Oligomerization propensity and flexibility of yeast frataxin studied by X-ray crystallography and small-angle X-ray scattering

Journal of Molecular Biology

Volumn 414, Issue 5, 2011, Pages 783-797

  Söderberg, Christopher A G ^a   Shkumatov, Alexander V ^b   Rajan, Sreekanth ^a   Gakh, Oleksandr ^c   Svergun, Dmitri I ^b   Isaya, Grazia ^c   Al Karadaghi, Salam ^a  

^a LUND UNIVERSITY   (Sweden)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c MAYO CLINIC   (United States)

Author keywords

Friedreich's ataxia; metal chaperone; neurodegenerative diseases; protein flexibility; protein oligomerization

Indexed keywords

ALANINE; CHEMICAL COMPOUND; COBALT; DIMER; FRATAXIN; GLYCEROL; HEXAMER; MONOMER; OLIGOMER; TRIMER; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; DIMERIZATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; X RAY CRYSTALLOGRAPHY; YEAST;

EID: 82555187015     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.10.034     Document Type: Article

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