The nonsteroidal anti-inflammatory drug celecoxib suppresses the growth and induces apoptosis of human glioblastoma cells via the NF-κB pathway

Journal of Neuro-Oncology

Volumn 106, Issue 1, 2012, Pages 99-109

  Sareddy, Gangadhara Reddy ^a   Geeviman, Khamushavalli ^a   Ramulu, Chinta ^a   Babu, Phanithi Prakash ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Celecoxib; Glioblastoma; I B ; IKK; NF B; p50; p65

Indexed keywords

CASPASE 3; CASPASE 8; CELECOXIB; DNA; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TUMOR NECROSIS FACTOR ALPHA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVITY; GLIOBLASTOMA; NICK END LABELING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REPORTER GENE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; COLONY-FORMING UNITS ASSAY; COLORING AGENTS; CYCLOOXYGENASE 2 INHIBITORS; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GLIOBLASTOMA; HUMANS; I-KAPPA B PROTEINS; IN SITU NICK-END LABELING; NF-KAPPA B; PROTEIN TRANSPORT; PYRAZOLES; SIGNAL TRANSDUCTION; SULFONAMIDES; TETRAZOLIUM SALTS; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83055194567     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-011-0662-x     Document Type: Article

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