DNA arrays to monitor gene expression in rat blood and uterus following 17β-estradiol exposure: Biomonitoring environmental effects using surrogate tissues

Toxicological Sciences

Volumn 69, Issue 1, 2002, Pages 49-59

  Rockett, John C ^a,b   Kavlock, Robert J ^a   Lambright, Christy R ^a   Parks, Louise G ^a   Schmid, Judith E ^a   Wilson, Vickie S ^a   Wood, Carmen ^a   Dix, David J ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Biomonitoring; Blood; Endocrine disrupting chemical; Estradiol; Gene expression; Microarray; Rat; Surrogate tissue; Uterus

Indexed keywords

CORN OIL; DNA; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; PHOSPHOLIPASE A2; RNA; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; BLOOD ANALYSIS; CONTROLLED STUDY; DNA MICROARRAY; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE MUTATION; LEUKOCYTE; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARIECTOMY; PILOT STUDY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA HYBRIDIZATION; TARGET ORGAN; TISSUE SPECIFICITY; UTERUS;

ANIMALS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL MONITORING; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OVARIECTOMY; PILOT PROJECTS; RADIOIMMUNOASSAY; RATS; RATS, LONG-EVANS; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; UTERUS;

ANIMALIA; MAMMALIA; ZEA MAYS;

EID: 0036738643     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/69.1.49     Document Type: Article

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