메뉴 건너뛰기




Volumn 130, Issue 6, 2011, Pages 767-775

A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk

Author keywords

[No Author keywords available]

Indexed keywords

STEROID HORMONE;

EID: 82555174404     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-011-1025-6     Document Type: Article
Times cited : (30)

References (72)
  • 1
    • 0036911353 scopus 로고    scopus 로고
    • Interrogating a high-density SNP map for signitures of natural selection
    • DOI 10.1101/gr.631202
    • JM Akey G Zhang K Zhang L Jin MD Shriver 2002 Interrogating a high-density SNP map for signatures of natural selection Genome Res 12 1805 1814 10.1101/gr.631202 12466284 10.1101/gr.631202 1:CAS:528:DC%2BD38XpsVOqtbw%3D (Pubitemid 35469929)
    • (2002) Genome Research , vol.12 , Issue.12 , pp. 1805-1814
    • Akey, J.M.1    Zhang, G.2    Zhang, K.3    Jin, L.4    Shriver, M.D.5
  • 2
    • 34648847287 scopus 로고    scopus 로고
    • Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3)
    • DOI 10.1097/FPC.0b013e328256b198, PII 0121301120071000000004
    • CK Allerston M Shimizu M Fujieda EA Shephard H Yamazaki IR Phillips 2007 Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3) Pharmacogenet Genomics 17 827 839 10.1097/FPC.0b013e328256b198 17885620 10.1097/FPC.0b013e328256b198 1:CAS:528:DC%2BD2sXhtVKhsLfP (Pubitemid 47462296)
    • (2007) Pharmacogenetics and Genomics , vol.17 , Issue.10 , pp. 827-839
    • Allerston, C.K.1    Shimizu, M.2    Fujieda, M.3    Shephard, E.A.4    Yamazaki, H.5    Phillips, I.R.6
  • 6
    • 0032900678 scopus 로고    scopus 로고
    • Median-joining networks for inferring intraspecific phylogenies
    • HJ Bandelt P Forster A Rohl 1999 Median-joining networks for inferring intraspecific phylogenies Mol Biol Evol 16 37 48 10331250 1:CAS:528: DyaK1MXjvVGltA%3D%3D (Pubitemid 29024937)
    • (1999) Molecular Biology and Evolution , vol.16 , Issue.1 , pp. 37-48
    • Bandelt, H.-J.1    Forster, P.2    Rohl, A.3
  • 7
    • 0042858402 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme
    • DOI 10.1074/jbc.M305361200
    • O Barbier D Duran-Sandoval I Pineda-Torra V Kosykh JC Fruchart B Staels 2003 Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme J Biol Chem 278 32852 32860 10.1074/jbc.M305361200 12810707 10.1074/jbc. M305361200 1:CAS:528:DC%2BD3sXms1amurs%3D (Pubitemid 37055727)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.35 , pp. 32852-32860
    • Barbier, O.1    Duran-Sandoval, D.2    Pineda-Torra, I.3    Kosykh, V.4    Fruchart, J.-C.5    Staels, B.6
  • 8
    • 0038281429 scopus 로고    scopus 로고
    • FXR induces the UGT2B4 enzyme in hepatocytes: A potential mechanism of negative feedback control of FXR activity
    • DOI 10.1016/S0016-5085(03)00388-3
    • O Barbier IP Torra A Sirvent T Claudel C Blanquart D Duran-Sandoval F Kuipers V Kosykh JC Fruchart B Staels 2003 FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity Gastroenterology 124 1926 1940 10.1016/S0016-5085(03)00388-3 12806625 10.1016/S0016-5085(03)00388-3 1:CAS:528:DC%2BD3sXlt1yrtb8%3D (Pubitemid 36666787)
    • (2003) Gastroenterology , vol.124 , Issue.7 , pp. 1926-1940
    • Barbier, O.1    Torra, I.P.2    Sirvent, A.3    Claudel, T.4    Blanquart, C.5    Duran-Sandoval, D.6    Kuipers, F.7    Kosykh, V.8    Fruchart, J.-C.9    Staels, B.10
  • 9
    • 0345168229 scopus 로고    scopus 로고
    • Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans
    • DOI 10.1016/j.tem.2003.10.005
    • A Belanger G Pelletier F Labrie O Barbier S Chouinard 2003 Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans Trends Endocrinol Metab 14 473 479 10.1016/j.tem.2003.10.005 14643063 10.1016/j.tem.2003.10.005 1:CAS:528:DC%2BD3sXpt1Whs7o%3D (Pubitemid 37517349)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.10 , pp. 473-479
    • Belanger, A.1    Pelletier, G.2    Labrie, F.3    Barbier, O.4    Chouinard, S.5
  • 10
    • 33746237567 scopus 로고    scopus 로고
    • Genomic insights into positive selection
    • DOI 10.1016/j.tig.2006.06.005, PII S0168952506001739
    • S Biswas JM Akey 2006 Genomic insights into positive selection Trends Genet 22 437 446 10.1016/j.tig.2006.06.005 16808986 10.1016/j.tig.2006.06.005 1:CAS:528:DC%2BD28XntlCksbo%3D (Pubitemid 44093769)
    • (2006) Trends in Genetics , vol.22 , Issue.8 , pp. 437-446
    • Biswas, S.1    Akey, J.M.2
  • 11
    • 0030782193 scopus 로고    scopus 로고
    • Strong balancing selection at HLA loci: Evidence from segregation in South Amerindian families
    • DOI 10.1073/pnas.94.23.12452
    • FL Black PW Hedrick 1997 Strong balancing selection at HLA loci: evidence from segregation in South Amerindian families Proc Natl Acad Sci USA 94 12452 12456 9356470 10.1073/pnas.94.23.12452 1:CAS:528:DyaK2sXns1ylsbg%3D (Pubitemid 27492549)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.23 , pp. 12452-12456
    • Black, F.L.1    Hedrick, P.W.2
  • 13
    • 54149112918 scopus 로고    scopus 로고
    • The signature of long-standing balancing selection at the human defensin beta-1 promoter
    • 10.1186/gb-2008-9-9-r143 18817538 10.1186/gb-2008-9-9-r143
    • R Cagliani M Fumagalli S Riva U Pozzoli GP Comi G Menozzi N Bresolin M Sironi 2008 The signature of long-standing balancing selection at the human defensin beta-1 promoter Genome Biol 9 R143 10.1186/gb-2008-9-9-r143 18817538 10.1186/gb-2008-9-9-r143
    • (2008) Genome Biol , vol.9 , pp. 143
    • Cagliani, R.1    Fumagalli, M.2    Riva, S.3    Pozzoli, U.4    Comi, G.P.5    Menozzi, G.6    Bresolin, N.7    Sironi, M.8
  • 14
    • 75649146238 scopus 로고    scopus 로고
    • Genetic variability in the ACE gene region surrounding the Alu I/D polymorphism is maintained by balancing selection in human populations
    • 10.1097/FPC.0b013e3283333532 20038859 10.1097/FPC.0b013e3283333532 1:CAS:528:DC%2BC3cXnvFyrug%3D%3D
    • R Cagliani M Fumagalli S Riva U Pozzoli GP Comi N Bresolin M Sironi 2010 Genetic variability in the ACE gene region surrounding the Alu I/D polymorphism is maintained by balancing selection in human populations Pharmacogenet Genomics 20 131 134 10.1097/FPC.0b013e3283333532 20038859 10.1097/FPC.0b013e3283333532 1:CAS:528:DC%2BC3cXnvFyrug%3D%3D
    • (2010) Pharmacogenet Genomics , vol.20 , pp. 131-134
    • Cagliani, R.1    Fumagalli, M.2    Riva, S.3    Pozzoli, U.4    Comi, G.P.5    Bresolin, N.6    Sironi, M.7
  • 15
    • 78149277185 scopus 로고    scopus 로고
    • Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection
    • 10.1093/hmg/ddq401 20843824 10.1093/hmg/ddq401 1:CAS:528: DC%2BC3cXhtlyktr%2FJ
    • R Cagliani S Riva M Biasin M Fumagalli U Pozzoli S Lo Caputo F Mazzotta L Piacentini N Bresolin M Clerici M Sironi 2010 Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection Hum Mol Genet 19 4705 4714 10.1093/hmg/ddq401 20843824 10.1093/hmg/ddq401 1:CAS:528:DC%2BC3cXhtlyktr%2FJ
    • (2010) Hum Mol Genet , vol.19 , pp. 4705-4714
    • Cagliani, R.1    Riva, S.2    Biasin, M.3    Fumagalli, M.4    Pozzoli, U.5    Lo Caputo, S.6    Mazzotta, F.7    Piacentini, L.8    Bresolin, N.9    Clerici, M.10    Sironi, M.11
  • 16
    • 0346373654 scopus 로고    scopus 로고
    • Selecting a Maximally Informative Set of Single-Nucleotide Polymorphisms for Association Analyses Using Linkage Disequilibrium
    • DOI 10.1086/381000
    • CS Carlson MA Eberle MJ Rieder Q Yi L Kruglyak DA Nickerson 2004 Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium Am J Hum Genet 74 106 120 10.1086/381000 14681826 10.1086/381000 1:CAS:528:DC%2BD2cXlvVOrsA%3D%3D (Pubitemid 38085242)
    • (2004) American Journal of Human Genetics , vol.74 , Issue.1 , pp. 106-120
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Yi, Q.4    Kruglyak, L.5    Nickerson, D.A.6
  • 17
    • 0033573946 scopus 로고    scopus 로고
    • Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer
    • JA Cauley FL Lucas LH Kuller K Stone W Browner SR Cummings 1999 Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer Study of Osteoporotic Fractures Research Group Ann Intern Med 130 270 277 10068384 1:CAS:528:DyaK1MXhsleiu7w%3D (Pubitemid 29091854)
    • (1999) Annals of Internal Medicine , vol.130 , Issue.4 , pp. 270-277
    • Cauley, J.A.1    Lucas, F.L.2    Kuller, L.H.3    Stone, K.4    Browner, W.5    Cummings, S.R.6
  • 18
    • 0037370384 scopus 로고    scopus 로고
    • The application of molecular genetic approaches to the study of human evolution
    • DOI 10.1038/ng1113
    • Cavalli-Sforza LL, Feldman MW (2003) The application of molecular genetic approaches to the study of human evolution. Nat Genet 33 Suppl: 266-275. doi: 10.1038/ng1113 (Pubitemid 36284715)
    • (2003) Nature Genetics , vol.33 , Issue.SUPPL. , pp. 266-275
    • Cavalli-Sforza, L.L.1    Feldman, M.W.2
  • 19
    • 33646484211 scopus 로고    scopus 로고
    • Balancing selection and its effects on sequences in nearby genome regions
    • 10.1371/journal.pgen.0020064 16683038 10.1371/journal.pgen.0020064
    • D Charlesworth 2006 Balancing selection and its effects on sequences in nearby genome regions PLoS Genet 2 e64 10.1371/journal.pgen.0020064 16683038 10.1371/journal.pgen.0020064
    • (2006) PLoS Genet , vol.2 , pp. 64
    • Charlesworth, D.1
  • 21
    • 0041381056 scopus 로고    scopus 로고
    • UGT pharmacogenomics: Implications for cancer risk and cancer therapeutics
    • DOI 10.1097/00008571-200308000-00010
    • AA Desai F Innocenti MJ Ratain 2003 UGT pharmacogenomics: implications for cancer risk and cancer therapeutics Pharmacogenetics 13 517 523 10.1097/01.fpc.0000054116.14659.e5 12893990 10.1097/00008571-200308000-00010 1:CAS:528:DC%2BD3sXlvV2jtLw%3D (Pubitemid 37034594)
    • (2003) Pharmacogenetics , vol.13 , Issue.8 , pp. 517-523
    • Desai, A.A.1    Innocenti, F.2    Ratain, M.J.3
  • 22
    • 0030821992 scopus 로고    scopus 로고
    • Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection
    • 9335623 1:STN:280:DyaK2svns1egtQ%3D%3D
    • YX Fu 1997 Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection Genetics 147 915 925 9335623 1:STN:280:DyaK2svns1egtQ%3D%3D
    • (1997) Genetics , vol.147 , pp. 915-925
    • Fu, Y.X.1
  • 23
    • 0027453041 scopus 로고
    • Statistical tests of neutrality of mutations
    • 8454210 1:STN:280:DyaK3s3gt1Crsw%3D%3D
    • YX Fu WH Li 1993 Statistical tests of neutrality of mutations Genetics 133 693 709 8454210 1:STN:280:DyaK3s3gt1Crsw%3D%3D
    • (1993) Genetics , vol.133 , pp. 693-709
    • Fu, Y.X.1    Li, W.H.2
  • 24
    • 73849112043 scopus 로고    scopus 로고
    • A population genetics study of the familial Mediterranean fever gene: Evidence of balancing selection under an overdominance regime
    • 10.1038/gene.2009.59 19675583 10.1038/gene.2009.59 1:STN:280: DC%2BD1MjptlamsA%3D%3D
    • M Fumagalli R Cagliani U Pozzoli S Riva GP Comi G Menozzi N Bresolin M Sironi 2009 A population genetics study of the familial Mediterranean fever gene: evidence of balancing selection under an overdominance regime Genes Immun 10 678 686 10.1038/gene.2009.59 19675583 10.1038/gene.2009.59 1:STN:280:DC%2BD1MjptlamsA%3D%3D
    • (2009) Genes Immun , vol.10 , pp. 678-686
    • Fumagalli, M.1    Cagliani, R.2    Pozzoli, U.3    Riva, S.4    Comi, G.P.5    Menozzi, G.6    Bresolin, N.7    Sironi, M.8
  • 25
    • 59949095839 scopus 로고    scopus 로고
    • Widespread balancing selection and pathogen-driven selection at blood group antigen genes
    • 10.1101/gr.082768.108 18997004 10.1101/gr.082768.108 1:CAS:528: DC%2BD1MXhvVSjurc%3D
    • M Fumagalli R Cagliani U Pozzoli S Riva GP Comi G Menozzi N Bresolin M Sironi 2009 Widespread balancing selection and pathogen-driven selection at blood group antigen genes Genome Res 19 199 212 10.1101/gr.082768.108 18997004 10.1101/gr.082768.108 1:CAS:528:DC%2BD1MXhvVSjurc%3D
    • (2009) Genome Res , vol.19 , pp. 199-212
    • Fumagalli, M.1    Cagliani, R.2    Pozzoli, U.3    Riva, S.4    Comi, G.P.5    Menozzi, G.6    Bresolin, N.7    Sironi, M.8
  • 26
    • 67449110978 scopus 로고    scopus 로고
    • Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions
    • 10.1084/jem.20082779 19468064 10.1084/jem.20082779 1:CAS:528: DC%2BD1MXntFGlsrw%3D
    • M Fumagalli U Pozzoli R Cagliani GP Comi S Riva M Clerici N Bresolin M Sironi 2009 Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions J Exp Med 206 1395 1408 10.1084/jem.20082779 19468064 10.1084/jem.20082779 1:CAS:528: DC%2BD1MXntFGlsrw%3D
    • (2009) J Exp Med , vol.206 , pp. 1395-1408
    • Fumagalli, M.1    Pozzoli, U.2    Cagliani, R.3    Comi, G.P.4    Riva, S.5    Clerici, M.6    Bresolin, N.7    Sironi, M.8
  • 27
    • 47749111708 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and their role in regulating UDP glucurono-syltransferase gene expression
    • DOI 10.2174/138920008784746409
    • DA Gardner-Stephen PI Mackenzie 2008 Liver-enriched transcription factors and their role in regulating UDP glucuronosyltransferase gene expression Curr Drug Metab 9 439 452 18537579 10.2174/138920008784746409 1:CAS:528: DC%2BD1cXotF2ntLY%3D (Pubitemid 352025197)
    • (2008) Current Drug Metabolism , vol.9 , Issue.5 , pp. 439-452
    • Gardner-Stephen, D.A.1    Mackenzie, P.I.2
  • 28
    • 33845253388 scopus 로고    scopus 로고
    • Haplotype structure of FSHB, the beta-subunit gene for fertility-associated follicle-stimulating hormone: Possible influence of balancing selection
    • DOI 10.1111/j.1469-1809.2006.00299.x
    • M Grigorova K Rull M Laan 2007 Haplotype structure of FSHB, the beta-subunit gene for fertility-associated follicle-stimulating hormone: possible influence of balancing selection Ann Hum Genet 71 18 28 10.1111/j.1469-1809.2006.00299.x 17227474 10.1111/j.1469-1809.2006.00299.x 1:CAS:528:DC%2BD2sXitVCltrk%3D (Pubitemid 44857679)
    • (2007) Annals of Human Genetics , vol.71 , Issue.1 , pp. 18-28
    • Grigorova, M.1    Rull, K.2    Laan, M.3
  • 29
    • 0037819284 scopus 로고    scopus 로고
    • Pharmacogenomics of human UDP-glucuronosyltransferase enzymes
    • DOI 10.1038/sj.tpj.6500171
    • C Guillemette 2003 Pharmacogenomics of human UDP-glucuronosyltransferase enzymes Pharmacogenomics J 3 136 158 10.1038/sj.tpj.6500171 12815363 10.1038/sj.tpj.6500171 1:CAS:528:DC%2BD3sXks1Cnu7w%3D (Pubitemid 36850156)
    • (2003) Pharmacogenomics Journal , vol.3 , Issue.3 , pp. 136-158
    • Guillemette, C.1
  • 30
    • 7444258476 scopus 로고    scopus 로고
    • Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: An overview
    • DOI 10.1186/bcr936
    • C Guillemette A Belanger J Lepine 2004 Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview Breast Cancer Res 6 246 254 10.1186/bcr936 15535854 10.1186/bcr936 1:CAS:528:DC%2BD2cXpt1ajtrk%3D (Pubitemid 39440253)
    • (2004) Breast Cancer Research , vol.6 , Issue.6 , pp. 246-254
    • Guillemette, C.1    Belanger, A.2    Lepine, J.3
  • 31
    • 33645734407 scopus 로고    scopus 로고
    • Long-term persistence of both functional and non-functional alleles at the leukocyte immunoglobulin-like receptor A3 (LILRA3) locus suggests balancing selection
    • 10.1007/s00439-006-0152-y 16501917 10.1007/s00439-006-0152-y 1:CAS:528:DC%2BD28XjtlWns7g%3D
    • K Hirayasu J Ohashi K Kashiwase M Takanashi M Satake K Tokunaga T Yabe 2006 Long-term persistence of both functional and non-functional alleles at the leukocyte immunoglobulin-like receptor A3 (LILRA3) locus suggests balancing selection Hum Genet 119 436 443 10.1007/s00439-006-0152-y 16501917 10.1007/s00439-006-0152-y 1:CAS:528:DC%2BD28XjtlWns7g%3D
    • (2006) Hum Genet , vol.119 , pp. 436-443
    • Hirayasu, K.1    Ohashi, J.2    Kashiwase, K.3    Takanashi, M.4    Satake, M.5    Tokunaga, K.6    Yabe, T.7
  • 32
    • 43149115581 scopus 로고    scopus 로고
    • Directional and balancing selection in human beta-defensins
    • DOI 10.1186/1471-2148-8-113
    • EJ Hollox JA Armour 2008 Directional and balancing selection in human beta-defensins BMC Evol Biol 8 113 10.1186/1471-2148-8-113 18416833 10.1186/1471-2148-8-113 (Pubitemid 351643678)
    • (2008) BMC Evolutionary Biology , vol.8 , Issue.1 , pp. 113
    • Hollox, E.J.1    Armour, J.A.L.2
  • 33
    • 0036184745 scopus 로고    scopus 로고
    • Generating samples under a Wright-Fisher neutral model of genetic variation
    • RR Hudson 2002 Generating samples under a Wright-Fisher neutral model of genetic variation Bioinformatics 18 337 338 10.1093/bioinformatics/18.2.337 11847089 10.1093/bioinformatics/18.2.337 1:CAS:528:DC%2BD38XitFentrw%3D (Pubitemid 34183119)
    • (2002) Bioinformatics , vol.18 , Issue.2 , pp. 337-338
    • Hudson, R.R.1
  • 34
    • 67650821911 scopus 로고    scopus 로고
    • Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers
    • 10.1124/dmd.109.027227 19439486 10.1124/dmd.109.027227 1:CAS:528:DC%2BD1MXps1ygtLk%3D
    • T Izukawa M Nakajima R Fujiwara H Yamanaka T Fukami M Takamiya Y Aoki S Ikushiro T Sakaki T Yokoi 2009 Quantitative analysis of UDP- glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers Drug Metab Dispos 37 1759 1768 10.1124/dmd.109.027227 19439486 10.1124/dmd.109.027227 1:CAS:528:DC%2BD1MXps1ygtLk%3D
    • (2009) Drug Metab Dispos , vol.37 , pp. 1759-1768
    • Izukawa, T.1    Nakajima, M.2    Fujiwara, R.3    Yamanaka, H.4    Fukami, T.5    Takamiya, M.6    Aoki, Y.7    Ikushiro, S.8    Sakaki, T.9    Yokoi, T.10
  • 35
    • 32544455635 scopus 로고    scopus 로고
    • Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism
    • DOI 10.1210/jc.2005-1643
    • J Jakobsson L Ekstrom N Inotsume M Garle M Lorentzon C Ohlsson HK Roh K Carlstrom A Rane 2006 Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism J Clin Endocrinol Metab 91 687 693 10.1210/jc.2005-1643 16332934 10.1210/jc.2005-1643 1:CAS:528:DC%2BD28XhsFKmsrw%3D (Pubitemid 43236944)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.2 , pp. 687-693
    • Jakobsson, J.1    Ekstrom, L.2    Inotsume, N.3    Garle, M.4    Lorentzon, M.5    Ohlsson, C.6    Roh, H.-K.7    Carlstrom, K.8    Rane, A.9
  • 36
    • 62349110318 scopus 로고    scopus 로고
    • A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys
    • 10.1210/jc.2008-1984 19088161 10.1210/jc.2008-1984 1:CAS:528: DC%2BD1MXjt1WmtLw%3D
    • A Juul K Sorensen L Aksglaede I Garn E Rajpert-De Meyts I Hullstein P Hemmersbach AM Ottesen 2009 A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys J Clin Endocrinol Metab 94 1005 1011 10.1210/jc.2008-1984 19088161 10.1210/jc.2008-1984 1:CAS:528: DC%2BD1MXjt1WmtLw%3D
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1005-1011
    • Juul, A.1    Sorensen, K.2    Aksglaede, L.3    Garn, I.4    Rajpert-De Meyts, E.5    Hullstein, I.6    Hemmersbach, P.7    Ottesen, A.M.8
  • 37
    • 0033010997 scopus 로고    scopus 로고
    • Serum oestradiol and breast cancer risk
    • DOI 10.1677/erc.0.0060175
    • TJ Key 1999 Serum oestradiol and breast cancer risk Endocr Relat Cancer 6 175 180 10731106 10.1677/erc.0.0060175 1:CAS:528:DyaK1MXktVygtLs%3D (Pubitemid 29260049)
    • (1999) Endocrine-Related Cancer , vol.6 , Issue.2 , pp. 175-180
    • Key, T.J.1
  • 38
    • 0034278984 scopus 로고    scopus 로고
    • UDP-glucuronosyltransferases
    • 11465080 10.2174/1389200003339171 1:CAS:528:DC%2BD3cXntlOrs70%3D
    • CD King GR Rios MD Green TR Tephly 2000 UDP-glucuronosyltransferases Curr Drug Metab 1 143 161 11465080 10.2174/1389200003339171 1:CAS:528: DC%2BD3cXntlOrs70%3D
    • (2000) Curr Drug Metab , vol.1 , pp. 143-161
    • King, C.D.1    Rios, G.R.2    Green, M.D.3    Tephly, T.R.4
  • 39
    • 65649117685 scopus 로고    scopus 로고
    • DnaSP v5: A software for comprehensive analysis of DNA polymorphism data
    • 10.1093/bioinformatics/btp187 19346325 10.1093/bioinformatics/btp187 1:CAS:528:DC%2BD1MXmtFeqtr8%3D
    • P Librado J Rozas 2009 DnaSP v5: a software for comprehensive analysis of DNA polymorphism data Bioinformatics 25 1451 1452 10.1093/bioinformatics/btp187 19346325 10.1093/bioinformatics/btp187 1:CAS:528:DC%2BD1MXmtFeqtr8%3D
    • (2009) Bioinformatics , vol.25 , pp. 1451-1452
    • Librado, P.1    Rozas, J.2
  • 40
    • 33344455672 scopus 로고    scopus 로고
    • An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide
    • DOI 10.1086/500593
    • X Liu Y Fu Z Liu B Lin Y Xie Y Liu Y Xu J Lin X Fan M Dong K Zeng CI Wu A Xu 2006 An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide Am J Hum Genet 78 393 400 10.1086/500593 16465617 10.1086/500593 1:CAS:528:DC%2BD28XitVWqt7c%3D (Pubitemid 43291222)
    • (2006) American Journal of Human Genetics , vol.78 , Issue.3 , pp. 393-400
    • Liu, X.1    Fu, Y.2    Liu, Z.3    Lin, B.4    Xie, Y.5    Liu, Y.6    Xu, Y.7    Lin, J.8    Fan, X.9    Dong, M.10    Zeng, K.11    Wu, C.-I.12    Xu, A.13
  • 42
    • 33645120407 scopus 로고    scopus 로고
    • Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer
    • 10.1038/sj.onc.1209375 16550166 10.1038/sj.onc.1209375 1:CAS:528:DC%2BD28XisFyhtbg%3D
    • S Nagar RP Remmel 2006 Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer Oncogene 25 1659 1672 10.1038/sj.onc.1209375 16550166 10.1038/sj.onc.1209375 1:CAS:528:DC%2BD28XisFyhtbg%3D
    • (2006) Oncogene , vol.25 , pp. 1659-1672
    • Nagar, S.1    Remmel, R.P.2
  • 43
    • 47949110575 scopus 로고    scopus 로고
    • Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines
    • 10.1124/dmd.108.021428 18480185 10.1124/dmd.108.021428 1:CAS:528:DC%2BD1cXptlanurk%3D
    • A Nakamura M Nakajima H Yamanaka R Fujiwara T Yokoi 2008 Expression of UGT1A and UGT2B mRNA in human normal tissues and various cell lines Drug Metab Dispos 36 1461 1464 10.1124/dmd.108.021428 18480185 10.1124/dmd.108.021428 1:CAS:528:DC%2BD1cXptlanurk%3D
    • (2008) Drug Metab Dispos , vol.36 , pp. 1461-1464
    • Nakamura, A.1    Nakajima, M.2    Yamanaka, H.3    Fujiwara, R.4    Yokoi, T.5
  • 44
    • 35348988170 scopus 로고    scopus 로고
    • Recent and ongoing selection in the human genome
    • DOI 10.1038/nrg2187, PII NRG2187
    • R Nielsen I Hellmann M Hubisz C Bustamante AG Clark 2007 Recent and ongoing selection in the human genome Nat Rev Genet 8 857 868 10.1038/nrg2187 17943193 10.1038/nrg2187 1:CAS:528:DC%2BD2sXhtFOksL7L (Pubitemid 47609088)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.11 , pp. 857-868
    • Nielsen, R.1    Hellmann, I.2    Hubisz, M.3    Bustamante, C.4    Clark, A.G.5
  • 46
    • 58149467072 scopus 로고    scopus 로고
    • Determination of mRNA expression of human UDP-glucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction
    • 10.1124/dmd.108.023598 18838504 10.1124/dmd.108.023598 1:CAS:528:DC%2BD1MXhsVSnuw%3D%3D
    • S Ohno S Nakajin 2009 Determination of mRNA expression of human UDP-glucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction Drug Metab Dispos 37 32 40 10.1124/dmd.108.023598 18838504 10.1124/dmd.108.023598 1:CAS:528:DC%2BD1MXhsVSnuw%3D%3D
    • (2009) Drug Metab Dispos , vol.37 , pp. 32-40
    • Ohno, S.1    Nakajin, S.2
  • 47
    • 82555177697 scopus 로고    scopus 로고
    • Introduction to endocrinology
    • D.G. Gardner D. Shoback (eds). 8 The McGraw-Hill Companies New York
    • Paul W, John BD (2007) Introduction to endocrinology. In: Gardner DG, Shoback D (eds) Greenspan's basic and clinical endocrinology, 8th edn. The McGraw-Hill Companies, New York, pp 1-34
    • (2007) Greenspan's Basic and Clinical Endocrinology , pp. 1-34
    • Paul, W.1    John, B.D.2
  • 51
    • 18144363991 scopus 로고    scopus 로고
    • Nucleotide sequence analyses of human complement 6 (C6) gene suggest balancing selection
    • DOI 10.1046/j.1529-8817.2005.00165.x
    • M Soejima H Tachida M Tsuneoka O Takenaka H Kimura Y Koda 2005 Nucleotide sequence analyses of human complement 6 (C6) gene suggest balancing selection Ann Hum Genet 69 239 252 10.1046/j.1529-8817.2005.00165.x 15845028 10.1046/J.1469-1809.2005.00165.x 1:CAS:528:DC%2BD2MXkvVensrw%3D (Pubitemid 40613725)
    • (2005) Annals of Human Genetics , vol.69 , Issue.3 , pp. 239-252
    • Soejima, M.1    Tachida, H.2    Tsuneoka, M.3    Takenaka, O.4    Kimura, H.5    Koda, Y.6
  • 53
    • 0242691208 scopus 로고    scopus 로고
    • A Comparison of Bayesian Methods for Haplotype Reconstruction from Population Genotype Data
    • DOI 10.1086/379378
    • M Stephens P Donnelly 2003 A comparison of bayesian methods for haplotype reconstruction from population genotype data Am J Hum Genet 73 1162 1169 10.1086/379378 14574645 10.1086/379378 1:CAS:528:DC%2BD3sXptVGnsL4%3D (Pubitemid 37414228)
    • (2003) American Journal of Human Genetics , vol.73 , Issue.5 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 54
    • 33644624797 scopus 로고    scopus 로고
    • Automating sequence-based detection and genotyping of SNPs from diploid samples
    • 10.1038/ng1746 16493422 10.1038/ng1746 1:CAS:528:DC%2BD28XhslCjt7w%3D
    • M Stephens JS Sloan PD Robertson P Scheet DA Nickerson 2006 Automating sequence-based detection and genotyping of SNPs from diploid samples Nat Genet 38 375 381 10.1038/ng1746 16493422 10.1038/ng1746 1:CAS:528:DC%2BD28XhslCjt7w%3D
    • (2006) Nat Genet , vol.38 , pp. 375-381
    • Stephens, M.1    Sloan, J.S.2    Robertson, P.D.3    Scheet, P.4    Nickerson, D.A.5
  • 55
    • 0021066244 scopus 로고
    • Evolutionary relationship of DNA sequences in finite populations
    • F Tajima 1983 Evolutionary relationship of DNA sequences in finite populations Genetics 105 437 460 6628982 1:CAS:528:DyaL3sXlsFCjs74%3D (Pubitemid 14247444)
    • (1983) Genetics , vol.105 , Issue.2 , pp. 437-460
    • Tajima, F.1
  • 56
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • F Tajima 1989 Statistical method for testing the neutral mutation hypothesis by DNA polymorphism Genetics 123 585 595 2513255 1:CAS:528: DyaK3cXhslentA%3D%3D (Pubitemid 19274682)
    • (1989) Genetics , vol.123 , Issue.3 , pp. 585-595
    • Tajima, F.1
  • 57
    • 28744446297 scopus 로고    scopus 로고
    • Evidence of balancing selection at the HLA-G promoter region
    • DOI 10.1093/hmg/ddi389
    • Z Tan AM Shon C Ober 2005 Evidence of balancing selection at the HLA-G promoter region Hum Mol Genet 14 3619 3628 10.1093/hmg/ddi389 16236759 10.1093/hmg/ddi389 1:CAS:528:DC%2BD2MXht1GgsrvN (Pubitemid 41754663)
    • (2005) Human Molecular Genetics , vol.14 , Issue.23 , pp. 3619-3628
    • Tan, Z.1    Shon, A.M.2    Ober, C.3
  • 58
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • DOI 10.1038/nature06258, PII NATURE06258
    • The International HapMap Consortium (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449:851-861. doi: 10.1038/nature06258 (Pubitemid 47598626)
    • (2007) Nature , vol.449 , Issue.7164 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3    Hinds, D.A.4
  • 59
    • 0024891561 scopus 로고
    • Endogenous oestrogens and androgens in normal and malignant endometrial and mammary tissues
    • DOI 10.1016/0277-5379(89)90377-5
    • JH Thijssen MA Blankenstein 1989 Endogenous oestrogens and androgens in normal and malignant endometrial and mammary tissues Eur J Cancer Clin Oncol 25 1953 1959 2632276 10.1016/0277-5379(89)90377-5 1:STN:280:DyaK3c3hsVKqsQ%3D%3D (Pubitemid 20084206)
    • (1989) European Journal of Cancer and Clinical Oncology , vol.25 , Issue.12 , pp. 1953-1959
    • Thijssen, J.H.H.1    Blankenstein, M.A.2
  • 60
    • 0030666150 scopus 로고    scopus 로고
    • Endogenous estrogen and postmenopausal breast cancer: A quantitative review
    • DOI 10.1023/A:1018476631561
    • HV Thomas GK Reeves TJ Key 1997 Endogenous estrogen and postmenopausal breast cancer: a quantitative review Cancer Causes Control 8 922 928 9427435 10.1023/A:1018476631561 1:STN:280:DyaK1c%2FoslejtQ%3D%3D (Pubitemid 27485468)
    • (1997) Cancer Causes and Control , vol.8 , Issue.6 , pp. 922-928
    • Thomas, H.V.1    Reeves, G.K.2    Key, T.J.A.3
  • 61
    • 0034128936 scopus 로고    scopus 로고
    • Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
    • DOI 10.1146/annurev.pharmtox.40.1.581
    • RH Tukey CP Strassburg 2000 Human UDP-glucuronosyltransferases: metabolism, expression, and disease Annu Rev Pharmacol Toxicol 40 581 616 10.1146/annurev.pharmtox.40.1.581 10836148 10.1146/annurev.pharmtox.40.1.581 1:CAS:528:DC%2BD3cXjs1yht7k%3D (Pubitemid 30340694)
    • (2000) Annual Review of Pharmacology and Toxicology , vol.40 , pp. 581-616
    • Tukey, R.H.1    Strassburg, C.P.2
  • 64
    • 33644981509 scopus 로고    scopus 로고
    • A map of recent positive selection in the human genome
    • 10.1371/journal.pbio.0040072 16494531 10.1371/journal.pbio.0040072
    • BF Voight S Kudaravalli X Wen JK Pritchard 2006 A map of recent positive selection in the human genome PLoS Biol 4 e72 10.1371/journal.pbio.0040072 16494531 10.1371/journal.pbio.0040072
    • (2006) PLoS Biol , vol.4 , pp. 72
    • Voight, B.F.1    Kudaravalli, S.2    Wen, X.3    Pritchard, J.K.4
  • 66
    • 0016491430 scopus 로고
    • On the number of segregating sites in genetical models without recombination
    • 1145509 10.1016/0040-5809(75)90020-9 1:STN:280:DyaE2M7pvFSquw%3D%3D
    • GA Watterson 1975 On the number of segregating sites in genetical models without recombination Theor Popul Biol 7 256 276 1145509 10.1016/0040-5809(75) 90020-9 1:STN:280:DyaE2M7pvFSquw%3D%3D
    • (1975) Theor Popul Biol , vol.7 , pp. 256-276
    • Watterson, G.A.1
  • 67
    • 0021566877 scopus 로고
    • Estimating F-statistics for the analysis of population structure
    • BS Weir CC Cockerham 1984 Estimating F-statistics for the analysis of population structure Evolution 38 1358 1370 10.2307/2408641 (Pubitemid 16277759)
    • (1984) Evolution , vol.38 , Issue.6 , pp. 1358-1370
    • Weir, B.S.1    Cockerham, C.C.2
  • 68
    • 0028781727 scopus 로고
    • Disorders of aldosterone biosynthesis and action
    • 8015573 10.1056/NEJM199412013312227 1:CAS:528:DyaK2cXmt1Ontro%3D
    • PC White 1994 Disorders of aldosterone biosynthesis and action N Engl J Med 331 250 258 8015573 10.1056/NEJM199412013312227 1:CAS:528:DyaK2cXmt1Ontro%3D
    • (1994) N Engl J Med , vol.331 , pp. 250-258
    • White, P.C.1
  • 69
    • 1842539589 scopus 로고    scopus 로고
    • Natural Selection and Molecular Evolution in PTC, a Bitter-Taste Receptor Gene
    • DOI 10.1086/383092
    • S Wooding UK Kim MJ Bamshad J Larsen LB Jorde D Drayna 2004 Natural selection and molecular evolution in PTC, a bitter-taste receptor gene Am J Hum Genet 74 637 646 10.1086/383092 14997422 10.1086/383092 1:CAS:528: DC%2BD2cXivFCnt74%3D (Pubitemid 38420094)
    • (2004) American Journal of Human Genetics , vol.74 , Issue.4 , pp. 637-646
    • Wooding, S.1    Kim, U.-K.2    Bamshad, M.J.3    Larsen, J.4    Jorde, L.B.5    Drayna, D.6
  • 70
    • 20944448714 scopus 로고
    • Genetical structure of populations
    • 15439261 10.1038/166247a0 1:STN:280:DyaG3c%2FkvVyqsQ%3D%3D
    • S Wright 1950 Genetical structure of populations Nature 166 247 249 15439261 10.1038/166247a0 1:STN:280:DyaG3c%2FkvVyqsQ%3D%3D
    • (1950) Nature , vol.166 , pp. 247-249
    • Wright, S.1
  • 72
    • 23144464155 scopus 로고    scopus 로고
    • Xenobiotic nuclear receptor-mediated regulation of UDP- glucuronosyltransferases
    • DOI 10.2174/1389200054633853
    • J Zhou J Zhang W Xie 2005 Xenobiotic nuclear receptor-mediated regulation of UDP-glucuronosyl-transferases Curr Drug Metab 6 289 298 16101569 10.2174/1389200054633853 1:CAS:528:DC%2BD2MXmvV2hsr8%3D (Pubitemid 41086763)
    • (2005) Current Drug Metabolism , vol.6 , Issue.4 , pp. 289-298
    • Zhou, J.1    Zhang, J.2    Xie, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.