Genetic variability in the ACE gene region surrounding the Alu I/D polymorphism is maintained by balancing selection in human populations

Pharmacogenetics and Genomics

Volumn 20, Issue 2, 2010, Pages 131-134

  Cagliani, Rachele ^a   Fumagalli, Matteo ^a,b   Riva, Stefania ^a   Pozzoli, Uberto ^a   Comi, Giacomo P ^c   Bresolin, Nereo ^a,c   Sironi, Manuela ^a  

^a SCIENTIFIC INSTITUTE   (Italy)

^b POLITECNICO DI MILANO   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Alu insertion deletion polymorphism; Angiotensin converting enzyme; Balancing selection

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

AFRICA; ARTICLE; CLADISTICS; GENE; GENE FREQUENCY; GENE FUNCTION; GENE LOCATION; GENEALOGY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INDEL MUTATION; INTERSPECIFIC RELATIONSHIP; NATURAL SELECTION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS;

ALU ELEMENTS; GENETIC VARIATION; GENETICS, POPULATION; HAPLOTYPES; HUMANS; INDEL MUTATION; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; SELECTION, GENETIC; TIME FACTORS;

EID: 75649146238     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283333532     Document Type: Article

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