-
1
-
-
78650530898
-
Pancreatic beta-cell K(ATP) channels: Hypoglycaemia and hyperglycaemia
-
Bennett K, James C, Hussain K, (2010) Pancreatic beta-cell K(ATP) channels: Hypoglycaemia and hyperglycaemia. Rev Endocr Metab Disord 11: 157-163.
-
(2010)
Rev Endocr Metab Disord
, vol.11
, pp. 157-163
-
-
Bennett, K.1
James, C.2
Hussain, K.3
-
2
-
-
0031773333
-
Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians
-
Hani EH, Boutin P, Durand E, Inoue H, Permutt MA, et al. (1998) Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia 41: 1511-1515.
-
(1998)
Diabetologia
, vol.41
, pp. 1511-1515
-
-
Hani, E.H.1
Boutin, P.2
Durand, E.3
Inoue, H.4
Permutt, M.A.5
-
3
-
-
0037317981
-
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52: 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
-
4
-
-
77955411524
-
Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians
-
Chauhan G, Spurgeon CJ, Tabassum R, Bhaskar S, Kulkarni SR, et al. (2010) Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians. Diabetes 59: 2068-2074.
-
(2010)
Diabetes
, vol.59
, pp. 2068-2074
-
-
Chauhan, G.1
Spurgeon, C.J.2
Tabassum, R.3
Bhaskar, S.4
Kulkarni, S.R.5
-
5
-
-
70449433016
-
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population
-
Hu C, Zhang R, Wang C, Wang J, Ma X, et al. (2009) PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS ONE 4: e7643.
-
(2009)
PLoS ONE
, vol.4
-
-
Hu, C.1
Zhang, R.2
Wang, C.3
Wang, J.4
Ma, X.5
-
6
-
-
68449086849
-
The E23K variation in the KCNJ11 gene is associated with type 2 diabetes in Chinese and East Asian population
-
Zhou D, Zhang D, Liu Y, Zhao T, Chen Z, et al. (2009) The E23K variation in the KCNJ11 gene is associated with type 2 diabetes in Chinese and East Asian population. J Hum Genet 54: 433-435.
-
(2009)
J Hum Genet
, vol.54
, pp. 433-435
-
-
Zhou, D.1
Zhang, D.2
Liu, Y.3
Zhao, T.4
Chen, Z.5
-
7
-
-
0036314298
-
K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels
-
Schwanstecher C, Meyer U, Schwanstecher M, (2002) K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels. Diabetes 51: 875-879.
-
(2002)
Diabetes
, vol.51
, pp. 875-879
-
-
Schwanstecher, C.1
Meyer, U.2
Schwanstecher, M.3
-
8
-
-
38149127196
-
KCNJ11 E23K affects diabetes risk and is associated with the disposition index: results of two independent German cohorts
-
Fischer A, Fisher E, Mohlig M, Schulze M, Hoffmann K, et al. (2008) KCNJ11 E23K affects diabetes risk and is associated with the disposition index: results of two independent German cohorts. Diabetes Care 31: 87-89.
-
(2008)
Diabetes Care
, vol.31
, pp. 87-89
-
-
Fischer, A.1
Fisher, E.2
Mohlig, M.3
Schulze, M.4
Hoffmann, K.5
-
9
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, et al. (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 42: 579-589.
-
(2010)
Nat Genet
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
Morris, A.P.4
Dina, C.5
-
10
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
-
11
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316: 1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
-
12
-
-
35748940314
-
Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study
-
Doi Y, Kubo M, Ninomiya T, Yonemoto K, Iwase M, et al. (2007) Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study. Diabetes 56: 2829-2833.
-
(2007)
Diabetes
, vol.56
, pp. 2829-2833
-
-
Doi, Y.1
Kubo, M.2
Ninomiya, T.3
Yonemoto, K.4
Iwase, M.5
-
13
-
-
38449118682
-
Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study
-
Vaxillaire M, Veslot J, Dina C, Proenca C, Cauchi S, et al. (2008) Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study. Diabetes 57: 244-254.
-
(2008)
Diabetes
, vol.57
, pp. 244-254
-
-
Vaxillaire, M.1
Veslot, J.2
Dina, C.3
Proenca, C.4
Cauchi, S.5
-
14
-
-
35448944056
-
Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women
-
Qi L, van Dam RM, Asselbergs FW, Hu FB, (2007) Gene-gene interactions between HNF4A and KCNJ11 in predicting Type 2 diabetes in women. Diabet Med 24: 1187-1191.
-
(2007)
Diabet Med
, vol.24
, pp. 1187-1191
-
-
Qi, L.1
van Dam, R.M.2
Asselbergs, F.W.3
Hu, F.B.4
-
15
-
-
33847041796
-
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program
-
Florez JC, Jablonski KA, Kahn SE, Franks PW, Dabelea D, et al. (2007) Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program. Diabetes 56: 531-536.
-
(2007)
Diabetes
, vol.56
, pp. 531-536
-
-
Florez, J.C.1
Jablonski, K.A.2
Kahn, S.E.3
Franks, P.W.4
Dabelea, D.5
-
16
-
-
10344246071
-
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes
-
Laukkanen O, Pihlajamaki J, Lindstrom J, Eriksson J, Valle TT, et al. (2004) Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 89: 6286-6290.
-
(2004)
The Finnish Diabetes Prevention Study. J Clin Endocrinol Metab
, vol.89
, pp. 6286-6290
-
-
Laukkanen, O.1
Pihlajamaki, J.2
Lindstrom, J.3
Eriksson, J.4
Valle, T.T.5
-
17
-
-
78649526616
-
Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies
-
Xu M, Bi Y, Xu Y, Yu B, Huang Y, et al. (2010) Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies. PLoS ONE 5: e14022.
-
(2010)
PLoS ONE
, vol.5
-
-
Xu, M.1
Bi, Y.2
Xu, Y.3
Yu, B.4
Huang, Y.5
-
18
-
-
0030844140
-
Epidemiology of cardiovascular risk factors in Hong Kong
-
Janus ED, (1997) Epidemiology of cardiovascular risk factors in Hong Kong. Clin Exp Pharmacol Physiol 24: 987-988.
-
(1997)
Clin Exp Pharmacol Physiol
, vol.24
, pp. 987-988
-
-
Janus, E.D.1
-
19
-
-
34249893904
-
Development of diabetes in Chinese with the metabolic syndrome: a 6-year prospective study
-
Cheung BM, Wat NM, Man YB, Tam S, Thomas GN, et al. (2007) Development of diabetes in Chinese with the metabolic syndrome: a 6-year prospective study. Diabetes Care 30: 1430-1436.
-
(2007)
Diabetes Care
, vol.30
, pp. 1430-1436
-
-
Cheung, B.M.1
Wat, N.M.2
Man, Y.B.3
Tam, S.4
Thomas, G.N.5
-
20
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ, (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15: 539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
21
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
-
22
-
-
29644438528
-
Genetic prediction of future type 2 diabetes
-
Lyssenko V, Almgren P, Anevski D, Orho-Melander M, Sjogren M, et al. (2005) Genetic prediction of future type 2 diabetes. PLoS Med 2: e345.
-
(2005)
PLoS Med
, vol.2
-
-
Lyssenko, V.1
Almgren, P.2
Anevski, D.3
Orho-Melander, M.4
Sjogren, M.5
-
23
-
-
58149333712
-
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study
-
van Hoek M, Dehghan A, Witteman JC, van Duijn CM, Uitterlinden AG, et al. (2008) Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes 57: 3122-3128.
-
(2008)
Diabetes
, vol.57
, pp. 3122-3128
-
-
van Hoek, M.1
Dehghan, A.2
Witteman, J.C.3
van Duijn, C.M.4
Uitterlinden, A.G.5
-
24
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C, Bogardus C, Mott DM, Pratley RE, (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104: 787-794.
-
(1999)
J Clin Invest
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
25
-
-
59449083573
-
Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes
-
Chistiakov DA, Potapov VA, Khodirev DC, Shamkhalova MS, Shestakova MV, et al. (2009) Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes. Acta Diabetol 46: 43-49.
-
(2009)
Acta Diabetol
, vol.46
, pp. 43-49
-
-
Chistiakov, D.A.1
Potapov, V.A.2
Khodirev, D.C.3
Shamkhalova, M.S.4
Shestakova, M.V.5
-
26
-
-
33846608291
-
Polymorphisms of KCNJ11 (Kir6.2 gene) are associated with Type 2 diabetes and hypertension in the Korean population
-
Koo BK, Cho YM, Park BL, Cheong HS, Shin HD, et al. (2007) Polymorphisms of KCNJ11 (Kir6.2 gene) are associated with Type 2 diabetes and hypertension in the Korean population. Diabet Med 24: 178-186.
-
(2007)
Diabet Med
, vol.24
, pp. 178-186
-
-
Koo, B.K.1
Cho, Y.M.2
Park, B.L.3
Cheong, H.S.4
Shin, H.D.5
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