The effect of environmental pH on polymeric transfection efficiency

Biomaterials

Volumn 33, Issue 5, 2012, Pages 1651-1662

  Kang, Han Chang ^a,b   Samsonova, Olga ^a,c   Kang, Sun Woong ^a   Bae, You Han ^a,d  

^a UNIVERSITY OF UTAH   (United States)

^b The Catholic University of Korea   (South Korea)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d Utah Inha DDS and Advanced Theapeutics Research Center   (South Korea)

Author keywords

Extracellular pH; Poly(l lysine); Polyethyleneimine; Polymeric gene delivery; Solution pH

Indexed keywords

EXTRACELLULAR PH; L-LYSINE; POLYETHYLENEIMINE; POLYMERIC GENE DELIVERY; SOLUTION PH;

AMINO ACIDS; CELL CULTURE; EFFICIENCY; ENZYME ACTIVITY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; MOLECULAR BIOLOGY; PH EFFECTS;

POLYMERS;

DNA; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; POLYPLEX; PROTON; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CELL CYCLE PHASE; CELL PH; COMPLEX FORMATION; CULTURE MEDIUM; CYTOSOL; ELECTRICAL PARAMETERS; ENDOCYTOSIS; ENDOSOME; EXTRACELLULAR PH; EXTRACELLULAR SPACE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IONIZATION; MITOSIS; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTON BUFFERING CAPACITY; SURFACE CHARGE;

CELL CYCLE; CELL LINE, TUMOR; CULTURE MEDIA; DNA; EXTRACELLULAR SPACE; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; PARTICLE SIZE; POLYETHYLENEIMINE; POLYMERS; SUBCELLULAR FRACTIONS; SURFACE PROPERTIES; TRANSFECTION;

EID: 83355162674     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.11.006     Document Type: Article

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