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Volumn 6, Issue 12, 2011, Pages

Latent Epstein-Barr virus can inhibit apoptosis in B cells by blocking the induction of NOXA expression

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; EPSTEIN BARR VIRUS ANTIGEN; EPSTEIN BARR VIRUS ANTIGEN 1; EPSTEIN BARR VIRUS ANTIGEN 2; EPSTEIN BARR VIRUS ANTIGEN 3A; EPSTEIN BARR VIRUS ANTIGEN 3B; EPSTEIN BARR VIRUS ANTIGEN 3C; ETOPOSIDE; IONOMYCIN; PROTEIN EBER; PROTEIN LMP; PROTEIN NOXA; PROTEIN P53; SHORT HAIRPIN RNA; STAUROSPORINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; MESSENGER RNA; PMAIP1 PROTEIN, HUMAN; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 83055182225     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028506     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 4944266319 scopus 로고    scopus 로고
    • Epstein-Barr virus: 40 years on
    • Young LS, Rickinson AB, (2004) Epstein-Barr virus: 40 years on. Nat Rev Cancer 4: 757-768.
    • (2004) Nat Rev Cancer , vol.4 , pp. 757-768
    • Young, L.S.1    Rickinson, A.B.2
  • 3
    • 1642334164 scopus 로고    scopus 로고
    • Persistence of the Epstein-Barr virus and the origins of associated lymphomas
    • Thorley-Lawson DA, Gross A, (2004) Persistence of the Epstein-Barr virus and the origins of associated lymphomas. N Engl J Med 350: 1328-1337.
    • (2004) N Engl J Med , vol.350 , pp. 1328-1337
    • Thorley-Lawson, D.A.1    Gross, A.2
  • 4
    • 56349158720 scopus 로고    scopus 로고
    • The curious case of the tumour virus: 50 years of Burkitt's lymphoma
    • Thorley-Lawson DA, Allday MJ, (2008) The curious case of the tumour virus: 50 years of Burkitt's lymphoma. Nat Rev Microbiol 6: 913-924.
    • (2008) Nat Rev Microbiol , vol.6 , pp. 913-924
    • Thorley-Lawson, D.A.1    Allday, M.J.2
  • 5
    • 64049099870 scopus 로고    scopus 로고
    • The intersection of Epstein-Barr virus with the germinal center
    • Roughan JE, Thorley-Lawson DA, (2009) The intersection of Epstein-Barr virus with the germinal center. J Virol.
    • (2009) J Virol
    • Roughan, J.E.1    Thorley-Lawson, D.A.2
  • 6
    • 0035967425 scopus 로고    scopus 로고
    • Biology and disease associations of Epstein-Barr virus
    • Crawford DH, (2001) Biology and disease associations of Epstein-Barr virus. Philos Trans R Soc Lond B Biol Sci 356: 461-473.
    • (2001) Philos Trans R Soc Lond B Biol Sci , vol.356 , pp. 461-473
    • Crawford, D.H.1
  • 7
    • 0033575762 scopus 로고    scopus 로고
    • Epstein-barr virus-infected resting memory B cells, not proliferating lymphoblasts, accumulate in the peripheral blood of immunosuppressed patients
    • Babcock GJ, Decker LL, Freeman RB, Thorley-Lawson DA, (1999) Epstein-barr virus-infected resting memory B cells, not proliferating lymphoblasts, accumulate in the peripheral blood of immunosuppressed patients. J Exp Med 190: 567-576.
    • (1999) J Exp Med , vol.190 , pp. 567-576
    • Babcock, G.J.1    Decker, L.L.2    Freeman, R.B.3    Thorley-Lawson, D.A.4
  • 8
    • 0027260656 scopus 로고
    • Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
    • Henderson S, Huen D, Rowe M, Dawson C, Johnson G, et al. (1993) Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. Proc Natl Acad Sci U S A 90: 8479-8483.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 8479-8483
    • Henderson, S.1    Huen, D.2    Rowe, M.3    Dawson, C.4    Johnson, G.5
  • 9
    • 0026465540 scopus 로고
    • The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B
    • Laherty CD, Hu HM, Opipari AW, Wang F, Dixit VM, (1992) The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B. J Biol Chem 267: 24157-24160.
    • (1992) J Biol Chem , vol.267 , pp. 24157-24160
    • Laherty, C.D.1    Hu, H.M.2    Opipari, A.W.3    Wang, F.4    Dixit, V.M.5
  • 10
    • 0344630245 scopus 로고    scopus 로고
    • Epstein-Barr virus provides a survival factor to Burkitt's lymphomas
    • Kennedy G, Komano J, Sugden B, (2003) Epstein-Barr virus provides a survival factor to Burkitt's lymphomas. Proc Natl Acad Sci U S A 100: 14269-14274.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14269-14274
    • Kennedy, G.1    Komano, J.2    Sugden, B.3
  • 12
    • 0029795731 scopus 로고    scopus 로고
    • Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines
    • Wang S, Rowe M, Lundgren E, (1996) Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines. Cancer Res 56: 4610-4613.
    • (1996) Cancer Res , vol.56 , pp. 4610-4613
    • Wang, S.1    Rowe, M.2    Lundgren, E.3
  • 13
    • 0026072991 scopus 로고
    • Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis
    • Gregory CD, Dive C, Henderson S, Smith CA, Williams GT, et al. (1991) Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis. Nature 349: 612-614.
    • (1991) Nature , vol.349 , pp. 612-614
    • Gregory, C.D.1    Dive, C.2    Henderson, S.3    Smith, C.A.4    Williams, G.T.5
  • 14
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, et al. (1991) Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65: 1107-1115.
    • (1991) Cell , vol.65 , pp. 1107-1115
    • Henderson, S.1    Rowe, M.2    Gregory, C.3    Croom-Carter, D.4    Wang, F.5
  • 15
    • 34447270509 scopus 로고    scopus 로고
    • Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A
    • Garibal J, Hollville E, Bell AI, Kelly GL, Renouf B, et al. (2007) Truncated form of the Epstein-Barr virus protein EBNA-LP protects against caspase-dependent apoptosis by inhibiting protein phosphatase 2A. J Virol 81: 7598-7607.
    • (2007) J Virol , vol.81 , pp. 7598-7607
    • Garibal, J.1    Hollville, E.2    Bell, A.I.3    Kelly, G.L.4    Renouf, B.5
  • 16
    • 29144463656 scopus 로고    scopus 로고
    • Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis
    • Altmann M, Hammerschmidt W, (2005) Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol 3: e404.
    • (2005) PLoS Biol , vol.3
    • Altmann, M.1    Hammerschmidt, W.2
  • 18
    • 70749117518 scopus 로고    scopus 로고
    • How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?
    • Allday MJ, (2009) How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma? Semin Cancer Biol 19: 366-376.
    • (2009) Semin Cancer Biol , vol.19 , pp. 366-376
    • Allday, M.J.1
  • 19
    • 42349087843 scopus 로고    scopus 로고
    • Burkitt lymphoma: revisiting the pathogenesis of a virus-associated malignancy
    • Kelly GL, Rickinson AB, (2007) Burkitt lymphoma: revisiting the pathogenesis of a virus-associated malignancy. Hematology Am Soc Hematol Educ Program pp. 277-284.
    • (2007) Hematology Am Soc Hematol Educ Program , pp. 277-284
    • Kelly, G.L.1    Rickinson, A.B.2
  • 20
    • 23244461659 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis
    • Kelly GL, Milner AE, Tierney RJ, Croom-Carter DS, Altmann M, et al. (2005) Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A,-3B, and-3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis. J Virol 79: 10709-10717.
    • (2005) J Virol , vol.79 , pp. 10709-10717
    • Kelly, G.L.1    Milner, A.E.2    Tierney, R.J.3    Croom-Carter, D.S.4    Altmann, M.5
  • 21
    • 33845799610 scopus 로고    scopus 로고
    • Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells
    • Leao M, Anderton E, Wade M, Meekings K, Allday MJ, (2007) Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells. J Virol 81: 248-260.
    • (2007) J Virol , vol.81 , pp. 248-260
    • Leao, M.1    Anderton, E.2    Wade, M.3    Meekings, K.4    Allday, M.J.5
  • 22
    • 38349057842 scopus 로고    scopus 로고
    • Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma
    • Anderton E, Yee J, Smith P, Crook T, White RE, et al. (2008) Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma. Oncogene 27: 421-433.
    • (2008) Oncogene , vol.27 , pp. 421-433
    • Anderton, E.1    Yee, J.2    Smith, P.3    Crook, T.4    White, R.E.5
  • 23
    • 0028951944 scopus 로고
    • Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53
    • Allday MJ, Sinclair A, Parker G, Crawford DH, Farrell PJ, (1995) Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53. Embo J 14: 1382-1391.
    • (1995) Embo J , vol.14 , pp. 1382-1391
    • Allday, M.J.1    Sinclair, A.2    Parker, G.3    Crawford, D.H.4    Farrell, P.J.5
  • 24
    • 33845467396 scopus 로고    scopus 로고
    • Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53
    • O'Nions J, Turner A, Craig R, Allday MJ, (2006) Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53. J Virol 80: 12408-12413.
    • (2006) J Virol , vol.80 , pp. 12408-12413
    • O'Nions, J.1    Turner, A.2    Craig, R.3    Allday, M.J.4
  • 25
    • 63449086437 scopus 로고    scopus 로고
    • An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link
    • Kelly GL, Long HM, Stylianou J, Thomas WA, Leese A, et al. (2009) An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link. PLoS Pathog 5: e1000341.
    • (2009) PLoS Pathog , vol.5
    • Kelly, G.L.1    Long, H.M.2    Stylianou, J.3    Thomas, W.A.4    Leese, A.5
  • 27
    • 0036796086 scopus 로고    scopus 로고
    • EBV framed in Burkitt lymphoma
    • Speck SH, (2002) EBV framed in Burkitt lymphoma. Nat Med 8: 1086-1087.
    • (2002) Nat Med , vol.8 , pp. 1086-1087
    • Speck, S.H.1
  • 28
    • 0036799565 scopus 로고    scopus 로고
    • Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2
    • Kelly G, Bell A, Rickinson A, (2002) Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2. Nat Med 8: 1098-1104.
    • (2002) Nat Med , vol.8 , pp. 1098-1104
    • Kelly, G.1    Bell, A.2    Rickinson, A.3
  • 29
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death
    • Casciola-Rosen L, Nicholson DW, Chong T, Rowan KR, Thornberry NA, et al. (1996) Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J Exp Med 183: 1957-1964.
    • (1996) J Exp Med , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3    Rowan, K.R.4    Thornberry, N.A.5
  • 30
    • 1842843170 scopus 로고    scopus 로고
    • Proliferation and differentiation in isogenic populations of peripheral B cells activated by Epstein-Barr virus or T cell-derived mitogens
    • O'Nions J, Allday MJ, (2004) Proliferation and differentiation in isogenic populations of peripheral B cells activated by Epstein-Barr virus or T cell-derived mitogens. J Gen Virol 85: 881-895.
    • (2004) J Gen Virol , vol.85 , pp. 881-895
    • O'Nions, J.1    Allday, M.J.2
  • 31
    • 78649746843 scopus 로고    scopus 로고
    • Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification
    • White RE, Groves IJ, Turro E, Yee J, Kremmer E, et al. (2010) Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification. PLoS One 5: e13979.
    • (2010) PLoS One , vol.5
    • White, R.E.1    Groves, I.J.2    Turro, E.3    Yee, J.4    Kremmer, E.5
  • 32
    • 0023280501 scopus 로고
    • Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex
    • Pearson GR, Luka J, Petti L, Sample J, Birkenbach M, et al. (1987) Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex. Virology 160: 151-161.
    • (1987) Virology , vol.160 , pp. 151-161
    • Pearson, G.R.1    Luka, J.2    Petti, L.3    Sample, J.4    Birkenbach, M.5
  • 33
    • 77958141684 scopus 로고    scopus 로고
    • Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells
    • Seto E, Moosmann A, Gromminger S, Walz N, Grundhoff A, et al. (2010) Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathog 6.
    • (2010) PLoS Pathog , vol.6
    • Seto, E.1    Moosmann, A.2    Gromminger, S.3    Walz, N.4    Grundhoff, A.5
  • 34
    • 79952206685 scopus 로고    scopus 로고
    • A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus
    • Feederle R, Linnstaedt SD, Bannert H, Lips H, Bencun M, et al. (2011) A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus. PLoS Pathog 7: e1001294.
    • (2011) PLoS Pathog , vol.7
    • Feederle, R.1    Linnstaedt, S.D.2    Bannert, H.3    Lips, H.4    Bencun, M.5
  • 35
    • 0034640281 scopus 로고    scopus 로고
    • Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
    • Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, et al. (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
    • (2000) Science , vol.288 , pp. 1053-1058
    • Oda, E.1    Ohki, R.2    Murasawa, H.3    Nemoto, J.4    Shibue, T.5
  • 36
    • 0036392058 scopus 로고    scopus 로고
    • Role of genetic and epigenetic changes in Burkitt lymphoma
    • Lindstrom MS, Wiman KG, (2002) Role of genetic and epigenetic changes in Burkitt lymphoma. Semin Cancer Biol 12: 381-387.
    • (2002) Semin Cancer Biol , vol.12 , pp. 381-387
    • Lindstrom, M.S.1    Wiman, K.G.2
  • 37
    • 0035866785 scopus 로고    scopus 로고
    • Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine
    • Tafani M, Minchenko DA, Serroni A, Farber JL, (2001) Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine. Cancer Res 61: 2459-2466.
    • (2001) Cancer Res , vol.61 , pp. 2459-2466
    • Tafani, M.1    Minchenko, D.A.2    Serroni, A.3    Farber, J.L.4
  • 38
    • 0037053298 scopus 로고    scopus 로고
    • The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
    • Karpinich NO, Tafani M, Rothman RJ, Russo MA, Farber JL, (2002) The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J Biol Chem 277: 16547-16552.
    • (2002) J Biol Chem , vol.277 , pp. 16547-16552
    • Karpinich, N.O.1    Tafani, M.2    Rothman, R.J.3    Russo, M.A.4    Farber, J.L.5
  • 39
    • 14944348965 scopus 로고    scopus 로고
    • The role of BH3-only proteins in the immune system
    • Strasser A, (2005) The role of BH3-only proteins in the immune system. Nat Rev Immunol 5: 189-200.
    • (2005) Nat Rev Immunol , vol.5 , pp. 189-200
    • Strasser, A.1
  • 40
    • 77957938117 scopus 로고    scopus 로고
    • Viruses, microRNAs, and host interactions
    • Skalsky RL, Cullen BR, (2010) Viruses, microRNAs, and host interactions. Annu Rev Microbiol 64: 123-141.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 123-141
    • Skalsky, R.L.1    Cullen, B.R.2
  • 42
    • 0347382541 scopus 로고    scopus 로고
    • Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence
    • White RE, Calderwood MA, Whitehouse A, (2003) Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence. J Gen Virol 84: 3393-3403.
    • (2003) J Gen Virol , vol.84 , pp. 3393-3403
    • White, R.E.1    Calderwood, M.A.2    Whitehouse, A.3
  • 43
    • 0037069336 scopus 로고    scopus 로고
    • Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection
    • Neuhierl B, Feederle R, Hammerschmidt W, Delecluse HJ, (2002) Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection. Proc Natl Acad Sci U S A 99: 15036-15041.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15036-15041
    • Neuhierl, B.1    Feederle, R.2    Hammerschmidt, W.3    Delecluse, H.J.4
  • 44
    • 0034910721 scopus 로고    scopus 로고
    • Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C
    • Touitou R, Hickabottom M, Parker G, Crook T, Allday MJ, (2001) Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C. J Virol 75: 7749-7755.
    • (2001) J Virol , vol.75 , pp. 7749-7755
    • Touitou, R.1    Hickabottom, M.2    Parker, G.3    Crook, T.4    Allday, M.J.5
  • 45
    • 0023499869 scopus 로고
    • Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines
    • Finke J, Rowe M, Kallin B, Ernberg I, Rosen A, et al. (1987) Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines. J Virol 61: 3870-3878.
    • (1987) J Virol , vol.61 , pp. 3870-3878
    • Finke, J.1    Rowe, M.2    Kallin, B.3    Ernberg, I.4    Rosen, A.5
  • 46
    • 0035121381 scopus 로고    scopus 로고
    • Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death
    • Inman GJ, Binne UK, Parker GA, Farrell PJ, Allday MJ, (2001) Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death. J Virol 75: 2400-2410.
    • (2001) J Virol , vol.75 , pp. 2400-2410
    • Inman, G.J.1    Binne, U.K.2    Parker, G.A.3    Farrell, P.J.4    Allday, M.J.5
  • 47
    • 0025726282 scopus 로고
    • An Epstein-Barr virus-producer line Akata: establishment of the cell line and analysis of viral DNA
    • Takada K, Horinouchi K, Ono Y, Aya T, Osato T, et al. (1991) An Epstein-Barr virus-producer line Akata: establishment of the cell line and analysis of viral DNA. Virus Genes 5: 147-156.
    • (1991) Virus Genes , vol.5 , pp. 147-156
    • Takada, K.1    Horinouchi, K.2    Ono, Y.3    Aya, T.4    Osato, T.5


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