Transmission-blocking activity of tafenoquine (WR-238605) and artelinic acid against naturally circulating strains of plasmodium vivax in Thailand

American Journal of Tropical Medicine and Hygiene

Volumn 69, Issue 5, 2003, Pages 542-547

  Ponsa, Narong ^a   Sattabongkot, Jetsumon ^b   Kittayapong, Pattamaporn ^a   Eikarat, Nantana ^b   Coleman, Russell E ^b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b U S ARMY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTELINIC ACID; DIHYDROACRIDINEDIONE; PRIMAQUINE; TAFENOQUINE; UNCLASSIFIED DRUG; WR 250547;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOPHELES; ANOPHELES DIRUS; ANTIMALARIAL ACTIVITY; ARTICLE; ARTIFICIAL MEMBRANE; BLOOD; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG ACTIVITY; DRUG SCREENING; FEEDING; GAMETOCYTE; HUMAN; HUMAN CELL; IMMUNOPROPHYLAXIS; INFECTION CONTROL; INFECTION PREVENTION; LABORATORY; MALARIA; MOUSE; NONHUMAN; OOCYST; OUTPATIENT DEPARTMENT; PARASITE DEVELOPMENT; PARASITE ISOLATION; PLASMODIUM VIVAX; SPOROZOITE; THAILAND;

ANIMALIA; ANOPHELES DIRUS; PLASMODIUM VIVAX; PROTOZOA;

EID: 1342304320     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2003.69.542     Document Type: Article

References (32)

1. World Health Organization, 1987. The Biology of Malaria Parasites. Report of a WHO Scientific Group. World Health Organ Tech Rep Ser 743. Geneva.
2. Gilles HM, Warrell DA, 1993. Bruce-Chwatt's Essential Malariology. Third edition. London: Edward Arnold, 164-195.
3. Oaks SC, Mitchell VS, Pearson GW, Carpenter CCJ, 1991. Malaria: Obstacles and Opportunities. Washington: National Academy Press.
4. Coleman RE, Ponsa N, Eikarat N, Kollars TM Jr, Sattabongkot J, 2001. Prevention of sporogony of Plasmodium vivax in Anopheles dirus mosquitoes by transmission-blocking antimalarials. Am J Trop Med Hyg 65: 214-218.
5. Coleman RE, Nath AK, Schneider I, Song G-H, Klein TA, Milhous WK, 1994. Transmission-blocking antimalarials prevent sporogony of Plasmodium falciparum and P. berghei in Anopheles stephensi mosquitoes. Am J Trop Med Hyg 50: 646-653.
6. Coleman RE, Clavin AM, Milhous WK, 1992. Gametocytocidal and sporontocidal activity of antimalarials against Plasmodium berghei ANKA in ICR mice and Anopheles stephensi mosquitoes. Am J Trop Med Hyg 46: 169-182.
7. Coleman RE, 1990. Sporontocidal activity of the antimalarial WR-238605 against Plasmodium berghei ANKA in Anopheles stephensi. Am J Trop Med Hyg 42: 196-205.
8. Butcher GA, 1997. Antimalarial drugs and the mosquito transmission of Plasmodium. Int J Parasitol 27: 975-987.
9. Teklehaimanot A, Nguyen-Dinh P, Collins WE, Barber AM, Campbell CC, 1985. Evaluation of sporontocidal compounds using Plasmodium falciparum gametocytes produced in vitro. Am J Trop Med Hyg 34: 429-434.
10. Coleman RE, Maneechai N, Yim-Amnuaychok N, Kumpitak C, Soyseng V, Miller RS, Thimasarn K, Sattabongkot J, 2002. Field evaluation of the ICT malaria Pf/ Pv immunochromatographic test for the detection of asymptomatic malaria in a Plasmodium falciparum/vivax endemic area in Thailand. Am J Trop Med Hyg 66: 379-383.
11. Young MD, 1959. The effect of small doses of primaquine upon malaria infections. Indian J Malariol 13: 69-74.
12. Brueckner RP, Lasseter KC, Lin ET, Schuster BG, 1998. First-time-in-humans safety and pharmacokinetics of WR 238605, a new antimalarial. Am J Trop Med Hyg 58: 645-649.
13. Milhous WK, 2001. Development of new drugs for chemoprophylaxis of malaria. Med Trop (Mars) 61: 48-50.
14. Peters W. 1999. The evolution of tafenoquine-antimalarial for a new millennium? J R Soc Med 92: 345-352.
15. Brueckner RP, Coster T, Wesche DL, Shmuklarsky M, Schuster BG, 1998. Prophylaxis of Plasmodium falciparum infection in a human challenge model with WR 238605, a new 8-aminoquinoline antimalarial. Antimicrob Agents Chemother 42: 1293-1294.
16. Lell B, Faucher JF, Missinou MA, Borrmann S, Dangelmaier O, Horton J, Kremsner PG, 2000. Malaria chemoprophylaxis with tafenoquine: a randomised study. Lancet 355: 2041-2045.
17. Edstein MD, Walsh DS, Eamsila C, Sasiprapha T, Nasveld PE, Kitchener S, Rieckmann KH, 2001. Malaria prophylaxis/radical cure: recent experiences of the Australian Defence Force. Med Trop (Mars) 61: 56-58.
18. Cooper RD, Milhous WK, Rieckmann KH, 1994. The efficacy of WR 238605 against the blood stages of a chloroquine resistant strain of Plasmodium vivax. Trans R Soc Trop Med Hyg 88: 691-692.
19. Peters W, Robinson BL, Milhous WK, 1993. The chemotherapy of rodent malaria. LI. Studies on a new 8-aminoquinoline, WR 238,605. Ann Trop Med Parasitol 87: 547-552.
20. Obaldia N III, Rossan RN, Cooper RD, Kyle DE, Nuzum EO, Rieckmann KH, Shanks GD, 1997. WR 238605, chloroquine, and their combinations as blood schizonticides against a chloroquine-resistant strain of Plasmodium vivax in Aotus monkeys. Am J Trop Med Hyg 56: 508-510.
21. Tripathi R, Puri SK, Dutta GP, 1996. Sodium β-artelinate-A new potential gametocytocide. Exp Parasitol 82: 251-254.
22. Mehra N, Bhasin VK, 1993. In vitro gametocytocidal activity of artemesinin and its derivatives on Plasmodium falciparum. Jpn J Med Sci Biol 46: 37-43.
23. Chen PQ, Li GQ, Guo XB, He KR, Fu YX, Fu LC, Song YZ, 1994. The infectivity of gametocytes of Plasmodium falciparum from patients treated with artemisinin. Chin Med J 107: 709-711.
24. Price RN, 2000. Artemisinin drugs: novel antimalarial agents. Expert Opin Investig Drugs 9: 1815-1827.
25. Labbe AC, Loutfy MR, Kain KC, 2001. Recent advances in the prophylaxis and treatment of Malaria. Curr Infect Dis Rep 3: 68-76.
26. Lopez-Antunano FJ, 1999. Is primaquine useful and safe as true exo-erythrocytic merontocidal, hypnozoitocidal and gametocidal antimalarial drug? Salud Publica Mex 41: 410-419.
27. Thimasarn K, 1992. Current measures of containment of multidrug resistant falciparum malaria in Thailand. Southeast Asian J Trop Med Public Health 23 (Suppl 4): 139-142.
28. Jong EC, Nothdurft HD, 2001. Current drugs for antimalarial chemoprophylaxis: a review of efficacy and safety. J Travel Med 8 (Suppl 3): S48-S56.
29. Shanks GD, Kain KC, Keystone JS, 2001. Malaria chemoprophylaxis in the age of drug resistance. II. Drugs that may be available in the future. Clin Infect Dis 33: 381-385.
30. Kain KC, Shanks GD, Keystone JS, 2001. Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. Clin Infect Dis 33: 226-234.
31. Li QG, Peggins JO, Lin AJ, Masonic KJ, Trotman KM, Brewer TG, 1998. Pharmacology and toxicology of artelinic acid: preclinical investigations on pharmacokinetics, metabolism, protein and red blood cell binding, and acute and anorectic toxicities. Trans R Soc Trop Med Hyg 92: 332-340.
32. Institute of Medicine, 1991. Malaria: Obstacles and Opportunities. Oaks SC, Mitchell VS, Pearson GW, Carpenter CCJ, eds. Washington, DC: National Academy Press.