Catechols in caffeic acid phenethyl ester are essential for inhibition of TNF-mediated IP-10 expression through NF-κB-dependent but HO-1- and p38-independent mechanisms in mouse intestinal epithelial cells

Molecular Nutrition and Food Research

Volumn 55, Issue 12, 2011, Pages 1850-1861

  Mapesa, Job O ^a,b   Waldschmitt, Nadine ^a   Schmoeller, Ingrid ^a   Blume, Carolin ^a   Hofmann, Thomas ^a   Mahungu, Symon ^b   Clavel, Thomas ^a   Haller, Dirk ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b EGERTON UNIVERSITY   (Kenya)

Author keywords

Caffeic acid phenethyl ester; Inflammatory bowel diseases; Intestinal epithelium; Nuclear factor B; Polyphenols

Indexed keywords

CAFFEIC ACID DERIVATIVE; CAFFEIC ACID PHENETHYL ESTER; CATECHOL DERIVATIVE; CXCL10 PROTEIN, MOUSE; DRUG DERIVATIVE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEME OXYGENASE 1; HMOX1 PROTEIN, MOUSE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NFE2L2 PROTEIN, MOUSE; PHENETHYL ALCOHOL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; C57BL MOUSE; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; GENETICS; INTESTINE MUCOSA; METABOLISM; MOUSE; MOUSE MUTANT; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CAFFEIC ACIDS; CATECHOLS; CELL LINE; CHEMOKINE CXCL10; EPITHELIAL CELLS; HEME OXYGENASE-1; I-KAPPA B PROTEINS; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENYLETHYL ALCOHOL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 82955165806     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100105     Document Type: Article

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