Fully human antibodies against the Protease-Activated Receptor-2 (PAR-2) with anti-inflammatory activity

Human Antibodies

Volumn 20, Issue 3-4, 2011, Pages 83-94

  Giblin, Patricia ^a   Boxhammer, Rainer ^b   Desai, Sudha ^a   Kroe Barrett, Rachel ^a   Hansen, Gale ^a   Ksiazek, John ^a   Panzenbeck, Maret ^a   Ralph, Kerry ^a   Schwartz, Racheline ^a   Zimmitti, Clare ^a   Pracht, Catrin ^b   Miller, Sandra ^b   Magram, Jeanne ^a,d   Litzenburger, Tobias ^a,c  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b MORPHOSYS AG   (Germany)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^d PFIZER INC   (United States)

Author keywords

antibody; inflammation; PAR 2

Indexed keywords

ANTIBODY; CALCIUM; CYTOKINE; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 2 ANTIBODY; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; RAT; SWELLING; VASCULAR RING; VASODILATATION;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, BLOCKING; AORTA; CALCIUM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; HEK293 CELLS; HUMANS; HYPERSENSITIVITY, DELAYED; INFLAMMATION; KINETICS; MACACA FASCICULARIS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PLASMIDS; RATS; RECEPTOR, PAR-2; TRANSFECTION; TRYPSIN;

EID: 82555187202     PISSN: 10932607     EISSN: 1875869X     Source Type: Journal    
DOI: 10.3233/HAB-2011-0243     Document Type: Article

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