Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms

Journal of Biological Chemistry

Volumn 286, Issue 49, 2011, Pages 42082-42090

  Colbert, Jeff D ^a,c   Matthews, Stephen P ^a   Kos, Janko ^b   Watts, Colin ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED MACROPHAGES; CATHEPSIN L; CELLULAR COMPARTMENTS; CYSTATINS; CYSTEINE PROTEASE; HARMFUL EFFECTS; IMMUNE CELLS; INHIBITORY ACTIVITY; PROTEASE INHIBITOR; WILD TYPES;

AMINO ACIDS;

MACROPHAGES;

CATHEPSIN L; CYSTATIN; CYSTATIN F; CYSTEINE PROTEINASE; GAMMA INTERFERON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; COMPLEX FORMATION; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STABILITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; ASPARAGINE; BONE MARROW CELLS; CATHEPSIN L; CYSTATIN C; CYSTATINS; DENDRITIC CELLS; ENDOCYTOSIS; ENDOPEPTIDASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KINETICS; LYSOSOMES; MACROPHAGES; MICE; MICE, INBRED C57BL; PEPTIDE HYDROLASES; SPLEEN;

EID: 82755195248     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.253914     Document Type: Article

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