Short term vs. long term test-retest reproducibility of 123I-ADAM for the binding of serotonin transporters in the human brain

Psychiatry Research - Neuroimaging

Volumn 194, Issue 3, 2011, Pages 224-229

  Hsu, Ju Wei ^a   Wang, Shyh Jen ^a   Lin, Chun Lung ^b   Hsieh, Wen Chi ^a   Lirng, Jiing Feng ^a   Shen, Yuh Chiang ^c   Liao, Mei Hsiu ^d   Chou, Yuan Hwa ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^d INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

Author keywords

123I ADAM; Circadian variation; Healthy subject; Reproducibility; Serotonin transporter; SPECT

Indexed keywords

ADAM I 123; RADIOPHARMACEUTICAL AGENT; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAUDATE NUCLEUS; CIRCADIAN RHYTHM; CORRELATION COEFFICIENT; CURVE FITTING; FEMALE; HUMAN; HUMAN EXPERIMENT; KRUSKAL WALLIS TEST; MALE; MESENCEPHALON; NEUROIMAGING; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PUTAMEN; REPRODUCIBILITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS; WILCOXON SIGNED RANKS TEST;

ADULT; BRAIN; BRAIN MAPPING; CINANSERIN; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PROTEIN BINDING; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STATISTICS, NONPARAMETRIC; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; YOUNG ADULT;

EID: 82455212882     PISSN: 09254927     EISSN: 18727506     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2011.04.011     Document Type: Article

References (36)

1. Acton P.D., Choi S.R., Hou C., Plossl K., Kung H.F. Quantification of serotonin transporters in nonhuman primates using [(123)I]ADAM and SPECT. Journal of Nuclear Medicine 2001, 42:1556-1562.
2. Amir S., Robinson B., Ratovitski T., Rea M.A., Stewart J., Simantov R. A role for serotonin in the circadian system revealed by the distribution of serotonin transporter and light-induced Fos immunoreactivity in the suprachiasmatic nucleus and intergeniculate leaflet. Neuroscience 1998, 84:1059-1073.
3. Butler S.G., Meegan M.J. Recent developments in the design of anti-depressive therapies: targeting the serotonin transporter. [Review] [153 refs]. Current Medicinal Chemistry 2008, 15:1737-1761.
4. Carlsson A., Svennerholm L., Winblad B. Seasonal and circadian monoamine variations in human brains examined post mortem. Acta Psychiatrica Scandinavica, Supplementum 1980, 280:75-85.
5. Catafau A.M., Perez V., Penengo M.M., Bullich S., Danus M., Puigdemont D., Pascual J.C., Corripio I., Llop J., Perich J., Alvarez E. SPECT of serotonin transporters using 123I-ADAM: optimal imaging time after bolus injection and long-term test-retest in healthy volunteers. Journal of Nuclear Medicine 2005, 46:1301-1309.
6. Chou Y.H., Huang W.S., Su T.P., Lu R.B., Wan F.J., Fu Y.K. Dopamine transporters and cognitive function in methamphetamine abuser after a short abstinence: a SPECT study. European Neuropsychopharmacology 2007, 17:46-52.
7. Chou Y.H., Karlsson P., Halldin C., Olsson H., Farde L. A PET study of D1-like dopamine receptor ligand binding. Psychopharmacology 1999, 146:220-227.
8. Chou, Y.H., Wang, S.J., Lin, C.L., Mao, W.C., Lee, S.M., Liao, M.H., 2010. Decreased brain serotonin transporter binding in the euthymic state of bipolar I but not bipolar II disorder: a SPECT study. Bipolar Disorders 12 (3), 312-318.
9. Chou Y.H., Yang B.H., Chung M.Y., Chen S.P., Su T.P., Chen C.C., Wang S.J. Imaging the serotonin transporter using (123)I-ADAM in the human brain. Psychiatry Research Neuroimage 2009, 172:38-43.
10. Daws L.C. Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy. Pharmacology & Therapeutics 2009, 121:89-99.
11. Farde L., Eriksson L., Blomquist G., Halldin C. Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET-a comparison to the equilibrium analysis. Journal of Cerebral Blood Flow and Metabolism 1989, 9:696-708.
12. Farde L., Hall H., Ehrin E., Sedvall G. Quantitative analysis of D2 dopamine receptor binding in the living human brain by PET. Science 1986, 231:258-261.
13. Frokjaer V.G., Pinborg L.H., Madsen J., de Nijs R., Svarer C., Wagner A., Knudsen G.M. Evaluation of the serotonin transporter ligand 123I-ADAM for SPECT studies on humans. Journal of Nuclear Medicine 2008, 49:247-254.
14. Kalbitzer J., Erritzoe D., Holst K.K., Nielsen F.A., Marner L., Lehel S., Arentzen T., Jernigan T.L., Knudsen G.M. Seasonal changes in brain serotonin transporter binding in short serotonin transporter linked polymorphic region-allele carriers but not in long-allele homozygotes. Biological Psychiatry 2010, 67:1033-1039.
15. Klein N., Sacher J., Geiss-Granadia T., Attarbaschi T., Mossaheb N., Lanzenberger R., Potzi C., Holik A., Spindelegger C., Asenbaum S., Dudczak R., Tauscher J., Kasper S. In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram. Psychopharmacology 2006, 188:263-272.
16. Koskela A., Kauppinen T., Keski-Rahkonen A., Sihvola E., Kaprio J., Rissanen A., Ahonen A. Brain serotonin transporter binding of [123I]ADAM: within-subject variation between summer and winter data. Chronobiology International 2008, 25:657-665.
17. Kung M.P., Hou C., Oya S., Mu M., Acton P.D., Kung H.F. Characterization of [(123)I]IDAM as a novel single-photon emission tomography tracer for serotonin transporters. European Journal of Nuclear Medicine 1999, 26:844-853.
18. Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., Benjamin J., Muller C.R., Hamer D.H., Murphy D.L. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996, 274:1527-1531. [see comment].
19. Lucki I. The spectrum of behaviors influenced by serotonin. Biological Psychiatry 1998, 44:151-162.
20. Maswood S., Truitt W., Hotema M., Caldarola-Pastuszka M., Uphouse L. Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonin transporter and terminal autoreceptors. Brain Research 1999, 831:146-154.
21. Miller J.D., Morin L.P., Schwartz W.J., Moore R.Y. New insights into the mammalian circadian clock. Sleep 1996, 19:641-667. [Review] [230 refs].
22. Neumeister A., Konstantinidis A., Praschak-Rieder N., Willeit M., Hilger E., Stastny J., Kasper S. Monoaminergic function in the pathogenesis of seasonal affective disorder. The International Journal of Neuropsychopharmacology 2001, 4:409-420. [Review] [110 refs].
23. Neumeister A., Pirker W., Willeit M., Praschak-Rieder N., Asenbaum S., Brucke T., Kasper S. Seasonal variation of availability of serotonin transporter binding sites in healthy female subjects as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biological Psychiatry 2000, 47:158-160.
24. Newberg A.B., Amsterdam J.D., Wintering N., Ploessl K., Swanson R.L., Shults J., Alavi A. 123I-ADAM binding to serotonin transporters in patients with major depression and healthy controls: a preliminary study. Journal of Nuclear Medicine 2005, 46:973-977.
25. Oya S., Choi S.R., Hou C., Mu M., Kung M.P., Acton P.D., Siciliano M., Kung H.F. 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nuclear Medicine and Biology 2000, 27:249-254.
26. Praschak-Rieder N., Willeit M., Wilson A.A., Houle S., Meyer J.H. Seasonal variation in human brain serotonin transporter binding. Archives of General Psychiatry 2008, 65:1072-1078.
27. Praschak-Rieder N., Wilson A.A., Hussey D., Carella A., Wei C., Ginovart N., Schwarz M.J., Zach J., Houle S., Meyer J.H. Effects of tryptophan depletion on the serotonin transporter in healthy humans. Biological Psychiatry 2005, 58:825-830.
28. Ruhe H.G., Booij J., Reitsma J.B., Schene A.H. Serotonin transporter binding with [123I]beta-CIT SPECT in major depressive disorder versus controls: effect of season and gender. European Journal of Nuclear Medicine and Molecular Imaging 2009, 36:841-849.
29. Seeman P., Guan H.C., Niznik H.B. Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: implications for positron emission tomography of the human brain. Synapse 1989, 3:96-97.
30. Sobczak S., Honig A., van Duinen M.A., Riedel W.J. Serotonergic dysregulation in bipolar disorders: a literature review of serotonergic challenge studies. Bipolar Disorders 2002, 4:347-356. [Review] [100 refs].
31. Talbot P.S., Frankle W.G., Hwang D.-R., Huang Y., Suckow R.F., Slifstein M., Abi-Dargham A., Laruelle M. Effects of reduced endogenous 5-HT on the in vivo binding of the serotonin transporter radioligand 11C-DASB in healthy humans. Synapse 2005, 55:164-175.
32. Varrone A., Fujita M., Verhoeff N.P., Zoghbi S.S., Baldwin R.M., Rajeevan N., Charney D.S., Seibyl J.P., Innis R.B. Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans. Journal of Nuclear Medicine 2000, 41:1343-1351.
33. Willeit M., Sitte H.H., Thierry N., Michalek K., Praschak-Rieder N., Zill P., Winkler D., Brannath W., Fischer M.B., Bondy B., Kasper S., Singer E.A. Enhanced serotonin transporter function during depression in seasonal affective disorder. Neuropsychopharmacology 2008, 33:1503-1513.
34. Yamamoto S., Onoe H., Tsukada H., Watanabe Y. Effects of increased endogenous serotonin on the in vivo binding of [11C]DASB to serotonin transporters in conscious monkey brain. Synapse 2007, 61:724-731.
35. Zhou D., Huether G., Wiltfang J., Hajak G., Ruther E. Serotonin transporters in the rat frontal cortex: lack of circadian rhythmicity but down-regulation by food restriction. Journal of Neurochemistry 1996, 67:656-661.
36. Zipursky R.B., Meyer J.H., Verhoeff N.P. PET and SPECT imaging in psychiatric disorders. Canadian Journal of Psychiatry - Revue Canadienne de Psychiatrie 2007, 52:146-157.