MIP-2 secreted by epithelial cells increases neutrophil and lymphocyte recruitment in the mouse intestine

Gut

Volumn 49, Issue 4, 2001, Pages 526-533

  Ohtsuka, Y ^a,b   Lee, J ^b   Stamm, D S ^a,b   Sanderson, I R ^a,b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Chemokines; Epithelial cells; Intestinal mucosa; Leucocyte recruitment; Transgenic mouse

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR2; FATTY ACID BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; MYELOPEROXIDASE;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; IN VIVO STUDY; INTESTINE EPITHELIUM; LAMINA PROPRIA; LYMPHOCYTE TRANSFER; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; TRANSGENIC MOUSE;

ANIMALS; CHEMOKINES, CXC; CHEMOTAXIS, LEUKOCYTE; EPITHELIUM; IMMUNITY, CELLULAR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTESTINAL MUCOSA; LYMPHOCYTES; MICE; MICE, TRANSGENIC; MONOKINES; NEUTROPHIL INFILTRATION; PEROXIDASE; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAINING AND LABELING;

EID: 0034836370     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.49.4.526     Document Type: Article

References (33)

1. Mucosal barrier: An overview
2. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
3. Dietary regulation of genes expressed in the developing intestinal epithelium
4. Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes
5. Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin 8
6. Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium
7. Salmonella typhi stimulation of human intestinal epithelial cells induces secretion of epithelial cell-derived interleukin-6
8. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
9. Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro
10. Macrophage inflammatory protein-2: Chromosomal regulation in rat small intestinal epithelial cells
11. Butyrate enhances interleukin (IL)-8 secretion by intestinal epithelial cells in response to IL-1β and lipopolysaccharide
12. Highly polarized HLA class II antigen processing and presentation by human intestinal epithelial cells
13. Ontogeny of Ia messenger RNA in the mouse small intestinal epithelium is modulated by age of weaning and diet
14. Differential regulation of B7 mRNA in enterocytes and lymphoid cells
15. Intestinal interleukin-8 concentration and gene expression in inflammatory bowel disease
16. The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease
17. Identification and characterization of macrophage inflammatory protein 2
18. Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues
19. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties
20. Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its ceil lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium
21. The mouse intestinal fatty acid binding protein gene: Nucleotide sequence, pattern of developmental and regional expression, and proposed structure of its protein product
22. A 20-nucleotide element in the intestinal fatty acid binding protein gene modulates its cell lineage-specific, differentiation-dependent, and cephalocaudal patterns of expression in transgenic mice
23. SV40 T antigen transforms calcitonin cells of the thyroid but not CGRP-containing neurons in transgenic mice
24. Food antigen activates intraepithelial and lamina propria lymphocytes in food-sensitive enteropathy in mice
25. Oxygen free radical content and neutrophil infiltration are important determinants in mucosal injury after rat small bowel transplantation
26. New therapeutic possibility, of blocking cytokine-induced neutrophil chemoattractant on transient ischemic brain damage in rats
27. Intestinal intraepithelial lymphocytes have a promiscuous interleukin-8 receptor
28. α-quartz-induced chemokine expression by rat lung epithelial cells: Effect of in vivo and in vitro particle exposure
29. Measuring intraepithelial lymphocytes, surface area, and volume of lamina propria in the jejunal mucosa of coeliac patients
30. Small intestinal intraepithelial lymphocyte levels in cow's milk protein intolerance
31. Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo
32. Interferon-γ maintains the binding and functional capacity of receptors for IL-8 on cultured human T cells
33. Differentialand regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells