-
1
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel, K. M., Djuretic, I., Tanasa, B. and Rao, A. 2006. Regulation of Th2 differentiation and Il4 locus accessibility. Annu. Rev. Immunol. 24:607.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 607
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
4
-
-
77952313777
-
Differentiation of effector CD4 T cell populations
-
Zhu, J., Yamane, H. and Paul, W. E. 2010. Differentiation of effector CD4 T cell populations. Annu. Rev. Immunol. 28:445.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 445
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
5
-
-
1242276212
-
Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse
-
Sugimoto, T., Ishikawa, Y., Yoshimoto, T., Hayashi, N., Fujimoto, J. and Nakanishi, K. 2004. Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse. J. Exp. Med. 199:535.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 535
-
-
Sugimoto, T.1
Ishikawa, Y.2
Yoshimoto, T.3
Hayashi, N.4
Fujimoto, J.5
Nakanishi, K.6
-
6
-
-
10844230261
-
IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8
-
Hata, H., Yoshimoto, T., Hayashi, N., Hada, T. and Nakanishi, K. 2004. IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8. Int. Immunol. 16:1733.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1733
-
-
Hata, H.1
Yoshimoto, T.2
Hayashi, N.3
Hada, T.4
Nakanishi, K.5
-
7
-
-
35548946223
-
T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production
-
Hayashi, N., Yoshimoto, T., Izuhara, K., Matsui, K., Tanaka, T. and Nakanishi, K. 2007. T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-gamma and IL-13 production. Proc. Natl Acad. Sci. USA 104:14765.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 14765
-
-
Hayashi, N.1
Yoshimoto, T.2
Izuhara, K.3
Matsui, K.4
Tanaka, T.5
Nakanishi, K.6
-
8
-
-
33745026413
-
Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice
-
Terada, M., Tsutsui, H., Imai, Y. et al. 2006. Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice. Proc. Natl Acad. Sci. USA 103:8816.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8816
-
-
Terada, M.1
Tsutsui, H.2
Imai, Y.3
-
9
-
-
77954545021
-
Importance of IL-18-induced super Th1 cells for the development of allergic inflammation
-
Nakanishi, K., Tsutsui, H. and Yoshimoto, T. 2010. Importance of IL-18-induced super Th1 cells for the development of allergic inflammation. Allergol. Int. 59:137.
-
(2010)
Allergol. Int.
, vol.59
, pp. 137
-
-
Nakanishi, K.1
Tsutsui, H.2
Yoshimoto, T.3
-
10
-
-
77954302823
-
Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins
-
Kuroda-Morimoto, M., Tanaka, H., Hayashi, N. et al. 2010. Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins. Int. Immunol. 22:561.
-
(2010)
Int. Immunol.
, vol.22
, pp. 561
-
-
Kuroda-Morimoto, M.1
Tanaka, H.2
Hayashi, N.3
-
11
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
Zhou, L., Chong, M. M. and Littman, D. R. 2009. Plasticity of CD4+ T cell lineage differentiation. Immunity 30:646.
-
(2009)
Immunity
, vol.30
, pp. 646
-
-
Zhou, L.1
Chong, M.M.2
Littman, D.R.3
-
12
-
-
73849110167
-
Heterogeneity and plasticity of T helper cells
-
Zhu, J. and Paul, W. E. 2009. Heterogeneity and plasticity of T helper cells. Cell. Res 20:4.
-
(2009)
Cell. Res
, vol.20
, pp. 4
-
-
Zhu, J.1
Paul, W.E.2
-
13
-
-
77954948735
-
Effector T cell plasticity: flexibility in the face of changing circumstances
-
Murphy, K. M. and Stockinger, B. 2010. Effector T cell plasticity: flexibility in the face of changing circumstances. Nat. Immunol. 11:674.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 674
-
-
Murphy, K.M.1
Stockinger, B.2
-
14
-
-
77649220954
-
Mechanisms underlying lineage commitment and plasticity of helper CD4+ Tcells
-
O'Shea, J. J. and Paul, W. E. 2010. Mechanisms underlying lineage commitment and plasticity of helper CD4+ Tcells. Science 327:1098.
-
(2010)
Science
, vol.327
, pp. 1098
-
-
O'Shea, J.J.1
Paul, W.E.2
-
15
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee, Y. K., Turner, H., Maynard, C. L. et al. 2009. Late developmental plasticity in the T helper 17 lineage. Immunity 30:92.
-
(2009)
Immunity
, vol.30
, pp. 92
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
-
16
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove, G., Bouladoux, N., Wohlfert, E. A. et al. 2009. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 31:772.
-
(2009)
Immunity
, vol.31
, pp. 772
-
-
Oldenhove, G.1
Bouladoux, N.2
Wohlfert, E.A.3
-
17
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei, G., Wei, L., Zhu, J. et al. 2009. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 30:155.
-
(2009)
Immunity
, vol.30
, pp. 155
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
-
18
-
-
74549179138
-
Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)Tbet(+) cell subset with combined Th2 and Th1 cell functions
-
Hegazy, A. N., Peine, M., Helmstetter, C. et al. 2010. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)Tbet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 32:116.
-
(2010)
Immunity
, vol.32
, pp. 116
-
-
Hegazy, A.N.1
Peine, M.2
Helmstetter, C.3
-
19
-
-
0029876629
-
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
-
Kaplan, M. H., Schindler, U., Smiley, S. T. and Grusby, M. J. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4:313.
-
(1996)
Immunity
, vol.4
, pp. 313
-
-
Kaplan, M.H.1
Schindler, U.2
Smiley, S.T.3
Grusby, M.J.4
-
20
-
-
0035122901
-
Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene
-
Hu-Li, J., Pannetier, C., Guo, L. et al. 2001. Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity 14:1.
-
(2001)
Immunity
, vol.14
, pp. 1
-
-
Hu-Li, J.1
Pannetier, C.2
Guo, L.3
-
21
-
-
0032167664
-
Impaired development of Th2 cells in IL-13-deficient mice
-
McKenzie, G. J., Emson, C. L., Bell, S. E. et al. 1998. Impaired development of Th2 cells in IL-13-deficient mice. Immunity 9:423.
-
(1998)
Immunity
, vol.9
, pp. 423
-
-
McKenzie, G.J.1
Emson, C.L.2
Bell, S.E.3
-
22
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita, M., Ukai-Tadenuma, M., Kimura, M. et al. 2002. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J. Biol. Chem. 277:42399.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42399
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Kimura, M.3
-
23
-
-
78650304399
-
The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells
-
Tanaka, S., Motomura, Y., Suzuki, Y. et al. 2011. The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat. Immunol. 12:77.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 77
-
-
Tanaka, S.1
Motomura, Y.2
Suzuki, Y.3
-
24
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai, S. Y., Truitt, M. L. and Ho, I. C. 2004. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc. Natl Acad. Sci. USA 101:1993.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 1993
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
25
-
-
3042598052
-
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
-
Yamashita, M., Ukai-Tadenuma, M., Miyamoto, T. et al. 2004. Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J. Biol. Chem. 279:26983.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26983
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Miyamoto, T.3
-
26
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses
-
Zhu, J., Min, B., Hu-Li, J. et al. 2004. Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat. Immunol. 5:1157.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1157
-
-
Zhu, J.1
Min, B.2
Hu-Li, J.3
-
27
-
-
58849104422
-
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
-
Ho, I. C., Tai, T. S. and Pai, S. Y. 2009. GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat. Rev. Immunol. 9:125.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 125
-
-
Ho, I.C.1
Tai, T.S.2
Pai, S.Y.3
-
28
-
-
0032193770
-
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production
-
Yoshimoto, T., Takeda, K., Tanaka, T. et al. 1998. IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J. Immunol. 161:3400.
-
(1998)
J. Immunol.
, vol.161
, pp. 3400
-
-
Yoshimoto, T.1
Takeda, K.2
Tanaka, T.3
-
29
-
-
33744919804
-
IL-4 receptor alpha is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets
-
Andrews, A. L., Holloway, J. W., Holgate, S. T. and Davies, D. E. 2006. IL-4 receptor alpha is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets. J. Immunol. 176:7456.
-
(2006)
J. Immunol.
, vol.176
, pp. 7456
-
-
Andrews, A.L.1
Holloway, J.W.2
Holgate, S.T.3
Davies, D.E.4
-
30
-
-
15844404509
-
Essential role of Stat6 in IL-4 signalling
-
Takeda, K., Tanaka, T., Shi, W. et al. 1996. Essential role of Stat6 in IL-4 signalling. Nature 380:627.
-
(1996)
Nature
, vol.380
, pp. 627
-
-
Takeda, K.1
Tanaka, T.2
Shi, W.3
-
31
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang, W., Löhning, M., Gao, Z. et al. 2000. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 12:27.
-
(2000)
Immunity
, vol.12
, pp. 27
-
-
Ouyang, W.1
Löhning, M.2
Gao, Z.3
-
32
-
-
0035222187
-
A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation
-
Das, J., Chen, C. H., Yang, L., Cohn, L., Ray, P. and Ray, A. 2001. A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation. Nat. Immunol. 2:45.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 45
-
-
Das, J.1
Chen, C.H.2
Yang, L.3
Cohn, L.4
Ray, P.5
Ray, A.6
-
33
-
-
0031842614
-
Interaction of stat6 and NFkappaB: direct association and synergistic activation of interleukin-4-induced transcription
-
Shen, C. H. and Stavnezer, J. 1998. Interaction of stat6 and NFkappaB: direct association and synergistic activation of interleukin-4-induced transcription. Mol. Cell. Biol. 18:3395.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3395
-
-
Shen, C.H.1
Stavnezer, J.2
-
34
-
-
23844502969
-
Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway
-
Yamashita, M., Shinnakasu, R., Asou, H. et al. 2005. Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway. J. Biol. Chem. 280:29409.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29409
-
-
Yamashita, M.1
Shinnakasu, R.2
Asou, H.3
-
35
-
-
79954992071
-
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells
-
Motomura, Y., Kitamura, H., Hijikata, A. et al. 2011. The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat. Immunol. 12:450.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 450
-
-
Motomura, Y.1
Kitamura, H.2
Hijikata, A.3
-
36
-
-
12344308991
-
Deletion of a conserved Il4 silencer impairs T helper type1-mediated immunity
-
Ansel, K. M., Greenwald, R. J., Agarwal, S. et al. 2004. Deletion of a conserved Il4 silencer impairs T helper type1-mediated immunity. Nat. Immunol. 5:1251.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 1251
-
-
Ansel, K.M.1
Greenwald, R.J.2
Agarwal, S.3
-
37
-
-
33846489173
-
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
-
Djuretic, I. M., Levanon, D., Negreanu, V., Groner, Y., Rao, A. and Ansel, K. M. 2007. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat. Immunol. 8:145.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 145
-
-
Djuretic, I.M.1
Levanon, D.2
Negreanu, V.3
Groner, Y.4
Rao, A.5
Ansel, K.M.6
-
38
-
-
34250762587
-
Dynamic changes in histonemethylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells
-
Chang, S. and Aune, T. M. 2007. Dynamic changes in histonemethylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. Nat. Immunol. 8:723.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 723
-
-
Chang, S.1
Aune, T.M.2
-
39
-
-
0033598818
-
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils
-
Yoshimoto, T., Tsutsui, H., Tominaga, K. et al. 1999. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc. Natl Acad. Sci. USA 96:13962.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 13962
-
-
Yoshimoto, T.1
Tsutsui, H.2
Tominaga, K.3
-
40
-
-
67649229687
-
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity
-
Perrigoue, J. G., Saenz, S. A., Siracusa, M. C. et al. 2009. MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat. Immunol. 10:697.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 697
-
-
Perrigoue, J.G.1
Saenz, S.A.2
Siracusa, M.C.3
-
41
-
-
67649227119
-
Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells
-
Yoshimoto, T., Yasuda, K., Tanaka, H. et al. 2009. Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nat. Immunol. 10:706.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 706
-
-
Yoshimoto, T.1
Yasuda, K.2
Tanaka, H.3
-
42
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol, C. L., Chu, N. Q., Yu, S., Nish, S. A., Laufer, T. M. and Medzhitov, R. 2009. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat. Immunol. 10:713.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 713
-
-
Sokol, C.L.1
Chu, N.Q.2
Yu, S.3
Nish, S.A.4
Laufer, T.M.5
Medzhitov, R.6
-
43
-
-
0242516124
-
Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice
-
Yoshimoto, T., Min, B., Sugimoto, T. et al. 2003. Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice. J. Exp. Med. 197:997.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 997
-
-
Yoshimoto, T.1
Min, B.2
Sugimoto, T.3
-
44
-
-
33745634410
-
Contribution of IL-18-induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness
-
Ishikawa, Y., Yoshimoto, T. and Nakanishi, K. 2006. Contribution of IL-18-induced innate T cell activation to airway inflammation with mucus hypersecretion and airway hyperresponsiveness. Int. Immunol. 18:847.
-
(2006)
Int. Immunol.
, vol.18
, pp. 847
-
-
Ishikawa, Y.1
Yoshimoto, T.2
Nakanishi, K.3
|