메뉴 건너뛰기




Volumn 104, Issue 4, 2007, Pages 355-365

Wogonin prevents glucocorticoid-induced thymocyte apoptosis without diminishing its anti-inflammatory action

Author keywords

Apoptosis; Flavone; Glucocorticoid; Thymus atrophy; Wogonin

Indexed keywords

BETAMETHASONE; CARRAGEENAN; DEXAMETHASONE; DNA FRAGMENT; HYDROCORTISONE; PHOSPHATIDYLSERINE; PREDNISOLONE; WOGONIN;

EID: 34548498411     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.FP0061501     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 4344700576 scopus 로고    scopus 로고
    • Glucocorticoid-induced apoptosis and glucocorticoid resistance: Molecular mechanisms and clinical relevance
    • Schmidt S, Rainer J, Ploner C, Presul E, Riml S, Kofler R. Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance. Cell Death Differ. 2004;11 Suppl 1:S45-S55.
    • (2004) Cell Death Differ , vol.11 , Issue.SUPPL. 1
    • Schmidt, S.1    Rainer, J.2    Ploner, C.3    Presul, E.4    Riml, S.5    Kofler, R.6
  • 2
    • 0034914405 scopus 로고    scopus 로고
    • A role for glucocorticoids in the thymus?
    • Jondal M, Pazirandeh A, Okret S. A role for glucocorticoids in the thymus? Trends Immunol. 2001;22:185-186.
    • (2001) Trends Immunol , vol.22 , pp. 185-186
    • Jondal, M.1    Pazirandeh, A.2    Okret, S.3
  • 4
    • 0034049874 scopus 로고    scopus 로고
    • Glucocorticoids in T cell development and function
    • Ashwell JD, Lu FW, Vacchio MS. Glucocorticoids in T cell development and function. Annu Rev Immunol. 2000;18:309-345.
    • (2000) Annu Rev Immunol , vol.18 , pp. 309-345
    • Ashwell, J.D.1    Lu, F.W.2    Vacchio, M.S.3
  • 5
    • 0032619951 scopus 로고    scopus 로고
    • Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia
    • Gaynon PS, Carrel AL. Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia. Adv Exp Med Biol. 1999;457:593-605.
    • (1999) Adv Exp Med Biol , vol.457 , pp. 593-605
    • Gaynon, P.S.1    Carrel, A.L.2
  • 6
    • 4644235617 scopus 로고    scopus 로고
    • Glucocorticoid receptors in human airways
    • Pujols L, Mullol J, Torrego A, Picado C. Glucocorticoid receptors in human airways. Allergy. 2004;59:1042-1052.
    • (2004) Allergy , vol.59 , pp. 1042-1052
    • Pujols, L.1    Mullol, J.2    Torrego, A.3    Picado, C.4
  • 7
    • 1842731968 scopus 로고    scopus 로고
    • Low-dose pulse methylprednisolone is an effective therapy for severe SLE flares
    • Kong KO, Badsha H, Lian TY, Edwards CJ, Chng HH. Low-dose pulse methylprednisolone is an effective therapy for severe SLE flares. Lupus. 2004;13:212-213.
    • (2004) Lupus , vol.13 , pp. 212-213
    • Kong, K.O.1    Badsha, H.2    Lian, T.Y.3    Edwards, C.J.4    Chng, H.H.5
  • 8
    • 3042833447 scopus 로고    scopus 로고
    • Overview of the actions of glucocorticoids on the immune response: A good model to characterize new pathways of immunosuppression for new treatment strategies
    • Franchimont D. Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies. Ann N Y Acad Sci. 2004;1024:124-137.
    • (2004) Ann N Y Acad Sci , vol.1024 , pp. 124-137
    • Franchimont, D.1
  • 9
    • 0344688183 scopus 로고    scopus 로고
    • Glucocorticoids and invasive fungal infections
    • Lionakis MS, Kontoyiannis DP. Glucocorticoids and invasive fungal infections. Lancet. 2003;362:1828-1838.
    • (2003) Lancet , vol.362 , pp. 1828-1838
    • Lionakis, M.S.1    Kontoyiannis, D.P.2
  • 10
    • 1542362487 scopus 로고    scopus 로고
    • Drug-induced pulmonary infection
    • White DA. Drug-induced pulmonary infection. Clin Chest Med. 2004;25:179-187.
    • (2004) Clin Chest Med , vol.25 , pp. 179-187
    • White, D.A.1
  • 11
    • 0033794615 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin
    • Shieh DE, Liu LT, Lin CC. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res. 2000;20:2861-2865.
    • (2000) Anticancer Res , vol.20 , pp. 2861-2865
    • Shieh, D.E.1    Liu, L.T.2    Lin, C.C.3
  • 12
    • 0035873932 scopus 로고    scopus 로고
    • Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells
    • Chi YS, Cheon BS, Kim HP. Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells. Biochem Pharmacol. 2001;61:1195-1203.
    • (2001) Biochem Pharmacol , vol.61 , pp. 1195-1203
    • Chi, Y.S.1    Cheon, B.S.2    Kim, H.P.3
  • 13
    • 1642553221 scopus 로고    scopus 로고
    • Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia
    • Lee H, Kim YO, Kim H, Kim SY, Noh HS, Kang SS, et al. Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. FASEB J. 2003;17:1943-1944.
    • (2003) FASEB J , vol.17 , pp. 1943-1944
    • Lee, H.1    Kim, Y.O.2    Kim, H.3    Kim, S.Y.4    Noh, H.S.5    Kang, S.S.6
  • 14
    • 2942604860 scopus 로고    scopus 로고
    • Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation
    • Son D, Lee P, Lee J, Kim H, Kim SY. Neuroprotective effect of wogonin in hippocampal slice culture exposed to oxygen and glucose deprivation. Eur J Pharmacol. 2004;493:99-102.
    • (2004) Eur J Pharmacol , vol.493 , pp. 99-102
    • Son, D.1    Lee, P.2    Lee, J.3    Kim, H.4    Kim, S.Y.5
  • 15
    • 21644489720 scopus 로고    scopus 로고
    • Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion
    • Cho J, Lee HK. Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. Biol Pharm Bull. 2004;27:1561-1564.
    • (2004) Biol Pharm Bull , vol.27 , pp. 1561-1564
    • Cho, J.1    Lee, H.K.2
  • 16
    • 16644397756 scopus 로고    scopus 로고
    • Neuroprotective effect of wogonin: Potential roles of inflammatory cytokines
    • Piao HZ, Jin SA, Chun HS, Lee JC, Kim WK. Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. Arch Pharm Res. 2004;27:930-936.
    • (2004) Arch Pharm Res , vol.27 , pp. 930-936
    • Piao, H.Z.1    Jin, S.A.2    Chun, H.S.3    Lee, J.C.4    Kim, W.K.5
  • 17
    • 0033022302 scopus 로고    scopus 로고
    • Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages
    • Wakabayashi I. Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages. Pharmacol Toxicol. 1999;84:288-291.
    • (1999) Pharmacol Toxicol , vol.84 , pp. 288-291
    • Wakabayashi, I.1
  • 18
    • 0032784239 scopus 로고    scopus 로고
    • The nitric oxide-producing activities of Scutellaria baicalensis
    • Kim HM, Moon EJ, Li E, Kim KM, Nam SY, Chung CK. The nitric oxide-producing activities of Scutellaria baicalensis. Toxicology. 1999;135:109-115.
    • (1999) Toxicology , vol.135 , pp. 109-115
    • Kim, H.M.1    Moon, E.J.2    Li, E.3    Kim, K.M.4    Nam, S.Y.5    Chung, C.K.6
  • 19
    • 0035371508 scopus 로고    scopus 로고
    • Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide
    • Chen YC, Shen SC, Chen LG, Lee TJ, Yang LL. Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide. Biochem Pharmacol. 2001;61:1417-1427.
    • (2001) Biochem Pharmacol , vol.61 , pp. 1417-1427
    • Chen, Y.C.1    Shen, S.C.2    Chen, L.G.3    Lee, T.J.4    Yang, L.L.5
  • 20
    • 0035839226 scopus 로고    scopus 로고
    • Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix
    • Park BK, Heo MY, Park H, Kim HP. Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix. Eur J Pharmacol. 2001;425:153-157.
    • (2001) Eur J Pharmacol , vol.425 , pp. 153-157
    • Park, B.K.1    Heo, M.Y.2    Park, H.3    Kim, H.P.4
  • 21
    • 1842504150 scopus 로고    scopus 로고
    • Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats
    • Park S, Hahm KB, Oh TY, Jin JH, Choue R. Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats. Dig Dis Sci. 2004;49:384-394.
    • (2004) Dig Dis Sci , vol.49 , pp. 384-394
    • Park, S.1    Hahm, K.B.2    Oh, T.Y.3    Jin, J.H.4    Choue, R.5
  • 22
    • 0035903037 scopus 로고    scopus 로고
    • The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production
    • Kim H, Kim YS, Kim SY, Suk K. The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. Neurosci Lett. 2001;309:67-71.
    • (2001) Neurosci Lett , vol.309 , pp. 67-71
    • Kim, H.1    Kim, Y.S.2    Kim, S.Y.3    Suk, K.4
  • 24
    • 0036016874 scopus 로고    scopus 로고
    • Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1
    • Chen YC, Shen SC, Lee WR, Lin HY, Ko CH, Shih CM, et al. Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1. Arch Toxicol. 2002;76:351-359.
    • (2002) Arch Toxicol , vol.76 , pp. 351-359
    • Chen, Y.C.1    Shen, S.C.2    Lee, W.R.3    Lin, H.Y.4    Ko, C.H.5    Shih, C.M.6
  • 25
    • 0027963466 scopus 로고
    • Selective inhibition of dexamethasone-induced apoptosis in rat thymocytes by herbimycin A
    • Lee E, Miura M, Yoshinari M, Iwai H, Kariya K. Selective inhibition of dexamethasone-induced apoptosis in rat thymocytes by herbimycin A. Biochem Biophys Res Commun. 1994;202:128-134.
    • (1994) Biochem Biophys Res Commun , vol.202 , pp. 128-134
    • Lee, E.1    Miura, M.2    Yoshinari, M.3    Iwai, H.4    Kariya, K.5
  • 26
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, van Oers MH. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 1994;84:1415-1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    van Oers, M.H.6
  • 27
    • 0029789429 scopus 로고    scopus 로고
    • A novel DNA cleaving agent, 2,2′-bis(2-aminoethyl)-4,4′-bithiazole, induces thymocyte apoptosis
    • Lee E, Miyaguchi F, Inoue M, Kariya K, Sasaki H. A novel DNA cleaving agent, 2,2′-bis(2-aminoethyl)-4,4′-bithiazole, induces thymocyte apoptosis. Biochem Mol Biol Int. 1996;40:151-157.
    • (1996) Biochem Mol Biol Int , vol.40 , pp. 151-157
    • Lee, E.1    Miyaguchi, F.2    Inoue, M.3    Kariya, K.4    Sasaki, H.5
  • 29
    • 0036581326 scopus 로고    scopus 로고
    • Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis
    • Pazirandeh A, Xue Y, Prestegaard T, Jondal M, Okret S. Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis. FASEB J. 2002;16:727-729.
    • (2002) FASEB J , vol.16 , pp. 727-729
    • Pazirandeh, A.1    Xue, Y.2    Prestegaard, T.3    Jondal, M.4    Okret, S.5
  • 30
    • 0034460335 scopus 로고    scopus 로고
    • Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock
    • Reichardt HM, Umland T, Bauer A, Kretz O, Schutz G. Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock. Mol Cell Biol. 2000;20:9009-9017.
    • (2000) Mol Cell Biol , vol.20 , pp. 9009-9017
    • Reichardt, H.M.1    Umland, T.2    Bauer, A.3    Kretz, O.4    Schutz, G.5
  • 32
    • 0037592259 scopus 로고    scopus 로고
    • Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis
    • Wang Z, Malone MH, He H, McColl KS, Distelhorst CW. Microarray analysis uncovers the induction of the proapoptotic BH3-only protein Bim in multiple models of glucocorticoid-induced apoptosis. J Biol Chem. 2003;278:23861-23867.
    • (2003) J Biol Chem , vol.278 , pp. 23861-23867
    • Wang, Z.1    Malone, M.H.2    He, H.3    McColl, K.S.4    Distelhorst, C.W.5
  • 33
    • 85047699977 scopus 로고    scopus 로고
    • Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays
    • Chauhan D, Auclair D, Robinson EK, Hideshima T, Li G, Podar K, et al. Identification of genes regulated by dexamethasone in multiple myeloma cells using oligonucleotide arrays. Oncogene. 2002;21:1346-1358.
    • (2002) Oncogene , vol.21 , pp. 1346-1358
    • Chauhan, D.1    Auclair, D.2    Robinson, E.K.3    Hideshima, T.4    Li, G.5    Podar, K.6
  • 34
    • 0030597111 scopus 로고    scopus 로고
    • Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis
    • Lee E, Furukubo T, Miyabe T, Yamauchi A, Kariya K. Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis. FEBS Lett. 1996;395:183-187.
    • (1996) FEBS Lett , vol.395 , pp. 183-187
    • Lee, E.1    Furukubo, T.2    Miyabe, T.3    Yamauchi, A.4    Kariya, K.5
  • 35
    • 4944228697 scopus 로고    scopus 로고
    • Flavonoids inhibit tumor necrosis factor-alpha-induced upregulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: Structure-activity relationships
    • Chen CC, Chow MP, Huang WC, Lin YC, Chang YJ. Flavonoids inhibit tumor necrosis factor-alpha-induced upregulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships. Mol Pharmacol. 2004;66:683-693.
    • (2004) Mol Pharmacol , vol.66 , pp. 683-693
    • Chen, C.C.1    Chow, M.P.2    Huang, W.C.3    Lin, Y.C.4    Chang, Y.J.5
  • 36
    • 0034876980 scopus 로고    scopus 로고
    • Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells
    • Chang YL, Shen JJ, Wung BS, Cheng JJ, Wang DL. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Mol Pharmacol. 2001;60:507-513.
    • (2001) Mol Pharmacol , vol.60 , pp. 507-513
    • Chang, Y.L.1    Shen, J.J.2    Wung, B.S.3    Cheng, J.J.4    Wang, D.L.5
  • 37
    • 0141517636 scopus 로고    scopus 로고
    • Quercetin protects the hydrogen peroxide-induced apoptosis via inhibition of mitochondrial dysfunction in H9c2 cardiomyoblast cells
    • Park C, So HS, Shin CH, Baek SH, Moon BS, Shin SH, et al. Quercetin protects the hydrogen peroxide-induced apoptosis via inhibition of mitochondrial dysfunction in H9c2 cardiomyoblast cells. Biochem Pharmacol. 2003;66:1287-1295.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1287-1295
    • Park, C.1    So, H.S.2    Shin, C.H.3    Baek, S.H.4    Moon, B.S.5    Shin, S.H.6
  • 39
    • 12244283706 scopus 로고    scopus 로고
    • Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten
    • Dok-Go H, Lee KH, Kim HJ, Lee EH, Lee J, Song YS, et al. Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten. Brain Res. 2003;965:130-136.
    • (2003) Brain Res , vol.965 , pp. 130-136
    • Dok-Go, H.1    Lee, K.H.2    Kim, H.J.3    Lee, E.H.4    Lee, J.5    Song, Y.S.6
  • 40
    • 0348251081 scopus 로고    scopus 로고
    • Quercetin attenuates oxygen-glucose deprivation- and excitotoxin-induced neurotoxicity in primary cortical cell cultures
    • Ha HJ, Kwon YS, Park SM, Shin T, Park JH, Kim HC, et al. Quercetin attenuates oxygen-glucose deprivation- and excitotoxin-induced neurotoxicity in primary cortical cell cultures. Biol Pharm Bull. 2003;26:544-546.
    • (2003) Biol Pharm Bull , vol.26 , pp. 544-546
    • Ha, H.J.1    Kwon, Y.S.2    Park, S.M.3    Shin, T.4    Park, J.H.5    Kim, H.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.