Wogonin suppresses TNF-α-induced MMP-9 expression by blocking the NF-κB activation via MAPK signaling pathways in human aortic smooth muscle cells

Biochemical and Biophysical Research Communications

Volumn 351, Issue 1, 2006, Pages 118-125

  Lee, Syng Ook ^a   Jeong, Yun Jeong ^a   Yu, Mi Hee ^a   Lee, Ji Won ^a   Hwangbo, Mi Hyang ^a   Kim, Cheorl Ho ^b   Lee, In Seon ^a  

^a Keimyung University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Migration; MMP 9; Scutellariae Radix; TNF ; Vascular smooth muscle cells; Wogonin

Indexed keywords

BAICALEIN; BAICALIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SCUTELLARIAE RADIX; TUMOR NECROSIS FACTOR ALPHA; WOGONIN;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

AORTA; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENZYME ACTIVATION; FLAVANONES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; TUMOR NECROSIS FACTOR-ALPHA;

SCUTELLARIA RADIX;

EID: 33750331488     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.10.006     Document Type: Article

References (43)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362 (1993) 801-809
2. Schwartz R.S., Holmes D.R., and Topol E.J. The restenosis paradigm revisited: an alternative proposal for cellular mechanisms. J. Am. Coll. Cardiol. 20 (1992) 1284-1293
3. Ip J.H., Fuster V., Israel D., Badimon L., Badimon J., and Chesebro J.H. The role of platelets, thrombin and hyperplasia in restenosis after coronary angioplasty. J. Am. Coll. Cardiol. 17 (1991) 77B-88B
4. Tipping P.G., and Hancock W.W. Production of tumor necrosis factor and interleukin-1 by macrophages from human atheromatous plaques. Am. J. Pathol. 142 (1993) 1721-1728
5. Jovinge S., Hultgardh-Nilsson A., Regnstrom J., and Nilsson J. Tumor necrosis factor-alpha activates smooth muscle cell migration in culture and is expressed in the balloon-injured rat aorta. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 490-497
6. Matrisian L.M. Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet. 6 (1990) 121-125
7. Sasaguri Y., Murahashi N., Sugama K., Kato S., Hiraoka K., Satoh T., Isomoto H., and Morimatsu M. Development-related changes in matrix metalloproteinase expression in human aortic smooth muscle cells. Lab. Invest. 71 (1994) 261-269
8. Dollery C.M., McEwan J.R., and Henny A.M. Matrix metalloproteinases and cardiovascular disease. Circ. Res. 77 (1995) 863-868
9. Galis Z.S., Johnson C., Godin D., Margid R., Shipley J.M., Senior R.M., and Ivan E. Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling. Circ. Res. 91 (2002) 852-859
10. Cho A., and Reidy M.A. Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury. Circ. Res. 91 (2002) 845-851
11. Cho A., Graves J., and Reidy M.A. Mitogen-activated protein kinases mediate matrix metalloproteinase-9 expression in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 2527-2532
12. Moon S.K., Cha B.Y., and Kim C.H. ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathway. J. Cell Physiol. 198 (2004) 417-427
13. Galis Z.S., Muszynski M., Sukhova G.K., Simon-Morrissey E., Unemori E.N., Lark W.W., Amento E., and Lebby P. Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion. Circ. Res. 75 (1994) 181-189
14. Moon S.K., Cho G.O., Jung S.Y., Gal S.W., Kwon T.K., Lee Y.C., Madamanchi N.R., and Kim C.H. Quercetin exerts multiple inhibitory effects on vascular smooth muscle cells: role of ERK1/2, cell-cycle regulation, and matrix metalloproteinase-9. Biochem. Biophys. Res. Commun. 301 (2003) 1069-1078
15. Chang H.M., and But P.P.H. Pharmacology and Applications of Chinese Material Medica vol. 2 (1987), World Scientific Publishing Co., Singapore pp. 1022-1027
16. Gao Z., Huang K., Yang X., and Xu H. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalenesis Georgi. Biochem. Biophys. Acta 1472 (1999) 643-650
17. Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. Pharmacol. Toxicol. 84 (1999) 288-291
18. Kitamura K., Honda M., Yoshizaki H., Yamamoto S., Nakane H., Fukushima M., Ono K., and Tokunaga T. Baicalin, an inhibitor of HIV-1 production in vitro. Antivir. Res. 37 (1998) 131-140
19. Lee H., Kim Y.O., Kim H., Kim S.Y., Noh H.S., Kang S.S., Cho G.J., Choi W.S., and Suk K. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J. 17 (2003) 1943-1944
20. Liu J.J., Huang T.S., Cheng W.F., and Lu F.J. Baicalein and baiclin are potent inhibitors of angiogenensis: Inhibition of endothelial cell proliferation, migration and differentiation. Int. J. Cancer 106 (2003) 559-565
21. Chang W.H., Chen C.H., and Lu F.J. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. Planta Med. 68 (2002) 128-132
22. Huang H.C., Wang H.R., and Hsieh L.M. Antiproliferative effect of baicalin, a flavonoid from a Chinese herb, on vascular smooth muscle cell. Eur. J. Pharmacol. 251 (1994) 91-93
23. Kimura Y., and Okuda H. Effects of flavonoids isolated from Scutellariae Radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells. J. Nat. Prod. 60 (1997) 598-601
24. You K.M., Jong H.G., and Kim H.P. Inhibition of cycolooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants. Arch. Pharm. Res. 22 (1999) 18-24
25. Chang Y.L., Shen J.J., Wung B.S., Cheng J.J., and Wang D.L. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Mol. Pharmacol. 60 (2001) 507-513
26. Eberhardt W., Huwiler A., Beck K.F., Walpen S., and Pfeilschifter J. Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated protein kinase pathways. J. Immunol. 165 (2000) 5788-5797
27. Zandi E., Chen Y., and Karin M. Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science 281 (1998) 1360-1363
28. Simon C., Simon M., Vucelic G., Hicks M.J., Plinkert P.K., Koitschev A., and Zenner H.P. The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. Exp. Cell Res. 271 (2001) 344-355
29. Shin M., Yan C., and Boyd D. An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression. Biochim. Biophys. Acta 1589 (2002) 311-316
30. Mason D.P., Kenagy R.D., Hasenstab D., Bowen-Pope D.F., Seifert R.A., Coats S., Hawkins S.M., and Clowes A.W. Matrix metalloproteinase-9 overexpression enhances vascular smooth muscle cell migration and alters remodeling in the injured rat carotid artery. Circ. Res. 85 (1999) 1179-1185
31. Newby A.C., and Zaltsman A.B. Molecular mechanisms in intimal hyperplasia. J. Pathol. 190 (2000) 300-309
32. Nakamura N., Hayasaka S., Zhang X.Y., Nagaki Y., Matsumoto M., Hayasaka Y., and Terasawa K. Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-κB binding activities induced by interleukin-1β in human retinal pigment epithelial cell line. Exp. Eye Res. 77 (2003) 195-202
33. Lai M.Y., Hsiu S.L., Chen C.C., Hou Y.C., and Chao P.D.L. Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of Scutellariae Radix in humans. Biol. Pharm. Bull. 26 (2003) 79-83
34. Sato H., and Seiki M. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8 (1993) 395-405
35. Gum R., Lengyel E., Juarez J., Chen J.H., Sato H., Seiki M., and Boyd D. Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J. Biol. Chem. 271 (1996) 10672-10680
36. Simon C., Goepfert H., and Boyd D. Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res. 58 (1998) 1135-1139
37. Genersch E., Hayess K., Neuenfeld Y., and Haller H. Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways. J. Cell Sci. 113 (2000) 4319-4330
38. McCawley L.J., O'Brien P., and Hudson L.G. Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)- mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9. J. Cell Physiol. 176 (1998) 255-265
39. Hong S., Park K.K., Magae J., Ando K., Lee T.S., Kwon T.K., Kwak J.Y., Kim C.H., and Chang Y.C. Ascochlorin inhibits matrix metalloproteinase-9 expression by suppressing activator protein-1-mediated gene expression through the ERK1/2 signaling pathway: inhibitory effects of ascochlorin on the invasion of renal carcinoma cells. J. Biol. Chem. 280 (2005) 25202-25209
40. Xie Z., Singh M., and Singh K. Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1β. J. Biol. Chem. 279 (2004) 39513-39519
41. Liu J.F., Crépin M., Liu J.M., Barritault D., and Ledoux D. FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway. Biochem. Biophys. Res. Commun. 293 (2002) 1174-1182
42. Hozumi A., Nshimura Y., Nishiuma T., Kotani Y., and Yokoyama M. Induction of MMP-9 in normal human bronchial epithelial cells by TNF-α via NF-κB-mediated pathway. Am. J. Physiol.-Lung C. 281 (2001) L1444-L1452
43. Tanimura Y., Kokuryo T., Tsunoda N., Yamazaki Y., Oda K., Nimura Y., Mon N.N., Huang P., Nakanuma Y., Chen M.F., Jan Y.Y., Yeh T.S., Chiu C.T., Hsieh L.L., and Hamaguchi M. Tumor necrosis factor α promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2. Cancer Lett. 219 (2005) 205-213