Atrazine oral exposure of peripubertal male rats downregulates steroidogenesis gene expression in leydig cells

Toxicological Sciences

Volumn 111, Issue 1, 2009, Pages 189-197

  Pogrmic, Kristina ^a   Fa, Svetlana ^a   Dakic, Vanja ^a   Kaisarevic, Sonja ^a   Kovacevic, Radmila ^a  

^a UNIVERSITY OF NOVI SAD   (Serbia)

Author keywords

Atrazine; Gene expression; LC steroidogenesis

Indexed keywords

22 HYDROXYCHOLESTEROL; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROSTENEDIONE; ATRAZINE; CARRIER PROTEIN; CHORIONIC GONADOTROPIN; CYCLIC AMP; CYTOCHROME P450 17; CYTOCHROME P450 17A1; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; PHOSPHODIESTERASE; PHOSPHODIESTERASE 4B; PREGNENOLONE; PROGESTERONE; SCAVENGER RECEPTOR BI; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STEROIDOGENIC FACTOR 1; TESTOSTERONE 17BETA DEHYDROGENASE; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANDROGEN SYNTHESIS; ANDROGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EX VIVO STUDY; GENE EXPRESSION REGULATION; HORMONE INHIBITION; IN VIVO STUDY; LEYDIG CELL; MALE; NONHUMAN; ORGAN WEIGHT; PERIPUBERTY; PROSTATE VENTRAL LOBE; PUBERTY; RAT; RNA TRANSCRIPTION; SEMINAL VESICLE; STEROIDOGENESIS; TESTIS WEIGHT; WEIGHT REDUCTION;

ANDROGENS; ANIMALS; ATRAZINE; BODY WEIGHT; CELL SEPARATION; CHOLESTEROL; CYCLIC AMP; DOWN-REGULATION; HERBICIDES; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; ORGAN SIZE; PREGNENOLONE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SEXUAL MATURATION; STEROIDS;

ANIMALIA; RATTUS;

EID: 69049092777     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp135     Document Type: Article

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