A reducible polycationic gene vector derived from thiolated low molecular weight branched polyethyleneimine linked by 2-iminothiolane

Biomaterials

Volumn 32, Issue 4, 2011, Pages 1193-1203

  Kang, Han Chang ^a   Kang, Ho Jung ^b   Bae, You Han ^a,c  

^a UNIVERSITY OF UTAH   (United States)

^b Kyung Hee University   (South Korea)

^c Utah Inha DDS and Advanced Theapeutics Research Center   (South Korea)

Author keywords

2 iminothiolane; Branched polyethyleneimine; Non viral gene vector; Polymeric gene delivery; Reducible polycations; Reducible polymer

Indexed keywords

2-IMINOTHIOLANE; NONVIRAL; POLYCATIONS; POLYETHYLENEIMINE; POLYMERIC GENE DELIVERY; REDUCIBLE POLYMER;

CYTOTOXICITY; GENE THERAPY; GENE TRANSFER; ION EXCHANGE; MOLECULAR WEIGHT; VECTORS;

POLYMERS;

2 IMINOTHIOLANE; PLASMID DNA; POLYCATION; POLYETHYLENEIMINE DERIVATIVE;

ARTICLE; CELL NUCLEUS; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DNA SYNTHESIS; GENE VECTOR; GOLD STANDARD; HUMAN; HUMAN CELL; ION EXCHANGE; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; OXIDATION; PARTICLE SIZE; PRIORITY JOURNAL; THIOLATION;

CROSS-LINKING REAGENTS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEK293 CELLS; HUMANS; IMIDOESTERS; MATERIALS TESTING; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; POLYAMINES; POLYETHYLENEIMINE; SULFHYDRYL COMPOUNDS; TRANSFECTION;

EID: 78649451263     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.08.079     Document Type: Article

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