Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice

International Journal of Neuropsychopharmacology

Volumn 14, Issue 5, 2011, Pages 711-717

  Omata, Naoto ^a,b   Chiu, Chi Tso ^a   Moya, Pablo R ^a   Leng, Yan ^a   Wang, Zhifei ^a   Hunsberger, Joshua G ^a   Leeds, Peter ^a   Chuang, De Maw ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

Antidepressant like effects; forced swim test; GSK 3 shRNA; hippocampal dentate gyrus; lentivirus

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; LENTIVIRUS VECTOR; SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC STRESS; CONTROLLED STUDY; DENTATE GYRUS; DEPRESSION; ENZYME ACTIVITY; GENE SILENCING; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; DENTATE GYRUS; DESIPRAMINE; GENETIC VECTORS; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HIPPOCAMPUS; HUMANS; LENTIVIRUS; MALE; MICE; MOTOR ACTIVITY; RNA, SMALL INTERFERING; STRESS, PHYSIOLOGICAL; SWIMMING;

EID: 79956041531     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145710000726     Document Type: Article

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