tissue Models. Cancer Res 67: 4295-4302.
    • (2007) Cancer Res , vol.67 , pp. 4295-4302
    • Sedelnikova, O.A.1    Nakamura, A.2    Kovalchuk, O.3    Koturbash, I.4    Mitchell, S.A.5
  • 25
    • 33646046779 scopus 로고    scopus 로고
    • Bystander-induced differentiation: a major response to targeted irradiation of a urothelial explant model
    • Belyakov OV, Folkard M, Mothersill C, Prise KM, Michael BD, (2006) Bystander-induced differentiation: a major response to targeted irradiation of a urothelial explant model. Mutat Res 597: 43-49.
    • (2006) Mutat Res , vol.597 , pp. 43-49
    • Belyakov, O.V.1    Folkard, M.2    Mothersill, C.3    Prise, K.M.4    Michael, B.D.5
  • 26
    • 0037600691 scopus 로고    scopus 로고
    • Domestic radon risks may be dominated by bystander effects-but the risks are unlikely to be greater than we thought
    • Brenner DJ, Sachs RK, (2003) Domestic radon risks may be dominated by bystander effects-but the risks are unlikely to be greater than we thought. Health Phys 85: 103-108.
    • (2003) Health Phys , vol.85 , pp. 103-108
    • Brenner, D.J.1    Sachs, R.K.2
  • 27
    • 38849124983 scopus 로고    scopus 로고
    • Biophysical models of radiation bystander effects: 1. Spatial effects in three-dimensional tissues
    • Shuryak I, Sachs RK, Brenner DJ, (2007) Biophysical models of radiation bystander effects: 1. Spatial effects in three-dimensional tissues. Radiat Res 168: 741-749.
    • (2007) Radiat Res , vol.168 , pp. 741-749
    • Shuryak, I.1    Sachs, R.K.2    Brenner, D.J.3
  • 28
    • 0033765546 scopus 로고    scopus 로고
    • Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis
    • Lyng FM, Seymour CB, Mothersill C, (2000) Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis. Br J Cancer 83: 1223-1230.
    • (2000) Br J Cancer , vol.83 , pp. 1223-1230
    • Lyng, F.M.1    Seymour, C.B.2    Mothersill, C.3
  • 29
    • 6344259973 scopus 로고    scopus 로고
    • Biological responses in known bystander cells relative to known microbeam-irradiated cells
    • Ponnaiya B, Jenkins-Baker G, Brenner DJ, Hall EJ, Randers-Pehrson G, et al. (2004) Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiat Res 162: 426-432.
    • (2004) Radiat Res , vol.162 , pp. 426-432
    • Ponnaiya, B.1    Jenkins-Baker, G.2    Brenner, D.J.3    Hall, E.J.4    Randers-Pehrson, G.5
  • 30
    • 0034759209 scopus 로고    scopus 로고
    • The two-stage clonal expansion model as an example of a biologically based model of radiation-induced cancer
    • Heidenreich WF, Paretzke HG, (2001) The two-stage clonal expansion model as an example of a biologically based model of radiation-induced cancer. Radiat Res 156: 678-681.
    • (2001) Radiat Res , vol.156 , pp. 678-681
    • Heidenreich, W.F.1    Paretzke, H.G.2
  • 31
    • 0019047847 scopus 로고
    • Multistage models for carcinogenesis
    • Moolgavkar S, (1980) Multistage models for carcinogenesis. J Natl Cancer Inst 65: 215-216.
    • (1980) J Natl Cancer Inst , vol.65 , pp. 215-216
    • Moolgavkar, S.1
  • 32
    • 0017809827 scopus 로고
    • The multistage theory of carcinogenesis and the age distribution of cancer in man
    • Moolgavkar SH, (1978) The multistage theory of carcinogenesis and the age distribution of cancer in man. J Natl Cancer Inst 61: 49-52.
    • (1978) J Natl Cancer Inst , vol.61 , pp. 49-52
    • Moolgavkar, S.H.1
  • 33
    • 0033588227 scopus 로고    scopus 로고
    • Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene
    • Miyata M, Kudo G, Lee YH, Yang TJ, Gelboin HV, et al. (1999) Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene. J Biol Chem 274: 23963-23968.
    • (1999) J Biol Chem , vol.274 , pp. 23963-23968
    • Miyata, M.1    Kudo, G.2    Lee, Y.H.3    Yang, T.J.4    Gelboin, H.V.5
  • 34
    • 34447540174 scopus 로고    scopus 로고
    • Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice
    • Gao J, Lauer FT, Mitchell LA, Burchiel SW, (2007) Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice. Toxicol Sci 98: 137-144.
    • (2007) Toxicol Sci , vol.98 , pp. 137-144
    • Gao, J.1    Lauer, F.T.2    Mitchell, L.A.3    Burchiel, S.W.4
  • 35
    • 0036168607 scopus 로고    scopus 로고
    • Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation
    • Kleiner HE, Vulimiri SV, Reed MJ, Uberecken A, DiGiovanni J, (2002) Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation. Chem Res Toxicol 15: 226-235.
    • (2002) Chem Res Toxicol , vol.15 , pp. 226-235
    • Kleiner, H.E.1    Vulimiri, S.V.2    Reed, M.J.3    Uberecken, A.4    DiGiovanni, J.5
  • 36
    • 21244488225 scopus 로고    scopus 로고
    • Evidence for complexity at the nanometer scale of radiation-induced DNA DSBs as a determinant of rejoining kinetics
    • Pinto M, Prise KM, Michael BD, (2005) Evidence for complexity at the nanometer scale of radiation-induced DNA DSBs as a determinant of rejoining kinetics. Radiat Res 164: 73-85.
    • (2005) Radiat Res , vol.164 , pp. 73-85
    • Pinto, M.1    Prise, K.M.2    Michael, B.D.3
  • 37
    • 36549058032 scopus 로고    scopus 로고
    • Misrejoined, residual double strand DNA breaks and radiosensitivity in human tumor cell lines
    • Saleh EM, El-Awady RA, (2005) Misrejoined, residual double strand DNA breaks and radiosensitivity in human tumor cell lines. J Egypt Natl Canc Inst 17: 93-102.
    • (2005) J Egypt Natl Canc Inst , vol.17 , pp. 93-102
    • Saleh, E.M.1    El-Awady, R.A.2
  • 39
    • 33745700690 scopus 로고    scopus 로고
    • Biologically based analysis of lung cancer incidence in a large Canadian occupational cohort with low-dose ionizing radiation exposure, and comparison with Japanese atomic bomb survivors
    • Hazelton WD, Moolgavkar SH, Curtis SB, Zielinski JM, Ashmore JP, et al. (2006) Biologically based analysis of lung cancer incidence in a large Canadian occupational cohort with low-dose ionizing radiation exposure, and comparison with Japanese atomic bomb survivors. J Toxicol Environ Health A 69: 1013-1038.
    • (2006) J Toxicol Environ Health A , vol.69 , pp. 1013-1038
    • Hazelton, W.D.1    Moolgavkar, S.H.2    Curtis, S.B.3    Zielinski, J.M.4    Ashmore, J.P.5
  • 40
    • 13244275088 scopus 로고    scopus 로고
    • Interpretation by modelling of observations in radon radiation carcinogenesis
    • Heidenreich WF, Paretzke HG, (2004) Interpretation by modelling of observations in radon radiation carcinogenesis. Radiat Prot Dosimetry 112: 501-507.
    • (2004) Radiat Prot Dosimetry , vol.112 , pp. 501-507
    • Heidenreich, W.F.1    Paretzke, H.G.2
  • 41
    • 66149141471 scopus 로고    scopus 로고
    • Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations
    • Peng Y, Brown N, Finnon R, Warner CL, Liu X, et al. (2009) Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations. Radiat Res 171: 474-483.
    • (2009) Radiat Res , vol.171 , pp. 474-483
    • Peng, Y.1    Brown, N.2    Finnon, R.3    Warner, C.L.4    Liu, X.5
  • 42
    • 77956152948 scopus 로고    scopus 로고
    • Murine models of human acute myeloid leukemia
    • Fortier JM, Graubert TA, (2010) Murine models of human acute myeloid leukemia. Cancer Treat Res 145: 183-196.
    • (2010) Cancer Treat Res , vol.145 , pp. 183-196
    • Fortier, J.M.1    Graubert, T.A.2
  • 43
    • 0020040120 scopus 로고
    • Detection of ductal dysplasia in mammary outgrowths derived from carcinogen-treated virgin female BALB/c mice
    • Ethier SP, Ullrich RL, (1982) Detection of ductal dysplasia in mammary outgrowths derived from carcinogen-treated virgin female BALB/c mice. Cancer Res 42: 1753-1760.
    • (1982) Cancer Res , vol.42 , pp. 1753-1760
    • Ethier, S.P.1    Ullrich, R.L.2
  • 44
    • 0021202144 scopus 로고
    • Factors influencing expression of mammary ductal dysplasia in cell dissociation-derived murine mammary outgrowths
    • Ethier SP, Ullrich RL, (1984) Factors influencing expression of mammary ductal dysplasia in cell dissociation-derived murine mammary outgrowths. Cancer Res 44: 4523-4527.
    • (1984) Cancer Res , vol.44 , pp. 4523-4527
    • Ethier, S.P.1    Ullrich, R.L.2
  • 45
    • 31544478262 scopus 로고    scopus 로고
    • The time and spatial effects of bystander response in mammalian cells induced by low dose radiation
    • Hu B, Wu L, Han W, Zhang L, Chen S, et al. (2006) The time and spatial effects of bystander response in mammalian cells induced by low dose radiation. Carcinogenesis 27: 245-251.
    • (2006) Carcinogenesis , vol.27 , pp. 245-251
    • Hu, B.1    Wu, L.2    Han, W.3    Zhang, L.4    Chen, S.5
  • 46
    • 70349785749 scopus 로고    scopus 로고
    • A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: approach
    • Shuryak I, Hahnfeldt P, Hlatky L, Sachs RK, Brenner DJ, (2009) A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: approach. Radiat Environ Biophys 48: 263-274.
    • (2009) Radiat Environ Biophys , vol.48 , pp. 263-274
    • Shuryak, I.1    Hahnfeldt, P.2    Hlatky, L.3    Sachs, R.K.4    Brenner, D.J.5
  • 47
    • 70349787216 scopus 로고    scopus 로고
    • A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation
    • Shuryak I, Hahnfeldt P, Hlatky L, Sachs RK, Brenner DJ, (2009) A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. Radiat Environ Biophys 48: 275-286.
    • (2009) Radiat Environ Biophys , vol.48 , pp. 275-286
    • Shuryak, I.1    Hahnfeldt, P.2    Hlatky, L.3    Sachs, R.K.4    Brenner, D.J.5
  • 48
    • 0036698236 scopus 로고    scopus 로고
    • A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model
    • Curtis SB, Luebeck EG, Hazelton WD, Moolgavkar SH, (2002) A new perspective of carcinogenesis from protracted high-LET radiation arises from the two-stage clonal expansion model. Adv Space Res 30: 937-944.
    • (2002) Adv Space Res , vol.30 , pp. 937-944
    • Curtis, S.B.1    Luebeck, E.G.2    Hazelton, W.D.3    Moolgavkar, S.H.4
  • 49
    • 0034540916 scopus 로고    scopus 로고
    • The importance of promotion in lung carcinogenesis for protracted exposures to radon and radon progeny
    • discussion 730-731
    • Luebeck EG, Curtis SB, Hazelton WD, Moolgavkar SH, (2000) The importance of promotion in lung carcinogenesis for protracted exposures to radon and radon progeny. Radiat Res 154: 730;discussion 730-731.
    • (2000) Radiat Res , vol.154 , pp. 730
    • Luebeck, E.G.1    Curtis, S.B.2    Hazelton, W.D.3    Moolgavkar, S.H.4
  • 50
    • 0037352269 scopus 로고    scopus 로고
    • Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin
    • Bennett WR, Crew TE, Slack JM, Ward A, (2003) Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin. Development 130: 1079-1088.
    • (2003) Development , vol.130 , pp. 1079-1088
    • Bennett, W.R.1    Crew, T.E.2    Slack, J.M.3    Ward, A.4
  • 52
    • 1642603951 scopus 로고    scopus 로고
    • Socializing with the neighbors: stem cells and their niche
    • Fuchs E, Tumbar T, Guasch G, (2004) Socializing with the neighbors: stem cells and their niche. Cell 116: 769-778.
    • (2004) Cell , vol.116 , pp. 769-778
    • Fuchs, E.1    Tumbar, T.2    Guasch, G.3
  • 53
    • 12944268864 scopus 로고    scopus 로고
    • Organization of stem cells and their progeny in human epidermis
    • Ghazizadeh S, Taichman LB, (2005) Organization of stem cells and their progeny in human epidermis. J Invest Dermatol 124: 367-372.
    • (2005) J Invest Dermatol , vol.124 , pp. 367-372
    • Ghazizadeh, S.1    Taichman, L.B.2
  • 54
    • 28444486367 scopus 로고    scopus 로고
    • Stem cell niche: structure and function
    • Li L, Xie T, (2005) Stem cell niche: structure and function. Annu Rev Cell Dev Biol 21: 605-631.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 605-631
    • Li, L.1    Xie, T.2
  • 55
    • 0036428657 scopus 로고    scopus 로고
    • Keratinocyte stem cells: a commentary
    • Potten CS, Booth C, (2002) Keratinocyte stem cells: a commentary. J Invest Dermatol 119: 888-899.
    • (2002) J Invest Dermatol , vol.119 , pp. 888-899
    • Potten, C.S.1    Booth, C.2
  • 56
    • 0034712075 scopus 로고    scopus 로고
    • Stem cells in epithelial tissues
    • Slack JM, (2000) Stem cells in epithelial tissues. Science 287: 1431-1433.
    • (2000) Science , vol.287 , pp. 1431-1433
    • Slack, J.M.1
  • 57
    • 12344264072 scopus 로고    scopus 로고
    • Colonization of adjacent stem cell compartments by mutant keratinocytes
    • Brash DE, Zhang W, Grossman D, Takeuchi S, (2005) Colonization of adjacent stem cell compartments by mutant keratinocytes. Semin Cancer Biol 15: 97-102.
    • (2005) Semin Cancer Biol , vol.15 , pp. 97-102
    • Brash, D.E.1    Zhang, W.2    Grossman, D.3    Takeuchi, S.4
  • 58
    • 34547655761 scopus 로고    scopus 로고
    • Biomechanical modelling of colorectal crypt budding and fission
    • Edwards CM, Chapman SJ, (2007) Biomechanical modelling of colorectal crypt budding and fission. Bull Math Biol 69: 1927-1942.
    • (2007) Bull Math Biol , vol.69 , pp. 1927-1942
    • Edwards, C.M.1    Chapman, S.J.2
  • 59
    • 31444433936 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
    • Greaves LC, Preston SL, Tadrous PJ, Taylor RW, Barron MJ, et al. (2006) Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission. Proc Natl Acad Sci U S A 103: 714-719.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 714-719
    • Greaves, L.C.1    Preston, S.L.2    Tadrous, P.J.3    Taylor, R.W.4    Barron, M.J.5
  • 60
  • 61
    • 0035923598 scopus 로고    scopus 로고
    • Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations
    • Zhang W, Remenyik E, Zelterman D, Brash DE, Wikonkal NM, (2001) Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations. Proc Natl Acad Sci U S A 98: 13948-13953.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13948-13953
    • Zhang, W.1    Remenyik, E.2    Zelterman, D.3    Brash, D.E.4    Wikonkal, N.M.5
  • 63
    • 34548841127 scopus 로고    scopus 로고
    • Ageing: from stem to stern
    • Brunet A, Rando TA, (2007) Ageing: from stem to stern. Nature 449: 288-291.
    • (2007) Nature , vol.449 , pp. 288-291
    • Brunet, A.1    Rando, T.A.2
  • 64
    • 34248354983 scopus 로고    scopus 로고
    • Loss of stem cell regenerative capacity within aged niches
    • Carlson ME, Conboy IM, (2007) Loss of stem cell regenerative capacity within aged niches. Aging Cell 6: 371-382.
    • (2007) Aging Cell , vol.6 , pp. 371-382
    • Carlson, M.E.1    Conboy, I.M.2
  • 65
    • 0036206864 scopus 로고    scopus 로고
    • Age distribution of cancer in mice: the incidence turnover at old age
    • Pompei F, Polkanov M, Wilson R, (2001) Age distribution of cancer in mice: the incidence turnover at old age. Toxicol Ind Health 17: 7-16.
    • (2001) Toxicol Ind Health , vol.17 , pp. 7-16
    • Pompei, F.1    Polkanov, M.2    Wilson, R.3
  • 66
    • 1942502247 scopus 로고    scopus 로고
    • A quantitative model of cellular senescence influence on cancer and longevity
    • Pompei F, Wilson R, (2002) A quantitative model of cellular senescence influence on cancer and longevity. Toxicol Ind Health 18: 365-376.
    • (2002) Toxicol Ind Health , vol.18 , pp. 365-376
    • Pompei, F.1    Wilson, R.2
  • 67
    • 34548153747 scopus 로고    scopus 로고
    • How stem cells age and why this makes us grow old
    • Sharpless NE, DePinho RA, (2007) How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 8: 703-713.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 703-713
    • Sharpless, N.E.1    DePinho, R.A.2
  • 68
    • 77956217976 scopus 로고    scopus 로고
    • The balance between initiation and promotion in radiation-induced murine carcinogenesis
    • Shuryak I, Ullrich RL, Sachs RK, Brenner DJ, (2010) The balance between initiation and promotion in radiation-induced murine carcinogenesis. Radiat Res 174: 357-366.
    • (2010) Radiat Res , vol.174 , pp. 357-366
    • Shuryak, I.1    Ullrich, R.L.2    Sachs, R.K.3    Brenner, D.J.4
  • 69
    • 0031803003 scopus 로고    scopus 로고
    • The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships
    • Brenner DJ, Hlatky LR, Hahnfeldt PJ, Huang Y, Sachs RK, (1998) The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships. Radiat Res 150: 83-91.
    • (1998) Radiat Res , vol.150 , pp. 83-91
    • Brenner, D.J.1    Hlatky, L.R.2    Hahnfeldt, P.J.3    Huang, Y.4    Sachs, R.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.