Atrazine induces transcriptional changes in marker genes associated with steroidogenesis in primary cultures of rat Leydig cells

Toxicology in Vitro

Volumn 25, Issue 8, 2011, Pages 1588-1595

  Abarikwu, S O ^a   Farombi, E O ^b   Kashyap, M P ^c   Pant, A B ^c  

^a REDEEMER S UNIVERSITY   (Nigeria)

^b UNIVERSITY OF IBADAN   (Nigeria)

^c CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Atrazine; Interstitial Leydig cells; Primary cultures; Steroidogenic genes

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ATRAZINE; BROMINE DERIVATIVE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); DIMETHYLTHIAZOLDIPHENYLTETRAZOLIUM BROMIDE SALT; MESSENGER RNA; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; LEYDIG CELL; MARKER GENE; MTT ASSAY; NEUTRAL RED UPTAKE ASSAY; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; STEROIDOGENESIS;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ATRAZINE; CELL SURVIVAL; CELLS, CULTURED; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; COLORING AGENTS; ESTROGEN RECEPTOR ALPHA; GENE EXPRESSION REGULATION; HERBICIDES; INSULIN; LEYDIG CELLS; MALE; NEUTRAL RED; PHOSPHOPROTEINS; PROTEINS; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; THIAZOLES;

MAMMALIA; RATTUS;

EID: 82655173991     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.06.002     Document Type: Article

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